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Aliases & Descriptionsfor SAMD9L gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions sterile alpha motif domain containing 9-like1 2 OTTHUMP000002086752 KIAA20051 2 3 sterile alpha motif domain-containing protein 9-like2 FLJ398851 2 OTTHUMP000002086792 C7orf62 3 UEF12 DRIF22 3 OTTHUMP000002086762 SAM domain-containing protein 9-like2 3 OTTHUMP000002086802 chromosome 7 open reading frame 61 OTTHUMP000002086772 OTTHUMP000002086782 UEF3
Export aliases for SAMD9L gene to outside databases Previous GC identifers: GC07M092405 GC07M092597 GC07M092759
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Summariesfor SAMD9L gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor SAMD9L gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SAMD9L gene promoter: IRF-1 FOXO4 MEF-2A Other transcription factors Search SABiosciences Chromatin IP Primers for SAMD9L Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7q21.2 Ensembl cytogenetic band: 7q21.2 HGNC cytogenetic band: 7q21.2 SAMD9L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07M087368: view genomic region
(about GC identifiers )
Start:
87,368,164 bp from pter
End:
87,386,477 bp from pter
Size:
18,314 bases
Orientation:
minus strand
1 alternative location : Chr 7- 92,759,368-92,777,682
RefSeq DNA sequence: NC_000007.13 NT_007933.15 NT_079595.2
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Proteinsfor SAMD9L gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: SAM9L_HUMAN, Q8IVG5 (See
protein sequence )Recommended Name: Sterile alpha motif domain-containing protein 9-like Size : 1584 amino acids; 184533 Da
Sequence caution : Sequence=AAI27118.1; Type=Frameshift; Positions=1259; Sequence=AAI27119.1; Type=Frameshift;Positions=1516; Sequence=BAC04975.1; Type=Erroneous initiation; Sequence=BAC23102.1; Type=Erroneous initiation; Sequence=CAD38910.1; Type=Erroneous initiation;
Secondary accessions : A0JP23 A0JP24 A0PJG8 A4D1G8 Q2TV71 Q2TV75 Q2UZV8 Q8IWI4 Q8N3L9 Q8N875Alternative splicing : 2 isoforms : Q8IVG5-1 Q8IVG5-2 Explore the universe of human proteins at neXtProt for SAMD9L: NX_Q8IVG5 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins: NP_689916.2 ENSEMBL proteins: ENSP00000326247 ENSP00000405760 ENSP00000408796 ENSP00000391699 ENSP00000391387 ENSP00000396137 ENSP00000410062 ENSP00000377983 Human Recombinant Proteins Antibodies for SAMD9L: Assays for SAMD9L:
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Protein
Domains/ Familiesfor SAMD9L gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
SAMD9L for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8IVG5 ProtoNet protein and cluster: Q8IVG5
1 Blocks protein family : IPB001660 Sterile alpha motif SAM UniProtKB/Swiss-Prot: SAM9L_HUMAN, Q8IVG5 Similarity : Contains 1 SAM (sterile alpha motif) domain
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Gene Functionfor SAMD9L gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor SAMD9L gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for SAMD9L Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SAMD9L
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Drugs & Compoundsfor SAMD9L gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for SAMD9L
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Transcriptsfor SAMD9L gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for SAMD9L gene: NM_152703.2
Additional cDNA sequence: AB095926.1 AF474973.1 AK026672.1 AK097204.1 AK304307.1 AK304779.1 AL832264.1 AL834232.1 AY195582.1 AY195583.1 AY195584.1 AY195585.1 AY195586.1 AY195587.1 AY195588.1 BC029108.1 BC038974.1 BC127117.1 BC127118.1 DQ068177.1
4 DOTS entries : DT.303533 DT.95322412 DT.91701818 DT.121046737
24/92 AceView cDNA sequences (see all 92 ):
NM_152703 AI087313 BE675526 AK097204 AA648507 BG236517 BF058148 BC029108 BQ433442 AB095926 BU507807 AA490264 AW294127 BM470525 AI457736 AA253288 AI139687 AA490365 AL832264 AW337195 BU190148 AI674920 AA988857 AW675618
highest scoring ESTs for SAMD9L :AA215579 AB095926 AI038997 AI309599 CB267658 CB957001 W19045 AA215765 AA622528 AA648507 Unigene Cluster for SAMD9L:
