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RNF180 Gene

protein-coding   GIFtS: 42

GC05P060416
ring finger protein 180
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
ring finger protein 1801 2 3
E3 ubiquitin-protein ligase RNF1802
MGC1203282
MGC1203262
OTTHUMP000002218192
EC 6.3.2.-3

External Ids:    HGNC: 277521   Entrez Gene: 2856712   Ensembl: ENSG000001641977   UniProtKB: Q86T963   

Export aliases for RNF180 gene to outside databases

Previous GC identifer: GC05P063498


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RN180_HUMAN, Q86T96
Function: E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of
ZIC2 (By similarity)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for RNF180
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for RNF180

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for RNF180 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q12.3   Ensembl cytogenetic band:  5q12.3   HGNC cytogenetic band: 5q12.3

RNF180 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF180 gene location

GeneLoc gene densities for chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P060416:  view genomic region     (about GC identifiers)

Start:
60,416,366 bp from pter
End:
60,622,951 bp from pter
Size:
206,586 bases
Orientation:
plus strand

1 alternative location:
Chr5+ 63,461,671-63,668,696     
RefSeq DNA sequence:
NC_000005.9  NT_006713.15  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: RN180_HUMAN, Q86T96 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF180  
Size: 592 amino acids; 68254 Da
Subunit: Interacts with ZIC2 (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope (By similarity)
Sequence caution: Sequence=CAD89939.1; Type=Erroneous initiation;
Secondary accessions: Q0JSU3 Q495A8 Q8NBD1
Alternative splicing: 3 isoforms:  Q86T96-1   Q86T96-2   Q86T96-3   

Explore the universe of human proteins at neXtProt for RNF180: NX_Q86T96 

REFSEQ proteins (2 alternative transcripts): 
NP_001107033.1  NP_848627.1  


ENSEMBL proteins: 
ENSP00000296615 ENSP00000370471 ENSP00000373752 ENSP00000426884 


Human Recombinant Proteins 
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Novus Biologicals Proteins for RNF180
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

5/6 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 6):

GO IDQualified GO termEvidencePubMed IDs
GO:0005634 nucleus IEA--
GO:0005635 nuclear envelope IEA--
GO:0005783 endoplasmic reticulum IEA--
GO:0016020 membrane IEA--
GO:0016021 integral to membrane IEA--
About this table

RNF180 for ontologies           About GeneDecksing



Antibodies for RNF180: 
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Novus Biologicals Antibodies for RNF180
Browse antibodies at Epitomics

Assays for RNF180: 
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Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for RNF180 
Browse Enzo Life Sciences for kits & assays
Browse ELISAs and CLIAs at Uscn 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RNF180 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR017907 Znf_RING_CS
 IPR001841 Znf_RING
 IPR018957 Znf_C3HC4_RING-type
 IPR013083 Znf_RING/FYVE/PHD

Graphical View of Domain Structure for InterPro Entry Q86T96

ProtoNet protein and cluster: Q86T96

1 Blocks protein family: IPB001841 Zn-finger

UniProtKB/Swiss-Prot: RN180_HUMAN, Q86T96
Domain: The RING-type zinc finger domain mediates polyubiquitination of the interacting protein
Similarity: Contains 1 RING-type zinc finger


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: RN180_HUMAN, Q86T96
Function: E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of
ZIC2 (By similarity)
Enzyme Number (IUBMB): EC 6.3.2.- 

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for RNF180
Sigma-Aldrich shRNA for RNF180
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): RNF180
OriGene shRNA RFP (see all 3): RNF180
OriGene basic RS shRNA (see all 3): RNF180
OriGene siRNA (see all 2): RNF180
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of RNF180 
miRNA:Sigma-Aldrich microRNA Mimics for RNF180
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of RNF180 
8/17 SABiosciences Assays for microRNAs that regulate RNF180 (see all 17):
hsa-miR-520e hsa-miR-25 hsa-miR-633 hsa-miR-372 hsa-miR-330-3p hsa-miR-520d-3p hsa-miR-33b hsa-miR-302b

