Aliases &
Descriptions
for SYNGR4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| synaptogyrin 41 2 | | MGC1258052 | | synaptogyrin-42 |
Export aliases for SYNGR4 gene to outside databasesPrevious GC identifers: GC19P049513 GC19P049235 GC19P053543 GC19P053559 GC19P048867 |
Summaries
for SYNGR4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SYNGR4:
This gene encodes an integral membrane protein. The gene belongs to the synaptogyrin gene family. Like other members ofthe family the protein contains four transmembrane regions. The exact function of this protein is unclear. (providedby RefSeq)
|
Genomic Views
for SYNGR4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SYNGR4 gene promoter:
C/EBPalpha CHOP-10 CUTL1 XBP-1 Pbx1a E2F-1 E2F E2F-3a E2F-4 E2F-5
Other transcription factors
Search SABiosciences Chromatin IP Primers for SYNGR4
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for SYNGR4  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.3SYNGR4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P045248: view genomic region
(about GC identifiers)
Start:
|
45,248,362 bp from pter |
End:
|
45,260,340 bp from pter |
Size:
|
11,979 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr19+ 48,867,657-48,879,627 |
RefSeq DNA sequence:- NC_000019.9 NT_011109.16
|
Proteins
for SYNGR4 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: SNG4_HUMAN, O95473 (See
protein sequence)Recommended Name: Synaptogyrin-4 Size: 234 amino acids; 25820 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q3KP58Explore the universe of human proteins at neXtProt for SYNGR4: NX_O95473
REFSEQ proteins: NP_036583.2
ENSEMBL proteins: ENSP00000344041
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
SYNGR4 for ontologies About GeneDecksing
Antibodies for SYNGR4:
Assays for SYNGR4: |
Protein
Domains/
Families
for SYNGR4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SYNGR4 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95473ProtoNet protein and cluster: O95473 1 Blocks protein family: IPB008253 Marvel
UniProtKB/Swiss-Prot: SNG4_HUMAN, O95473Similarity: Belongs to the synaptogyrin familySimilarity: Contains 1 MARVEL domain |
Gene Function
for SYNGR4 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for SYNGR4 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for SYNGR4
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYNGR4
|
Drugs & Compounds
for SYNGR4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for SYNGR4
|
Transcripts
for SYNGR4 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for SYNGR4 gene: NM_012451.3 Additional cDNA sequence: AJ011733.1 BC106891.2 1 DOTS entry: DT.206820 23 AceView cDNA sequences: AI081072 AI222412 AA953389 NM_012451 BM797584 BV176232 BF508220 BM792897 AJ011733 BM854750 AI582272 AI032366 AI214645 AA835071 AA719355 BG219279 AA551879 AI214923 BG720827 AA442228 AA442893 AA971366 AW662802
 highest scoring ESTs for SYNGR4:AJ011733 AA442893 AA551879 AA719355 AA835071 AA953389 AI081072 AI214645 AI214923 AI222412 Unigene Cluster for SYNGR4: Synaptogyrin 4 Hs.408333 [show with all ESTs]Unigene Representative Sequence: NM_012451
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for SYNGR4
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | - | | | | | |
About this scheme
ECgene alternative splicing isoforms for SYNGR4
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000344846(uc002piz.2)
|
Expression
for SYNGR4 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| SYNGR4 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching SYNGR4 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 34495_r_at2, 3
|
U95-A |
1 |
0.69 |
1.00 |
1.00 |
1.00 |
AJ011733 |
1.00 |
1.00 |
1.00 |
1 |
| 206719_at2, 3
|
U133-A |
1 |
0.73 |
1.00 |
-- |
-- |
NM_012451 |
0.60 |
1.00 |
0.82 |
1 |
| 206719_at2
|
U133Plus2 |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
SYNGR4 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.408333
Expression variation in blood from EXPOLDB for SYNGR4 SABiosciences Custom PCR Arrays for SYNGR4
|
Orthologs
for SYNGR4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SYNGR4 gene from 5 species
About this table Species with no ortholog for SYNGR4
ENSEMBL Gene Tree for SYNGR4 (if available) |
Paralogs
for SYNGR4 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for SYNGR4 gene
- SYNGR2P12 SYNGR12 SYNGR32 SYNGR22
SYNGR4 for paralogs About GeneDecksing
|
Genomic Variants
for SYNGR4 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SYNGR4
3 CNVs: 47965 5106 32261 | | QIAGEN SeqTarget long-range PCR primers for resequencing SYNGR4 |
|
Disorders & Mutations
for SYNGR4 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SYNGR4 for disorders About GeneDecksing
OMIM: 608373
Export disorders and mutations for SYNGR4 gene to outside databases
|
Medical News
for SYNGR4 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for SYNGR4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for SYNGR4 gene integrated from 7 sources:
(articles sorted by number of sources associating them with SYNGR4)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- A transcript map of the chromosome 19q-Arm glioma tumor suppressor region. (PubMed id 10708517)1 Smith J.S.... Jenkins R.B. (2000)
- Characterization of the human synaptogyrin gene family. (PubMed id 9760194)1 Kedra D....Dumanski J.P. (1998)
|
External Searches for SYNGR4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SYNGR4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SYNGR4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SYNGR4 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SYNGR4 gene:
Search GeneIP for patents involving SYNGR4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SYNGR4 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
 |
 |
| | |
 |  |  |  | |
| |  | Search Tocris compounds for SYNGR4 |
| |  |  |  |  | | | | |
 | | |
|
|
