Home
GeneCards Guide
Suite
- GeneALaCart
- GeneDecks
- GeneIP
- GeneNote
- GeneAnnot
- GeneLoc
- GeneTide
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

SMYD2 Gene

protein-coding GIFtS: 48

GC01P185129

SET and MYND domain containing 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
SET and MYND domain containing 2¹ ²		Lysine N-methyltransferase 3C² ³
KMT3C¹ ² ³		zinc finger, MYND domain containing 14²
HSKM-B¹ ² ³		MGC119305²
ZMYND14¹ ²		SET and MYND domain-containing protein 2²

External Ids:	HGNC: 20982¹	Entrez Gene: 56950²	Ensembl: ENSG00000143499⁷	UniProtKB: Q9NRG4³

Export aliases for SMYD2 gene to outside databases

Previous GC identifers: GC01P211070 GC01P211511 GC01P210842 GC01P212521 GC01P214454

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SMYD2:

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 (PubMed

16805913)).(supplied by OMIM)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SMYD2 gene promoter:
         p53   GR-beta   GR-alpha   Nkx3-1   Nkx3-1 v1   Nkx3-1 v2   Nkx3-1 v3   Nkx3-1 v4   Nkx2-2   HNF-1A
         Other transcription factors

Search SABiosciences Chromatin IP Primers for SMYD2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for SMYD2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3 Ensembl cytogenetic band: 1q32.3 HGNC cytogenetic band: 1q32.3

SMYD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SMYD2 gene location

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P185129: view genomic region (about GC identifiers)

Start:	185,129,703 bp from pter
End:	185,185,600 bp from pter
Size:	55,898 bases
Orientation:	plus strand

1 alternative location:

Chr1+ 214,454,445-214,510,474

RefSeq DNA sequence:

NC_000001.10 NT_167186.1

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: SMYD2_HUMAN, Q9NRG4 (See protein sequence)

Recommended Name: SET and MYND domain-containing protein 2

Size: 433 amino acids; 49688 Da

Secondary accessions: B2R9P9 Q4V765 Q5VSH9

Explore the universe of human proteins at neXtProt for SMYD2: NX_Q9NRG4

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_064582.2

ENSEMBL proteins:

ENSP00000409822 ENSP00000388682 ENSP00000355924

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SMYD2 OriGene Protein Over-expression Lysate: SMYD2
	GenScript Custom Purified and Recombinant Proteins Services for SMYD2
	Novus Biologicals Protein for SMYD2
	Novus Biologicals Lysates for SMYD2
	Sino Biological Recombinant Protein for SMYD2
	Browse ProSpec Recombinant Proteins

Antibodies for SMYD2:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for SMYD2
	OriGene Antibodies (see all 2): SMYD2
	GenScript Custom Superior Antibodies Services for SMYD2
	Novus Biologicals Antibodies for SMYD2
	Browse antibodies at Epitomics

Assays for SMYD2:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SMYD2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SMYD2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SMYD2 for domains About GeneDecksing

3 InterPro domains/families:

IPR002893 Znf_MYND

IPR001214 SET_dom

IPR011990 TPR-like_helical

Graphical View of Domain Structure for InterPro Entry Q9NRG4

ProtoNet protein and cluster: Q9NRG4

2 Blocks protein families:

IPB001214 Nuclear protein SET

IPB002893 Zn-finger

UniProtKB/Swiss-Prot: SMYD2_HUMAN, Q9NRG4

Similarity: Contains 1 MYND-type zinc finger

Similarity: Contains 1 SET domain

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Browse siRNA at Sigma-Aldrich Browse shRNA at Sigma-Aldrich
		OriGene 29mer shRNA kits in GFP-retroviral vector: SMYD2 OriGene shRNA RFP: SMYD2 OriGene basic RS shRNA: SMYD2 OriGene siRNA: SMYD2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SMYD2

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SMYD2
		1 SABiosciences Assays for microRNA that regulate SMYD2:
		hsa-miR-1179

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: SMYD2 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: SMYD2 OriGene untagged cDNA clones in CMV expression vector: SMYD2 OriGene 3'-UTR clone: SMYD2 Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for SMYD2
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for SMYD2

3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17353931
GO:0008270	zinc ion binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

