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ST13 Gene

protein-coding   GIFtS: 62

GC22M041220
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
(Previous name: suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for ST13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)1 2     AAG22
SNC61 2 3     FLJ272602
HIP1 2 3     HSPABP2
FAM10A11 2 3     PRO07862
P481 2 5     Hsp70-interacting protein2
HSPABP11 2     hsc70-interacting protein2
Renal carcinoma antigen NY-REN-332 3     heat shock 70kD protein binding protein2
Putative tumor suppressor ST132 3     MGC1299522
Progesterone receptor-associated p48 protein2 3     FAM10A42
Suppression of tumorigenicity 13 protein2 3     aging-associated protein 22
HOP2 5     Hip3
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein)1     Protein FAM10A13

External Ids:    HGNC: 113431   Entrez Gene: 67672   Ensembl: ENSG000001003807   UniProtKB: P505023   

Export aliases for ST13 gene to outside databases

Previous GC identifers: GC22M037835 GC22M039463 GC22M039545


Summaries
for ST13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ST13:
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70
and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which
requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated
in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene. (provided by RefSeq)

UniProtKB/Swiss-Prot: F10A1_HUMAN, P50502
Function: One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the
HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its
own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity)

Gene Wiki entry for ST13

Genomic Views
for ST13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ST13 gene promoter:
         HSF1 (long)   C/EBPalpha   AhR   PPAR-gamma2   PPAR-gamma1   SREBP-1a   SREBP-1b   SREBP-1c   FAC1   c-Myb   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ST13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

ST13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ST13 gene location

GeneLoc gene densities for chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M041220:  view genomic region     (about GC identifiers)

Start:
 41,220,539 bp from pter
End:
 41,253,026 bp from pter
Size:
 32,488 bases
Orientation:
 minus strand

1 alternative location:
Chr22- 24,182,632-24,214,721     
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  

Proteins
for ST13 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: F10A1_HUMAN, P50502 (See protein sequence)
Recommended Name: Hsc70-interacting protein  
Size: 369 amino acids; 41332 Da
Subunit: Homotetramer. Interacts with HSC70 as well as DNAJ homologs and HSP90 (By similarity)
Subcellular location: Cytoplasm (By similarity)
PDB structures from and Proteopedia :
1UZS (3D)    
Secondary accessions: O14999

Explore the universe of human proteins at neXtProt for ST13: NX_P50502 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_003923.2  

    ENSEMBL proteins: 
    ENSP00000412049 ENSP00000397062 ENSP00000392067 ENSP00000216218 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Sigma-Aldrich Proteins for ST13
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for ST13
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for ST13 
    Novus Biologicals Proteins for ST13
    Novus Biologicals Lysate for ST13
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for ST13

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IEA--
    About this table

    ST13 for ontologies           About GeneDecksing



    Antibodies for ST13: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ST13
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for ST13  (HIP)
    OriGene Antibodies (see all 2): ST13
    GenScript Custom Superior Antibodies Services for ST13 
    Novus Biologicals Antibodies for ST13
    Epitomics antibodies for ST13

    Assays for ST13: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ST13 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ST13 

    Protein Domains/
    Families
    for ST13 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ST13 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR006636 STI1_HS-bd
     IPR001440 TPR-1
     IPR011990 TPR-like_helical
     IPR013026 TPR-contain
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry P50502

    ProtoNet protein and cluster: P50502

    1 Blocks protein family: IPB006636 Heat shock chaperonin-binding

    UniProtKB/Swiss-Prot: F10A1_HUMAN, P50502
    Similarity: Belongs to the FAM10 family
    Similarity: Contains 1 STI1 domain
    Similarity: Contains 3 TPR repeats


    Gene Function
    for ST13 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: F10A1_HUMAN, P50502
    Function: One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the
    HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its
    own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity)

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA for ST13
    Sigma-Aldrich shRNA Panels and shRNA for ST13
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): ST13
    OriGene shRNA RFP (see all 4): ST13
    OriGene basic RS shRNA (see all 4): ST13
    OriGene siRNA: ST13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ST13 
    miRNA:Sigma-Aldrich microRNA Mimics for ST13
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ST13 
    5 SABiosciences Assays for microRNAs that regulate ST13:
    hsa-miR-103 hsa-miR-509-5p hsa-miR-561 hsa-miR-509-3-5p hsa-miR-493

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: ST13
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ST13
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ST13
    OriGene 3'-UTR clone: ST13 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ST13 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for ST13 

    Genatlas biochemistry entry for ST13:
    suppression of tumorigenicity 13,colon carcinoma,see TSG22C

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488 binding ----
    GO:0030674 protein binding, bridging TAS8721986
    About this table

    ST13 for ontologies           About GeneDecksing


    Pathways & Interactions
    for ST13 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for ST13 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ST13

    5 Interacting proteins for ST13 (P505022) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BAG1Q999332MINT-45857 MINT-45858
    CD101Q930332MINT-65086
    MAP3K3Q997592MINT-48449
    OLFM2O958972MINT-63324
    SMAD2Q157962MINT-61598
    About this table