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: RNF180
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): RNF180
OriGene untagged cDNA clones in CMV expression vector (see all 3): RNF180
OriGene 3'-UTR clone (see all 2): RNF180 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for RNF180 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for RNF180 

5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6):

GO IDQualified GO termEvidencePubMed IDs
GO:0004842 ubiquitin-protein ligase activity IEA--
GO:0005515 protein binding IEA--
GO:0008270 zinc ion binding IEA--
GO:0016874 ligase activity IEA--
GO:0031624 ubiquitin conjugating enzyme binding IEA--
About this table

RNF180 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

UniProtKB/Swiss-Prot: RN180_HUMAN, Q86T96
Pathway: Protein modification; protein ubiquitination

    SABiosciences Custom Pathway-Focused PCR Arrays for RNF180 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF180

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA--
About this table

RNF180 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RNF180


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for RNF180
Sigma-Aldrich shRNA for RNF180
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): RNF180
OriGene shRNA RFP (see all 3): RNF180
OriGene basic RS shRNA (see all 3): RNF180
OriGene siRNA (see all 2): RNF180
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of RNF180 
miRNA: Sigma-Aldrich microRNA Mimics for RNF180
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of RNF180 
8/17 SABiosciences Assays for microRNAs that regulate RNF180 (see all 17):
hsa-miR-520e hsa-miR-25 hsa-miR-633 hsa-miR-372 hsa-miR-330-3p hsa-miR-520d-3p hsa-miR-33b hsa-miR-302b
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: RNF180
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): RNF180
OriGene untagged cDNA clones in CMV expression vector (see all 3): RNF180
OriGene 3'-UTR Clone (see all 2): RNF180 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for RNF180 
Primers: OriGene genome-wide validated SYBR primer pairs: RNF180
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for RNF180: PPH23039A

REFSEQ mRNAs for RNF180 gene (2 alternative transcripts): 

NM_001113561.1  NM_178532.3  

Additional cDNA sequence: 

AK090756.1 AL832580.2 BC101277.2 BC101278.2 BC101279.1 BC101397.2 

3 DOTS entries:

DT.308885  DT.100020671  DT.307726 

24/34 AceView cDNA sequences (see all 34):

BX113020 BM728889 BE672684 BI006702 BM718923 CB999963 AX746601 BE218282 
BE222198 BF115015 AI273646 AA035198 AI216189 AL832580 AK090756 AI167804 
AI431828 BF433928 BV192623 AI521986 CB267379 NM_178532 AA040069 CD356815 

highest scoring ESTs for RNF180:

H05502 AA035198 AK090756 AL832580 BG218201 BI006702 BM728889 AA040069 AI167804 AI216189 

Unigene Cluster for RNF180:

Ring finger protein 180
Hs.657843  [show with all ESTs]
Unigene Representative Sequence: NM_001113561


GeneLoc Exon Structure

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000296615(uc003jth.3) ENST00000381081(uc010iws.2) ENST00000389100(uc003jti.2)
ENST00000504296

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

RNF180 expression in normal and diseased human tissues

1  / 2  / 3

8 probe-sets matching RNF180 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
58752_at2, 3 U95-B 1 0.44 1.00 0.55 0.34 AA040069 0.60 1.00 0.82 1
50617_s_at2, 3 U95-B 1 0.44 1.00 0.95 1.38 AI431828 0.60 1.00 0.82 1
61743_at2, 3 U95-C 1 0.38 1.00 0.88 1.18 H05502 1.00 1.00 1.00 1
50620_r_at2, 3 U95-B 1 0.31 1.00 0.90 0.47 AI431828 0.60 1.00 0.82 1
242033_at2, 3 U133-B 1 0.64 1.00 -- -- BE672684 0.60 1.00 0.82 1
236644_at2, 3 U133-B 1 0.27 1.00 -- -- BF433928 0.60 1.00 0.82 1
242033_at2 U133Plus2 1 0.64 1.00 -- -- -- -- -- -- --
236644_at2 U133Plus2 1 0.27 1.00 -- -- -- -- -- -- --
About this table

RNF180 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
RNF180 gene expression
RNF180 gene electronic northern expression
RNF180 gene sage expression
About these images

