Home
GeneCards Guide
Suite
- GeneALaCart
- GeneDecks
- GeneIP
- GeneNote
- GeneAnnot
- GeneLoc
- GeneTide
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

SLC17A3 Gene

protein-coding GIFtS: 51

GC06M025788

solute carrier family 17 (sodium phosphate), member 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
solute carrier family 17 (sodium phosphate), member 3¹ ²		Na(+)/PI cotransporter 4² ³
NPT4¹ ² ³ ⁵		OTTHUMP00000016126²
Solute carrier family 17 member 3² ³		sodium-dependent phosphate transport protein 4²
Sodium/phosphate cotransporter 4² ³

External Ids:	HGNC: 10931¹	Entrez Gene: 10786²	Ensembl: ENSG00000124564⁷	UniProtKB: O00476³

Export aliases for SLC17A3 gene to outside databases

Previous GC identifers: GC06M025902 GC06M025953 GC06M025833

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476

Function: May be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SLC17A3 gene promoter:
         XBP-1   ZID   E47   MyoD   Pax-5   NRSF form 2   NRSF form 1   HNF-1A   Nkx3-1 v4   Nkx3-1 v3
         Other transcription factors

Search SABiosciences Chromatin IP Primers for SLC17A3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p22.2 HGNC cytogenetic band: 6p21.3

SLC17A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC17A3 gene location

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M025788: view genomic region (about GC identifiers)

Start:	25,788,565 bp from pter
End:	25,817,700 bp from pter
Size:	29,136 bases
Orientation:	minus strand

1 alternative location:

Chr6- 25,833,294-25,882,514

RefSeq DNA sequence:

NC_000006.11 NT_007592.15

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476 (See protein sequence)

Recommended Name: Sodium-dependent phosphate transport protein 4

Size: 420 amino acids; 46106 Da

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Sequence caution: Sequence=AAB53423.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: B7WNJ5 Q8WWC7 Q9H533

Explore the universe of human proteins at neXtProt for SLC17A3: NX_O00476

REFSEQ proteins (2 alternative transcripts):

NP_001091956.1 NP_006623.2

ENSEMBL proteins:

ENSP00000421855 ENSP00000424027 ENSP00000380250 ENSP00000353873 ENSP00000355307 ENSP00000424729

ENSP00000415622

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates
	GenScript Custom Purified and Recombinant Proteins Services for SLC17A3
	Novus Biologicals Protein for SLC17A3
	Novus Biologicals Lysate for SLC17A3
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

5/9 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 9):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005624	membrane fraction	--	--
GO:0005737	cytoplasm	IDA	--
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IDA	15505377
GO:0005887	integral to plasma membrane	IDA	--

About this table

SLC17A3 for ontologies About GeneDecksing

Antibodies for SLC17A3:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for SLC17A3
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies
	GenScript Custom Superior Antibodies Services for SLC17A3
	Novus Biologicals Antibodies for SLC17A3
	Browse antibodies at Epitomics

Assays for SLC17A3:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SLC17A3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SLC17A3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC17A3 for domains About GeneDecksing

4 InterPro domains/families:

IPR011701 MFS_1

IPR017373 Na-dep_P-transpt_4_prd

IPR020846 Major_facilitator_SF

IPR016196 MFS_general_subst_transpt

Graphical View of Domain Structure for InterPro Entry O00476

ProtoNet protein and cluster: O00476

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476

Similarity: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476

Function: May be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity)

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SLC17A3 Sigma-Aldrich shRNA for SLC17A3
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): SLC17A3 OriGene shRNA RFP (see all 2): SLC17A3 OriGene basic RS shRNA (see all 2): SLC17A3 OriGene siRNA (see all 2): SLC17A3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC17A3

miRNA:		Sigma-Aldrich microRNA Mimics for SLC17A3 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC17A3
		Search SABiosciences for Assays for microRNAs that regulate SLC17A3

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): SLC17A3 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): SLC17A3 OriGene untagged cDNA clones in CMV expression vector (see all 3): SLC17A3 Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for SLC17A3
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for SLC17A3

Genatlas biochemistry entry for SLC17A3:

solute carrier family 17 (sodium/phosphate cotransport) member 3,expressed in liver and kidney

