Aliases &
Descriptions
for PRAMEF22 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| PRAME family member 221 2 | | PRAMEF3L1 2 | | PRAME family member 3-like2 |
Export aliases for PRAMEF22 gene to outside databasesPrevious GC identifers: GC01P012957 GC01P012958 |
Summaries
for PRAMEF22 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
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|
-- |
Genomic Views
for PRAMEF22 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for PRAMEF22
Other transcription factors
Search SABiosciences Chromatin IP Primers for PRAMEF22
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.21 Ensembl cytogenetic band: 1p36.21 HGNC cytogenetic band: 1p36.21PRAMEF22 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P013035: view genomic region
(about GC identifiers)
Start:
|
13,035,543 bp from pter |
End:
|
13,038,381 bp from pter |
Size:
|
2,839 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000001.10 NT_021937.19
|
Proteins
for PRAMEF22 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
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|
UniProtKB/Swiss-Prot: PRA22_HUMAN, A3QJZ6 (See
protein sequence)Recommended Name: PRAME family member 22 Size: 481 amino acids; 55489 Da
Caution: It is uncertain whether Met-1 or Met-3 is the initiator
Secondary accessions: A6NMM3Explore the universe of human proteins at neXtProt for PRAMEF22: NX_A3QJZ6
REFSEQ proteins: NP_001094101.1
ENSEMBL proteins: ENSP00000365358
Human Recombinant Proteins
Antibodies for PRAMEF22:
Assays for PRAMEF22: |
Protein
Domains/
Families
for PRAMEF22 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A3QJZ6 UniProtKB/Swiss-Prot: PRA22_HUMAN, A3QJZ6Similarity: Belongs to the PRAME familySimilarity: Contains 3 LRR (leucine-rich) repeats |
Gene Function
for PRAMEF22 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for PRAMEF22 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for PRAMEF22
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRAMEF22
|
Drugs & Compounds
for PRAMEF22 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for PRAMEF22
|
Transcripts
for PRAMEF22 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for PRAMEF22 gene: NM_001100631.1 Unigene Cluster for PRAMEF22: PRAME family member 22 Hs.712522 Unigene Representative Sequence: NM_001100631
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000376187(uc009vnq.1)
|
Expression
for PRAMEF22 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| PRAMEF22 expression in normal and diseased human tissues
1 Data from GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GATGGTCTGA
SOURCE GeneReport for Unigene cluster: Hs.712522
SABiosciences Custom PCR Arrays for PRAMEF22
|
Orthologs
for PRAMEF22 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for PRAMEF22 gene from 2 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
PRAMEF31 |
-- |
PRAME family member 3 |
97.85(n)
95.84(a) |
469822 XM_525207.2 XP_525207.2 |
rat
(Rattus norvegicus) |
RGD15624231 |
-- |
similar to DNA segment, Chr 5, ERATO Doi 577, expressed |
57.68(n)
42.76(a) |
501902 XM_577326.2 XP_577326.2 |
About this table Species with no ortholog for PRAMEF22
ENSEMBL Gene Tree for PRAMEF22 (if available) |
Paralogs
for PRAMEF22 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for PRAMEF22 gene
- PRAMEF31 2 PRAMEF192 PRAMEF102 PRAMEF202 PRAMEF232 LOC6453592 PRAMEF182 PRAMEF152
- PRAMEF122 PRAMEF212 PRAMEF22 PRAMEF92 PRAMEF132 PRAMEF142 PRAMEF72 PRAMEF82
- PRAMEF172 PRAMEF52 PRAMEF162 PRAMEF112 PRAMEF62 PRAMEF12
PRAMEF22 for paralogs About GeneDecksing
|
Genomic Variants
for PRAMEF22 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 1 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for PRAMEF22 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 26 variations for PRAMEF22
15/24 CNVs (see all 24): 2298 84057 67406 84056 73028 48105 73030 74339 30369 74340 84061 67405 6778 58330 84062
2 Indels: 84055 74338 |
Disorders & Mutations
for PRAMEF22 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for PRAMEF22 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for PRAMEF22 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
1 PubMed article for PRAMEF22 gene integrated from 7 sources:
(articles sorted by number of sources associating them with PRAMEF22)- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
|
External Searches for PRAMEF22 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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|
|
Genome Databases showing PRAMEF22 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PRAMEF22 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PRAMEF22 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PRAMEF22 gene:
Search GeneIP for patents involving PRAMEF22
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PRAMEF22 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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