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POP4 Gene

protein-coding   GIFtS: 53

GC19P026609
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)1 2
RPP291 2 3 5
hPOP42 3
ribonuclease P protein subunit p292
EC 3.1.26.53

External Ids:    HGNC: 300811   Entrez Gene: 107752   Ensembl: ENSG000001051717   UniProtKB: O957073   

Export aliases for POP4 gene to outside databases

Previous GC identifers: GC19P030719 GC19P030546 GC19P034773 GC19P034789 GC19P030097


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for POP4:
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease
for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the
nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of
precursor RNAs. Alternative splicing results in multiple transcript variants. (provided by RefSeq)

UniProtKB/Swiss-Prot: RPP29_HUMAN, O95707
Function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May
function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P

Gene Wiki entry for POP4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POP4 gene promoter:
         TGIF   ISGF-3   GATA-1   c-Jun   c-Fos   AP-1   STAT6   STAT5A   STAT4   STAT3   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for POP4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for POP4 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q12   Ensembl cytogenetic band:  19q12   HGNC cytogenetic band: 19q13.11

POP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POP4 gene location

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P026609:  view genomic region     (about GC identifiers)

Start:
26,609,015 bp from pter
End:
26,620,008 bp from pter
Size:
10,994 bases
Orientation:
plus strand

1 alternative location:
Chr19+ 30,097,201-30,106,706     
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: RPP29_HUMAN, O95707 (See protein sequence)
Recommended Name: Ribonuclease P protein subunit p29  
Size: 220 amino acids; 25425 Da
Subunit: Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of a RNA moiety and at least 8
protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of a RNA
moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and
RPP21. Interacts with RPP25 and POP5
Subcellular location: Nucleus, nucleolus
Secondary accessions: Q5XKL7 Q6FHW9 Q9UQQ3

Explore the universe of human proteins at neXtProt for POP4: NX_O95707 

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_006618.1  

    ENSEMBL proteins: 
    ENSP00000376104 ENSP00000221770 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: POP4
    GenScript Custom Purified and Recombinant Proteins Services for POP4 
    Novus Biologicals Proteins for POP4
    Novus Biologicals Lysate for POP4
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000172 ribonuclease MRP complex IEA--
    GO:0005634 nucleus IEA--
    GO:0005655 nucleolar ribonuclease P complex IEA--
    GO:0005730 nucleolus IEA--
    GO:0030677 ribonuclease P complex IEA--
    About this table

    POP4 for ontologies           About GeneDecksing



    Antibodies for POP4: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for POP4
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for POP4 
    Novus Biologicals Antibody for POP4
    Browse antibodies at Epitomics

    Assays for POP4: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for POP4 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for POP4 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    POP4 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR016848 RNase_P/MRP_p29-subunit_euk
     IPR002730 RNase_P/MRP_p29_euk/arc

    Graphical View of Domain Structure for InterPro Entry O95707

    ProtoNet protein and cluster: O95707

    1 Blocks protein family: IPB002730 Protein of unknown function UPF0086

    UniProtKB/Swiss-Prot: RPP29_HUMAN, O95707
    Similarity: Belongs to the eukaryotic/archaeal RNase P protein component 1 family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: RPP29_HUMAN, O95707
    Function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May
    function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P
    Catalytic activity: Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
    Enzyme Number (IUBMB): EC 3.1.26.5 

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for POP4
    Sigma-Aldrich shRNA for POP4
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): POP4
    OriGene shRNA RFP (see all 3): POP4
    OriGene basic RS shRNA (see all 3): POP4
    OriGene siRNA (see all 3): POP4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of POP4 
    miRNA:Sigma-Aldrich microRNA Mimics for POP4
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of POP4 
    Search SABiosciences for Assays for microRNAs that regulate POP4

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: POP4
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: POP4
    OriGene untagged cDNA clones in CMV expression vector: POP4
    OriGene 3'-UTR clone: POP4 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for POP4 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for POP4 

    5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723 RNA binding IEA--
    GO:0004526 ribonuclease P activity IEA--
    GO:0004540 ribonuclease activity IEA--
    GO:0005515 protein binding IPI15096576
    GO:0016787 hydrolase activity IEA--
    About this table

    POP4 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    POP4 for pathways           About GeneDecksing

    1 Kegg Pathway  (Kegg details for POP4):
        hsa03013 RNA transport

        SABiosciences Custom Pathway-Focused PCR Arrays for POP4 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POP4

