Aliases &
Descriptions
for SNORD73A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| small nucleolar RNA, C/D box 73A1 2 | | U732 | | U73a1 2 | | v-fos transformation effector protein3 | | RNU73A1 2 | | FTE13 | | RNA, U73 small nucleolar1 | | MFTL3 | | RNU732 | | Fte-13 |
Export aliases for SNORD73A gene to outside databasesPrevious GC identifer: GC04P152244 |
Summaries
for SNORD73A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RS3A_HUMAN, P61247Function: May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity)
|
Genomic Views
for SNORD73A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SNORD73A gene promoter:
E47 GR-alpha GATA-1 CUTL1 GATA-2 Chx10 E2F E2F-2 E2F-5 E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SNORD73A
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q31.3 Ensembl cytogenetic band: 4q31.3 HGNC cytogenetic band: 4q31.3SNORD73A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P152025: view genomic region
(about GC identifiers)
Start:
|
152,020,725 bp from pter |
End:
|
152,025,804 bp from pter |
Size:
|
5,080 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr4+ 147,750,299-147,750,363 |
|
Proteins
for SNORD73A gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: RS3A_HUMAN, P61247 (See
protein sequence)Recommended Name: 40S ribosomal protein S3a Size: 264 amino acids; 29945 Da
Subunit: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit.The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a mRNP granule complex, at least composedof ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2,ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 anduntranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3 (By similarity)
Subcellular location: Cytoplasm. Nucleus (By similarity). Note=Localized in cytoplasmic mRNP granules containinguntranslated mRNAs
Secondary accessions: B2R4D4 P33443 P49241Explore the universe of human proteins at neXtProt for SNORD73A: NX_P61247
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
ENSEMBL proteins: ENSP00000346050 ENSP00000422994 ENSP00000425024 ENSP00000421770 ENSP00000425978 ENSP00000421277 ENSP00000423953 ENSP00000421776 ENSP00000421457 ENSP00000424547 ENSP00000425508 ENSP00000426282 ENSP00000426466
Human Recombinant Proteins
5/8 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 8): About this table
SNORD73A for ontologies About GeneDecksing
Antibodies for SNORD73A:
Assays for SNORD73A: |
Protein
Domains/
Families
for SNORD73A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SNORD73A for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P61247ProtoNet protein and cluster: P61247 UniProtKB/Swiss-Prot: RS3A_HUMAN, P61247Similarity: Belongs to the ribosomal protein S3Ae family |
Gene Function
for SNORD73A gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: RS3A_HUMAN, P61247Function: May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity)
3 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
SNORD73A for ontologies About GeneDecksing
|
Pathways & Interactions
for SNORD73A gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for SNORD73A
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNORD73A
5/277 Interacting proteins for SNORD73A (P612471, 2 ENSP000003460503) via UniProtKB, MINT, and/or STRING (see all 277)About this table
5 Gene Ontology (GO) biological process terms (GO ID links to tree view): About this table
SNORD73A for ontologies About GeneDecksing
|
Drugs & Compounds
for SNORD73A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for SNORD73A
|
Transcripts
for SNORD73A gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
24/6227 AceView cDNA sequences (see all 6227): BE728718 BQ957553 BG163401 BX424384 BQ020502 BE293407 BE729074 AI884605 BE391504 AI744098 BM801346 AW515902 BE744279 AW593066 BM452018 BQ068538 BE378619 BM311094 BU183195 BP373781 BX464760 BG105104 BU839577 BQ056502
 highest scoring ESTs for SNORD73A:AA228479 BQ432548 CN315189 AA078965 AA173726 AA181374 AA197205 AA224924 AA508669 AA599471
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SNORD73A (see all 7)
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 |
|---|
|
| SP1: | | | | | - | | - | | | | | | | | - | | | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | | | - | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | - | | - | | - | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for SNORD73A
14 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000274065(uc003ilz.2) ENST00000509736 ENST00000507485(uc003ima.1 uc011cie.1)
ENST00000505243 ENST00000514682 ENST00000515818 ENST00000503002 ENST00000512690
ENST00000508783 ENST00000512797 ENST00000507327 ENST00000515792 ENST00000506126
ENST00000510993
|
Expression
for SNORD73A gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| SNORD73A expression in normal and diseased human tissues
/ 3 Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SABiosciences Custom PCR Arrays for SNORD73A
|
Orthologs
for SNORD73A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SNORD73A gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
baker's yeast
(Saccharomyces cerevisiae) |
RPS1B(YML063W)4 |
13(146482-147249) |
Ribosomal protein 10 (rp10) of the small (40S) subunit; more |
-- |
854939 NP_013648.1 |
About this table Species with no ortholog for SNORD73A
ENSEMBL Gene Tree for SNORD73A (if available) |
Paralogs
for SNORD73A gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for SNORD73A gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SNORD73A
1 CNV: 34438 |
Disorders & Mutations
for SNORD73A gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SNORD73A for disorders About GeneDecksing
OMIM: 603568
Export disorders and mutations for SNORD73A gene to outside databases
|
Medical News
for SNORD73A gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for SNORD73A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/20 PubMed articles for SNORD73A gene, integrated from 7 sources (see all 20):
(articles sorted by number of sources associating them with SNORD73A)- A novel snoRNA (U73) is encoded within the introns of the human and mouse ribosomal protein S3a genes. (PubMed id 9573378)1, 3 Rebane A....Metspalu A. (1998)
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. (PubMed id 19007248)2 Wang B.... Korner R. (2008)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Molecular composition of IMP1 ribonucleoprotein granules. (PubMed id 17289661)2 Joeson L.... Nielsen F.C. (2007)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
|
External Searches for SNORD73A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SNORD73A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SNORD73A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SNORD73A gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SNORD73A gene:
Search GeneIP for patents involving SNORD73A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SNORD73A gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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