Aliases &
Descriptions
for QRSL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 11 2 | | DKFZP564C12781 | | FLJ134471 2 | | glutamyl-tRNA(Gln) amidotransferase subunit A homolog2 | | FLJ121891 2 | | DKFZp564C12782 | | GatA1 2 | | OTTHUMP000000169222 | | FLJ109891 2 | | EC 6.3.5.-3 | | Glutaminyl-tRNA synthase-like protein 12 3 | | |
Export aliases for QRSL1 gene to outside databasesPrevious GC identifers: GC06P107077 GC06P107123 GC06P107185 |
Summaries
for QRSL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for QRSL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the QRSL1 gene promoter:
CREB GATA-1 GATA-2 GATA-3 YY1 Sox9 deltaCREB HNF-4alpha2 POU3F1 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for QRSL1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q21 Ensembl cytogenetic band: 6q21 HGNC cytogenetic band: 6q21QRSL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P104524: view genomic region
(about GC identifiers)
Start:
|
104,524,550 bp from pter |
End:
|
104,563,384 bp from pter |
Size:
|
38,835 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr6+ 107,077,453-107,116,292 |
RefSeq DNA sequence:- NC_000006.11 NT_025741.15
|
Proteins
for QRSL1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: QRSL1_HUMAN, Q9H0R6 (See
protein sequence)Recommended Name: Glutamyl-tRNA(Gln) amidotransferase subunit A homolog Size: 528 amino acids; 57460 Da
Sequence caution: Sequence=CAH72094.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5VWJ4 Q9HA60 Q9NV19Alternative splicing: 2 isoforms: Q9H0R6-1 Q9H0R6-2 Explore the universe of human proteins at neXtProt for QRSL1: NX_Q9H0R6
REFSEQ proteins: NP_060762.3
ENSEMBL proteins: ENSP00000358042 ENSP00000358040
Human Recombinant Proteins
Antibodies for QRSL1:
Assays for QRSL1: |
Protein
Domains/
Families
for QRSL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
QRSL1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H0R6ProtoNet protein and cluster: Q9H0R6 1 Blocks protein family: IPB000120 Amidase
UniProtKB/Swiss-Prot: QRSL1_HUMAN, Q9H0R6Similarity: Belongs to the amidase family |
Gene Function
for QRSL1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: QRSL1_HUMAN, Q9H0R6Catalytic activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamateEnzyme Number (IUBMB): EC 6.3.5.-
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- | | GO:0016874 | ligase activity |
IEA | -- | | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
IEA | -- |
About this table
QRSL1 for ontologies About GeneDecksing
|
Pathways & Interactions
for QRSL1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for QRSL1
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QRSL1
1 Interacting protein for QRSL1 (ENSP000003580423) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006412 | translation |
IEA | -- |
About this table
QRSL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for QRSL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for QRSL1
|
Transcripts
for QRSL1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for QRSL1 gene: NM_018292.4 Additional cDNA sequence: AK001851.1 AK022251.1 AK023509.1 AK055349.1 AK225262.1 AK225443.1 AK314694.1 AL136679.1 BC006084.1 BC014389.2 CR592831.1 CR598150.1 CR618052.1 11 DOTS entries: DT.443382 DT.100792867 DT.100670980 DT.95278114 DT.95278116 DT.95319561 DT.100717177 DT.100023319 DT.100806027 DT.91755953 DT.95278113 24/174 AceView cDNA sequences (see all 174): CR598150 AA961015 AA602557 BG036566 AW006165 AW074834 BX377832 R94566 BF223880 BM802270 BP365015 BX350644 AU121726 AI564684 CB161672 BX388846 AK023509 AW612708 AK022251 BG185173 BC014389 BF879325 N66117 BE891356
 highest scoring ESTs for QRSL1:AI416985 AI861854 AK001851 AK023509 AL136679 AU156313 AW976132 BC006084 BC014389 BG036566 Unigene Cluster for QRSL1: Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 Hs.406917 [show with all ESTs]Unigene Representative Sequence: NM_018292
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for QRSL1
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for QRSL1
3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369046(uc003prm.2) ENST00000467262 ENST00000369044(uc003prl.2)
|
Expression
for QRSL1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| QRSL1 expression in normal and diseased human tissues
1 / 2 / 3 10 probe-sets matching QRSL1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 90930_at2, 3
|
U95-E |
2 |
1.00 |
0.94 |
0.89 |
1.09 |
AI416985 |
1.00 |
1.00 |
1.00 |
1 |
| 78338_at2, 3
|
U95-E |
1 |
0.62 |
1.00 |
0.19 |
0.71 |
R01445 |
0.40 |
1.00 |
0.76 |
1 |
| 42742_at2, 3
|
U95-B |
1 |
0.62 |
1.00 |
0.78 |
0.93 |
AA769438 |
0.60 |
1.00 |
0.82 |
1 |
| 62794_at2, 3
|
U95-C |
1 |
0.50 |
1.00 |
0.46 |
1.29 |
AI861854 |
0.80 |
1.00 |
0.91 |
1 |
| 218949_s_at2, 3
|
U133-A |
3 |
1.00 |
0.91 |
-- |
-- |
NM_018292 |
0.60 |
1.00 |
0.82 |
1 |
| 241933_at2, 3
|
U133-B |
1 |
0.82 |
1.00 |
-- |
-- |
AA769438 |
0.60 |
1.00 |
0.82 |
1 |
| 233089_at2, 3
|
U133-B |
1 |
0.36 |
1.00 |
-- |
-- |
AK022251 |
0.60 |
1.00 |
0.82 |
1 |
| 218949_s_at2
|
U133Plus2 |
3 |
1.00 |
0.91 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 241933_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 233089_at2
|
U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
QRSL1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AGAGAAAATT
SOURCE GeneReport for Unigene cluster: Hs.406917
SABiosciences Custom PCR Arrays for QRSL1
|
Orthologs
for QRSL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for QRSL1 gene from 5/20 species (see all 20)
About this table Species with no ortholog for QRSL1
ENSEMBL Gene Tree for QRSL1 (if available) |
Paralogs
for QRSL1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for QRSL1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 6 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for QRSL1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for QRSL1
1 CNV: 51782 | | QIAGEN SeqTarget long-range PCR primers for resequencing QRSL1 |
|
Disorders & Mutations
for QRSL1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
QRSL1 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: QRSL1 (2 documents)
Export disorders and mutations for QRSL1 gene to outside databases
|
Medical News
for QRSL1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for QRSL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/16 PubMed articles for QRSL1 gene, integrated from 7 sources (see all 16):
(articles sorted by number of sources associating them with QRSL1)- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Biogenesis of glutaminyl-mt tRNAGln in human mitochon dria. (PubMed id 19805282)1 Nagao A....Suzuki T. (2009)
- Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PubMed id 18978678)1 Vieira A.R....Marazita M.L. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149)1 Suzuki Y.... Sugano S. (1997)
|
External Searches for QRSL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing QRSL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing QRSL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing QRSL1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for QRSL1 gene:
Search GeneIP for patents involving QRSL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for QRSL1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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 |  |  |  | |
| |  | Search Tocris compounds for QRSL1 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for QRSL1 |
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