    5/6 Interacting proteins for POP4 (O957071 ENSP000002217703) via UniProtKB, MINT, and/or STRING (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POP5Q969H61, ENSP000003500983EBI-366477,EBI-366525 STRING: ENSP00000350098
    RPP38P783451, ENSP000003674443EBI-366477,EBI-366493 STRING: ENSP00000367444
    POP1Q995751EBI-366477,EBI-366741
    POP4O957071EBI-366477,EBI-366477
    RPP14O950591EBI-366477,EBI-366542
    About this table

    3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364 rRNA processing IEA--
    GO:0006379 mRNA cleavage IEA--
    GO:0008033 tRNA processing IEA--
    About this table

    POP4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for POP4


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for POP4
    Sigma-Aldrich shRNA for POP4
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): POP4
    OriGene shRNA RFP (see all 3): POP4
    OriGene basic RS shRNA (see all 3): POP4
    OriGene siRNA (see all 3): POP4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of POP4 
    miRNA: Sigma-Aldrich microRNA Mimics for POP4
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of POP4 
    Search SABiosciences for Assays for microRNAs that regulate POP4
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: POP4
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: POP4
    OriGene untagged cDNA clones in CMV expression vector: POP4
    OriGene 3'-UTR Clone: POP4 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for POP4 
    Primers: OriGene genome-wide validated SYBR primer pairs: POP4
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for POP4: PPH19611A

    REFSEQ mRNAs for POP4 gene: 

    NM_006627.2  

    Additional cDNA sequence: 

    AF001176.2 AK090872.1 AK314790.1 BC004438.1 BC006098.1 BC013686.1 CR536569.1 CR620341.1 
    CR624820.1 CR936714.1 Y18863.1 

    12 DOTS entries:

    DT.219248  DT.92021320  DT.311374  DT.75172550  DT.121489407  DT.99933112  DT.121489402  DT.95197196 
    DT.121489345  DT.92392293  DT.92435932  DT.95197195 

    24/277 AceView cDNA sequences (see all 277):

    BQ428458 BE514692 BM750755 BM461646 BM726033 AI091498 CB163102 CR620341 
    BM766302 CB141662 BM985094 BE746054 AA934656 AA987278 CA314143 BE263449 
    BF434997 CA413556 BI116633 CD673378 BG697335 AA570404 BQ082298 CD370529 

    highest scoring ESTs for POP4:

    Y18863 AA047381 AA074534 AA074975 AA082498 AA132960 AA132996 AA134866 AA150967 AA151076 

    Unigene Cluster for POP4:

    Processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
    Hs.412870  [show with all ESTs]
    Unigene Representative Sequence: NM_006627


    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for POP4 (see all 12)

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d · 10e · 10f
    SP1:              -           -     -     -     -     -                 -                 -     -                                                   
    SP2:                          -     -                 -                 -                                                                           
    SP3:              -           -     -     -     -     -           -     -     -           -     -                                                   
    SP4:              -           -     -     -     -     -                 -                 -     -                                                   
    SP5:                                                  -                 -                 -     -                                                   

    About this scheme

    ECgene alternative splicing isoforms for POP4
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392279 ENST00000221770(uc002nsf.2 uc002nsg.2)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    POP4 expression in normal and diseased human tissues

    1  / 2  / 3

    5 probe-sets matching POP4 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    38380_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 Y18863 1.00 1.00 1.00 1
    202868_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_006627 0.60 1.00 0.82 1
    227583_at2, 3 U133-B 1 0.36 1.00 -- -- BE742653 0.40 1.00 0.76 1
    202868_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    227583_at2 U133Plus2 1 0.36 1.00 -- -- -- -- -- -- --
    About this table

    POP4 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    POP4 gene expression
    POP4 gene electronic northern expression
    POP4 gene sage expression
    About these images

    CGAP SAGE TAG: TTTTCTGAGT

    SOURCE GeneReport for Unigene cluster: Hs.412870

    Expression variation in blood from EXPOLDB for POP4

    Primers: OriGene genome-wide validated SYBR primer pairs: POP4
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for POP4: PPH19611A
        SABiosciences Custom PCR Arrays for POP4 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for POP4 gene from 5/14 species (see all 14)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    POP41   -- processing of precursor 4, ribonuclease P/MRP subunit more 87.29(n)
    87.91(a)
    612732  XM_850448.1  XP_855541.1 
    chimpanzee
    (Pan troglodytes)
    POP41   -- processing of precursor 4, ribonuclease P/MRP subunit more 99.55(n)
    99.55(a)
    456386  XM_512983.2  XP_512983.2 
    cow
    (Bos taurus)
    POP41   -- processing of precursor 4, ribonuclease P/MRP subunit more 88.95(n)
    92.27(a)
    614870  NM_001034770.1  NP_001029942.1 
    rat
    (Rattus norvegicus)
    Pop41   -- processing of precursor 4, ribonuclease P/MRP subunit more 84.55(n)
    85(a)
    292831  NM_001009642.1  NP_001009642.1 
    mouse
    (Mus musculus)
    Pop41 , 5 7 (25.36 cM)5
    processing of precursor 4, ribonuclease P/MRP family, more1, 5 82.88(n)1
    83.18(a)1
    661611  NM_025390.31  NP_079666.11 
     AI8464935  AK0028555  (see all 14)
    About this table        Species with no ortholog for POP4