Sterile alpha motif domain containing 9-like Hs.489118 [show with all ESTs ] Unigene Representative Sequence: NM_152703 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for SAMD9L ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 SP1 :                   SP2 :       -     -         SP3 :     -   -            
About this scheme ECgene alternative splicing isoforms for SAMD9L 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000318238 (uc003umh.1 uc003umj.1 uc003umi.1 uc010lfb.1 uc003umk.1 uc010lfc.1 uc010lfd.1 uc011khx.1 )ENST00000411955 ENST00000437805 ENST00000446959 ENST00000439952 ENST00000414791 ENST00000446033 ENST00000477816 ENST00000394472
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Expression for SAMD9L gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section SAMD9L expression in normal and diseased human tissues 1 / 2 / 3
10 probe-sets matching SAMD9L gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
80928_at2 , 3
U95-E
1
1.00
1.00
0.96
1.45
AI309599
0.80
1.00
0.91
1
90663_at2 , 3
U95-D
1
0.94
1.00
0.95
1.01
AA215579
0.80
1.00
0.91
1
74867_at2 , 3
U95-E
1
0.94
1.00
-0.13
0.38
AI038997
0.80
1.00
0.91
1
51024_at2 , 3
U95-B
1
0.31
1.00
0.98
1.19
AI400509
0.60
1.00
0.82
1
235643_at2 , 3
U133-B
1
1.00
1.00
--
--
BE886225
0.60
1.00
0.82
1
226603_at2 , 3
U133-B
1
1.00
1.00
--
--
BE966604
0.40
1.00
0.76
1
230036_at2 , 3
U133-B
1
0.36
1.00
--
--
BE669858
0.40
1.00
0.76
1
235643_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
226603_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
230036_at2
U133Plus2
1
0.36
1.00
--
--
--
--
--
--
--
About this table
SAMD9L for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --SOURCE GeneReport for Unigene cluster: Hs.489118 UniProtKB/Swiss-Prot: SAM9L_HUMAN, Q8IVG5 Tissue specificity : Widely expressed in adult and fetal tissues. Variable expression in tumors. Down-regulated inbreast cancer
SABiosciences Custom PCR Arrays for SAMD9L
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Orthologsfor SAMD9L gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for SAMD9L gene from 5/6 species (see all 6 )
About this table Species with no ortholog for SAMD9L ENSEMBL Gene Tree for SAMD9L (if available)
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Paralogsfor SAMD9L gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section Paralogs for SAMD9L gene SAMD9 2
SAMD9L for paralogs About GeneDecksing
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Genomic Variantsfor SAMD9L gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 7 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for SAMD9L (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SAMD9L: --
QIAGEN SeqTarget long-range PCR primers for resequencing SAMD9L
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Disorders & Mutationsfor SAMD9L gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
SAMD9L for disorders About GeneDecksing
OMIM: 611170 Export disorders and mutations for SAMD9L gene to outside databases
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Medical Newsfor SAMD9L gene (Possibly Related Articles in
Doctor's Guide )
About This Section --
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Publicationsfor SAMD9L gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 7 PubMed articles for SAMD9L gene integrated from 7 sources : (articles sorted by number of sources associating them with SAMD9L) Human sterile alpha motif domain 9, a novel gene identified as down- regulated in aggressive fibromatosis, is absent in the mouse. (PubMed id 17407603) 1 , 2 Li C.F.... Alman B.A. (2007) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Human chromosome 7: DNA sequence and biology. (PubMed id 12690205) 1 , 2 Scherer S.W.... Tsui L.-C. (2003) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 2 Olsen J.V....Mann M. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for SAMD9L gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SAMD9L gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SAMD9L gene
(According to HUGE )
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Specialized Databases showing SAMD9L gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for SAMD9L gene: Search GeneIP for patents involving SAMD9L GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SAMD9L gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for SAMD9L
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