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SEZ6L Gene

protein-coding   GIFtS: 55

GC22P009512
seizure related 6 homolog (mouse)-like
(Previous name: seizure related gene 6 (mouse)-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
seizure related 6 homolog (mouse)-like1 2     seizure related gene 6-like2
seizure related gene 6 (mouse)-like1     seizure 6-like protein2
OTTHUMP000001986482     KIAA09273
OTTHUMP000001986492     

External Ids:    HGNC: 107631   Entrez Gene: 235442   Ensembl: ENSG000001000957   UniProtKB: Q9BYH13   

Export aliases for SEZ6L gene to outside databases

Previous GC identifers: GC22P023261 GC22P023384 GC22P024890 GC22P024889 GC22P026565


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SE6L1_HUMAN, Q9BYH1
Function: May contribute to specialized endoplasmic reticulum functions in neurons (By similarity)

Gene Wiki entry for SEZ6L

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEZ6L gene promoter:
         RSRFC4   MEF-2A   GCNF-1   GCNF-2   Chx10   c-Myc   Max1   NF-kappaB1   FOXD3   AP-1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for SEZ6L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12.1   Ensembl cytogenetic band:  22q12.1   HGNC cytogenetic band: 22q12.1

SEZ6L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEZ6L gene location

GeneLoc gene densities for chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P009512:  view genomic region     (about GC identifiers)

Start:
9,512,935 bp from pter
End:
9,727,121 bp from pter
Size:
214,187 bases
Orientation:
plus strand

1 alternative location:
Chr22+ 26,565,440-26,779,562     
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: SE6L1_HUMAN, Q9BYH1 (See protein sequence)
Recommended Name: Seizure 6-like protein precursor  
Size: 1024 amino acids; 111782 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity)
Sequence caution: Sequence=BAA76771.2; Type=Erroneous initiation; Sequence=CAB37431.1; Type=Erroneous initiation;
Sequence=CAB43355.1; Type=Erroneous initiation;
PDB structures from and Proteopedia :
2YRA (3D)    
Secondary accessions: A0AUW7 B0QYG4 B0QYG5 O95917 Q5THY5 Q6IBZ4 Q6UXD4 Q9NUI3 Q9NUI4 Q9NUI5 Q9Y2E1
Q9Y3J6
Alternative splicing: 5 isoforms:  Q9BYH1-1   Q9BYH1-2   Q9BYH1-3   Q9BYH1-4   Q9BYH1-5   (Experimental confirmation may be lacking for some isoforms)

Explore the universe of human proteins at neXtProt for SEZ6L: NX_Q9BYH1 

REFSEQ proteins (6 alternative transcripts): 
NP_001171702.1  NP_001171703.1  NP_001171704.1  NP_001171705.1  NP_001171706.1  NP_066938.2  


ENSEMBL proteins: 
ENSP00000384838 ENSP00000381245 ENSP00000248933 ENSP00000384772 ENSP00000404225 ENSP00000342661 
ENSP00000384733 ENSP00000354185 ENSP00000397274 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
GenScript Custom Purified and Recombinant Proteins Services for SEZ6L 
Novus Biologicals Protein for SEZ6L
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005783 endoplasmic reticulum IEA--
GO:0005789 endoplasmic reticulum membrane IEA--
GO:0016020 membrane IEA--
GO:0016021 integral to membrane IEA--
About this table

SEZ6L for ontologies           About GeneDecksing



Antibodies for SEZ6L: 
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
R&D Systems Antibodies for SEZ6L (BSRP-B)
Browse OriGene Antibodies
GenScript Custom Superior Antibodies Services for SEZ6L 
Browse antibodies at Epitomics

Assays for SEZ6L: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for SEZ6L 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for SEZ6L 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SEZ6L for domains           About GeneDecksing

3 InterPro domains/families:
 IPR000436 Sushi_SCR_CCP
 IPR000859 CUB
 IPR016060 Complement_control_module

Graphical View of Domain Structure for InterPro Entry Q9BYH1

ProtoNet protein and cluster: Q9BYH1

2 Blocks protein families:
IPB000436 Sushi domain/SCR domain/CCP module
IPB000859 CUB domain


UniProtKB/Swiss-Prot: SE6L1_HUMAN, Q9BYH1
Similarity: Belongs to the SEZ6 family
Similarity: Contains 3 CUB domains
Similarity: Contains 5 Sushi (CCP/SCR) domains


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: SE6L1_HUMAN, Q9BYH1
Function: May contribute to specialized endoplasmic reticulum functions in neurons (By similarity)

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SEZ6L
Sigma-Aldrich shRNA for SEZ6L
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 6): SEZ6L
OriGene shRNA RFP (see all 6): SEZ6L
OriGene basic RS shRNA (see all 6): SEZ6L
OriGene siRNA (see all 6): SEZ6L
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SEZ6L 
miRNA:Sigma-Aldrich microRNA Mimics for SEZ6L
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SEZ6L 
Search SABiosciences for Assays for microRNAs that regulate SEZ6L

