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PROM2 Gene

protein-coding   GIFtS: 44

GC02P089982
prominin 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for PROM2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
prominin 21 2     prominin-22
Prominin-like protein 22 3     prominin-related protein2
PROML22 3     MGC1387142
hPROML22 3     PROM-23

External Ids:    HGNC: 206851   Entrez Gene: 1506962   Ensembl: ENSG000001550667   UniProtKB: Q8N2713   

Export aliases for PROM2 gene to outside databases

Previous GC identifers: GC02P094373 GC02P095408 GC02P095424 GC02P095362 GC02P095303 GC02P095942


Summaries
for PROM2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PROM2:
This gene encodes a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to
basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing
results in multiple transcript variants. (provided by RefSeq)


Genomic Views
for PROM2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PROM2 gene promoter:
         GR-alpha   JunD   AP-1   JunB   c-Fos   c-Jun   Fra-1   LCR-F1   AhR   Arnt   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for PROM2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.1   Ensembl cytogenetic band:  2q11.1   HGNC cytogenetic band: 2q11.1

PROM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PROM2 gene location

GeneLoc gene densities for chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P089982:  view genomic region     (about GC identifiers)

Start:
 89,967,276 bp from pter
End:
 89,984,207 bp from pter
Size:
 16,932 bases
Orientation:
 plus strand

1 alternative location:
Chr2+ 95,940,201-95,957,056     
RefSeq DNA sequence:
NC_000002.11  NT_022171.15  

Proteins
for PROM2 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: PROM2_HUMAN, Q8N271 (See protein sequence)
Recommended Name: Prominin-2 precursor  
Size: 834 amino acids; 91883 Da
Subunit: Binds cholesterol (By similarity)
Subcellular location: Apical cell membrane; Multi-pass membrane protein (By similarity). Basolateral cell membrane;
Multi-pass membrane protein (By similarity). Cell projection, microvillus membrane; Multi-pass membrane protein (By
similarity). Cell projection, cilium membrane; Multi-pass membrane protein (By similarity). Note=Colocalizes with
PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes
of epithelial cells (By similarity)
Sequence caution: Sequence=BAC03657.1; Type=Erroneous initiation;
Secondary accessions: A8K2V1 Q2HIX6 Q8NB84 Q8TAE2
Alternative splicing: 3 isoforms:  Q8N271-1   Q8N271-2   Q8N271-3   

Explore the universe of human proteins at neXtProt for PROM2: NX_Q8N271 

Post-translational modifications:

  • Glycosylated (By similarity)1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (3 alternative transcripts): 
    NP_001159449.1  NP_001159450.1  NP_653308.2  


    ENSEMBL proteins: 
    ENSP00000385716 ENSP00000402753 ENSP00000318270 ENSP00000318520 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: PROM2
    OriGene Protein Over-expression Lysate: PROM2
    GenScript Custom Purified and Recombinant Proteins Services for PROM2 
    Novus Biologicals Lysate for PROM2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5/7 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 7):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886 plasma membrane IEA--
    GO:0005929 cilium IEA--
    GO:0016021 integral to membrane IEA--
    GO:0016323 basolateral plasma membrane IEA--
    GO:0016324 apical plasma membrane IEA--
    About this table

    PROM2 for ontologies           About GeneDecksing



    Antibodies for PROM2: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    R&D Systems Antibodies for PROM2 (Prominin 2)
    OriGene Antibodies (see all 7): PROM2
    GenScript Custom Superior Antibodies Services for PROM2 
    Novus Biologicals Antibodies for PROM2
    Browse antibodies at Epitomics

    Assays for PROM2: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PROM2 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for PROM2 

    Protein Domains/
    Families
    for PROM2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PROM2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR008795 Prominin

    Graphical View of Domain Structure for InterPro Entry Q8N271

    ProtoNet protein and cluster: Q8N271

    UniProtKB/Swiss-Prot: PROM2_HUMAN, Q8N271
    Similarity: Belongs to the prominin family


    Gene Function
    for PROM2 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for PROM2
    Sigma-Aldrich shRNA for PROM2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): PROM2
    OriGene shRNA RFP (see all 3): PROM2
    OriGene basic RS shRNA (see all 3): PROM2
    OriGene siRNA (see all 3): PROM2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PROM2 
    miRNA:Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PROM2 
    1 SABiosciences Assays for microRNA that regulate PROM2:
    hsa-miR-942

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): PROM2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): PROM2
    OriGene untagged cDNA clones in CMV expression vector: PROM2
    OriGene 3'-UTR clone (see all 3): PROM2 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for PROM2 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for PROM2 

    1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004623 phospholipase A2 activity ----
    About this table

    PROM2 for ontologies           About GeneDecksing


    Pathways & Interactions
    for PROM2 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for PROM2 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PROM2