SMYD2 for ontologies About GeneDecksing

Animal Models: 1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Smyd2):

cardiovascular system

SMYD2 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for SMYD2

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for SMYD2

5/7 Interacting proteins for SMYD2 (Q9NRG4¹) via UniProtKB, MINT, and/or STRING (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AKAP11	Q9UKA4¹	EBI-1055671,EBI-1049491
AXIN1	O15169¹	EBI-1055671,EBI-710484
CDC37	Q16543¹	EBI-1055671,EBI-295634
EPB41L3	Q9Y2J2¹	EBI-1055671,EBI-310986
GSK3B	P49841¹	EBI-1055671,EBI-373586

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SMYD2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Browse siRNA at Sigma-Aldrich Browse shRNA at Sigma-Aldrich
		OriGene 29mer shRNA kits in GFP-retroviral vector: SMYD2 OriGene shRNA RFP: SMYD2 OriGene basic RS shRNA: SMYD2 OriGene siRNA: SMYD2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SMYD2

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SMYD2
		1 SABiosciences Assays for microRNA that regulate SMYD2:
		hsa-miR-1179

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: SMYD2 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: SMYD2 OriGene untagged cDNA clones in CMV expression vector: SMYD2 OriGene 3'-UTR Clone: SMYD2 Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for SMYD2

Primers:		OriGene genome-wide validated SYBR primer pairs: SMYD2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for SMYD2: PPH09766A

REFSEQ mRNAs for SMYD2 gene:

NM_020197.2

Additional cDNA sequence:

AF070592.1 AF226053.1 AK090571.1 AK091590.1 AK098683.1 AK313868.1 BC017080.2 BC028104.1

BC039890.1 BC057793.1 BC068511.1 BC098133.1 BC098276.1 BC098335.1 CR589978.1 CR592315.1

CR613242.1 CR617804.1 CR622801.1

14 DOTS entries:

DT.446799 DT.95183994 DT.100032982 DT.91800781 DT.100819009 DT.100033037 DT.40250753 DT.100819010

DT.91924949 DT.97858902 DT.100809597 DT.75140314 DT.91692734 DT.444352

24/213 AceView cDNA sequences (see all 213):

R88886 H98065 CR622801 BC028104 BC017080 AI708404 CR613242 AK098683

AI627479 BM739135 CR589978 AW519313 CR592315 BM740370 CA434890 CF552077

AI692922 AA804764 AI377234 CA411809 CR617804 CA313122 BM466219 BC039890

highest scoring ESTs for SMYD2:

AA013448 AA252060 AA455686 AA505984 AA580554 AA581289 AA804764 AA812663 AA812773 AA897260

Unigene Cluster for SMYD2:

SET and MYND domain containing 2

Hs.66170 [show with all ESTs]

Unigene Representative Sequence: BC068511

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SMYD2 (see all 6)

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10	^	11a	·	11b	^	12a	·	12b
SP1:															-										-				-
SP2:															-								-		-		-		-
SP3:					-										-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for SMYD2
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000416415 ENST00000415093 ENST00000471645(uc009xdj.2 uc010ptw.1)

ENST00000460580 ENST00000484459 ENST00000366957 ENST00000491455(uc010ptx.1 uc009xdl.1)

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

SMYD2 expression in normal and diseased human tissues

¹ / ² / ³

4 probe-sets matching SMYD2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
212922_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI809870	0.80	1.00	0.91	1
212921_at²^{, 3}	U133-A	1	0.36	1.00	--	--	AF070592	0.80	1.00	0.91	1
212922_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
212921_at²	U133Plus2	1	0.36	1.00	--	--	--	--	--	--	--

About this table
Data from Genenote (Publications) and GNF BioGPS
About these images

SMYD2 gene electronic northern expression

About these images

CGAP SAGE TAG: CCTCTTGTAA

SOURCE GeneReport for Unigene cluster: Hs.66170

Expression variation in blood from EXPOLDB for SMYD2

Primers:		OriGene genome-wide validated SYBR primer pairs: SMYD2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for SMYD2: PPH09766A

