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PRPH Gene

protein-coding   GIFtS: 60

GC12P046719
peripherin
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: NEF4)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
peripherin1 2
PRPH11 2 3
NEF42 3
neurofilament 4 (57kD)2
Neurofilament 43

External Ids:    HGNC: 94611   Entrez Gene: 56302   Ensembl: ENSG000001354067   UniProtKB: P412193   

Export aliases for PRPH gene to outside databases

Previous GC identifers: GC12M049560 GC12P049720 GC12P049405 GC12P047975 GC12P047973 GC12P049687


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PRPH:
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a
type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different
protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility
to amyotrophic lateral sclerosis. (provided by RefSeq)

UniProtKB/Swiss-Prot: PERI_HUMAN, P41219
Function: Class-III neuronal intermediate filament protein


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PRPH gene promoter:
         GCNF-1   GCNF-2   MyoD   NF-1   NRSF form 1   YY1   NRSF form 2   Pax-5   GR-alpha   GR-beta   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for PRPH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for PRPH 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12-q13   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q12-q13

PRPH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRPH gene location

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P046719:  view genomic region     (about GC identifiers)

Start:
46,719,777 bp from pter
End:
46,723,549 bp from pter
Size:
3,773 bases
Orientation:
plus strand

1 alternative location:
Chr12+ 49,687,485-49,692,465     
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: PERI_HUMAN, P41219 (See protein sequence)
Recommended Name: Peripherin  
Size: 470 amino acids; 53651 Da
Secondary accessions: Q8N577
Alternative splicing: 2 isoforms:  P41219-1   P41219-2   

Explore the universe of human proteins at neXtProt for PRPH: NX_P41219 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_006253.2  

    ENSEMBL proteins: 
    ENSP00000408897 ENSP00000257860 


    Human Recombinant Proteins 
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    OriGene Protein Over-expression Lysate: PRPH
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    Novus Biologicals Proteins for PRPH
    Novus Biologicals Lysates for PRPH
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    Browse ProSpec Recombinant Proteins

    5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005882 intermediate filament IEA--
    GO:0005883 neurofilament ----
    GO:0030424 axon ----
    GO:0044299 C-fiber ----
    GO:0045098 type III intermediate filament ----
    About this table

    PRPH for ontologies           About GeneDecksing



    Antibodies for PRPH: 
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    Uscn ELISAs and CLIAs for PRPH 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PRPH for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR018039 Intermediate_filament_CS
     IPR001664 IF
     IPR002957 Keratin_I
     IPR006821 Intermed_filament_DNA-bd
     IPR016044 F

    Graphical View of Domain Structure for InterPro Entry P41219

    ProtoNet protein and cluster: P41219

    1 Blocks protein family: IPB001664 Intermediate filament protein

    UniProtKB/Swiss-Prot: PERI_HUMAN, P41219
    Similarity: Belongs to the intermediate filament family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: PERI_HUMAN, P41219
    Function: Class-III neuronal intermediate filament protein

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
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    Sigma-Aldrich siRNA for PRPH
    Sigma-Aldrich shRNA Panels and shRNA for PRPH
    OriGene 29mer shRNA kits in GFP-retroviral vector: PRPH
    OriGene shRNA RFP: PRPH
    OriGene basic RS shRNA: PRPH
    OriGene siRNA: PRPH
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PRPH 
    miRNA:Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PRPH 
    Search SABiosciences for Assays for microRNAs that regulate PRPH

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: PRPH
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PRPH
    OriGene untagged cDNA clones in CMV expression vector: PRPH
    Browse 3'-UTR reporter clones for miRNA target validation 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: PRPH 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for PRPH 

    Genatlas biochemistry entry for PRPH:
    peripherin,neuronal,intermediate filament associated protein (IFAP,type III)

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198 structural molecule activity IEA--
    GO:0005515 protein binding ----
    About this table

    PRPH for ontologies           About GeneDecksing

    Animal Models: 1 MGI mutant phenotype (inferred from 1 allele(MGI details for Prph):

    nervous system

    PRPH for phenotypes           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    PRPH for pathways           About GeneDecksing

    1 Millipore Pathway for PRPH
        Cytoskeleton remodeling Neurofilaments

    1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  PRPH
        Amyotrophic Lateral Sclerosis Signaling

    1 Kegg Pathway  (Kegg details for PRPH):
        hsa05014 Amyotrophic lateral sclerosis (ALS)

        SABiosciences Custom Pathway-Focused PCR Arrays for PRPH 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for PRPH
        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PRPH

