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PPFIBP2 Gene

protein-coding   GIFtS: 52

GC11P007193
PTPRF interacting protein, binding protein 2 (liprin beta 2)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
PTPRF interacting protein, binding protein 2 (liprin beta 2)1 2     DKFZp781K061262
Cclp11 2     liprin-beta-22
Protein tyrosine phosphatase receptor type f polypeptide-interacting
protein-binding protein 22 3
     MGC425412
PTPRF-interacting protein-binding protein 22 3     

External Ids:    HGNC: 92501   Entrez Gene: 84952   Ensembl: ENSG000001663877   UniProtKB: Q8ND303   

Export aliases for PPFIBP2 gene to outside databases

Previous GC identifers: GC11P008370 GC11P007995 GC11P007494 GC11P007499 GC11P007491


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PPFIBP2:
PPFIBP2, or liprin-beta-2, belongs to the liprin-beta family. See liprin-beta-1 (MIM 603141) for background on
liprins.(supplied by OMIM)

UniProtKB/Swiss-Prot: LIPB2_HUMAN, Q8ND30
Function: May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPFIBP2 gene promoter:
         Chx10   Max1   c-Myc   MEF-2A   FOXC1   USF1   NF-E2 p45   NF-E2   E47   E2F-1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for PPFIBP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for PPFIBP2 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

PPFIBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPFIBP2 gene location

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P007193:  view genomic region     (about GC identifiers)

Start:
7,193,533 bp from pter
End:
7,333,709 bp from pter
Size:
140,177 bases
Orientation:
plus strand

1 alternative location:
Chr11+ 7,535,001-7,674,989     
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: LIPB2_HUMAN, Q8ND30 (See protein sequence)
Recommended Name: Liprin-beta-2  
Size: 876 amino acids; 98544 Da
Subunit: Forms homodimers and heterodimers (By similarity)
Secondary accessions: O75337 Q8WW26

Explore the universe of human proteins at neXtProt for PPFIBP2: NX_Q8ND30 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_003612.2  

    ENSEMBL proteins: 
    ENSP00000299492 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: PPFIBP2
    GenScript Custom Purified and Recombinant Proteins Services for PPFIBP2 
    Novus Biologicals Proteins for PPFIBP2
    Novus Biologicals Lysates for PPFIBP2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular TAS9624153
    About this table

    PPFIBP2 for ontologies           About GeneDecksing



    Antibodies for PPFIBP2: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for PPFIBP2
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for PPFIBP2 
    Novus Biologicals Antibodies for PPFIBP2
    Epitomics antibodies for PPFIBP2

    Assays for PPFIBP2: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PPFIBP2 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for PPFIBP2 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PPFIBP2 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR010993 Sterile_alpha_motif_homology
     IPR021129 SAM_type1
     IPR004191 Integrase_Tn916-type_DNA-bd_N
     IPR013761 SAM_type
     IPR001660 SAM

    Graphical View of Domain Structure for InterPro Entry Q8ND30

    ProtoNet protein and cluster: Q8ND30

    3 Blocks protein families:
    IPB001660 Sterile alpha motif SAM
    IPB004191 Tn916 integrase
    IPB011510 Sterile alpha motif homology 2


    UniProtKB/Swiss-Prot: LIPB2_HUMAN, Q8ND30
    Domain: The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type
    beta/beta. The C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha (By similarity)
    Similarity: Belongs to the liprin family. Liprin-beta subfamily
    Similarity: Contains 3 SAM (sterile alpha motif) domains


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: LIPB2_HUMAN, Q8ND30
    Function: May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for PPFIBP2
    Sigma-Aldrich shRNA for PPFIBP2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): PPFIBP2
    OriGene shRNA RFP (see all 3): PPFIBP2
    OriGene basic RS shRNA (see all 3): PPFIBP2
    OriGene siRNA (see all 2): PPFIBP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PPFIBP2 
    miRNA:Sigma-Aldrich microRNA Mimics for PPFIBP2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PPFIBP2 
    3 SABiosciences Assays for microRNAs that regulate PPFIBP2:
    hsa-miR-182 hsa-miR-124 hsa-miR-506

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: PPFIBP2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PPFIBP2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): PPFIBP2
    OriGene 3'-UTR clone: PPFIBP2 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for PPFIBP2 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for PPFIBP2 

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674 molecular_function ND--
    GO:0003677 DNA binding IEA--
    GO:0005515 protein binding IPI18482256
    GO:0008907 integrase activity IEA--
    About this table