SABiosciences Custom PCR Arrays for SMYD2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SMYD2 gene from 5/10 species (see all 10)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SMYD2¹	--	SET and MYND domain containing 2	88.66(n) 93.06(a)	480026 XM_537149.2 XP_537149.2
cow (Bos taurus)	SMYD2¹	--	SET and MYND domain containing 2	93.07(n) 96.77(a)	615229 NM_001076364.1 NP_001069832.1
rat (Rattus norvegicus)	Smyd2¹	--	SET and MYND domain containing 2	87.45(n) 93.76(a)	289372 XM_213972.4 XP_213972.2
mouse (Mus musculus)	Smyd2^{1 , 5}	1 (95.03 cM)⁵	SET and MYND domain containing 2^{1, 5}	87.37(n)¹ 93.53(a)¹	226830¹ NM_026796.1¹ NP_081072.1¹ AI847158⁵ AK003853⁵ (see all 17)
chicken (Gallus gallus)	SMYD2¹	--	SET and MYND domain containing 2	80.83(n) 86.37(a)	421361 XM_419420.2 XP_419420.1

About this table Species with no ortholog for SMYD2

ENSEMBL Gene Tree for SMYD2 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SMYD2 gene

SMYD4² SMYD1² SMYD3²

SMYD2 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs4179^1,2	C,F	214510382(-)	`AAAACTCTG/- TCTGT`	1	--	ut3¹		5	EU NA EA	344
rs867444^1,2	C,F,A,	214502160(+)	`TCGGCT/CGGGGT`	1	--	int¹		11	EA NA NS WA	690
rs867445^1,2	C,F,A,	214502230(+)	`TGCAGC/GCAGTC`	1	--	int¹		12	NS EA NA WA	970
rs867446^1,2	C,F,A,	214502322(+)	`GGCTGG/TGAGCA`	1	--	int¹		7	NS EA NA WA	542
rs870117^1,2	C,F,O,A,H,	214505752(+)	`GCGGAT/CACTGG`	1	--	int¹		14	NS EA NA WA	2246
rs870118^1,2	C,F,	214505689(+)	`GCACTG/CCTCCC`	1	--	int¹		7	NS EA NA	486
rs904321^1,2	C,F,O,A,H,	214506550(-)	`ACACTC/GTAGGA`	1	--	int¹		13	NA EA NS WA	850
rs955920^1,2	C,F,O,A,H,	214464309(-)	`ATTCAC/TGGAAT`	1	--	int¹		13	NA NS EA WA	862
rs958304^1,2	C,F,O,A,H,	214474241(+)	`tccctC/Ttgtac`	1	--	int¹		11	MN NS EA NA WA	868
rs985853^1,2	C,F,A,	214459654(-)	`taaaaT/Attttt`	1	--	int¹		8	NS EA NA WA	508

About this table

HapMap Linkage Disequilibrium images for SMYD2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SMYD2: --

QIAGEN SeqTarget long-range PCR primers for resequencing SMYD2

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SMYD2 for disorders About GeneDecksing

OMIM: 610663

Human Genome Epidemiology (HuGE) Navigator: SMYD2 (1 document)

Export disorders and mutations for SMYD2 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/14 PubMed articles for SMYD2 gene, integrated from 7 sources (see all 14):
(articles sorted by number of sources associating them with SMYD2)

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)¹ Trynka G....Wijmenga C. (2009)
Overexpression of SMYD2 relates to tumor cell prolife ration and malignant outcome of esophageal squamous cell carcinoma. (PubMed id 19423649)¹ Komatsu S....Inazawa J. (2009)
The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. (PubMed id 18065756)¹ Abu-Farha M....Figeys D. (2008)
Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)¹ Ewing R.M.... Figeys D. (2007)
Repression of p53 activity by Smyd2-mediated methylation. (PubMed id 17108971)¹ Huang J.... Berger S.L. (2006)
Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. (PubMed id 16805913)¹ Brown M.A....Tucker P.W. (2006)
JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats. (PubMed id 15743541)¹ Kobayashi H....Sugihara K. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 56950	HGNC: 20982	AceView: SMYD2	Ensembl:ENSG00000143499	euGenes: HUgn56950
ECgene: SMYD2	H-InvDB: SMYD2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for SMYD2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for SMYD2 gene:
Search GeneIP for patents involving SMYD2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Browse siRNAs at Sigma-Aldrich		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Browse shRNAs at Sigma-Aldrich		Browse microRNA Mimics at Sigma-Aldrich
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
	feedback