5/8 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 8):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005436	sodium:phosphate symporter activity	ISS	--
GO:0008308	voltage-gated anion channel activity	IDA	--
GO:0008514	organic anion transmembrane transporter activity	IDA	--
GO:0015143	urate transmembrane transporter activity	IDA	--
GO:0015238	drug transmembrane transporter activity	IDA	--

About this table

SLC17A3 for ontologies About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Pathway-Focused PCR Array including SLC17A3: PAHS-093A

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SLC17A3

5/10 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 10):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006796	phosphate metabolic process	--	--
GO:0006811	ion transport	IEA	--
GO:0006814	sodium ion transport	ISS	--
GO:0006817	phosphate transport	ISS	--
GO:0015711	organic anion transport	IDA	--

About this table

SLC17A3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SLC17A3

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for SLC17A3 Sigma-Aldrich shRNA for SLC17A3
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): SLC17A3 OriGene shRNA RFP (see all 2): SLC17A3 OriGene basic RS shRNA (see all 2): SLC17A3 OriGene siRNA (see all 2): SLC17A3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC17A3

miRNA:		Sigma-Aldrich microRNA Mimics for SLC17A3 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC17A3
		Search SABiosciences for Assays for microRNAs that regulate SLC17A3

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): SLC17A3 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): SLC17A3 OriGene untagged cDNA clones in CMV expression vector (see all 3): SLC17A3 Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for SLC17A3

Primers:		OriGene genome-wide validated SYBR primer pairs: SLC17A3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for SLC17A3: PPH17019A

REFSEQ mRNAs for SLC17A3 gene (2 alternative transcripts):

NM_001098486.1 NM_006632.3

Additional cDNA sequence:

AK296070.1 AK296082.1 AK298271.1 AK298297.1 AK298367.1 BC017952.1 U90545.1 Z83953.1

5 DOTS entries:

DT.403125 DT.100742561 DT.121332300 DT.40120631 DT.95204537

19 AceView cDNA sequences:

AI222455 AI733707 CB163247 BC017952 BG427288 BX107915 U90545 NM_006632

AI244777 AA858296 AI821963 BF431676 Z83953 AI792430 AI311320 AA706766

AI247271 AA814153 BG399960

highest scoring ESTs for SLC17A3:

U90545 AA706766 AA814153 AI222455 AI244777 AI247271 AI733707 AI792430 BC017952 BG399960

Unigene Cluster for SLC17A3:

Solute carrier family 17 (sodium phosphate), member 3

Hs.327179 [show with all ESTs]

Unigene Representative Sequence: AK298271

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SLC17A3 (see all 6)

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	^	10	^	11a	·	11b	^	12	^	13	^	14
SP1:							-						-												-
SP2:			-		-		-						-												-
SP3:							-						-		-
SP4:							-
SP5:													-		-

About this scheme

ECgene alternative splicing isoforms for SLC17A3
10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000481949 ENST00000505420 ENST00000397060(uc003nfk.3 uc003nfi.3)

ENST00000360657 ENST00000361703 ENST00000509714(uc011djz.1) ENST00000506105

ENST00000503922(uc011dka.1) ENST00000308453 ENST00000449356

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

SLC17A3 expression in normal and diseased human tissues

¹ / ² / ³

3 probe-sets matching SLC17A3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34436_at²^{, 3}	U95-A	1	0.56	1.00	1.00	1.00	U90545	1.00	0.80	0.91	1
207298_at²^{, 3}	U133-A	1	0.64	1.00	--	--	NM_006632	0.60	0.83	0.73	1
207298_at²	U133Plus2	1	0.64	1.00	--	--	--	--	--	--	--

About this table

SLC17A3 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

SLC17A3 gene electronic northern expression

About these images

CGAP SAGE TAG: GTGGGAGGCT

SOURCE GeneReport for Unigene cluster: Hs.327179

Expression variation in blood from EXPOLDB for SLC17A3

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476

Tissue specificity: Expressed mainly in the liver and kidney, very low levels in the small intestine and testis

Primers:		OriGene genome-wide validated SYBR primer pairs: SLC17A3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for SLC17A3: PPH17019A

