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TMED2 Gene

protein-coding   GIFtS: 52

GC12P121030
transmembrane emp24 domain trafficking protein 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
transmembrane emp24 domain trafficking protein 21 2     FLJ213232
RNP241 2 3     coated vesicle membrane protein2
P24A1 2     transmembrane emp24 domain-containing protein 22
Membrane protein p24A2 3     

External Ids:    HGNC: 169961   Entrez Gene: 109592   Ensembl: ENSG000000865987   UniProtKB: Q153633   

Export aliases for TMED2 gene to outside databases

Previous GC identifers: GC12P122595 GC12P124069


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TMED2_HUMAN, Q15363
Function: Could have a role in the budding of coatomer-coated and other species of coated vesicles. Could bind cargo
molecules to collect them into budding vesicles

Gene Wiki entry for TMED2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMED2 gene promoter:
         NRSF form 2   NRSF form 1   CUTL1   SRY   Pax-5   deltaCREB   CREB   STAT3   C/EBPalpha   Egr-3   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for TMED2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TMED2 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

TMED2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMED2 gene location

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P121030:  view genomic region     (about GC identifiers)

Start:
121,030,441 bp from pter
End:
121,044,052 bp from pter
Size:
13,612 bases
Orientation:
plus strand

1 alternative location:
Chr12+ 124,069,076-124,082,681     
RefSeq DNA sequence:
NC_000012.11  NT_009755.19  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: TMED2_HUMAN, Q15363 (See protein sequence)
Recommended Name: Transmembrane emp24 domain-containing protein 2 precursor  
Size: 201 amino acids; 22761 Da
Subunit: Interacts with ARFGAP1, inhibiting the GTPase-activating activity of ARFGAP1 (By similarity). Found in a
complex composed at least of SURF4, TMED2 and TMED10
Subcellular location: Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle,
COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I
membrane protein. Note=Golgi-derived coatomer-coated vesicles

Explore the universe of human proteins at neXtProt for TMED2: NX_Q15363 

REFSEQ proteins: NP_006806.1  

ENSEMBL proteins: 
ENSP00000262225 ENSP00000405845 ENSP00000388691 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate: TMED2
GenScript Custom Purified and Recombinant Proteins Services for TMED2 
Novus Biologicals Protein for TMED2
Novus Biologicals Lysate for TMED2
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

5/11 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 11):

GO IDQualified GO termEvidencePubMed IDs
GO:0000139 Golgi membrane IEA--
GO:0005792 microsome ISS--
GO:0005793 ER-Golgi intermediate compartment IDA15308636
GO:0005794 Golgi apparatus IEA--
GO:0016020 membrane IEA--
About this table

TMED2 for ontologies           About GeneDecksing



Antibodies for TMED2: 
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Sigma-Aldrich Antibodies for TMED2
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Epitomics antibodies for TMED2

Assays for TMED2: 
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Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for TMED2 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for TMED2 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMED2 for domains           About GeneDecksing

2 InterPro domains/families:
 IPR009038 GOLD
 IPR000348 Emp24/Gp25L/p24

Graphical View of Domain Structure for InterPro Entry Q15363

ProtoNet protein and cluster: Q15363

1 Blocks protein family: IPB000348 emp24/gp25L/p24 family

UniProtKB/Swiss-Prot: TMED2_HUMAN, Q15363
Similarity: Belongs to the EMP24/GP25L family
Similarity: Contains 1 GOLD domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: TMED2_HUMAN, Q15363
Function: Could have a role in the budding of coatomer-coated and other species of coated vesicles. Could bind cargo
molecules to collect them into budding vesicles

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for TMED2
Sigma-Aldrich shRNA for TMED2
OriGene 29mer shRNA kits in GFP-retroviral vector: TMED2
OriGene shRNA RFP: TMED2
OriGene basic RS shRNA: TMED2
OriGene siRNA: TMED2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMED2 
miRNA:Sigma-Aldrich microRNA Mimics for TMED2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMED2 
4 SABiosciences Assays for microRNAs that regulate TMED2:
hsa-miR-649 hsa-miR-527 hsa-miR-518a-5p hsa-miR-573

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: TMED2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TMED2
OriGene untagged cDNA clones in CMV expression vector: TMED2
OriGene 3'-UTR clone: TMED2 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for TMED2 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for TMED2 

1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005515 protein binding IPI16641999
About this table

TMED2 for ontologies           About GeneDecksing

Animal Models: 6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tmed2):

cardiovascular systemembryogenesisgrowth/sizelethality-prenatal/perinatallimbs/digits/tail
nervous system

TMED2 for phenotypes           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for TMED2 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMED2