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector (see all 6): SEZ6L
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 6): SEZ6L
OriGene untagged cDNA clones in CMV expression vector (see all 2): SEZ6L
OriGene 3'-UTR clone: SEZ6L 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for SEZ6L 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for SEZ6L 

Genatlas biochemistry entry for SEZ6L:
seizure related gene 6 (mouse)-like
Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sez6l):
behavior/neurologicalnervous system

SEZ6L for phenotypes           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for SEZ6L 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEZ6L

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SEZ6L


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SEZ6L
Sigma-Aldrich shRNA for SEZ6L
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 6): SEZ6L
OriGene shRNA RFP (see all 6): SEZ6L
OriGene basic RS shRNA (see all 6): SEZ6L
OriGene siRNA (see all 6): SEZ6L
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SEZ6L 
miRNA: Sigma-Aldrich microRNA Mimics for SEZ6L
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SEZ6L 
Search SABiosciences for Assays for microRNAs that regulate SEZ6L
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector (see all 6): SEZ6L
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 6): SEZ6L
OriGene untagged cDNA clones in CMV expression vector (see all 2): SEZ6L
OriGene 3'-UTR Clone: SEZ6L 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for SEZ6L 
Primers: OriGene genome-wide validated SYBR primer pairs: SEZ6L
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for SEZ6L: PPH14135A

REFSEQ mRNAs for SEZ6L gene (6 alternative transcripts): 

NM_001184773.1  NM_001184774.1  NM_001184775.1  NM_001184776.1  NM_001184777.1  NM_021115.4  

Additional cDNA sequence: 

AB023144.2 AB041736.1 AK294790.1 AL050253.1 AY358405.1 BC037846.2 BC126115.1 BC143851.1 
BC143854.1 CR456574.1 

7 DOTS entries:

DT.111922  DT.97838043  DT.102829718  DT.75132234  DT.91644521  DT.40271865  DT.97769534 

24/100 AceView cDNA sequences (see all 100):

BF062276 AI360299 BM875435 BF591700 BE220403 AI015798 F05756 CR456574 
AI360241 AY358405 BE503273 BE222339 AI363908 H55462 BI962863 Z38680 
BI962921 AB041736 NM_021115 AI281980 N46729 AI365630 BF447755 BE219812 

highest scoring ESTs for SEZ6L:

AB023144 AA133829 AA629566 AA663853 AA991780 AB041736 AI015798 AI281980 AI360241 AI360299 

Unigene Cluster for SEZ6L:

Seizure related 6 homolog (mouse)-like
Hs.194766  [show with all ESTs]
Unigene Representative Sequence: NM_021115


GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SEZ6L (see all 10)

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b · 17c ^
SP1:                          -                                                                                   -     -                                       
SP2:                          -                                                                                   -     -                                       
SP3:                                                                                                              -     -                                       
SP4:                          -                                                                       -     -     -     -           -                           
SP5:                          -                                                                                   -     -     -     -                           

ExUns: 18a · 18b · 18c · 18d
SP1:                        
SP2:                        
SP3:                        
SP4:                        
SP5:                        

About this scheme

ECgene alternative splicing isoforms for SEZ6L
11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000403121 ENST00000483291 ENST00000398184 ENST00000248933 ENST00000404234(uc003acb.2 uc003acc.2 uc011akc.1 uc011akd.1 uc003ace.2 uc011ake.1)
ENST00000422412 ENST00000343706 ENST00000494013 ENST00000402979(uc003acf.1 uc010gvc.1)
ENST00000360929(uc003acd.2) ENST00000411842

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

SEZ6L expression in normal and diseased human tissues

1  / 2  / 3

10 probe-sets matching SEZ6L gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
32968_s_at2, 3 U95-A 1 1.00 1.00 0.64 1.70 AL050253 0.80 1.00 0.91 1
33735_at2, 3 U95-A 1 0.62 1.00 0.98 0.63 AB023144 1.00 1.00 1.00 1
211894_x_at2, 3 U133-A 1 1.00 1.00 -- -- AB041736 0.80 1.00 0.91 1
207873_x_at2, 3 U133-A 1 0.91 1.00 -- -- NM_021115 0.60 1.00 0.82 1
216047_x_at2, 3 U133-A 1 0.82 1.00 -- -- AL050253 0.80 1.00 0.91 1
213609_s_at2, 3 U133-A 1 0.46 1.00 -- -- AB023144 1.00 1.00 1.00 1
211894_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
207873_x_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
216047_x_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
213609_s_at2 U133Plus2 1 0.46 1.00 -- -- -- -- -- -- --
About this table

SEZ6L for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
SEZ6L gene expression
SEZ6L gene electronic northern expression
SEZ6L gene sage expression
About these images