SABiosciences Expression via Pathway-Focused PCR Array including SLC17A3: PAHS-093A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SLC17A3 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SLC17A3¹	--	solute carrier family 17 (sodium phosphate), member more	81.32(n) 71.37(a)	478741 XM_535908.2 XP_535908.2
chimpanzee (Pan troglodytes)	SLC17A3¹	--	solute carrier family 17 (sodium phosphate), member more	99.33(n) 98.8(a)	462488 XM_518284.2 XP_518284.2
cow (Bos taurus)	SLC17A3¹	--	solute carrier family 17 (sodium phosphate), member more	80.28(n) 70.93(a)	519345 NM_001075787.1 NP_001069255.1
rat (Rattus norvegicus)	Slc17a3¹	--	solute carrier family 17 (sodium phosphate), member more	74.16(n) 64.86(a)	266730 NM_153622.1 NP_705886.1
mouse (Mus musculus)	Slc17a3^{1 , 5}	13 (9.95 cM)⁵	solute carrier family 17 (sodium phosphate), member more^{1, 5}	73.56(n)¹ 64.66(a)¹	105355¹ NM_134069.2¹ NP_598830.1¹ AA986956⁵ AI427938⁵ (see all 14)

About this table Species with no ortholog for SLC17A3

ENSEMBL Gene Tree for SLC17A3 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SLC17A3 gene

SLC17A4² SLC17A1² SLC17A5² SLC17A2²

SLC17A3 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs501220^1,2	C,F,A,	25873025(-)	`GACCTG/TTCTGT`	2	--	int¹		10	MN NS EA NA WA	727
rs523383^1,2	C,F,A,	25869848(-)	`tgctcT/Cttctt`	2	--	int¹ trp³		11	NS EA NA	918
rs548987^1,2	C,F,O,	25869371(-)	`GGTCAG/CAACCT`	2	--	int¹		105	EA NA NS MN PA EU CA WA	5948
rs555460^1,2	C,F,	25870655(+)	`TGCTCC/TTTTAT`	2	--	int¹		10	MN EA NS NA WA	2190
rs556339^1,2	C,F,	25870745(-)	`ACCTGG/ACATTT`	2	--	int¹		13	MN EA NS NA WA	2300
rs579996^1,2	C,F,	25871044(+)	`AGGTAG/ATTGTG`	2	--	int¹		102	NS EA PA EU CA WA NA	6686
rs633615^1,2		25872196(-)	`CTATTC/ATTTCT`	2	--	int¹		1	MN	184
rs648433^1,2	C,F,O,	25873243(+)	`TGCCAT/CGGTAA`	2	--	int¹		8	NS EA NA	736
rs651578^1,2	C,F,O,A,	25873883(-)	`GATCCA/GGTGAG`	2	--	int¹		12	EA NA WA	2028
rs717550^1,2	C,H	25855795(+)	`CACTCG/TTCTCT`	2	--	int¹		6	NA NS EA	680

About this table

HapMap Linkage Disequilibrium images for SLC17A3 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLC17A3: --

QIAGEN SeqTarget long-range PCR primers for resequencing SLC17A3

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SLC17A3 for disorders About GeneDecksing

OMIM: 611034 disorders: 232240

Human Gene Mutation Database (HGMD): SLC17A3
Human Genome Epidemiology (HuGE) Navigator: SLC17A3 (7 documents)

Export disorders and mutations for SLC17A3 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

Three Genes, Risk Score Can Facilitate Risk Prediction of Gout

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/16 PubMed articles for SLC17A3 gene, integrated from 7 sources (see all 16):
(articles sorted by number of sources associating them with SLC17A3)

A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PubMed id 9149941)^{1, 2, 3} Ruddy D.A.... Feder J.N. (1997)
NPT4, a new microsomal phosphate transporter: mutation analysis in glycogen storage disease type Ic. (PubMed id 15505377)^{1, 2, 7} Melis D.... Verheijen F. (2004)
Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)¹ Ucisik-Akkaya E....Tevfik Dorak M. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series. (PubMed id 20162743)¹ Polasek O....KolciA8 I. (2010)
Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. (PubMed id 20810651)¹ Jutabha P....Sakurai H. (2010 Nov 5)
Common variants on chromosome 6p22.1 are associated w ith schizophrenia. (PubMed id 19571809)¹ Shi J....Gejman P.V. (2009)
Common polymorphisms influencing serum uric acid leve ls contribute to susceptibility to gout, but not to coronary artery disease. (PubMed id 19890391)¹ Stark K....Hengstenberg C. (2009)
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (PubMed id 19862010)¹ Ganesh S.K....Lin J.P. (2009)
Sex and age interaction with genetic association of a therogenic uric acid concentrations. (PubMed id 20053405)¹ BrandstAotter A....Kronenberg F. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10786	HGNC: 10931	AceView: SLC17A3	Ensembl:ENSG00000124564	euGenes: HUgn10786
ECgene: SLC17A3	H-InvDB: SLC17A3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for SLC17A3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for SLC17A3 gene:
Search GeneIP for patents involving SLC17A3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SLC17A3		Antibodies for SLC17A3
	Super-pooled esiRNAs for SLC17A3		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SLC17A3		microRNA Mimics for SLC17A3
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
	feedback

