Aliases &
Descriptions
for SPHK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| sphingosine kinase 11 2 | | SPHK1 2 3 | | SPK 12 3 | | SK 12 3 | | SPK3 | | EC 2.7.1.913 |
Export aliases for SPHK1 gene to outside databasesPrevious GC identifers: GC17U990140 GC17P077371 GC17P074843 GC17P074977 GC17P071890 GC17P074380 |
Summaries
for SPHK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SPHK1:
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions.Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974).Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzesthe phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibitcellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430)and serum.(supplied by OMIM)
UniProtKB/Swiss-Prot: SPHK1_HUMAN, Q9NYA1Function: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator withboth intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, butnot other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, orphosphatidylinositol
Gene Wiki entry for SPHK1 |
Genomic Views
for SPHK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPHK1 gene promoter:
NF-kappaB1 AP-1 c-Jun c-Fos Sp1 STAT5A NF-kappaB NF-E2 NF-E2 p45 E2F-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPHK1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for SPHK1  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.2 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.2SPHK1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P069809: view genomic region
(about GC identifiers)
Start:
|
69,809,173 bp from pter |
End:
|
69,812,424 bp from pter |
Size:
|
3,252 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr17+ 74,380,690-74,383,941 |
RefSeq DNA sequence:- NC_000017.10 NT_010783.15
|
Proteins
for SPHK1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: SPHK1_HUMAN, Q9NYA1 (See
protein sequence)Recommended Name: Sphingosine kinase 1 Size: 384 amino acids; 42518 Da
Cofactor: Magnesium
Subunit: Interacts with ACY1 (By similarity). Binds to calmodulin. Interacts with SPHKAP
Miscellaneous: Sphingosine 1-phosphate stimulates TRAF2 E3 ubiquitin ligase activity, and promotes activation ofNF-kappa-B in response to TNF signaling
Secondary accessions: Q8N632 Q9HD92 Q9NY70 Q9NYL3Alternative splicing: 2 isoforms: Q9NYA1-1 Q9NYA1-2 Explore the universe of human proteins at neXtProt for SPHK1: NX_Q9NYA1
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (4 alternative transcripts):
NP_001136073.1 NP_001136074.1 NP_068807.2 NP_892010.2
ENSEMBL proteins: ENSP00000313681 ENSP00000376285
Human Recombinant Proteins
5/8 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 8): About this table
SPHK1 for ontologies About GeneDecksing
Antibodies for SPHK1:
Assays for SPHK1: |
Protein
Domains/
Families
for SPHK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPHK1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NYA1ProtoNet protein and cluster: Q9NYA1 UniProtKB/Swiss-Prot: SPHK1_HUMAN, Q9NYA1Similarity: Contains 1 DAGKc domain |
Gene Function
for SPHK1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: SPHK1_HUMAN, Q9NYA1Function: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator withboth intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, butnot other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, orphosphatidylinositolCatalytic activity: ATP + sphinganine = ADP + sphinganine 1-phosphateCatalytic activity: ATP + sphingosine = ADP + sphingosine 1-phosphateBiophysicochemical properties: Kinetic parameters: KM=14 uM for sphingosine; KM=20 uM for dihydrosphingosine; KM=77 uMfor ATP; pH dependence: Optimum pH is 7.4;Enzyme Number (IUBMB): EC 2.7.1.91
5/10 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 10): About this table
SPHK1 for ontologies About GeneDecksing
Animal Models: 10 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Sphk1):
SPHK1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SPHK1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SPHK1 for pathways About GeneDecksing
2  Millipore Pathways for SPHK1
5/8  Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for SPHK1 (see all 8)