CGAP SAGE TAG: ACGAGTCATT

SOURCE GeneReport for Unigene cluster: Hs.194766

Expression variation in blood from EXPOLDB for SEZ6L

UniProtKB/Swiss-Prot: SE6L1_HUMAN, Q9BYH1
Tissue specificity: Widely expressed, including adult and fetal brains and lungs. Not expressed in all lung cancer cell
lines

Primers: OriGene genome-wide validated SYBR primer pairs: SEZ6L
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for SEZ6L: PPH14135A
    SABiosciences Custom PCR Arrays for SEZ6L 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SEZ6L gene from 5/6 species (see all 6)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
SEZ6L1   -- seizure related 6 homolog (mouse)-like 88.36(n)
92.54(a)
486329  XM_543455.2  XP_543455.2 
chimpanzee
(Pan troglodytes)
SEZ6L1   -- seizure related 6 homolog (mouse)-like 94.9(n)
93.67(a)
458722  XM_515042.2  XP_515042.2 
cow
(Bos taurus)
SEZ6L1   -- seizure related 6 homolog (mouse)-like 86.57(n)
87.59(a)
520525  XM_598772.3  XP_598772.3 
rat
(Rattus norvegicus)
RGD15636281   -- similar to Seizure 6-like protein precursor 82.07(n)
86.37(a)
304554  XM_222244.4  XP_222244.4 
mouse
(Mus musculus)
Sez6l1 , 5 5 (54.72 cM)5
seizure related 6 homolog like1, 5 82.07(n)1
85.74(a)1
567471  NM_019982.21  NP_064366.21 
 AB2067905  AF2203555  (see all 19)
About this table        Species with no ortholog for SEZ6L

ENSEMBL Gene Tree for SEZ6L (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for SEZ6L gene
SEZ6L22  SELP2  SEZ62  SELE2  SELL2  SVEP12  

SEZ6L for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/2598 NCBI SNPs in SEZ6L are shown (see all 2598)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 22 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs255931,2
--26694156(+) AAAAG-/CAACAACA 5 -- int10--------
rs793591,2
C,A26598096(+) aggatG/Agtctt 5 -- int13Minor allele frequency- A:0.33NA WA 6
rs793601,2
C,F,A,H,26599293(+) TTTTGC/TTCTCT 5 -- int115Minor allele frequency- T:0.39EA NS NA WA 832
rs1347551,2
C,F,26565156(+) CCTGGC/TCTGGC 5 -- ng513Minor allele frequency- T:0.25NA WA 124
rs1347561,2
C,F,26566685(+) CACCTA/GGGAGA 5 -- int11Minor allele frequency- G:0.26WA 50
rs1347571,2
C,F,A,26566757(+) AATGCG/TCTCCT 5 -- int15Minor allele frequency- T:0.24NS NA WA 364
rs1347581,2
C,F,A,26573043(+) TAAATT/GACTTT 5 -- int112Minor allele frequency- G:0.42NS EA NA WA 916
rs1347591,2
C,F,A,26573240(+) atgtgA/GaATCA 5 -- int18Minor allele frequency- G:0.43NS EA NA WA 496
rs1347601,2
C,F,O,26573345(+) TGCAAA/GCACAA 5 -- int18Minor allele frequency- G:0.17MN NS EA NA WA 728
rs1347611,2
C,F,A,H,26581298(+) acccaA/Gtgaga 5 -- int110Minor allele frequency- G:0.43EA NS NA WA 676
About this table

HapMap Linkage Disequilibrium images for SEZ6L (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SEZ6L
     1 CNV: 2273

QIAGEN SeqTarget long-range PCR primers for resequencing SEZ6L 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SEZ6L for disorders           About GeneDecksing

OMIM: 607021

Human Genome Epidemiology (HuGE) Navigator: SEZ6L (7 documents)

Export disorders and mutations for SEZ6L gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/17 PubMed articles for SEZ6L gene, integrated from 7 sources (see all 17):
(articles sorted by number of sources associating them with SEZ6L)
  1. Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line. (PubMed id 11175339)1, 2, 7 Nishioka M....Yokota J. (2000)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
  4. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (2003)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
  6. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. (PubMed id 11992124)1, 2 Suzuki H.... Baylin S.B. (2002)
  7. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
  8. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
  9. Seizure 6-like (SEZ6L) gene and risk for lung cancer. (PubMed id 17804757)1, 7 Gorlov I.P....Amos C.I. (2007)
  10. Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease i n the atherosclerosis risk in communities study. (PubMed id 19955471)1 Bressler J....Boerwinkle E. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23544 HGNC: 10763 AceView: SEZ6L Ensembl:ENSG00000100095 euGenes: HUgn23544
ECgene: SEZ6L H-InvDB: SEZ6L

(According to HUGE)
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HUGE: KIAA0927

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
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Patent Information for SEZ6L gene:
Search GeneIP for patents involving SEZ6L

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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 ELISAs and CLIAs for SEZ6L
       

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