    ENSEMBL Gene Tree for POP4 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/170 NCBI SNPs in POP4 are shown (see all 170)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 19 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs72831,2
    C,F,A,H,30106659(-) ATGTAC/TTGTAT 2 -- ut3133Minor allele frequency- T:0.39MN NA NS EA WA 2684
    rs137671,2
    C,F,30106189(+) AAACCG/AATGGC 4 /N /D mis1 ref14Minor allele frequency- A:0.01NS EA 420
    rs8910601,2
    C,F,A,30102283(+) ACAGGA/GTATCA 1 -- int114Minor allele frequency- G:0.32NA EA MN NS 1188
    rs8910611,2
    C,F,O,A,30102477(+) AACCTC/TAAAAT 1 -- int120Minor allele frequency- T:0.50NA EA NS WA 1300
    rs9781731,2
    C,F,30102386(+) ACCAGC/ACTGCT 1 -- int16Minor allele frequency- A:0.01MN NS EA WA 654
    rs14655851,2
    C,30099457(+) caggtG/Atgagc 1 -- int17Minor allele frequency- A:0.07NA WA 14
    rs20429681,2
    C,F,30106775(+) GAGGCT/ACGCCT 1 -- ut316Minor allele frequency- A:0.45EA NS NA 344
    rs20429691,2
    C,F,O,A,30107422(+) GCGTTT/CCTGGT 1 -- ut3111Minor allele frequency- C:0.40NS EA NA WA 518
    rs20429701,2
    C,F,O,A,30107621(+) TCCTCC/TGCTCA 1 -- ut3114Minor allele frequency- T:0.37MN EA NS NA WA 844
    rs21153701,2
    C,F,A,30106891(+) AATCAT/CAGCTG 1 -- ut3115Minor allele frequency- C:0.36NS EA NA WA 1054
    About this table

    HapMap Linkage Disequilibrium images for POP4 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for POP4: --

    QIAGEN SeqTarget long-range PCR primers for resequencing POP4 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    POP4 for disorders           About GeneDecksing

    OMIM: 606114


    Export disorders and mutations for POP4 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/18 PubMed articles for POP4 gene, integrated from 7 sources (see all 18):
    (articles sorted by number of sources associating them with POP4)
    1. Rpp14 and Rpp29, two protein subunits of human ribonuclease P. (PubMed id 10024167)1, 2, 3, 7 Jarrous N.... Altman S. (1999)
    2. hPop4: a new protein subunit of the human RNase MRP and RNase P ribonucleoprotein complexes. (PubMed id 10352175)1, 2, 3, 7 van Eenennaam H.... van Venrooij W.J. (1999)
    3. Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. (PubMed id 15096576)1, 2 Welting T.J.... Pruijn G.J. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Inhibition of the expression of the human RNase P protein subunits Rpp21, Rpp25, Rpp29 by external guide sequences (EGSs) and siRNA. (PubMed id 15351636)1, 7 Zhang H. and Altman S. (2004)
    6. Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS spectra. (PubMed id 17924679)2 Yu L.-R.... Veenstra T.D. (2007)
    7. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)2 Matsuoka S.... Elledge S.J. (2007)
    8. Differential association of protein subunits with the human RNase MRP and RNase P complexes. (PubMed id 16723659)1 Welting T.J....Pruijn G.J. (2006)
    9. Nucleolar proteome dynamics. (PubMed id 15635413)1 Andersen J.S....Mann M. (2005)
    10. RNase P: role of distinct protein cofactors in tRNA substrate recognition and RNA-based catalysis. (PubMed id 16155184)1 Sharin E....Jarrous N. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10775 HGNC: 30081 AceView: POP4 Ensembl:ENSG00000105171 euGenes: HUgn10775
    ECgene: POP4 Kegg: 10775 H-InvDB: POP4

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    Patent Information for POP4 gene:
    Search GeneIP for patents involving POP4

    GeneCards and IP:
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     ELISAs and CLIAs for POP4
           

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