    1 Interacting protein for PRPH (P412192) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRT15P190122MINT-68372
    About this table

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045104 intermediate filament cytoskeleton organization ----
    About this table

    PRPH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PRPH


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA for PRPH
    Sigma-Aldrich shRNA Panels and shRNA for PRPH
    OriGene 29mer shRNA kits in GFP-retroviral vector: PRPH
    OriGene shRNA RFP: PRPH
    OriGene basic RS shRNA: PRPH
    OriGene siRNA: PRPH
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PRPH 
    miRNA: Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PRPH 
    Search SABiosciences for Assays for microRNAs that regulate PRPH
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: PRPH
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PRPH
    OriGene untagged cDNA clones in CMV expression vector: PRPH
    Browse 3'-UTR reporter clones for miRNA target validation 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: PRPH 
    Primers: OriGene genome-wide validated SYBR primer pairs: PRPH
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PRPH: PPH09060A

    REFSEQ mRNAs for PRPH gene: 

    NM_006262.3  

    Additional cDNA sequence: 

    AK125587.1 BC032703.1 CR591176.1 CR596536.1 CR598826.1 CR605251.1 CR605475.1 CR609048.1 
    CR609614.1 CR610243.1 CR615736.1 CR620795.1 CR624218.1 CR624274.1 

    6 DOTS entries:

    DT.410048  DT.100036479  DT.100778449  DT.100778456  DT.100832904  DT.100679296 

    24/111 AceView cDNA sequences (see all 111):

    AA417001 BQ128259 BQ722243 BG818891 AA427957 CR610243 BQ720548 BI963163 
    BU737271 CR620795 BQ898223 BQ069706 BC032703 CR609614 CR605251 NM_006262 
    CR591176 AI125438 BQ669826 BX282027 CR605475 CR624218 CR624274 CR598826 

    highest scoring ESTs for PRPH:

    AA417001 AA417186 AA427957 AA460760 AA975388 AI023248 AI125438 AI272354 AK125587 AL514681 

    Unigene Cluster for PRPH:

    Peripherin
    Hs.37044  [show with all ESTs]
    Unigene Representative Sequence: AK125587


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PRPH

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10
    SP1:                    -                 -                                                   
    SP2:                    -                 -                                                   
    SP3:                                      -                                                   
    SP4:                                                                                          

    About this scheme

    ECgene alternative splicing isoforms for PRPH
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000451891 ENST00000257860(uc001rtu.2)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    PRPH expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching PRPH gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    36298_at2, 3 U95-A 1 0.81 1.00 1.00 1.00 L14565 0.20 1.00 0.72 1
    213847_at2, 3 U133-A 1 0.82 1.00 -- -- NM_006262 0.60 1.00 0.82 1
    213847_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    About this table

    PRPH for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    PRPH gene expression
    PRPH gene electronic northern expression
    PRPH gene sage expression
    About these images

    CGAP SAGE TAG: TCCCGATAAG

    SOURCE GeneReport for Unigene cluster: Hs.37044

    Expression variation in blood from EXPOLDB for PRPH

    Primers: OriGene genome-wide validated SYBR primer pairs: PRPH
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for PRPH: PPH09060A
        SABiosciences Custom PCR Arrays for PRPH 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for PRPH gene from 5/7 species (see all 7)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    PRPH1   -- peripherin 93.43(n)
    97.22(a)
    477618  XM_534812.2  XP_534812.2 
    chimpanzee
    (Pan troglodytes)
    PRPH1   -- peripherin 99.93(n)
    100(a)
    451877  XM_509044.2  XP_509044.2 
    cow
    (Bos taurus)
    PRPH1   -- peripherin 92.57(n)
    96.54(a)
    510082  XM_587177.3  XP_587177.3 
    rat
    (Rattus norvegicus)
    Prph1   -- peripherin 90.65(n)
    96.57(a)
    24688  NM_012633.1  NP_036765.1 
    mouse
    (Mus musculus)
    Prph1 , 5 15 (55.72 cM)5
    peripherin1, 5 89.68(n)1
    95.91(a)1
    191321  NM_013639.11  NP_038667.11 
     AK1490215  BC0462915  (see all 8)
    About this table        Species with no ortholog for PRPH