	Antibodies		Cell Culture Products
	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SLC17A3
	SeqTarget long-range PCR primers for resequencing SLC17A3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SLC17A3

	GenScript Custom Purified and Recombinant Proteins Services for SLC17A3		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SLC17A3
	GenScript Custom Assay Services for SLC17A3		GenScript Custom Superior Antibodies Services for SLC17A3
	GenScript Custom overexpressing Cell Line Services for SLC17A3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in SLC17A3 promoter
	Search Chromatin IP Primers for SLC17A3
	RT² qPCR Primer Assay for SLC17A3
	Search GNC Networks for SLC17A3
	Search for Assays for microRNAs that regulate SLC17A3
	SABiosciences PCR Arrays including SLC17A3

Search Tocris compounds for SLC17A3

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Antibodies for SLC17A3
	Proteins for SLC17A3
	Lysates for SLC17A3

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

ELISAs and CLIAs for SLC17A3

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

View Random Gene

Category
GIFtS Group

The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

SLC17A3 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

Advanced Search

Export list of displayed genes

SLC17A3 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for SLC17A3 gene

Summaries
for SLC17A3 gene

Genomic Views
for SLC17A3 gene

Proteins
for SLC17A3 gene

Protein Domains/
Families
for SLC17A3 gene

Gene Function
for SLC17A3 gene

Pathways & Interactions
for SLC17A3 gene

Drugs & Compounds
for SLC17A3 gene

Transcripts
for SLC17A3 gene

Expression
for SLC17A3 gene

Orthologs
for SLC17A3 gene

Paralogs
for SLC17A3 gene

Genomic Variants
for SLC17A3 gene

Disorders & Mutations
for SLC17A3 gene

Medical News
for SLC17A3 gene

Publications
for SLC17A3 gene

External Searches for SLC17A3 gene

Genome Databases showing SLC17A3 gene

Other Databases showing SLC17A3 gene

Specialized Databases showing SLC17A3 gene

Intellectual Property
for SLC17A3 gene

Products
for SLC17A3 gene

View Random Gene

Advanced Search

Export list of displayed genes

SLC17A3 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor SLC17A3 gene

Summariesfor SLC17A3 gene

Genomic Viewsfor SLC17A3 gene

Proteinsfor SLC17A3 gene

Protein Domains/Familiesfor SLC17A3 gene

Gene Functionfor SLC17A3 gene

Pathways & Interactionsfor SLC17A3 gene

Drugs & Compoundsfor SLC17A3 gene

Transcriptsfor SLC17A3 gene

Expression for SLC17A3 gene

Orthologsfor SLC17A3 gene

Paralogsfor SLC17A3 gene

Genomic Variantsfor SLC17A3 gene

Disorders & Mutationsfor SLC17A3 gene

Medical Newsfor SLC17A3 gene

Publicationsfor SLC17A3 gene

External Searches for SLC17A3 gene

Genome Databases showing SLC17A3 gene

Other Databases showing SLC17A3 gene

Specialized Databases showing SLC17A3 gene

Intellectual Propertyfor SLC17A3 gene

Productsfor SLC17A3 gene

View Random Gene

Aliases &
Descriptions
for SLC17A3 gene

Summaries
for SLC17A3 gene

Genomic Views
for SLC17A3 gene

Proteins
for SLC17A3 gene

Protein Domains/
Families
for SLC17A3 gene

Gene Function
for SLC17A3 gene

Pathways & Interactions
for SLC17A3 gene

Drugs & Compounds
for SLC17A3 gene

Transcripts
for SLC17A3 gene

Expression
for SLC17A3 gene

Orthologs
for SLC17A3 gene

Paralogs
for SLC17A3 gene

Genomic Variants
for SLC17A3 gene

Disorders & Mutations
for SLC17A3 gene

Medical News
for SLC17A3 gene

Publications
for SLC17A3 gene

Intellectual Property
for SLC17A3 gene

Products
for SLC17A3 gene