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644 phospholipid metabolic process ----
    GO:0016042 lipid catabolic process ----
    About this table

    PROM2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PROM2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PROM2


    Transcripts
    for PROM2 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for PROM2
    Sigma-Aldrich shRNA for PROM2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): PROM2
    OriGene shRNA RFP (see all 3): PROM2
    OriGene basic RS shRNA (see all 3): PROM2
    OriGene siRNA (see all 3): PROM2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PROM2 
    miRNA: Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PROM2 
    1 SABiosciences Assays for microRNA that regulate PROM2:
    hsa-miR-942
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): PROM2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): PROM2
    OriGene untagged cDNA clones in CMV expression vector: PROM2
    OriGene 3'-UTR Clone (see all 3): PROM2 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for PROM2 
    Primers: OriGene genome-wide validated SYBR primer pairs: PROM2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PROM2: PPH12567A

    REFSEQ mRNAs for PROM2 gene (3 alternative transcripts): 

    NM_001165977.1  NM_001165978.1  NM_144707.2  

    Additional cDNA sequence: 

    AF245303.1 AF245304.1 AK290366.1 AK313267.1 AY358377.1 BC025736.1 BC113877.1 BC114525.1 

    9 DOTS entries:

    DT.100754571  DT.75101526  DT.87015763  DT.100019216  DT.86838212  DT.95363439  DT.423392  DT.95122723 
    DT.91742528 

    24/49 AceView cDNA sequences (see all 49):

    AI762122 AA862642 AI281031 AK091175 BM768369 AL040582 AF245304 AA468976 
    BC025736 BM980816 AI346113 AX746828 AI702901 AK091408 NM_144707 AI792608 
    AI929095 AI928825 BP352952 AI932748 AW292801 AW513008 AI554512 CB146114 

    highest scoring ESTs for PROM2:

    AI733800 AF245303 AF245304 AI262848 AI346113 AI346501 AI702901 AI928825 AI932748 AI983995 

    Unigene Cluster for PROM2:

    Prominin 2
    Hs.469313  [show with all ESTs]
    Unigene Representative Sequence: NM_001165978


    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PROM2 (see all 8)

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^
    SP1:                                      -                                               -                                                                     
    SP2:                                      -                                               -                                                                     
    SP3:                                      -                                               -                                                                     
    SP4:                                                                                                                                                  -         
    SP5:                                -     -     -     -     -                                                                                                   

    ExUns: 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27
    SP1:                                            -     -               
    SP2:                                            -     -     -         
    SP3:                                                                  
    SP4:                                            -                     
    SP5:                                                                  

    About this scheme

    ECgene alternative splicing isoforms for PROM2
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000487138(uc002sul.2) ENST00000403131 ENST00000477767 ENST00000495540
    ENST00000463580 ENST00000431567(uc002suj.2) ENST00000317620(uc002sum.2)
    ENST00000478295 ENST00000497110 ENST00000317668(uc002suh.1 uc002sui.2 uc002suk.2)
    ENST00000462029

    Expression
    for PROM2 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    PROM2 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching PROM2 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    77516_r_at2, 3 U95-E 1 1.00 1.00 0.91 1.11 AI983995 0.80 1.00 0.91 1
    80590_at2, 3 U95-D 1 0.88 1.00 -0.38 0.91 AI929095 0.60 1.00 0.82 1
    82818_at2, 3 U95-E 1 0.75 1.00 0.95 1.00 AI733800 1.00 1.00 1.00 1
    239528_at2, 3 U133-B 1 0.82 1.00 -- -- BE513006 0.60 1.00 0.82 1
    1562378_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    1552797_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    239528_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    About this table

    PROM2 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    PROM2 gene expression
    PROM2 gene electronic northern expression
    PROM2 gene sage expression
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.469313

    UniProtKB/Swiss-Prot: PROM2_HUMAN, Q8N271
    Tissue specificity: Present in saliva within small membrane particles (at protein level). Expressed in kidney,
    prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal
    cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate
    cancer cell lines

    Primers: OriGene genome-wide validated SYBR primer pairs: PROM2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PROM2: PPH12567A
        SABiosciences Custom PCR Arrays for PROM2 


    Orthologs
    for PROM2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for PROM2 gene from 5/7 species (see all 7)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 PROM21   -- prominin 2 83.87(n)
    79.23(a)    		 611664  XM_849362.1  XP_854455.1 
    chimpanzee
    (Pan troglodytes)    		 PROM21   -- prominin 2 99.12(n)
    98.92(a)    		 738784  XM_001143498.1  XP_001143498.1 
    cow
    (Bos taurus)    		 PROM21   -- prominin 2 82.79(n)
    77.87(a)    		 520936  XM_599188.3  XP_599188.3 
    rat
    (Rattus norvegicus)    		 Prom21   -- prominin 2 78.72(n)
    73.36(a)    		 192211  NM_138857.1  NP_620212.1 
    mouse
    (Mus musculus)    		 Prom21 , 5 2 (62.04 cM)5
    		 prominin 21, 5 79.5(n)1
    73.5(a)1    		 1922121  NM_138750.11  NP_620089.11 
     AA7943755  AF1281135  (see all 13)
    About this table        Species with no ortholog for PROM2

