Aliases &
Descriptions
for RSBN1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| round spermatid basic protein 11 2 | | ROSBIN1 2 | | FLJ112201 | | DKFZp781E211502 | | RP11-324J2.12 | | OTTHUMP000000137232 |
Export aliases for RSBN1 gene to outside databasesPrevious GC identifers: GC01M114019 GC01M114105 GC01M114304 |
Summaries
for RSBN1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RSBN1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RSBN1 gene promoter:
c-Myb Egr-1 TGIF MIF-1 p300 GCNF-2 GCNF-1 Hlf FOXJ2 (long isoform) CREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for RSBN1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for RSBN1  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13.2 Ensembl cytogenetic band: 1p13.2 HGNC cytogenetic band: 1p13.1RSBN1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M112162: view genomic region
(about GC identifiers)
Start:
|
112,162,586 bp from pter |
End:
|
112,213,193 bp from pter |
Size:
|
50,608 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr1- 114,304,454-114,355,070 |
RefSeq DNA sequence:- NC_000001.10 NT_032977.9
|
Proteins
for RSBN1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: RSBN1_HUMAN, Q5VWQ0 (See
protein sequence)Recommended Name: Round spermatid basic protein 1 Size: 802 amino acids; 90072 Da
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=AAH26155.1; Type=Erroneous initiation; Sequence=BAA92075.1; Type=Erroneous initiation;Sequence=BAB13974.1; Type=Erroneous initiation; Sequence=CAH10493.1; Type=Erroneous initiation; Note=TranslationN-terminally extended; Sequence=CAH10493.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;Sequence=CAH72507.1; Type=Erroneous initiation; Sequence=CAI19067.1; Type=Erroneous initiation;
Secondary accessions: A8K937 Q6AI21 Q8TC33 Q9HA80 Q9NUP6Alternative splicing: 2 isoforms: Q5VWQ0-1 Q5VWQ0-4 Explore the universe of human proteins at neXtProt for RSBN1: NX_Q5VWQ0
Post-translational modifications:
Phosphorylated by PKA (By similarity)1
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_060834.2
ENSEMBL proteins: ENSP00000358594 ENSP00000261441 ENSP00000406185
Human Recombinant Proteins
1 Gene Ontology (GO) cellular component term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
About this table
RSBN1 for ontologies About GeneDecksing
Antibodies for RSBN1:
Assays for RSBN1: |
Protein
Domains/
Families
for RSBN1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5VWQ0 UniProtKB/Swiss-Prot: RSBN1_HUMAN, Q5VWQ0Similarity: Belongs to the round spermatid basic protein 1 family |
Gene Function
for RSBN1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IEA | -- |
About this table
RSBN1 for ontologies About GeneDecksing
|
Pathways & Interactions
for RSBN1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for RSBN1
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RSBN1
|
Drugs & Compounds
for RSBN1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for RSBN1
|
Transcripts
for RSBN1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for RSBN1 gene: NM_018364.3 Additional cDNA sequence: AK002082.1 AK022166.1 AK292552.1 AL050064.1 BC026155.1 CR627402.1 12 DOTS entries: DT.413026 DT.444261 DT.40124692 DT.121428295 DT.97841952 DT.121428239 DT.121428243 DT.91695050 DT.95281752 DT.121428268 DT.95259516 DT.95265395 24/135 AceView cDNA sequences (see all 135): AU133932 CF527941 AA382924 AI768601 CR627402 AW134518 BE301435 BE044188 D11984 BC026155 AW467256 BX478083 NM_018364 AA504548 AW337336 BQ002196 BE673207 AI365485 AA995184 CA432709 AI825693 BQ694562 BQ422861 AI696509
 highest scoring ESTs for RSBN1:AA778874 AA707635 AI023250 AI075979 AI261745 AI768513 AK002082 AU138233 AW134518 AW183679 Unigene Cluster for RSBN1: Round spermatid basic protein 1 Hs.486285 [show with all ESTs]Unigene Representative Sequence: NM_018364
GeneLoc Exon Structure
4 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369581 ENST00000476412 ENST00000261441(uc001edq.2 uc001edr.2)
ENST00000434941
|
Expression
for RSBN1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| RSBN1 expression in normal and diseased human tissues
1 / 2 / 3 13 probe-sets matching RSBN1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 74682_at2, 3
|
U95-E |
1 |
1.00 |
1.00 |
0.56 |
0.73 |
AA778874 |
1.00 |
1.00 |
1.00 |
1 |
| 52814_at2, 3
|
U95-B |
1 |
0.94 |
1.00 |
0.88 |
1.15 |
R45958 |
0.40 |
1.00 |
0.76 |
1 |
| 37828_at2, 3
|
U95-A |
1 |
0.75 |
1.00 |
0.61 |
1.13 |
AL050064 |
0.60 |
1.00 |
0.82 |
1 |
| 222789_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
R45958 |
0.40 |
1.00 |
0.76 |
1 |
| 222788_s_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
BE888593 |
0.80 |
1.00 |
0.91 |
1 |
| 222790_s_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AK022166 |
0.60 |
1.00 |
0.82 |
1 |
| 222791_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AK022166 |
0.60 |
1.00 |
0.82 |
1 |
| 213694_at2, 3
|
U133-A |
1 |
0.91 |
1.00 |
-- |
-- |
AW027347 |
0.40 |
1.00 |
0.76 |
1 |
| 222789_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 222788_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 222790_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 222791_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 213694_at2
|
U133Plus2 |
1 |
0.91 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
RSBN1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.486285
SABiosciences Custom PCR Arrays for RSBN1
|
Orthologs
for RSBN1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RSBN1 gene from 5/7 species (see all 7)
About this table Species with no ortholog for RSBN1
ENSEMBL Gene Tree for RSBN1 (if available) |
Paralogs
for RSBN1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for RSBN1 gene
- RSBN1L2
RSBN1 for paralogs About GeneDecksing
|
Genomic Variants
for RSBN1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 1 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for RSBN1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for RSBN1
4 CNVs: 97473 2322 3306 64644
1 Indel: 58324 | | QIAGEN SeqTarget long-range PCR primers for resequencing RSBN1 |
|
Disorders & Mutations
for RSBN1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RSBN1 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: RSBN1 (3 documents)
Export disorders and mutations for RSBN1 gene to outside databases
|
Medical News
for RSBN1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for RSBN1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10 PubMed articles for RSBN1 gene integrated from 7 sources:
(articles sorted by number of sources associating them with RSBN1)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes. (PubMed id 18305142)1, 7 Smyth D.J....Todd J.A. (2008)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Variants in TNFAIP3, STAT4, and C12orf30 loci associa ted with multiple autoimmune diseases are also associated with juvenile idiopat hic arthritis. (PubMed id 19565500)1 Prahalad S....Jorde L.B. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids. (PubMed id 14724137)1 Takahashi T....Nishimune Y. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (1996)
|
External Searches for RSBN1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RSBN1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RSBN1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RSBN1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RSBN1 gene:
Search GeneIP for patents involving RSBN1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RSBN1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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 |  |  |  | |
| |  | Search Tocris compounds for RSBN1 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for RSBN1 |
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