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Aliases & Descriptionsfor RBM11 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase , and/or 9 Nature :405,311-319 and CroW21)About This Section Aliases & Descriptions RNA binding motif protein 111 2 RNA-binding motif protein 112 3 putative RNA-binding protein 112 putative gene, RNA binding motif protein 11 like9
Export aliases for RBM11 gene to outside databases Previous GC identifers: GC21P012252 GC21P014510 GC21P015588
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Summariesfor RBM11 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Gene Wiki entry for RBM11
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Genomic Viewsfor RBM11 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences , Whole Chromsome Sequence According to
Nature (Cited Here with Permission) :405,311-319 and CroW21)About This Section
GC21P000958:
GeneLoc
Nature :405,311-319
Start:
958,833 bp from pter
1,252,617 bp from centromere
End:
971,058 bp from pter
1,263,937 bp from centromere
Size:
12,226 bases
11,321 bases
Orientation:
plus strand
plus strand
1 alternative location : Chr 21+ 15,588,451-15,600,693
RefSeq DNA sequence: NC_000021.8 NT_011512.11
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Proteinsfor RBM11 gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: RBM11_HUMAN, P57052 (See
protein sequence )Recommended Name: Putative RNA-binding protein 11 Size : 281 amino acids; 32179 Da
Sequence caution : Sequence=AAH30196.2; Type=Erroneous initiation; Sequence=AAL82535.1; Type=Frameshift; Positions=33;Sequence=BAC03638.1; Type=Frameshift; Positions=33;
PDB structures from and Proteopedia : 2YWK (3D)
 
Secondary accessions : Q6YNC2 Q8NBA1 Q8NFF6Alternative splicing : 2 isoforms : P57052-1 P57052-2 Explore the universe of human proteins at neXtProt for RBM11: NX_P57052
REFSEQ proteins: NP_658983.3 ENSEMBL proteins: ENSP00000333170 ENSP00000383421 Human Recombinant Proteins Antibodies for RBM11: Assays for RBM11:
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Protein
Domains/ Familiesfor RBM11 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
RBM11 for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry P57052 ProtoNet protein and cluster: P57052
1 Blocks protein family : IPB000504 RNA-binding region RNP-1 (RNA recognition motif) UniProtKB/Swiss-Prot: RBM11_HUMAN, P57052 Similarity : Contains 1 RRM (RNA recognition motif) domain
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Gene Functionfor RBM11 gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section 3 Gene Ontology (GO) molecular function terms (GO ID links to tree view) :
About this table
RBM11 for ontologies About GeneDecksing
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Pathways & Interactionsfor RBM11 gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for RBM11 Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBM11 2 Interacting proteins for RBM11 (P57052 2 ) via UniProtKB, MINT, and/or STRING About this table
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Drugs & Compoundsfor RBM11 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for RBM11
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Transcriptsfor RBM11 gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for RBM11 gene: NM_144770.3
Additional cDNA sequence: AF519623.1 AK091331.1 AY077695.1 BC030196.1
5 DOTS entries : DT.95262633 DT.100745049 DT.91704104 DT.436113 DT.95237154
24 AceView cDNA sequences :
BC030196 AL596989 NM_144770 BX281687 BX104385 BQ186146 BX950891 AY077695 BX950892 BI913079 CB153254 AX746917 BI603848 AF519623 AK091331 BG706195 AL041993 BI753557 AA639269 N63517 D61628 N94835 BG541166 AA737090
highest scoring ESTs for RBM11 :AA639269 AA737090 AF519623 AK091331 AL041993 AY077695 BC030196 BG541166 BG706195 BI603848 Unigene Cluster for RBM11:
RNA binding motif protein 11 Hs.283828 [show with all ESTs ] Unigene Representative Sequence: BC030196 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for RBM11 ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d · 5e SP1 :           -               SP2 :           -     -           SP3 :     -       -     -           SP4 :     -   -     -     -           SP5 :     -                    
About this scheme ECgene alternative splicing isoforms for RBM11 7 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000330599 ENST00000461088 ENST00000495055 ENST00000475864 ENST00000468788 ENST00000400577 ENST00000468643 (uc002yjo.3 uc002yjn.3 uc002yjp.3 )
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Expression for RBM11 gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section RBM11 expression in normal and diseased human tissues 1 / 2 / 3
2 probe-sets matching RBM11 gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
232549_at2 , 3
U133-B
1
1.00
1.00
--
--
N94835
0.80
1.00
0.91
1
232549_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
About this table Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TTGCCTAGCA SOURCE GeneReport for Unigene cluster: Hs.283828 UniProtKB/Swiss-Prot: RBM11_HUMAN, P57052 Tissue specificity : Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland,spleen and kidney. Also expressed in fetal brain
SABiosciences Custom PCR Arrays for RBM11
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Orthologsfor RBM11 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for RBM11 gene from 5/8 species (see all 8 )
About this table Species with no ortholog for RBM11 ENSEMBL Gene Tree for RBM11 (if available)
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Paralogsfor RBM11 gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section Paralogs for RBM11 gene RBM7 2
RBM11 for paralogs About GeneDecksing
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Genomic Variantsfor RBM11 gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 21 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for RBM11 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for RBM11: --
QIAGEN SeqTarget long-range PCR primers for resequencing RBM11
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Disorders & Mutationsfor RBM11 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Medical Newsfor RBM11 gene (Possibly Related Articles in
Doctor's Guide )
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Publicationsfor RBM11 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 10 PubMed articles for RBM11 gene integrated from 7 sources : (articles sorted by number of sources associating them with RBM11) Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis. (PubMed id 12036298) 1 , 2 , 3 Gardiner K....Davisson M. (2002) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms. (PubMed id 12909339) 1 , 2 Brun M.-E.... De Sario A. (2003) The DNA sequence of human chromosome 21. (PubMed id 10830953) 1 , 2 Hattori M....Yaspo M.L. (2000) Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791) 1 Wang A.G....Kim N.S. (2006) A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569) 1 Lim J.... Zoghbi H.Y. (2006) Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514) 1 Rual J.F....Vidal M. (2005) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548) 1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for RBM11 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RBM11 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing RBM11 gene
(According to HUGE )
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Specialized Databases showing RBM11 gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for RBM11 gene: Search GeneIP for patents involving RBM11 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor RBM11 gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for RBM11
ELISAs and CLIAs for RBM11
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