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SLC16A7 Gene

protein-coding   GIFtS: 53

GC12P057131
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
(Previous names: solute carrier family 16 (monocarboxylic acid transporters), member 7 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for SLC16A7 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)1 2
MCT21 2 3 5
solute carrier family 16 (monocarboxylic acid transporters), member 71 2
Solute carrier family 16 member 72 3
MCT 22 3
monocarboxylate transporter 22

External Ids:    HGNC: 109281   Entrez Gene: 91942   Ensembl: ENSG000001185967   UniProtKB: O606693   

Export aliases for SLC16A7 gene to outside databases

Previous GC identifers: GC12P059779 GC12P060132 GC12P058276 GC12P058369


Summaries
for SLC16A7 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MOT2_HUMAN, O60669
Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many
monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and
the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter


Genomic Views
for SLC16A7 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC16A7 gene promoter:
         Bach1   Nkx3-1 v4   Nkx3-1 v3   Nkx3-1 v2   Nkx3-1 v1   Nkx3-1   Sox9   POU2F1   CUTL1   Pbx1a   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for SLC16A7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q14.1   HGNC cytogenetic band: 12q13

SLC16A7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC16A7 gene location

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P057131:  view genomic region     (about GC identifiers)

Start:
 57,131,582 bp from pter
End:
 57,223,874 bp from pter
Size:
 92,293 bases
Orientation:
 plus strand

1 alternative location:
Chr12+ 60,083,126-60,175,407     
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  

Proteins
for SLC16A7 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: MOT2_HUMAN, O60669 (See protein sequence)
Recommended Name: Monocarboxylate transporter 2  
Size: 478 amino acids; 52200 Da
Subunit: Interacts with GRID2IP (By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q9UPB3

Explore the universe of human proteins at neXtProt for SLC16A7: NX_O60669 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_004722.2  

    ENSEMBL proteins: 
    ENSP00000261187 


    Human Recombinant Proteins 
    Millipore Purified and/or Recombinant SLC16A7 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: SLC16A7
    GenScript Custom Purified and Recombinant Proteins Services for SLC16A7 
    Novus Biologicals Protein for SLC16A7
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624 membrane fraction IEA--
    GO:0005886 plasma membrane TAS--
    GO:0005887 integral to plasma membrane TAS9786900
    GO:0016021 integral to membrane ----
    About this table

    SLC16A7 for ontologies           About GeneDecksing



    Antibodies for SLC16A7: 
    Millipore Mono- and Polyclonal Antibodies for the study of SLC16A7
    Sigma-Aldrich Antibodies for SLC16A7
    Browse R&D Systems for Antibodies
    OriGene Antibodies: SLC16A7
    GenScript Custom Superior Antibodies Services for SLC16A7 
    Novus Biologicals Antibody for SLC16A7
    Browse antibodies at Epitomics

    Assays for SLC16A7: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC16A7 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for SLC16A7 

    Protein Domains/
    Families
    for SLC16A7 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC16A7 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011701 MFS_1
     IPR020846 Major_facilitator_SF
     IPR004743 Monocarb_transpt
     IPR016196 MFS_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry O60669

    ProtoNet protein and cluster: O60669

    UniProtKB/Swiss-Prot: MOT2_HUMAN, O60669
    Similarity: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family


    Gene Function
    for SLC16A7 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: MOT2_HUMAN, O60669
    Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many
    monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and
    the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SLC16A7
    Sigma-Aldrich shRNA for SLC16A7
    OriGene 29mer shRNA kits in GFP-retroviral vector: SLC16A7
    OriGene shRNA RFP: SLC16A7
    OriGene basic RS shRNA: SLC16A7
    OriGene siRNA: SLC16A7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC16A7 
    miRNA:Sigma-Aldrich microRNA Mimics for SLC16A7
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC16A7 
    6 SABiosciences Assays for microRNAs that regulate SLC16A7:
    hsa-miR-141 hsa-miR-489 hsa-miR-1271 hsa-miR-200a hsa-miR-96 hsa-miR-7

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: SLC16A7
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: SLC16A7
    OriGene untagged cDNA clones in CMV expression vector: SLC16A7
    OriGene 3'-UTR clone: SLC16A7 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: SLC16A7 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for SLC16A7 

    Genatlas biochemistry entry for SLC16A7:
    solute carrier family 16,member A7,monocarboxylic acids transporter,high affinity pyruvate transporter,restricted in
    normal tissues,widely expressed in cancer cell lines

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005477 pyruvate secondary active transmembrane transporter activity TAS9786900
    GO:0008028 monocarboxylic acid transmembrane transporter activity TAS--
    GO:0015293 symporter activity IEA--
    GO:0015355 secondary active monocarboxylate transmembrane transporter activity IEA--
    About this table

    SLC16A7 for ontologies           About GeneDecksing


    Pathways & Interactions
    for SLC16A7 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    SLC16A7 for pathways           About GeneDecksing