CGAP SAGE TAG: AGGAATAAAA

SOURCE GeneReport for Unigene cluster: Hs.657843
Primers: OriGene genome-wide validated SYBR primer pairs: RNF180
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for RNF180: PPH23039A
    SABiosciences Custom PCR Arrays for RNF180 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for RNF180 gene from 5 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
RNF1801   -- ring finger protein 180 89.84(n)
83.63(a)
487231  XM_855650.1  XP_860743.1 
chimpanzee
(Pan troglodytes)
RNF1801   -- ring finger protein 180 98.78(n)
98.53(a)
471823  XM_527201.2  XP_527201.2 
cow
(Bos taurus)
RNF1801   -- ring finger protein 180 89.24(n)
83.37(a)
540391  XM_593727.3  XP_593727.3 
mouse
(Mus musculus)
Rnf1801 , 5 13 (56.92 cM)5
ring finger protein 1801, 5 83.25(n)1
77.7(a)1
718161  NM_027934.21  NP_082210.11 
 AK0139415  AK0322595  (see all 14)
chicken
(Gallus gallus)
RNF1801   -- ring finger protein 180 57.35(n)
40.99(a)
431582  XM_429137.2  XP_429137.2 
About this table        Species with no ortholog for RNF180

ENSEMBL Gene Tree for RNF180 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
  --

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/1356 NCBI SNPs in RNF180 are shown (see all 1356)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 5 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs3566361,2
C,63461976(+) GCGGCG/CGCGGC 1 -- int12Minor allele frequency- C:0.25NA 4
rs9519601,2
C,F,O,A,63473068(-) GGGAAT/AGTGTA 1 -- int110Minor allele frequency- A:0.35NS EA NA WA 516
rs9654911,2
H63605779(+) AACTTT/GGACTA 1 -- int14Minor allele frequency- G:0.00NS EA 418
rs9657081,2
C,F,A,H,63548381(+) caaggC/Tttttt 1 -- int112Minor allele frequency- N:0.02NS EA NA WA 842
rs9709901,2
H63525924(+) ATTTAG/AGTTGT 1 -- int15Minor allele frequency- A:0.00MN NS EA 600
rs9709911,2
H63526134(+) ctgtaG/Agtaag 1 -- int14Minor allele frequency- A:0.00NS EA 418
rs9766921,2
C,F,A,63629739(+) TAGCCG/AATTAA 1 -- int111Minor allele frequency- A:0.32NS EA NA WA 638
rs10561081,2
63668017(+) TTTTTA/TAAAAA 1 -- ut310--------
rs11122461,2
C,F,H,63600018(-) gctctC/Ttggtg 1 -- int110Minor allele frequency- T:0.42NS EA NA WA 584
rs11552861,2
C,F,A,H,63574428(+) GAGATA/GATAAT 1 -- int110Minor allele frequency- G:0.43NS EA NA WA 630
About this table

HapMap Linkage Disequilibrium images for RNF180 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RNF180
     2 CNVs: 99160 99159

QIAGEN SeqTarget long-range PCR primers for resequencing RNF180 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RNF180 for disorders           About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: RNF180 (1 document)

Export disorders and mutations for RNF180 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/11 PubMed articles for RNF180 gene, integrated from 7 sources (see all 11):
(articles sorted by number of sources associating them with RNF180)
  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
  4. Rines/RNF180, a novel RING finger gene-encoded produc t, is a membrane-bound ubiquitin ligase. (PubMed id 18363970)1 Ogawa M....Aruga J. (2008)
  5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
  6. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
  7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  8. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  10. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1 Wiemann S.... Poustka A. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 285671 HGNC: 27752 AceView: LOC285671 Ensembl:ENSG00000164197 euGenes: HUgn285671
ECgene: RNF180 H-InvDB: RNF180

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for RNF180 gene:
Search GeneIP for patents involving RNF180

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
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 SeqTarget long-range PCR primers for resequencing RNF180
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for RNF180
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of RNF180
 GenScript Custom Purified and Recombinant Proteins Services for RNF180 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for RNF180
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