    ENSEMBL Gene Tree for PROM2 (if available)

    Paralogs
    for PROM2 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for PROM2 gene
    PROM12  

    PROM2 for paralogs           About GeneDecksing



    Genomic Variants
    for PROM2 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/114 NCBI SNPs in PROM2 are shown (see all 114)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 2 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs10060211,2
    		C,F,A,H,95952641(-) GCCCCT/CGTGCT 3 -- int16Minor allele frequency- C:0.17MN NA EA WA 352
    rs11047751,2
    		C,F,H,95948987(+) CTGGCG/AGGAAG 3 -- int111Minor allele frequency- A:0.26NA WA 222
    rs22780671,2
    		C,F,H,95955680(-) GGACAA/CCAATA 3 -- int1 ut3117Minor allele frequency- N:0.00EA NA NS 2462
    rs23203391,2
    		C,F,A,H,95950045(+) caagaC/Acagcc 3 -- int17Minor allele frequency- A:0.19NA WA 16
    rs30761021,2
    		C95949559(+) attca-/TTCA  
                CACAG     		3 -- int11Minor allele frequency- TTCATTCA:0.50NA 2
    rs58327951,2
    		--95949548(+) ttcat-/TCAT  
                tcatt     		3 -- int10--------
    rs67392681,2
    		C,H,95951647(+) CACCCA/GTTGGC 3 -- int18Minor allele frequency- G:0.03NA WA 88
    rs75859141,2
    		C,F,A,H,95945568(+) TTAGTA/GACACC 3 -- int114Minor allele frequency- G:0.21NS EA NA WA 690
    rs75862291,2
    		C,F,A,H,95945830(+) GTGTGT/GCTGCC 3 -- int120Minor allele frequency- G:0.25NA NS EA WA 1092
    rs75964901,2
    		C,F,A,95954068(+) TCATCG/AGGGCT 3 -- int14Minor allele frequency- A:0.01NS EA 418
    About this table

    HapMap Linkage Disequilibrium images for PROM2 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PROM2: --

    Search QIAGEN SeqTarget long-range PCR primers for resequencing for PROM2 

    Disorders & Mutations
    for PROM2 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PROM2 for disorders           About GeneDecksing

    1 Novoseek disease relationship for PROM2 gene

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinal degeneration 61 1 12514187 (1)
    About this table


    Export disorders and mutations for PROM2 gene to outside databases

    Medical News
    for PROM2 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for PROM2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/17 PubMed articles for PROM2 gene, integrated from 7 sources (see all 17):
    (articles sorted by number of sources associating them with PROM2)
    1. Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins. (PubMed id 12514187)1, 2, 3, 7 Fargeas C.A.... Corbeil D. (2003)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder. (PubMed id 18536929)1, 7 Jaszai J....Corbeil D. (2008)
    5. Prominin-2 is a novel marker of distal tubules and co llecting ducts of the human and murine kidney. (PubMed id 20333396)1, 7 JA!szai J....Corbeil D. (2010)
    6. Differential expression of prominin-1 (CD133) and prominin-2 in major cephalic exocrine glands of adult mice. (PubMed id 17874118)2, 7 Jaszai J....Corbeil D. (2007)
    7. Effect of CD133/prominin-1 antisense oligodeoxynucleo tide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells an d U251 human glioma cells. (PubMed id 19724856)1, 7 Yao J....Wu G. (2009)
    8. An ultrastructural and immunohistochemical study of a combined submucosal granular cell tumor and lipoma of the colon showing a unique nodule-in-nodule structure: putative implication of CD34 or prominin-2-positive stromal cells in its histopathogenesis. (PubMed id 16673119)2 Mori T.... Yamazaki K. (2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell jun ction proteins as differentially expressed genes. (PubMed id 17145811)1 Rohan S....Chen Y.T. (2006)

    External Searches for PROM2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing PROM2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 150696 HGNC: 20685 AceView: PROM2 Ensembl:ENSG00000155066 euGenes: HUgn150696
    ECgene: PROM2 H-InvDB: PROM2

    Other Databases showing PROM2 gene

    (According to HUGE)
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    Specialized Databases showing PROM2 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    Intellectual Property
    for PROM2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    		Patent Information for PROM2 gene:
    Search GeneIP for patents involving PROM2

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    Products
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    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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     ELISAs and CLIAs for PROM2
           

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