5  Kegg Pathways (Kegg details for SPHK1):
SABiosciences Pathway-Focused PCR Arrays including SPHK1 (see all 5): PAHS-015A PAHS-024A
Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for SPHK1
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPHK1
5/36 Interacting proteins for SPHK1 (Q9NYA11, 2 ENSP000003136813) via UniProtKB, MINT, and/or STRING (see all 36)About this table
5/36 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 36): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001934 | positive regulation of protein phosphorylation |
IEA | -- | | GO:0001956 | positive regulation of neurotransmitter secretion |
IEA | -- | | GO:0006457 | protein folding |
TAS | -- | | GO:0006665 | sphingolipid metabolic process |
TAS | -- | | GO:0006670 | sphingosine metabolic process |
IDA | -- |
About this table
SPHK1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SPHK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
SPHK1 for compounds About GeneDecksing
 Compounds for SPHK1 available from Tocris Bioscience
| Compound | Action |
CAS
number |
|---|
| SKI II | Selective non-lipid inhibitor of sphingosine kinase; antitumor | [312636-16-1] |
About this table
10/25  Novoseek chemical compound relationships for SPHK1 gene (see all 25)
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sphingosine |
97.7 |
499 |
16281067 (6), 18620522 (6), 17643421 (6), 14532121 (4) (see all 99) |
| n,n-dimethylsphingosine |
93.7 |
32 |
15302883 (2), 11418646 (2), 15848761 (1), 15265705 (1) (see all 14) |
| ceramide |
83.9 |
68 |
16357178 (5), 16281067 (4), 19240026 (4), 19765607 (3) (see all 22) |
| sphinganine 1-phosphate |
80.4 |
5 |
18644793 (1), 16278291 (1), 16529909 (1) |
| ceramides |
55.1 |
1 |
18283525 (1) |
| lipid |
50.8 |
35 |
19782042 (2), 18638570 (1), 12954646 (1), 15265705 (1) (see all 20) |
| phosphatidylserine |
35.9 |
4 |
10751414 (1), 19782042 (1) |
| camptothecin |
32.8 |
7 |
16357178 (3), 16516161 (3) |
| phosphatidylinositol |
31.4 |
2 |
19325137 (1), 11418646 (1) |
| phorbol |
28.5 |
1 |
20236935 (1) |
About this table
|
Transcripts
for SPHK1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for SPHK1 gene (4 alternative transcripts): NM_001142601.1 NM_001142602.1 NM_021972.3 NM_182965.2 Additional cDNA sequence: AF200328.1 AF238083.1 AF266756.1 AJ245504.1 AK022402.1 AK023393.1 AK095578.1 AK122781.1 AK225250.1 AK225258.1 AK292294.1 AK292614.1 BC004112.2 BC008040.2 BC009419.1 BC014439.1 BC030553.1 12 DOTS entries: DT.97787241 DT.121009204 DT.100818143 DT.100818135 DT.100036081 DT.100818141 DT.121009321 DT.95274954 DT.100722931 DT.100818142 DT.100698066 DT.91708490 24/113 AceView cDNA sequences (see all 113): BU626812 AI074186 AK022402 BC030553 BM916526 BM471470 CA307119 BM810136 CD369198 NM_182965 BX106465 CD366097 AA026251 BM709951 AI042283 BU630558 BC004112 BU728196 BQ027486 BE904632 BU736749 BU617770 CD676171 NM_021972
 highest scoring ESTs for SPHK1:AI769914 AA026479 AA081127 AA081152 AA232646 AA232791 AA372241 AA372249 AA639414 AF200328 Unigene Cluster for SPHK1: Sphingosine kinase 1 Hs.68061 [show with all ESTs]Unigene Representative Sequence: AK095578
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SPHK1 (see all 11)
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b |
|---|
|
| SP1: | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for SPHK1
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000323374(uc002jrf.1 uc002jrg.1 uc010wtc.1 uc002jrh.2 uc002jrj.2 uc002jri.2)
ENST00000392496(uc002jrk.3)
|
Expression
for SPHK1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| SPHK1 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching SPHK1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 51923_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
AI769914 |
1.00 |
1.00 |
1.00 |
1 |
| 219257_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_021972 |
0.60 |
1.00 |
0.82 |
1 |
| 219257_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
SPHK1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GAGAAGGGCA
SOURCE GeneReport for Unigene cluster: Hs.68061