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457 protein folding TAS8721986
    About this table

    ST13 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ST13 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    ST13 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ST13
    5 Novoseek chemical compound relationships for ST13 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    steroid 52.7 14 10702249 (2), 17323428 (1), 8939864 (1), 12093808 (1) (see all 8)
    progesterone 46.1 8 8721986 (3), 10630990 (1), 10364185 (1), 14627198 (1) (see all 5)
    prostacyclin 43.5 6 17164137 (2), 20395296 (1), 11961139 (1), 17704830 (1) (see all 5)
    atp 40.1 9 10364185 (1), 11809754 (1), 12093808 (1), 12563018 (1) (see all 6)
    adp 5.42 2 9321400 (1), 7585962 (1)
    About this table



    Transcripts
    for ST13 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA for ST13
    Sigma-Aldrich shRNA Panels and shRNA for ST13
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): ST13
    OriGene shRNA RFP (see all 4): ST13
    OriGene basic RS shRNA (see all 4): ST13
    OriGene siRNA: ST13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ST13 
    miRNA: Sigma-Aldrich microRNA Mimics for ST13
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ST13 
    5 SABiosciences Assays for microRNAs that regulate ST13:
    hsa-miR-103 hsa-miR-509-5p hsa-miR-561 hsa-miR-509-3-5p hsa-miR-493
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: ST13
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ST13
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ST13
    OriGene 3'-UTR Clone: ST13 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ST13 
    Primers: OriGene genome-wide validated SYBR primer pairs: ST13
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ST13: PPH01184A

    REFSEQ mRNAs for ST13 gene: 

    NM_003932.3  

    Additional cDNA sequence: 

    AF116650.1 AK130770.1 AK303530.1 AK312399.1 AK316155.1 AY513286.1 AY826824.1 AY826825.1 
    BC015317.1 BC052982.1 BC071629.1 BC101206.1 BC101207.2 BC101208.1 BC107148.1 BC121107.1 
    BC121108.1 BC139724.1 CR456586.1 CR592284.1 CR592764.1 CR593758.1 CR594833.1 CR596395.1 
    CR606507.1 CR607174.1 CR607448.1 CR607785.1 CR608217.1 CR610981.1 CR612386.1 CR615156.1 
    CR617206.1 CR617748.1 CR623583.1 CR625864.1 U17714.1 U28918.1 

    24/62 DOTS entries (see all 62):

    DT.99998054  DT.100000399  DT.100892017  DT.456282  DT.100892027  DT.120649873  DT.100892010  DT.120649960 
    DT.120649995  DT.85101734  DT.92464568  DT.92464561  DT.120649901  DT.95149390  DT.121116356  DT.120650009 
    DT.100892054  DT.92343743  DT.100892033  DT.92464548  DT.95149407  DT.95076778  DT.100034556  DT.100653922 

    24/818 AceView cDNA sequences (see all 818):

    CN483302 CA443830 BQ961449 BQ775864 BE708363 BM787552 CR623583 CR612386 
    BQ421925 BM830523 AA757844 BI859595 CR617748 BG575836 AA977447 BQ222732 
    AI888182 AA758434 AK130770 BM806781 AI564242 AA357384 AA418609 CA391000 

    highest scoring ESTs for ST13:

    U17714 AK130770 AL048431 AU117682 AU131250 AU131525 AU133205 AU133395 AU137032 AW444807 

    Unigene Cluster for ST13:

    Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
    Hs.712713  [show with all ESTs]
    Unigene Representative Sequence: NM_003932


    GeneLoc Exon Structure

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000413424 ENST00000455824 ENST00000411695 ENST00000216218(uc003aze.2 uc011aow.1)
    ENST00000480048 ENST00000495652

    Expression
    for ST13 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    ST13 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching ST13 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    1640_at2, 3 U95-A 1 0.88 1.00 1.00 1.00 U17714 1.00 1.00 1.00 1
    207040_s_at2, 3 U133-A 7 1.00 0.62 -- -- NM_003932 0.60 1.00 0.82 1
    208666_s_at2, 3 U133-A 1 0.82 1.00 -- -- BE866412 0.60 1.00 0.82 1
    208667_s_at2, 3 U133-A 1 0.82 1.00 -- -- U17714 1.00 1.00 1.00 1
    207040_s_at2 U133Plus2 7 1.00 0.62 -- -- -- -- -- -- --
    208666_s_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    208667_s_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    About this table

    ST13 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    ST13 gene expression
    ST13 gene electronic northern expression
    ST13 gene sage expression
    About these images

    CGAP SAGE TAG: CAGGATCCAG

    SOURCE GeneReport for Unigene cluster: Hs.712713

    Expression variation in blood from EXPOLDB for ST13

    Primers: OriGene genome-wide validated SYBR primer pairs: ST13
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ST13: PPH01184A
        SABiosciences Custom PCR Arrays for ST13 