    2 Millipore Pathways for SLC16A7
        Selected targets of ESR1
    Selected targets of HNF1

        SABiosciences Custom Pathway-Focused PCR Arrays for SLC16A7 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC16A7

    5/17 Interacting proteins for SLC16A7 (ENSP000002611873) via UniProtKB, MINT, and/or STRING (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BSGENSP000003337693STRING: ENSP00000333769
    HRASENSP000003733823STRING: ENSP00000373382
    SLC16A1ENSP000003586403STRING: ENSP00000358640
    SLC16A8ENSP000003217353STRING: ENSP00000321735
    SLC1A7ENSP000003605493STRING: ENSP00000360549
    About this table

    3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006848 pyruvate transport TAS9786900
    GO:0015711 organic anion transport ----
    GO:0055085 transmembrane transport TAS--
    About this table

    SLC16A7 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC16A7 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    SLC16A7 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC16A7
    5 Novoseek chemical compound relationships for SLC16A7 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lactate 70.5 18 19404741 (3), 15505343 (2), 17502341 (2), 10921872 (1) (see all 10)
    pyruvate 64.2 7 9786900 (2), 16604139 (1), 7829520 (1)
    rapamycin 26.1 4 17394554 (1), 18093179 (1)
    glucose 24.3 3 11272148 (1), 19393029 (1)
    glutamate 10.7 1 11926280 (1)
    About this table



    Transcripts
    for SLC16A7 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SLC16A7
    Sigma-Aldrich shRNA for SLC16A7
    OriGene 29mer shRNA kits in GFP-retroviral vector: SLC16A7
    OriGene shRNA RFP: SLC16A7
    OriGene basic RS shRNA: SLC16A7
    OriGene siRNA: SLC16A7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC16A7 
    miRNA: Sigma-Aldrich microRNA Mimics for SLC16A7
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC16A7 
    6 SABiosciences Assays for microRNAs that regulate SLC16A7:
    hsa-miR-141 hsa-miR-489 hsa-miR-1271 hsa-miR-200a hsa-miR-96 hsa-miR-7
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: SLC16A7
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: SLC16A7
    OriGene untagged cDNA clones in CMV expression vector: SLC16A7
    OriGene 3'-UTR Clone: SLC16A7 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: SLC16A7 
    Primers: OriGene genome-wide validated SYBR primer pairs: SLC16A7
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for SLC16A7: PPH20892A

    REFSEQ mRNAs for SLC16A7 gene: 

    NM_004731.3  

    Additional cDNA sequence: 

    AF049608.1 AF058056.1 AK301725.1 AK310281.1 AK313345.1 BC007463.1 BC030693.2 

    5 DOTS entries:

    DT.203003  DT.91749689  DT.91749690  DT.100684814  DT.121107285 

    24/28 AceView cDNA sequences (see all 28):

    BC030693 N42889 AI796731 AI473884 CD678732 CB241451 NM_004731 CF887757 
    CF891525 AI302205 AF058056 AL597759 F01173 AI823653 AI308108 BG401357 
    AL600173 BC007463 BX112287 AI760494 AF049608 BG721447 AA731520 N34486 

    highest scoring ESTs for SLC16A7:

    AA731520 AF058056 AF049608 AI302205 AI308108 AI473884 AI760494 AI796731 AW975728 BC007463 

    Unigene Cluster for SLC16A7:

    Solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
    Hs.439643  [show with all ESTs]
    Unigene Representative Sequence: NM_004731


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000261187(uc001sqs.2 uc001sqt.2 uc001squ.2 uc009zqi.2 uc010ssi.1)


    Expression
    for SLC16A7 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    SLC16A7 expression in normal and diseased human tissues

    1  / 2  / 3

    5 probe-sets matching SLC16A7 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    35547_at2, 3 U95-A 1 0.94 1.00 1.00 1.00 AF058056 1.00 1.00 1.00 1
    210807_s_at2, 3 U133-A 1 0.82 1.00 -- -- AF049608 0.80 1.00 0.91 1
    207057_at2, 3 U133-A 1 0.64 1.00 -- -- NM_004731 0.60 1.00 0.82 1
    210807_s_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    207057_at2 U133Plus2 1 0.64 1.00 -- -- -- -- -- -- --
    About this table

    SLC16A7 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    SLC16A7 gene expression
    SLC16A7 gene electronic northern expression
    SLC16A7 gene sage expression
    About these images

    CGAP SAGE TAG: TACACAGAGT

    SOURCE GeneReport for Unigene cluster: Hs.439643

    Expression variation in blood from EXPOLDB for SLC16A7

    UniProtKB/Swiss-Prot: MOT2_HUMAN, O60669
    Tissue specificity: High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle,
    brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells

    Primers: OriGene genome-wide validated SYBR primer pairs: SLC16A7
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for SLC16A7: PPH20892A
        SABiosciences Custom PCR Arrays for SLC16A7 