    PPFIBP2 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for PPFIBP2 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPFIBP2

    4 Interacting proteins for PPFIBP2 (Q8ND301, 2) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRNPP041561EBI-744056,EBI-977302
    SFNP319472MINT-3975178
    TSG101Q998162MINT-66433
    --Q96AW02MINT-68284
    About this table

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007154 cell communication NAS--
    GO:0015074 DNA integration IEA--
    About this table

    PPFIBP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPFIBP2


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for PPFIBP2
    Sigma-Aldrich shRNA for PPFIBP2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): PPFIBP2
    OriGene shRNA RFP (see all 3): PPFIBP2
    OriGene basic RS shRNA (see all 3): PPFIBP2
    OriGene siRNA (see all 2): PPFIBP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PPFIBP2 
    miRNA: Sigma-Aldrich microRNA Mimics for PPFIBP2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PPFIBP2 
    3 SABiosciences Assays for microRNAs that regulate PPFIBP2:
    hsa-miR-182 hsa-miR-124 hsa-miR-506
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: PPFIBP2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PPFIBP2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): PPFIBP2
    OriGene 3'-UTR Clone: PPFIBP2 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for PPFIBP2 
    Primers: OriGene genome-wide validated SYBR primer pairs: PPFIBP2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PPFIBP2: PPH07898A

    REFSEQ mRNAs for PPFIBP2 gene: 

    NM_003621.2  

    Additional cDNA sequence: 

    AF034803.1 AK001131.1 AK025337.1 AK097449.1 AK293669.1 AK294554.1 AK296718.1 AK301978.1 
    AK308398.1 AK311048.1 AL834426.1 BC021026.1 BC021714.1 CR749258.1 

    20 DOTS entries:

    DT.452999  DT.100009989  DT.100787630  DT.91650802  DT.100787632  DT.95307781  DT.100787633  DT.100787637 
    DT.425417  DT.95145072  DT.120748187  DT.100809764  DT.120748153  DT.120748231  DT.40190437  DT.120748192 
    DT.75159030  DT.92027374  DT.120748173  DT.95195773 

    24/205 AceView cDNA sequences (see all 205):

    CD109093 BX109147 AI868399 BF726125 BU624376 AA877353 AL834426 AA331841 
    AI057485 CB161350 AI692180 BF726124 CD171856 CB129260 CD364931 BM682279 
    AI149790 AI805241 AA583006 CA503137 AW576293 R72196 AU146640 AA815324 

    highest scoring ESTs for PPFIBP2:

    AF034803 AA131100 AA502582 AA551750 AA583006 AA598564 AA760889 AA781767 AA804778 AA815324 

    Unigene Cluster for PPFIBP2:

    PTPRF interacting protein, binding protein 2 (liprin beta 2)
    Hs.655714  [show with all ESTs]
    Unigene Representative Sequence: NM_003621


    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PPFIBP2 (see all 12)

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^
    SP1:                                                                                                                                                  -         
    SP2:                    -     -     -                                   -                 -     -                                                               
    SP3:                          -     -                                   -                                                                                       
    SP4:                                                                                                                                                            
    SP5:                    -     -                                                                                                                                 

    ExUns: 19 ^ 20 ^ 21a · 21b ^ 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31
    SP1:                                -                                   -                                 
    SP2:                                                                                                      
    SP3:                                                                                                      
    SP4:                                                                                                      
    SP5:                                                                                                      

    About this scheme

    ECgene alternative splicing isoforms for PPFIBP2
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000299492(uc010rbd.1 uc010rbb.1 uc001mfk.1 uc001mfj.3 uc010rbc.1 uc010rbe.1 uc001mfl.3 uc009yfj.1)


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    PPFIBP2 expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching PPFIBP2 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    41709_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AF034803 1.00 1.00 1.00 1
    212841_s_at2, 3 U133-A 1 1.00 1.00 -- -- AI692180 0.80 1.00 0.91 1
    212841_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    PPFIBP2 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    PPFIBP2 gene expression
    PPFIBP2 gene electronic northern expression
    PPFIBP2 gene sage expression
    About these images

    CGAP SAGE TAG: GACACTCCCA

    SOURCE GeneReport for Unigene cluster: Hs.655714

    Expression variation in blood from EXPOLDB for PPFIBP2

    UniProtKB/Swiss-Prot: LIPB2_HUMAN, Q8ND30
    Tissue specificity: Widely expressed

