Aliases &
Descriptions
for RPL32 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| ribosomal protein L321 2 | | 60S ribosomal protein L322 | | OTTHUMP000002079062 | | OTTHUMP000002079072 | | OTTHUMP000002079042 | | M5 |
Export aliases for RPL32 gene to outside databasesPrevious GC identifers: GC03M012806 GC03M012869 GC03M012852 GC03M012853 |
Summaries
for RPL32 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RPL32:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This geneencodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family ofribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it isbelieved to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the sameprotein have been observed for this gene. (provided by RefSeq)
Gene Wiki entry for RPL32 |
Genomic Views
for RPL32 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RPL32 gene promoter:
TBP TFIID AREB6 NRSF form 1 NRSF form 2 CUTL1 COUP-TF1 POU3F2 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b)
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPL32
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for RPL32  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p25-p24 Ensembl cytogenetic band: 3p25.2 HGNC cytogenetic band: 3q13.3-q21RPL32 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M012810: view genomic region
(about GC identifiers)
Start:
|
12,810,357 bp from pter |
End:
|
12,816,994 bp from pter |
Size:
|
6,638 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr3- 12,875,984-12,883,087 |
RefSeq DNA sequence:- NC_000003.11 NT_022517.18
|
Proteins
for RPL32 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: RL32_HUMAN, P62910 (See
protein sequence)Recommended Name: 60S ribosomal protein L32 Size: 135 amino acids; 15860 Da
Secondary accessions: B2R4Q3 P02433Explore the universe of human proteins at neXtProt for RPL32: NX_P62910
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (3 alternative transcripts):
NP_000985.1 NP_001007074.1 NP_001007075.1
ENSEMBL proteins: ENSP00000380158 ENSP00000339064 ENSP00000416429 ENSP00000413742 ENSP00000412393 ENSP00000380156 ENSP00000388674
Human Recombinant Proteins
4 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
RPL32 for ontologies About GeneDecksing
Antibodies for RPL32:
Assays for RPL32: |
Protein
Domains/
Families
for RPL32 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPL32 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62910ProtoNet protein and cluster: P62910 UniProtKB/Swiss-Prot: RL32_HUMAN, P62910Similarity: Belongs to the ribosomal protein L32e family |
Gene Function
for RPL32 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
Genatlas biochemistry entry for RPL32:60S ribosomal protein L32,15kDa2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
RPL32 for ontologies About GeneDecksing
|
Pathways & Interactions
for RPL32 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
RPL32 for pathways About GeneDecksing
1  Kegg Pathway (Kegg details for RPL32):
SABiosciences Pathway-Focused PCR Array including RPL32: PAHS-032A
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPL32
5/110 Interacting proteins for RPL32 (ENSP000003390643 P629101, 2) via UniProtKB, MINT, and/or STRING (see all 110)About this table
5/9 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 9): About this table
RPL32 for ontologies About GeneDecksing
|
Drugs & Compounds
for RPL32 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
RPL32 for compounds About GeneDecksing
 Browse Tocris compounds for RPL32
1  Novoseek chemical compound relationship for RPL32 gene
About this table
|
Transcripts
for RPL32 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for RPL32 gene (3 alternative transcripts): NM_000994.3 NM_001007073.1 NM_001007074.1 Additional cDNA sequence: AJ609430.1 AK311909.1 BC011514.1 BC070209.1 CR591453.1 CR596681.1 CR596797.1 CR596982.1 CR600427.1 CR600919.1 CR604700.1 CR605770.1 CR608027.1 CR614770.1 CR616653.1 CR620958.1 CR625712.1 NR_002582.1 X03342.1 24/64 DOTS entries (see all 64): DT.100704457 DT.100688774 DT.120880950 DT.92466266 DT.97862741 DT.92466249 DT.100057506 DT.100704463 DT.100059768 DT.92466260 DT.100052296 DT.95222740 DT.120880879 DT.120880904 DT.100704462 DT.91644924 DT.100704459 DT.92407123 DT.120881024 DT.120881007 DT.92402080 DT.100704471 DT.101955665 DT.99945073 24/1673 AceView cDNA sequences (see all 1673): AA336777 F28768 BM887881 CR605770 AA531078 BE907245 BX385361 BC011514 BU621158 AI074227 BM792745 AV745449 BI086899 AA304553 BF035775 BQ226074 BQ217969 CR604700 F29344 AI718102 T27781 AA410798 BX342104 BM014119