    Orthologs
    for SLC16A7 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for SLC16A7 gene from 5/8 species (see all 8)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 SLC16A71   -- solute carrier family 16, member 7 (monocarboxylic more 83.82(n)
    82.56(a)    		 481138  XM_538259.1  XP_538259.1 
    chimpanzee
    (Pan troglodytes)    		 SLC16A71   -- solute carrier family 16, member 7 (monocarboxylic more 99.86(n)
    100(a)    		 467047  XM_001166633.1  XP_001166633.1 
    cow
    (Bos taurus)    		 SLC16A71   -- solute carrier family 16, member 7 (monocarboxylic more 81.86(n)
    80.88(a)    		 614573  NM_001076336.1  NP_001069804.1 
    rat
    (Rattus norvegicus)    		 Slc16a71   -- solute carrier family 16, member 7 (monocarboxylic more 76.52(n)
    73.88(a)    		 29735  NM_017302.1  NP_058998.1 
    mouse
    (Mus musculus)    		 Slc16a71 , 5 10 (72.31 cM)5
    		 solute carrier family 16 (monocarboxylic acid transporters), more1, 5 76.56(n)1
    74.11(a)1    		 205031  NM_011391.11  NP_035521.11 
     AF0580545  AK0766125  (see all 12)
    About this table        Species with no ortholog for SLC16A7

    ENSEMBL Gene Tree for SLC16A7 (if available)

    Paralogs
    for SLC16A7 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for SLC16A7 gene
    LOC4404592  SLC16A12  SLC16A32  SLC16A122  SLC16A52  SLC16A82  SLC16A62  

    SLC16A7 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC16A7 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for SLC16A7
         2 CNVs: 86416 66240
    QIAGEN SeqTarget long-range PCR primers for resequencing SLC16A7 

    Disorders & Mutations
    for SLC16A7 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC16A7 for disorders           About GeneDecksing

    OMIM: 603654

    Human Genome Epidemiology (HuGE) Navigator: SLC16A7 (2 documents)

    Export disorders and mutations for SLC16A7 gene to outside databases

    Medical News
    for SLC16A7 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for SLC16A7 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/41 PubMed articles for SLC16A7 gene, integrated from 7 sources (see all 41):
    (articles sorted by number of sources associating them with SLC16A7)
    1. Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. (PubMed id 9786900)1, 2, 3, 7 Lin R.-Y.... Golde D.W. (1998)
    2. Distribution of the monocarboxylate transporter MCT2 in human cerebral cortex: an immunohistochemical study. (PubMed id 18598673)1, 7 Chiry O....Pellerin L. (2008)
    3. The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells. (PubMed id 17502341)1, 7 Wang Q. and Morris M.E. (2007)
    4. Hypoxia stimulates lactate release and modulates mono carboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes. (PubMed id 19876643)1, 7 PAcrez de Heredia F....Trayhurn P. (2010)
    5. Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas. (PubMed id 18188595)1, 7 Pinheiro C....Baltazar F. (2008)
    6. Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44. (PubMed id 20454640)1, 7 Pinheiro C....Baltazar F. (2010)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Monocarboxylate transport in human corneal epithelium and cell lines. (PubMed id 20035863)1 Vellonen K.S....Urtti A. (2010 Feb 19)
    9. Sequential use of transcriptional profiling, expressi on quantitative trait mapping, and gene association implicates MMP20 in human k idney aging. (PubMed id 19834535)1 Wheeler H.E....Kim S.K. (2009)
    10. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)

    External Searches for SLC16A7 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC16A7 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9194 HGNC: 10928 AceView: SLC16A7 Ensembl:ENSG00000118596 euGenes: HUgn9194
    ECgene: SLC16A7 H-InvDB: SLC16A7

    Other Databases showing SLC16A7 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC16A7 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for SLC16A7 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for SLC16A7 gene:
    Search GeneIP for patents involving SLC16A7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for SLC16A7 gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for SLC16A7 Antibodies for SLC16A7
     Super-pooled esiRNAs for SLC16A7 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for SLC16A7 microRNA Mimics for SLC16A7
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC16A7
     SeqTarget long-range PCR primers for resequencing SLC16A7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC16A7
     GenScript Custom Purified and Recombinant Proteins Services for SLC16A7 GenScript cDNA clones with any tag delivered in your preferred vector for SLC16A7
     GenScript Custom Assay Services for SLC16A7 GenScript Custom Superior Antibodies Services for SLC16A7
     GenScript Custom overexpressing Cell Line Services for SLC16A7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SLC16A7 promoter
     Search Chromatin IP Primers for SLC16A7
     RT2 qPCR Primer Assay for SLC16A7
     Search GNC Networks for SLC16A7
     Assays for microRNAs that regulate SLC16A7
     SABiosciences Custom PCR Arrays for SLC16A7
     Search Tocris compounds for SLC16A7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for SLC16A7
     Proteins for SLC16A7
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for SLC16A7
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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