    Primers: OriGene genome-wide validated SYBR primer pairs: PPFIBP2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PPFIBP2: PPH07898A
        SABiosciences Custom PCR Arrays for PPFIBP2 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for PPFIBP2 gene from 5/10 species (see all 10)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    PPFIBP21   -- PTPRF interacting protein, binding protein 2 (liprin more 90.59(n)
    92.65(a)
    485366  XM_542484.2  XP_542484.2 
    chimpanzee
    (Pan troglodytes)
    PPFIBP21   -- PTPRF interacting protein, binding protein 2 (liprin more 99.39(n)
    99.08(a)
    749024  XM_001164875.1  XP_001164875.1 
    cow
    (Bos taurus)
    PPFIBP21   -- PTPRF interacting protein, binding protein 2 (liprin more 87.45(n)
    88.33(a)
    614705  XM_866292.2  XP_871385.2 
    rat
    (Rattus norvegicus)
    Ppfibp21   -- PTPRF interacting protein, binding protein 2 (liprin more 87.56(n)
    90.04(a)
    308918  XM_219201.4  XP_219201.4 
    mouse
    (Mus musculus)
    Ppfibp21 , 5 7 (57.21 cM)5
    PTPRF interacting protein, binding protein 2 (liprin more5
    protein tyrosine phosphatase, receptor-type, F interacting more1
    87.51(n)1
    89.89(a)1
    190241  NM_008905.11  NP_032931.11 
     AK0121525  AK0353645  (see all 21)
    About this table        Species with no ortholog for PPFIBP2

    ENSEMBL Gene Tree for PPFIBP2 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for PPFIBP2 gene
    PPFIBP12  PPFIA22  PPFIA42  KAZ2  PPFIA32  PPFIA12  

    PPFIBP2 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/1712 NCBI SNPs in PPFIBP2 are shown (see all 1712)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs58641,2
    C,F,A,7673015(+) CAGGAA/GAAGCG 2 E syn1 ref118Minor allele frequency- G:0.34NS EA NA MN WA 1386
    rs136071,2
    --7674701(+) TTTTAC/AATGTC 1 -- ut31 ese31Minor allele frequency- A:0.00MN 184
    rs10790251,2
    C,7596197(+) TTCTTC/GCCTCC 1 -- int1 trp30--------
    rs11280121,2
    F7674401(+) CCCCTT/GGATGC 2 /L syn1 ref11Minor allele frequency- G:0.07MN 184
    rs11376221,2
    --7601092(+) AAACTC/TAAAGT 1 -- int10--------
    rs38610661,2
    C,F,A,7663779(+) TCTTCC/TCCAGT 1 -- int1 trp311Minor allele frequency- T:0.34NS EA NA WA 766
    rs38899801,2
    C,7595965(+) GTGAGC/TGAGGA 1 -- int14Minor allele frequency- T:0.00NS EA 404
    rs38923351,2
    C,F,7627786(-) AATAAC/TAGAAC 1 -- int120Minor allele frequency- T:0.37NS EA NA WA 1272
    rs38925691,2
    C,F,7596387(+) CTTTAC/ACAGTC 1 -- int16Minor allele frequency- A:0.04NA 394
    rs39234911,2
    C,F,A,H,7672272(-) TTGTGT/CCTTGT 1 -- int121Minor allele frequency- C:0.31NS EA NA WA 1266
    About this table

    HapMap Linkage Disequilibrium images for PPFIBP2 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PPFIBP2: --

    QIAGEN SeqTarget long-range PCR primers for resequencing PPFIBP2 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PPFIBP2 for disorders           About GeneDecksing

    OMIM: 603142

    Human Genome Epidemiology (HuGE) Navigator: PPFIBP2 (2 documents)

    Export disorders and mutations for PPFIBP2 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/13 PubMed articles for PPFIBP2 gene, integrated from 7 sources (see all 13):
    (articles sorted by number of sources associating them with PPFIBP2)
    1. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins. (PubMed id 9624153)1, 2, 3 Serra-Pages C.... Streuli M. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    4. Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists. (PubMed id 20095854)1 Bhatti P....Sigurdson A.J. (2010)
    5. Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)1 Satoh J....Tabunoki H. (2009)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8495 HGNC: 9250 AceView: PPFIBP2 Ensembl:ENSG00000166387 euGenes: HUgn8495
    ECgene: PPFIBP2 H-InvDB: PPFIBP2

    (According to HUGE)
    About This Section
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    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    Patent Information for PPFIBP2 gene:
    Search GeneIP for patents involving PPFIBP2

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