2 Interacting proteins for TMED2 (Q153631 ENSP000002622253) via UniProtKB, MINT, and/or STRING
InteractantInteraction Details
GeneCardExternal ID(s)
TMED10P497551, ENSP000003031453EBI-998485,EBI-998422 STRING: ENSP00000303145
--ENSP000003495193STRING: ENSP00000349519
About this table

3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006810 transport ----
GO:0015031 protein transport IEA--
GO:0016192 vesicle-mediated transport IEA--
About this table

TMED2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMED2


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for TMED2
Sigma-Aldrich shRNA for TMED2
OriGene 29mer shRNA kits in GFP-retroviral vector: TMED2
OriGene shRNA RFP: TMED2
OriGene basic RS shRNA: TMED2
OriGene siRNA: TMED2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMED2 
miRNA: Sigma-Aldrich microRNA Mimics for TMED2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMED2 
4 SABiosciences Assays for microRNAs that regulate TMED2:
hsa-miR-649 hsa-miR-527 hsa-miR-518a-5p hsa-miR-573
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: TMED2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TMED2
OriGene untagged cDNA clones in CMV expression vector: TMED2
OriGene 3'-UTR Clone: TMED2 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for TMED2 
Primers: OriGene genome-wide validated SYBR primer pairs: TMED2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for TMED2: PPH10004A

REFSEQ mRNAs for TMED2 gene: 

NM_006815.3  

Additional cDNA sequence: 

AK024976.1 AK298167.1 AK303189.1 AK312975.1 BC025957.1 CR541663.1 CR541682.1 CR620150.1 
X92098.1 

24/31 DOTS entries (see all 31):

DT.100679824  DT.75193702  DT.91979006  DT.100676134  DT.100679813  DT.100679819  DT.100758886  DT.100679818 
DT.100679821  DT.100679822  DT.97855376  DT.100679814  DT.95263835  DT.95263842  DT.97855375  DT.100679815 
DT.121107135  DT.95263820  DT.100679820  DT.100031694  DT.100679825  DT.100861921  DT.121107125  DT.121107126 

24/821 AceView cDNA sequences (see all 821):

BG778100 CR612554 AA773432 BF724130 AV658574 AA971825 F10166 CA941694 
CA445272 CA950234 AA298291 AA999791 AA305298 AA233919 AI471088 AA587489 
Z38930 CB146186 AI698520 AI758393 C02110 AU116907 AA447084 AI285454 

highest scoring ESTs for TMED2:

AI985603 X92098 AA001157 AA001197 AA028932 AA031517 AA031518 AA081949 AA101171 AA121047 

Unigene Cluster for TMED2:

Transmembrane emp24 domain trafficking protein 2
Hs.75914  [show with all ESTs]
Unigene Representative Sequence: NM_006815


GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for TMED2

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1:                                          
SP2:                                          
SP3:                                          

About this scheme

ECgene alternative splicing isoforms for TMED2
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000262225(uc001ufg.2) ENST00000438031 ENST00000432022

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

TMED2 expression in normal and diseased human tissues

1  / 2  / 3

8 probe-sets matching TMED2 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
36972_at2, 3 U95-A 1 1.00 1.00 0.99 0.87 X92098 1.00 1.00 1.00 1
75058_f_at2, 3 U95-D 1 1.00 1.00 0.99 1.13 AI985603 1.00 1.00 1.00 1
200087_s_at2, 3 U133-B 1 1.00 1.00 -- -- AK024976 0.80 1.00 0.91 1
204427_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_006815 0.60 1.00 0.82 1
204426_at2, 3 U133-A 2 1.00 0.91 -- -- NM_006815 0.60 1.00 0.82 1
200087_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
204427_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
204426_at2 U133Plus2 2 1.00 0.91 -- -- -- -- -- -- --
About this table

TMED2 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
TMED2 gene expression
TMED2 gene electronic northern expression
TMED2 gene sage expression
About these images

CGAP SAGE TAG: CCAAGTTTTT

SOURCE GeneReport for Unigene cluster: Hs.75914
Primers: OriGene genome-wide validated SYBR primer pairs: TMED2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for TMED2: PPH10004A
    SABiosciences Custom PCR Arrays for TMED2 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TMED2 gene from 5/18 species (see all 18)
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
TMED21   -- transmembrane emp24 domain trafficking protein 2 99.17(n)
100(a)
745933  XM_001152449.1  XP_001152449.1 
cow
(Bos taurus)
TMED21   -- transmembrane emp24 domain trafficking protein 2 91.04(n)
93.03(a)
785350  XM_001250509.1  XP_001250510.1 
rat
(Rattus norvegicus)
Tmed21   -- transmembrane emp24 domain trafficking protein 2 92.21(n)
99.5(a)
65165  NM_031722.2  NP_113910.1 
mouse
(Mus musculus)
Tmed25
ENSMUSG000000744601
5 (63.65 cM)5
transmembrane emp24 domain trafficking protein 25
predicted gene, ENSMUSG000000744601
91.54(n)1
99(a)1
1000423431  XM_001478013.11  XP_001478063.11 
 AA4070575  AB0252185  (see all 23)
chicken
(Gallus gallus)
TMED21   -- transmembrane emp24 domain trafficking protein 2 85.9(n)
93.03(a)
416821  NM_001006186.1  NP_001006186.1 
About this table        Species with no ortholog for TMED2

