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Aliases & Descriptionsfor RSAD1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions radical S-adenosyl methionine domain containing 11 2 FLJ111641 2 Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD12 3 FLJ209752 radical S-adenosyl methionine domain-containing protein 1, mitochondrial2 EC 1.3.99.-3
Export aliases for RSAD1 gene to outside databases Previous GC identifers: GC17P045912 GC17P048556
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Summariesfor RSAD1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: RSAD1_HUMAN, Q9HA92 Function : May be involved in porphyrin cofactor biosynthesis (By similarity)
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Genomic Viewsfor RSAD1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RSAD1 gene promoter: FOXO1a COUP-TF1 HNF-4alpha2 FOXO4 FAC1 PPAR-gamma2 PPAR-gamma1 FOXO3b FOXO3a GR-alpha Other transcription factors Search SABiosciences Chromatin IP Primers for RSAD1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for RSAD1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17q21.33 Ensembl cytogenetic band: 17q21.33 HGNC cytogenetic band: 17q21.33 RSAD1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17P043924: view genomic region
(about GC identifiers )
Start:
43,924,104 bp from pter
End:
43,931,255 bp from pter
Size:
7,152 bases
Orientation:
plus strand
1 alternative location : Chr 17+ 48,556,161-48,563,336
RefSeq DNA sequence: NC_000017.10 NT_010783.15
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Proteinsfor RSAD1 gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: RSAD1_HUMAN, Q9HA92 (See
protein sequence )Recommended Name: Radical S-adenosyl methionine domain-containing protein 1, mitochondrial precursor Size : 442 amino acids; 48714 Da
Cofactor : Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeableS-adenosyl-L-methionine (Potential)
Subcellular location : Mitochondrion (Potential)
Secondary accessions : Q53HV8 Q86VC4 Q9BRY7 Q9NUS7Explore the universe of human proteins at neXtProt for RSAD1: NX_Q9HA92
REFSEQ proteins: NP_060816.1 ENSEMBL proteins: ENSP00000258955 ENSP00000424558 ENSP00000425372 ENSP00000430352 ENSP00000422893 ENSP00000395071 Human Recombinant Proteins 2 Gene Ontology (GO) cellular component terms (GO ID links to tree view) :
About this table
RSAD1 for ontologies About GeneDecksing Antibodies for RSAD1: Assays for RSAD1:
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Protein
Domains/ Familiesfor RSAD1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
RSAD1 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9HA92 ProtoNet protein and cluster: Q9HA92
1 Blocks protein family : IPB006638 Elongator protein 3/MiaB/NifB UniProtKB/Swiss-Prot: RSAD1_HUMAN, Q9HA92 Similarity : Belongs to the anaerobic coproporphyrinogen-III oxidase family
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Gene Functionfor RSAD1 gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section UniProtKB/Swiss-Prot: RSAD1_HUMAN, Q9HA92 Function : May be involved in porphyrin cofactor biosynthesis (By similarity)Enzyme Number (IUBMB): EC 1.3.99.-
5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6 ):
About this table
RSAD1 for ontologies About GeneDecksing
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Pathways & Interactionsfor RSAD1 gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for RSAD1 Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RSAD1 2 Gene Ontology (GO) biological process terms (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006779 porphyrin biosynthetic process
IEA -- GO:0055114 oxidation-reduction process
IEA --
About this table
RSAD1 for ontologies About GeneDecksing
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Drugs & Compoundsfor RSAD1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for RSAD1
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Transcriptsfor RSAD1 gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for RSAD1 gene: NM_018346.1
Additional cDNA sequence: AK002026.1 AK022105.1 AK024628.1 AK222472.1 AK293814.1 AK297655.1 BC005854.2 BC050538.1 CR621437.1
14 DOTS entries : DT.442467 DT.100792965 DT.100792967 DT.402970 DT.100792963 DT.120971878 DT.75160905 DT.95273663
DT.120971901 DT.95087348 DT.100659056 DT.100792962 DT.120971896 DT.86855383 24/233 AceView cDNA sequences (see all 233 ):
AV653956 CD513517 BM454672 BM713111 BM677032 AK024628 BM916831 CB140338 BF805228 BI822661 BC050538 BQ066444 NM_018346 BQ065969 BE671496 BM701378 BF805231 BQ012945 BQ064844 CR621437 BQ059574 AA437121 BM561668 BQ437032
highest scoring ESTs for RSAD1 :N94998 AA055526 AA055527 AA171610 AA171769 AA302984 AA303758 AA350538 AA351438 AA361061 Unigene Cluster for RSAD1:
Radical S-adenosyl methionine domain containing 1 Hs.8033 [show with all ESTs ] Unigene Representative Sequence: AK002026 GeneLoc Exon Structure 10 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000258955 (uc002iqw.1 uc010wmq.1 ) ENST00000443328 (uc010wmp.1 )ENST00000515221 ENST00000504284 ENST00000510554 ENST00000506211 ENST00000509398 ENST00000513650 ENST00000511005 ENST00000451010
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Expression for RSAD1 gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section RSAD1 expression in normal and diseased human tissues 1 / 2 / 3
3 probe-sets matching RSAD1 gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
55024_at2 , 3
U95-B
1
1.00
1.00
1.00
1.00
N94998
1.00
1.00
1.00
1
218307_at2 , 3
U133-A
1
1.00
1.00
--
--
NM_018346
0.60
1.00
0.82
1
218307_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
About this table
RSAD1 for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GTTCTATTTA SOURCE GeneReport for Unigene cluster: Hs.8033 SABiosciences Custom PCR Arrays for RSAD1
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Orthologsfor RSAD1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for RSAD1 gene from 5/6 species (see all 6 )
About this table Species with no ortholog for RSAD1 ENSEMBL Gene Tree for RSAD1 (if available)
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Paralogsfor RSAD1 gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section --
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Genomic Variantsfor RSAD1 gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 17 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for RSAD1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for RSAD1: --
QIAGEN SeqTarget long-range PCR primers for resequencing RSAD1
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Disorders & Mutationsfor RSAD1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
RSAD1 for disorders About GeneDecksing Human Genome Epidemiology (HuGE) Navigator: RSAD1 (1 document)Export disorders and mutations for RSAD1 gene to outside databases
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Medical Newsfor RSAD1 gene (Possibly Related Articles in
Doctor's Guide )
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Publicationsfor RSAD1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 6 PubMed articles for RSAD1 gene integrated from 7 sources : (articles sorted by number of sources associating them with RSAD1) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 , 3 Strausberg R.L....Marra M.A. (2002) Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624) 1 Hendrickson S.L....O'Brien S.J. (2010) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149) 1 Suzuki Y.... Sugano S. (1997) Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298) 1 Maruyama K. and Sugano S. (1994)
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External Searches for RSAD1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RSAD1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing RSAD1 gene
(According to HUGE )
About This Section --
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Specialized Databases showing RSAD1 gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for RSAD1 gene: Search GeneIP for patents involving RSAD1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor RSAD1 gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for RSAD1
ELISAs and CLIAs for RSAD1
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