	Antibodies		Cell Culture Products
	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of SMYD2
	SeqTarget long-range PCR primers for resequencing SMYD2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for SMYD2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of SMYD2

	GenScript Custom Purified and Recombinant Proteins Services for SMYD2		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SMYD2
	GenScript Custom Assay Services for SMYD2		GenScript Custom Superior Antibodies Services for SMYD2
	GenScript Custom overexpressing Cell Line Services for SMYD2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Antibodies & Assays for SMYD2

	Regulatory tfbs in SMYD2 promoter
	Search Chromatin IP Primers for SMYD2
	RT² qPCR Primer Assay for SMYD2
	GNC Network for SMYD2
	Assays for microRNAs that regulate SMYD2
	SABiosciences Custom PCR Arrays for SMYD2

Search Tocris compounds for SMYD2

	Proteins and Antibodies for SMYD2
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Antibodies for SMYD2
	Proteins for SMYD2
	Lysates for SMYD2

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

ELISAs and CLIAs for SMYD2

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

View Random Gene

Category
GIFtS Group

The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

SMYD2 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

Advanced Search

Export list of displayed genes

SMYD2 Gene

protein-coding GIFtS: 48

Aliases &
Descriptions
for SMYD2 gene

Summaries
for SMYD2 gene

Genomic Views
for SMYD2 gene

Proteins
for SMYD2 gene

Protein Domains/
Families
for SMYD2 gene

Gene Function
for SMYD2 gene

Pathways & Interactions
for SMYD2 gene

Drugs & Compounds
for SMYD2 gene

Transcripts
for SMYD2 gene

Expression
for SMYD2 gene

Orthologs
for SMYD2 gene

Paralogs
for SMYD2 gene

Genomic Variants
for SMYD2 gene

Disorders & Mutations
for SMYD2 gene

Medical News
for SMYD2 gene

Publications
for SMYD2 gene

External Searches for SMYD2 gene

Genome Databases showing SMYD2 gene

Other Databases showing SMYD2 gene

Specialized Databases showing SMYD2 gene

Intellectual Property
for SMYD2 gene

Products
for SMYD2 gene

View Random Gene

Advanced Search

Export list of displayed genes

SMYD2 Gene

protein-coding GIFtS: 48

Aliases & Descriptionsfor SMYD2 gene

Summariesfor SMYD2 gene

Genomic Viewsfor SMYD2 gene

Proteinsfor SMYD2 gene

Protein Domains/Familiesfor SMYD2 gene

Gene Functionfor SMYD2 gene

Pathways & Interactionsfor SMYD2 gene

Drugs & Compoundsfor SMYD2 gene

Transcriptsfor SMYD2 gene

Expression for SMYD2 gene

Orthologsfor SMYD2 gene

Paralogsfor SMYD2 gene

Genomic Variantsfor SMYD2 gene

Disorders & Mutationsfor SMYD2 gene

Medical Newsfor SMYD2 gene

Publicationsfor SMYD2 gene

External Searches for SMYD2 gene

Genome Databases showing SMYD2 gene

Other Databases showing SMYD2 gene

Specialized Databases showing SMYD2 gene

Intellectual Propertyfor SMYD2 gene

Productsfor SMYD2 gene

View Random Gene

Aliases &
Descriptions
for SMYD2 gene

Summaries
for SMYD2 gene

Genomic Views
for SMYD2 gene

Proteins
for SMYD2 gene

Protein Domains/
Families
for SMYD2 gene

Gene Function
for SMYD2 gene

Pathways & Interactions
for SMYD2 gene

Drugs & Compounds
for SMYD2 gene

Transcripts
for SMYD2 gene

Expression
for SMYD2 gene

Orthologs
for SMYD2 gene

Paralogs
for SMYD2 gene

Genomic Variants
for SMYD2 gene

Disorders & Mutations
for SMYD2 gene

Medical News
for SMYD2 gene

Publications
for SMYD2 gene

Intellectual Property
for SMYD2 gene

Products
for SMYD2 gene