Aliases &
Descriptions
for SOD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| superoxide dismutase 2, mitochondrial1 2 | | indophenoloxidase B2 | | MNSOD2 5 | | superoxide dismutase [Mn], mitochondrial2 | | MVCD62 5 | | manganese-containing superoxide dismutase2 | | IPOB2 | | mangano-superoxide dismutase2 | | Mn superoxide dismutase2 | | EC 1.15.1.13 |
Export aliases for SOD2 gene to outside databasesPrevious GC identifers: GC06M159539 GC06M159973 GC06M160009 GC06M160012 GC06M160070 GC06M160020 GC06M160102 |
Summaries
for SOD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SOD2:
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that formsa homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidativephosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have beenassociated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternatetranscriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq)
UniProtKB/Swiss-Prot: SODM_HUMAN, P04179Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Gene Wiki entry for SOD2 |
Genomic Views
for SOD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SOD2 gene promoter:
STAT1alpha STAT1beta STAT1 AP-1 FOXO1a c-Fos c-Jun IRF-1 p53 AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for SOD2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for SOD2  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q25.3 Ensembl cytogenetic band: 6q25.3 HGNC cytogenetic band: 6q25SOD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M157570: view genomic region
(about GC identifiers)
Start:
|
157,570,584 bp from pter |
End:
|
157,584,704 bp from pter |
Size:
|
14,121 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr6- 160,100,148-160,114,353 |
RefSeq DNA sequence:- NC_000006.11 NT_025741.15
|
Proteins
for SOD2 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: SODM_HUMAN, P04179 (See
protein sequence)Recommended Name: Superoxide dismutase [Mn], mitochondrial precursor Size: 222 amino acids; 24722 Da
Cofactor: Binds 1 manganese ion per subunit
Subunit: Homotetramer
Subcellular location: Mitochondrion matrix
PDB structures from  and Proteopedia  :1AP5 (3D)
1AP6 (3D)
1EM1 (3D)
1JA8 (3D)
1LUV (3D)
1LUW (3D)
1MSD (3D)
1N0J (3D)
1N0N (3D)
1PL4 (3D)
1PM9 (3D)
1QNM (3D)
1SZX (3D)
1VAR (3D)
1XDC (3D)
1XIL (3D)
1ZSP (3D)
1ZTE (3D)
1ZUQ (3D)
2ADP (3D)
2ADQ (3D)
2GDS (3D)
2P4K (3D)
2QKA (3D)
2QKC (3D)
3C3S (3D)
3C3T (3D)
Secondary accessions: B2R7R1 P78434 Q16792 Q5TCM1 Q96EE6 Q9P2Z3Explore the universe of human proteins at neXtProt for SOD2: NX_P04179
Post-translational modifications:
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity1
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (3 alternative transcripts):
NP_000627.2 NP_001019636.1 NP_001019637.1
ENSEMBL proteins: ENSP00000337127 ENSP00000404804 ENSP00000406713 ENSP00000356022 ENSP00000356021
Human Recombinant Proteins
5 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
SOD2 for ontologies About GeneDecksing
Antibodies for SOD2:
Assays for SOD2: |
Protein
Domains/
Families
for SOD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SOD2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P04179ProtoNet protein and cluster: P04179 1 Blocks protein family: IPB001189 Manganese and iron superoxide dismutase
UniProtKB/Swiss-Prot: SODM_HUMAN, P04179Similarity: Belongs to the iron/manganese superoxide dismutase family |
Gene Function
for SOD2 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: SODM_HUMAN, P04179Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systemsCatalytic activity: 2 superoxide + 2 H(+) = O(2) + H(2)O(2)Enzyme Number (IUBMB): EC 1.15.1.1
Genatlas biochemistry entry for SOD2:manganese superoxide dismutase 2,mitochondrial,catabolic pathway of activated oxygen species,free radicaldetoxification,susceptibility factor for non familial idiopathy dilated cardiomyopathy in Japanese5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6): About this table
SOD2 for ontologies About GeneDecksing
Animal Models: 15/22 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Sod2) (see all 22):
SOD2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SOD2 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SOD2 for pathways About GeneDecksing
1  Millipore Pathway for SOD2
3  Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for SOD2
2  Kegg Pathways (Kegg details for SOD2):
SABiosciences Pathway-Focused PCR Arrays including SOD2 (see all 8): PAHS-003A PAHS-050A
Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for SOD2
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SOD2
5/11 Interacting proteins for SOD2 (ENSP000003371273 P041791) via UniProtKB, MINT, and/or STRING (see all 11)About this table
5/50 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 50): About this table