ENSEMBL Gene Tree for TMED2 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Pseudogenes
1 related pseudogene



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/155 NCBI SNPs in TMED2 are shown (see all 155)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 12 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs65511,2
C,F,A,H,124082240(-) AGAAAA/G/TACCCA 1 -- ut31 ese3 trp313NS EA NA WA 630
rs144421,2
--124082012(-) GGAAAG/AAAAAA 1 -- ut311Minor allele frequency- A:0.00MN 184
rs7864211,2
C,H,124082863(-) ACCTAT/CGCAGA 1 -- ng3114Minor allele frequency- C:0.00EA NA MN WA 402
rs7864451,2
C,A124068361(+) accagC/Actgac 1 -- ng515Minor allele frequency- A:0.02EA NS NA 184
rs7864461,2
C,H,124069213(+) GTGCTA/C/G/
        
CTGGC
4 L syn1 ref110EA NA MN WA 260
rs7864471,2
C,F,A,H,124069667(+) GAATCG/AGGCGC 1 -- int119Minor allele frequency- A:0.38EA NA NS WA 798
rs7864481,2
C,F,A,H,124070214(-) GTCTCC/TCCCTT 1 -- int1 trp313Minor allele frequency- T:0.17EA NS NA WA 2020
rs7864491,2
C,F,A,H,124071728(+) tcgctT/Ctttcg 1 -- int113Minor allele frequency- C:0.28NA EA NS 676
rs7864501,2
C,A,H,124071765(+) cttggA/Cttact 1 -- int17Minor allele frequency- C:0.07NA WA 14
rs7864511,2
C,A,H124075511(+) ggcaaC/Tggagc 1 -- int16Minor allele frequency- T:0.08NA WA 12
About this table

HapMap Linkage Disequilibrium images for TMED2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TMED2
     1 CNV: 5313

QIAGEN SeqTarget long-range PCR primers for resequencing TMED2 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/15 PubMed articles for TMED2 gene, integrated from 7 sources (see all 15):
(articles sorted by number of sources associating them with TMED2)
  1. Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. (PubMed id 8663407)1, 2, 3, 7 Blum R....Schulz I. (1996)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. The cargo receptor p24A facilitates calcium sensing r eceptor maturation and stabilization in the early secretory pathway. (PubMed id 20361938)1 Stepanchick A. and Breitwieser G.E. (2010)
  4. The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi. (PubMed id 18287528)2 Mitrovic S.... Hauri H.-P. (2008)
  5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
  6. p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking. (PubMed id 17693410)1 Luo W....Reiser G. (2007)
  7. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. (PubMed id 16641999)1 Chen F....Fraser P. (2006)
  8. Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46. (PubMed id 15308636)1 Breuza L....Hauri H.P. (2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  10. Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus. (PubMed id 11739402)1 Barr F.A.... Koerner R. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 10959 HGNC: 16996 AceView: RNP24 Ensembl:ENSG00000086598 euGenes: HUgn10959
ECgene: TMED2 H-InvDB: TMED2

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for TMED2 gene:
Search GeneIP for patents involving TMED2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 Predesigned and custom siRNAs for TMED2 Antibodies for TMED2
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 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
 Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 3' UTR Clones for miRNA Target Studies
 miRNA Expression Plasmids

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TMED2
 SeqTarget long-range PCR primers for resequencing TMED2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TMED2
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TMED2
 GenScript Custom Purified and Recombinant Proteins Services for TMED2 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TMED2
 GenScript Custom Assay Services for TMED2 GenScript Custom Superior Antibodies Services for TMED2
 GenScript Custom overexpressing Cell Line Services for TMED2 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
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 Regulatory tfbs in TMED2 promoter
 Search Chromatin IP Primers for TMED2
 RT2 qPCR Primer Assay for TMED2
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 Assays for microRNAs that regulate TMED2
 SABiosciences Custom PCR Arrays for TMED2
 Search Tocris compounds for TMED2
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 Proteins for TMED2
 Lysates for TMED2
 Antibodies for TMED2
 Browse ProSpec Recombinant Proteins

 ELISAs and CLIAs for TMED2
       

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