UniProtKB/Swiss-Prot: SPHK1_HUMAN, Q9NYA1Tissue specificity: Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle
SABiosciences Expression via Pathway-Focused PCR Arrays including SPHK1 (see all 5): PAHS-015A PAHS-024A
|
Orthologs
for SPHK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SPHK1 gene from 5/9 species (see all 9)
About this table Species with no ortholog for SPHK1
ENSEMBL Gene Tree for SPHK1 (if available) |
Paralogs
for SPHK1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for SPHK1 gene
- AGK2 SPHK22
SPHK1 for paralogs About GeneDecksing
|
Genomic Variants
for SPHK1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 17 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for SPHK1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SPHK1
2 CNVs: 73036 5032 | | QIAGEN SeqTarget long-range PCR primers for resequencing SPHK1 |
|
Disorders & Mutations
for SPHK1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPHK1 for disorders About GeneDecksing
OMIM: 603730
10/17 Novoseek disease relationships for SPHK1 gene (see all 17)
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glioblastoma |
44.4 |
15 |
19074142 (5), 16106218 (3), 19723667 (2), 17855624 (1) (see all 5) |
| glioblastoma multiforme |
35.6 |
4 |
16106218 (2), 19074142 (1), 19723667 (1) |
| renal fibrosis |
27 |
2 |
19789541 (1), 19657322 (1) |
| cancer |
25.9 |
40 |
18691013 (4), 18638570 (3), 18701480 (3), 18620522 (3) (see all 14) |
| tumors |
22.4 |
32 |
18058224 (5), 20508814 (2), 17699730 (1), 18638570 (1) (see all 11) |
| inflammation |
18.8 |
6 |
17913601 (1), 15191888 (1), 15743396 (1), 19665772 (1) (see all 5) |
| necrosis |
17.8 |
6 |
17699730 (1), 15710602 (1), 20053797 (1), 16269668 (1) (see all 5) |
| breast cancer |
17.6 |
15 |
16194537 (4), 12881510 (2), 18701480 (1), 20110355 (1) (see all 9) |
| glioma |
9.67 |
9 |
19147534 (2), 18055454 (2), 17855624 (2), 17376432 (1) |
| colon cancer |
8.18 |
14 |
18824518 (3), 19240026 (3), 18701480 (1) |
About this table
Human Genome Epidemiology (HuGE) Navigator: SPHK1 (1 document)
Export disorders and mutations for SPHK1 gene to outside databases
|
Medical News
for SPHK1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for SPHK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/237 PubMed articles for SPHK1 gene, integrated from 7 sources (see all 237):
(articles sorted by number of sources associating them with SPHK1)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity. (PubMed id 12080051)1, 2 Lacana E.... Spiegel S. (2002)
- Functional characterization of human sphingosine kinase-1. (PubMed id 10802064)1, 2 Nava V.E.... Spiegel S. (2000)
- Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes. (PubMed id 10947957)1, 2 Pitson S.M.... Wattenberg B.W. (2000)
- Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution. (PubMed id 10863092)1, 2 Melendez A.J.... Takacs L. (2000)
- Molecular cloning and functional characterization of murine sphingosine kinase. (PubMed id 9726979)1, 3 Kohama T....Spiegel S. (1998)
- Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival. (PubMed id 18980995)1, 7 Li J....Li M. (2008)
- Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells. (PubMed id 17482291)1, 7 Francy J.M....Yun J.K. (2007)
- Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition. (PubMed id 19782042)1, 7 Hengst J.A....Yun J.K. (2009)
- Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells. (PubMed id 19074142)1, 7 Paugh B.S....Kordula T. (2009)
|
External Searches for SPHK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SPHK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPHK1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPHK1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SPHK1 gene:
Search GeneIP for patents involving SPHK1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPHK1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
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 |
| | |
 |  |  |  | |
 | Antibodies & Assays for SPHK1 |
| | | | Tocris compounds for SPHK1 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for SPHK1 |
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