SOD2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SOD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
SOD2 for compounds About GeneDecksing
 Browse Tocris compounds for SOD2
10/144  Novoseek chemical compound relationships for SOD2 gene (see all 144)
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| manganese superoxide |
99.1 |
2165 |
7856748 (7), 11207049 (7), 16365243 (6), 9081096 (5) (see all 99) |
| superoxide |
91.8 |
911 |
18247479 (4), 2230537 (4), 7969912 (4), 10529750 (3) (see all 99) |
| zinc superoxide |
84.7 |
77 |
7856748 (6), 9989524 (2), 10692109 (2), 15258423 (2) (see all 44) |
| oxygen |
79.1 |
274 |
11536448 (4), 1385428 (3), 7914182 (2), 11159050 (2) (see all 99) |
| manganese |
76.3 |
184 |
1550052 (6), 10521117 (6), 12950012 (4), 12215453 (3) (see all 90) |
| h2o2 |
73.6 |
158 |
16114557 (5), 9535218 (3), 10919671 (3), 19306099 (3) (see all 84) |
| copper |
64.4 |
150 |
7856748 (6), 14531733 (4), 1793616 (3), 9989524 (2) (see all 85) |
| peroxynitrite |
63.9 |
44 |
11152462 (5), 9603906 (4), 9425011 (2), 19917352 (2) (see all 20) |
| n acetylcysteine |
60.1 |
27 |
11709424 (2), 18829485 (2), 9518260 (1), 18281048 (1) (see all 16) |
| 3-nitrotyrosine |
56.4 |
10 |
16895800 (3), 14656937 (2), 9848095 (1), 16765071 (1) (see all 5) |
About this table
3 PharmGKB drug compound relationships for SOD2 geneAbout this table
|
Transcripts
for SOD2 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for SOD2 gene (3 alternative transcripts): NM_000636.2 NM_001024465.1 NM_001024466.1 Additional cDNA sequence: AK296809.1 AK304766.1 AK313082.1 AL050388.1 AY280718.1 AY280719.1 AY280720.1 AY280721.1 BC012423.1 BC016015.1 BC016934.1 BC035422.1 BC041951.1 BT006967.1 CR626136.1 DQ003134.1 M31163.1 M36693.1 X07834.1 X14322.1 X15132.1 X59445.1 Y00472.1 Y00985.1 24/56 DOTS entries (see all 56): DT.101985421 DT.95350909 DT.420015 DT.97856570 DT.91763736 DT.95189349 DT.100828782 DT.100828766 DT.100828787 DT.121326891 DT.121326878 DT.121327136 DT.121327061 DT.121326777 DT.86851629 DT.100692392 DT.100828778 DT.121327128 DT.87001758 DT.100828790 DT.100688162 DT.100828793 DT.99947916 DT.121327054 24/538 AceView cDNA sequences (see all 538): AA343663 AW794755 AA977637 AU077038 AU280001 AI473383 BF060664 BQ691900 BM768463 BQ719652 BP350474 CA446393 BU682373 F04037 AI459858 BQ009368 BQ950610 AI288966 AA363542 CA306232 AL135472 BU621731 AA602843 BU195882
 highest scoring ESTs for SOD2:X07834 AA011434 AA317108 AA343610 AA363542 AA370060 AA370365 AA370378 AA370601 AA370844 Unigene Cluster for SOD2: Superoxide dismutase 2, mitochondrial Hs.487046 [show with all ESTs]Unigene Representative Sequence: BC041951
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SOD2 (see all 8)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for SOD2
5 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000337404(uc003qsi.1 uc011efu.1 uc011efv.1) ENST00000444946
ENST00000452684(uc003qsj.2) ENST00000367055(uc003qsf.3 uc003qsg.2)
ENST00000367054(uc003qsh.2)
|
Expression
for SOD2 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| SOD2 expression in normal and diseased human tissues
1 / 2 / 3 12 probe-sets matching SOD2 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 73312_s_at2, 3
|
U95-E |
2 |
1.00 |
0.91 |
0.96 |
1.44 |
AI984828 |
0.60 |
1.00 |
0.82 |
1 |
| 34666_at2, 3
|
U95-A |
1 |
0.81 |
1.00 |
0.97 |
0.79 |
X07834 |
1.00 |
1.00 |
1.00 |
1 |
| 45237_at2, 3
|
U95-B |
1 |
0.56 |
1.00 |
0.97 |
1.29 |
AA142976 |
0.60 |
1.00 |
0.82 |
1 |
| 86491_at2, 3
|
U95-D |
2 |
0.50 |
0.62 |
0.41 |
0.49 |
AW007472 |
0.40 |
1.00 |
0.76 |
1 |
| 215223_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
W46388 |
0.60 |
1.00 |
0.82 |
1 |
| 216841_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
X15132 |
0.80 |
1.00 |
0.91 |
1 |
| 221477_s_at2, 3
|
U133-A |
1 |
0.64 |
1.00 |
-- |
-- |
BF575213 |
0.20 |
1.00 |
0.72 |
1 |
| 215078_at2, 3
|
U133-A |
1 |
0.46 |
1.00 |
-- |
-- |
AL050388 |
0.80 |
1.00 |
0.91 |
1 |
| 215223_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 216841_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 221477_s_at2
|
U133Plus2 |
1 |
0.64 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 215078_at2
|
U133Plus2 |
1 |
0.46 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
SOD2 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GTCTTAAAGT
SOURCE GeneReport for Unigene cluster: Hs.487046
Expression variation in blood from EXPOLDB for SOD2 SABiosciences Expression via Pathway-Focused PCR Arrays including SOD2 (see all 8): PAHS-003A PAHS-050A
|
Orthologs
for SOD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SOD2 gene from 5/25 species (see all 25)
About this table Species with no ortholog for SOD2
ENSEMBL Gene Tree for SOD2 (if available) |
Paralogs