    Orthologs
    for ST13 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ST13 gene from 5/16 species (see all 16)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 LOC6079601   -- similar to heat shock 70kD protein binding protein 93.59(n)
    95.39(a)    		 607960  XM_844401.1  XP_849494.1 
    chimpanzee
    (Pan troglodytes)    		 ST131   -- suppression of tumorigenicity 13 (colon carcinoma) more 100(n)
    100(a)    		 745054  XM_001167706.1  XP_001167706.1 
    cow
    (Bos taurus)    		 ST131   -- suppression of tumorigenicity 13 (colon carcinoma) more 93.96(n)
    97.56(a)    		 510494  XM_881783.2  XP_886876.2 
    rat
    (Rattus norvegicus)    		 St131   -- suppression of tumorigenicity 13 89.67(n)
    92.39(a)    		 81800  NM_031122.1  NP_112384.1 
    mouse
    (Mus musculus)    		 St131 , 5 15 (38.07 cM)5
    		 suppression of tumorigenicity 131, 5 90.49(n)1
    94.57(a)1    		 703561  NM_133726.21  NP_598487.11 
     AK0035455  AK0139815  (see all 24)
    About this table        Species with no ortholog for ST13

    ENSEMBL Gene Tree for ST13 (if available)

    Paralogs
    for ST13 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for ST13 gene
    ST13P52  

    ST13 for paralogs           About GeneDecksing


    Pseudogenes
    14 related pseudogenes



    Genomic Variants
    for ST13 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/282 NCBI SNPs in ST13 are shown (see all 282)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 22 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs806851,2
    		C,41232343(+) ccagcT/Cacttg 1 -- int18Minor allele frequency- C:0.00EA NA WA 58
    rs1383351,2
    		C,F,O,A,H,41227086(+) TTGTAG/CAAAAA 1 -- int118Minor allele frequency- C:0.37EA NA NS WA 932
    rs1383361,2
    		C41229585(+) AAAAA-/AGAAAT 1 -- int1 trp31Minor allele frequency- A:0.00NA 2
    rs1383371,2
    		C,F,A,H,41231053(+) GTTAAA/GTTCAC 1 -- int119Minor allele frequency- G:0.28NS EA NA WA 1234
    rs1383411,2
    		--41239905(+) TTTTT-/TAAATA 1 -- int1 trp30--------
    rs1383421,2
    		C,F,A,H,41241945(+) ACAGGC/TATATC 1 -- int110Minor allele frequency- T:0.32NS EA NA WA 500
    rs1383431,2
    		C41243298(+) TTTGGG/-AGGCC 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1383441,2
    		C,F,O,A,H,41244398(+) CAGTAC/GTATCA 1 -- int116Minor allele frequency- G:0.30NS EA NA WA 1046
    rs1383451,2
    		C41245929(+) AAAAAA/-GCCTT 1 -- int1 trp31Minor allele frequency- -:0.00NA 2
    rs1383461,2
    		C,A41247938(+) gagacG/Agggtt 1 -- int16Minor allele frequency- A:0.15MN NA WA 194
    About this table

    HapMap Linkage Disequilibrium images for ST13 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ST13
         1 CNV: 91067

    QIAGEN SeqTarget long-range PCR primers for resequencing ST13 

    Disorders & Mutations
    for ST13 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ST13 for disorders           About GeneDecksing

    OMIM: 606796

    2 Novoseek disease relationships for ST13 gene

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 52.9 14 10330192 (1), 17323428 (1), 18052042 (1), 10567384 (1) (see all 10)
    tumors 3.42 1 9925927 (1)
    About this table


    Export disorders and mutations for ST13 gene to outside databases

    Medical News
    for ST13 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for ST13 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/93 PubMed articles for ST13 gene, integrated from 7 sources (see all 93):
    (articles sorted by number of sources associating them with ST13)
    1. Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein. (PubMed id 8721986)1, 2, 3, 7 Prapapanich V.... Smith D.F. (1996)
    2. Assignment1 of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24-->q25 by in situ hybridization. (PubMed id 9925927)1, 3, 7 Zhang Y....Zheng S. (1998)
    3. Phosphoproteomic analysis of the human pituitary. (PubMed id 16807684)1, 2 Beranova-Giorgianni S.... Giorgianni F. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2 Scanlan M.J....Old L.J. (1999)
    8. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    9. Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. (PubMed id 9292708)1, 2 Cao J.... Zheng S. (1997)
    10. Differential expression of HSU17714 gene in colorectal cancer and normal colonic mucosa. (PubMed id 9387309)1, 2 Mo Y.... Shen D. (1996)

    External Searches for ST13 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ST13 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6767 HGNC: 11343 AceView: ST13 Ensembl:ENSG00000100380 euGenes: HUgn6767
    ECgene: ST13 H-InvDB: ST13

    Other Databases showing ST13 gene

    (According to HUGE)
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    Specialized Databases showing ST13 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for ST13 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
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    Search GeneIP for patents involving ST13

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