 highest scoring ESTs for RPL32:X03342 AA303944 AA308510 AA317568 AA339679 AA360247 AA384379 AA535297 AA649104 AI557072 Unigene Cluster for RPL32: Ribosomal protein L32 Hs.265174 [show with all ESTs]Unigene Representative Sequence: CR596982
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for RPL32
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for RPL32
8 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396957(uc003bxl.2 uc003bxn.2) ENST00000273223 ENST00000452606
ENST00000429711(uc003bxm.2) ENST00000434963 ENST00000457131 ENST00000396953
ENST00000435983
|
Expression
for RPL32 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| RPL32 expression in normal and diseased human tissues
1 / 2 / 3 4 probe-sets matching RPL32 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 32276_at2, 3
|
U95-A |
7 |
1.00 |
0.60 |
0.26 |
1.44 |
X03342 |
1.00 |
0.90 |
0.95 |
1 |
| 89800_at2, 3
|
U95-E |
1 |
0.81 |
1.00 |
0.94 |
0.58 |
AI123843 |
0.60 |
0.75 |
0.68 |
1 |
| 200674_s_at2, 3
|
U133-A |
13 |
1.00 |
0.46 |
-- |
-- |
NM_000994 |
0.60 |
1.00 |
0.82 |
1 |
| 200674_s_at2
|
U133Plus2 |
13 |
1.00 |
0.46 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
RPL32 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TGCACGTTTT
SOURCE GeneReport for Unigene cluster: Hs.265174
SABiosciences Expression via Pathway-Focused PCR Array including RPL32: PAHS-032A
|
Orthologs
for RPL32 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RPL32 gene from 5/23 species (see all 23)
About this table Species with no ortholog for RPL32
ENSEMBL Gene Tree for RPL32 (if available) |
Paralogs
for RPL32 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for RPL32 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 3 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for RPL32 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RPL32
1 CNV: 8414
1 Inversion: 37239 |
Disorders & Mutations
for RPL32 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPL32 for disorders About GeneDecksing
OMIM: 611839
Export disorders and mutations for RPL32 gene to outside databases
|
Medical News
for RPL32 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for RPL32 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/28 PubMed articles for RPL32 gene, integrated from 7 sources (see all 28):
(articles sorted by number of sources associating them with RPL32)- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
- Assignment of the L32 ribosomal protein gene (RPL32) to human chromosome 3q13.3-->q21 by in situ hybridization. (PubMed id 9284913)1, 3 Vorobieva N.V....Graphodatsky A.S. (1997)
- A processed pseudogene in an intron of the HLA-DP beta 1 chain gene is a member of the ribosomal protein L32 gene family. (PubMed id 3866218)1, 2 Young J.A.T. and Trowsdale J. (1985)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
- Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters. (PubMed id 17054774)1 Baumbusch L.O....Borresen-Dale A.L. (2006)
- The molecular mechanics of eukaryotic translation. (PubMed id 15189156)1 Kapp L.D. and Lorsch J.R. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. (PubMed id 14567916)1 Mazumder B....Fox P.L. (2003)
|
External Searches for RPL32 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RPL32 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RPL32 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPL32 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RPL32 gene:
Search GeneIP for patents involving RPL32
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RPL32 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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 |  |  |  | |
| |  | Search Tocris compounds for RPL32 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for RPL32 |
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