for SOD2 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for SOD2 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 6 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for SOD2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SOD2
1 CNV: 3647
1 Indel: 11272 | | QIAGEN SeqTarget long-range PCR primers for resequencing SOD2 |
|
Disorders & Mutations
for SOD2 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SOD2 for disorders About GeneDecksing
OMIM: 147460 disorders: 612634 UniProtKB/Swiss-Prot: SODM_HUMAN, P04179
Genetic variation in SOD2 is associated with susceptibility to microvascular complications of diabetes type 6(MVCD6) [MIM:612634]. These are pathological conditions that develop in numerous tissues and organs as a consequenceof diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, anddiabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It ischaracterized by vascular permeability and increased tissue ischemia and angiogenesis
10/92 Novoseek disease relationships for SOD2 gene (see all 92)
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| necrosis |
58.7 |
129 |
20514411 (4), 1960995 (3), 2406241 (2), 2222450 (2) (see all 75) |
| tumors |
54.5 |
432 |
12469139 (8), 10919671 (6), 1988135 (6), 7780953 (4) (see all 99) |
| amyotrophic lateral sclerosis |
49 |
18 |
7985495 (2), 9452823 (2), 7699393 (1), 7719145 (1) (see all 12) |
| cancer |
47.5 |
158 |
19074833 (5), 19405048 (4), 19467856 (4), 9926924 (3) (see all 87) |
| cell damage |
42.9 |
10 |
11729237 (3), 7524486 (1), 20107204 (1), 8360707 (1) (see all 7) |
| neurodegenerative diseases |
42 |
4 |
10762167 (1), 8334770 (1), 12618592 (1) |
| neurodegeneration |
40.1 |
3 |
17251466 (1), 16485861 (1), 14681883 (1) |
| shock |
35.5 |
46 |
15128298 (2), 1337859 (2), 7514009 (2), 8144583 (1) (see all 31) |
| breast cancer |
35.1 |
148 |
15386537 (5), 15184255 (5), 16945136 (4), 17965603 (4) (see all 49) |
| merrf |
34.2 |
3 |
11403514 (1), 11907800 (1) |
About this table
2 PharmGKB disease relationships for SOD2 geneAbout this table
Human Gene Mutation Database (HGMD): SOD2
Genetic Association Database (GAD): SOD2
Human Genome Epidemiology (HuGE) Navigator: SOD2 (288 documents)
Export disorders and mutations for SOD2 gene to outside databases
|
Medical News
for SOD2 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| |
Publications
for SOD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/1539 PubMed articles for SOD2 gene, integrated from 7 sources (see all 1539):
(articles sorted by number of sources associating them with SOD2)- The polymorphism of manganese superoxide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients. (PubMed id 12624725)1, 2, 4, 7 Nomiyama T....Kawamori R. (2003)
- Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells. (PubMed id 1988135)1, 2, 7 St Clair D.K. and Holland J.C. (1991)
- Polymorphism in the manganese superoxide dismutase (MnSOD) gene and risk of breast cancer in young women. (PubMed id 15883815)1, 4, 7 Bergman M....Wingren S. (2005)
- Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland). (PubMed id 12948282)1, 4, 7 Woodson K....Albanes D. (2003)
- Genetic polymorphism of manganese superoxide dismutase (MnSOD) and breast cancer susceptibility. (PubMed id 15386537)1, 4, 7 Kocabas N.A....Karakaya A.E. (2005)
- Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis. (PubMed id 16157826)1, 4, 7 Stickel F....Schuppan D. (2005)
- Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk. (PubMed id 11323405)1, 4, 7 Mitrunen K....Hirvonen A. (2001)
- Manganese superoxide dismutase gene polymorphism (V16A) is associated with stages of albuminuria in Korean type 2 diabetic patients. (PubMed id 16324912)1, 4, 7 Lee S.J....Kim T.W. (2006)
- Oxidative stress-related gene polymorphism and the risk of preeclampsia. (PubMed id 15734083)1, 4, 7 Kim Y.J....Pang M.G. (2005)
- Manganese superoxide dismutase polymorphism, plasma antioxidants, cigarette smoking, and risk of breast cancer. (PubMed id 15184255)1, 4, 7 Tamimi R.M....Hunter D.J. (2004)
|
External Searches for SOD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SOD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SOD2 gene
(According to HUGE)
About This Section
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Specialized Databases showing SOD2 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| ATLAS Chromosomes in Cancer entry for SOD2 | Genetics and Cytogenetics in Oncology and Haematology | | NIEHS-SNPs | http://egp.gs.washington.edu/data/sod2/ | | SHMPD | http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=SOD2 | | Wikipedia | http://en.wikipedia.org/wiki/Superoxide_dismutase |
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| Patent Information for SOD2 gene:
Search GeneIP for patents involving SOD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SOD2 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
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