    ENSEMBL Gene Tree for PRPH (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for PRPH gene
    DES2  NEFM2  VIM2  INA2  NEFH2  GFAP2  

    PRPH for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/41 NCBI SNPs in PRPH are shown (see all 41)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 12 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs20707601,2
    C,F,A,H,49690337(+) GGCGGT/CTTCTG 1 -- int19Minor allele frequency- C:0.10EA NA WA 1922
    rs20707611,2
    C,F,A,H,49690509(+) AAACCT/CGGCCT 1 -- int17Minor allele frequency- C:0.02EA NA WA 1866
    rs22367461,2
    C,F,49691567(+) GGCTCT/CTGCTC 1 -- int18Minor allele frequency- C:0.06EA NS NA WA 2036
    rs71375841,2
    H49692218(+) CCTCTC/ACCTCT 1 -- ut31 ese3 trp34Minor allele frequency- A:0.00NS EA 360
    rs73423181,2
    C,F,A,49692639(+) TTTGTC/TCCTCA 1 -- ng3114Minor allele frequency- T:0.15NS EA NA WA 1018
    rs73423841,2
    C,F,A,49692487(+) TTTGTT/GTCTGT 1 -- ng3110Minor allele frequency- G:0.19NS EA NA WA 674
    rs74868361,2
    C,F,A,49687378(+) CAAAGG/AGGGGA 1 -- ng51 trp37Minor allele frequency- A:0.03NS EA NA WA 542
    rs74883431,2
    C,A,49689597(+) CTCTTC/GCCTCC 1 -- int13Minor allele frequency- G:0.33NA WA 6
    rs118369761,2
    C,F,H,49691707(+) ACGCCT/CTCCCC 1 -- int1 trp32Minor allele frequency- C:0.19WA NA 54
    rs123691761,2
    C49689743(+) GAGAAG/TTGGGT 1 -- int10--------
    About this table

    HapMap Linkage Disequilibrium images for PRPH (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for PRPH
         1 CNV: 66218

    QIAGEN SeqTarget long-range PCR primers for resequencing PRPH 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PRPH for disorders           About GeneDecksing

    OMIM: 170710   disorders: 105400  

    Human Gene Mutation Database (HGMD): PRPH
    Genetic Association Database (GAD): PRPH
    Human Genome Epidemiology (HuGE) Navigator: PRPH (9 documents)

    Export disorders and mutations for PRPH gene to outside databases


    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/30 PubMed articles for PRPH gene, integrated from 7 sources (see all 30):
    (articles sorted by number of sources associating them with PRPH)
    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis. (PubMed id 15322088)1, 4 Gros-Louis F....Julien J.P. (2004)
    3. Charcot-Marie-Tooth disease and related neuropathies: mutation distribution and genotype-phenotype correlation. (PubMed id 11835375)1, 4 Boerkoel C.F.... Lupski J.R. (2002)
    4. The structure of the human peripherin gene (PRPH) and identification of potential regulatory elements. (PubMed id 7806235)1, 2 Foley J.... Parysek L.M. (1994)
    5. Chromosomal localisation of the mouse and human peripherin genes. (PubMed id 1378416)1, 3 Moncla A....Portier M.M. (1992)
    6. Distinct biochemical signatures characterize peripher in isoform expression in both traumatic neuronal injury and motor neuron diseas e. (PubMed id 20533992)1 McLean J....Robertson J. (2010)
    7. Protein kinase Cepsilon binds peripherin and induces its aggregation, which is accompanied by apoptosis of neuroblastoma cells. (PubMed id 18408015)1 Sunesson L....Larsson C. (2008)
    8. A comparative immunohistochemical analysis of small round cell tumors of childhood: utility of peripherin and alpha-internexin as markers for neuroblastomas. (PubMed id 18528283)1 Willoughby V....Donner L.R. (2008)
    9. An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology. (PubMed id 18287500)1 Xiao S....Robertson J. (2008)
    10. Transgenic mice expressing the Peripherin-EGFP genomic reporter display intrinsic peripheral nervous system fluorescence. (PubMed id 18709437)1 McLenachan S....Sarsero J.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5630 HGNC: 9461 AceView: PRPH Ensembl:ENSG00000135406 euGenes: HUgn5630
    ECgene: PRPH Kegg: 5630 H-InvDB: PRPH

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    Wikipedia http://en.wikipedia.org/wiki/Peripherin

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for PRPH gene:
    Search GeneIP for patents involving PRPH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

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    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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