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TTC12 Gene

protein-coding   GIFtS: 47

GC11P109112
tetratricopeptide repeat domain 12
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
tetratricopeptide repeat domain 121 2     tetratricopeptide repeat protein 122
TPARM1 2 5     tetratricopeptide repeat protein 12 variant 12
FLJ205351 2     tetratricopeptide repeat protein 12 variant 22
FLJ138591 2     OTTHUMP000001835122
TPR repeat protein 122 3     

External Ids:    HGNC: 237001   Entrez Gene: 549702   Ensembl: ENSG000001492927   UniProtKB: Q9H8923   

Export aliases for TTC12 gene to outside databases

Previous GC identifers: GC11P112722 GC11P112690 GC11P113185


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TTC12 gene promoter:
         HOXA9B   Meis-1   RFX1   MIF-1   AREB6   Nkx3-1 v4   Nkx3-1   Nkx3-1 v1   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for TTC12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TTC12 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.2   Ensembl cytogenetic band:  11q23.2   HGNC cytogenetic band: 11q23.2

TTC12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC12 gene location

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P109112:  view genomic region     (about GC identifiers)

Start:
109,112,836 bp from pter
End:
109,164,715 bp from pter
Size:
51,880 bases
Orientation:
plus strand

1 alternative location:
Chr11+ 113,185,301-113,254,266     
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: TTC12_HUMAN, Q9H892 (See protein sequence)
Recommended Name: Tetratricopeptide repeat protein 12  
Size: 705 amino acids; 78738 Da
Sequence caution: Sequence=BAA91242.1; Type=Erroneous initiation;
Secondary accessions: Q8N5H9 Q9NWY3
Alternative splicing: 2 isoforms:  Q9H892-1   Q9H892-2   

Explore the universe of human proteins at neXtProt for TTC12: NX_Q9H892 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_060338.3  

    ENSEMBL proteins: 
    ENSP00000402004 ENSP00000395082 ENSP00000400039 ENSP00000413335 ENSP00000419652 ENSP00000315160 
    ENSP00000376743 ENSP00000423788 ENSP00000278593 ENSP00000429128 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for TTC12 
    Novus Biologicals Protein for TTC12
    Novus Biologicals Lysate for TTC12
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins


    Antibodies for TTC12: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for TTC12
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for TTC12 
    Novus Biologicals Antibodies for TTC12
    Browse antibodies at Epitomics

    Assays for TTC12: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TTC12 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TTC12 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TTC12 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011990 TPR-like_helical
     IPR011989 ARM-like
     IPR001440 TPR-1
     IPR016024 ARM-type_fold
     IPR013026 TPR-contain

    Graphical View of Domain Structure for InterPro Entry Q9H892

    ProtoNet protein and cluster: Q9H892

    UniProtKB/Swiss-Prot: TTC12_HUMAN, Q9H892
    Similarity: Contains 3 TPR repeats


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for TTC12
    Sigma-Aldrich shRNA for TTC12
    OriGene 29mer shRNA kits in GFP-retroviral vector: TTC12
    OriGene shRNA RFP: TTC12
    OriGene basic RS shRNA: TTC12
    OriGene siRNA: TTC12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TTC12 
    miRNA:Sigma-Aldrich microRNA Mimics for TTC12
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TTC12 
    Search SABiosciences for Assays for microRNAs that regulate TTC12

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TTC12
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TTC12
    OriGene untagged cDNA clones in CMV expression vector: TTC12
    OriGene 3'-UTR clone: TTC12 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for TTC12 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for TTC12 

    3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824 catalytic activity ----
    GO:0005488 binding IEA--
    GO:0005524 ATP binding ----
    About this table

    TTC12 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for TTC12 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TTC12

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152 metabolic process ----
    About this table

    TTC12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TTC12


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for TTC12
    Sigma-Aldrich shRNA for TTC12
    OriGene 29mer shRNA kits in GFP-retroviral vector: TTC12
    OriGene shRNA RFP: TTC12
    OriGene basic RS shRNA: TTC12
    OriGene siRNA: TTC12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TTC12 
    miRNA: Sigma-Aldrich microRNA Mimics for TTC12
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TTC12 
    Search SABiosciences for Assays for microRNAs that regulate TTC12
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TTC12
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TTC12
    OriGene untagged cDNA clones in CMV expression vector: TTC12
    OriGene 3'-UTR Clone: TTC12 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for TTC12 
    Primers: OriGene genome-wide validated SYBR primer pairs: TTC12
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TTC12: PPH16164A

    REFSEQ mRNAs for TTC12 gene: 

    NM_017868.3  

    Additional cDNA sequence: 

    AK000542.1 AK023921.1 AK027161.1 AK091887.1 AK125909.1 AK223117.1 AK292331.1 BC011546.1 
    BC019086.2 

    17 DOTS entries:

    DT.99961473  DT.100020560  DT.108310  DT.100020559  DT.120720437  DT.97779874  DT.91955198  DT.100030480 
    DT.92424750  DT.70102660  DT.95257432  DT.95269636  DT.65287571  DT.40307708  DT.97854427  DT.91820313 
    DT.91853573 

    24/111 AceView cDNA sequences (see all 111):

    BQ218129 AA399653 NM_017868 AK023921 CF132464 AK027161 AU124478 BM698700 
    BC011546 BC019086 BC032355 BM473638 BM992919 AK000542 CN478998 BU684868 
    AI586953 BE261724 AK125909 AW513387 BU680990 AK091887 CD628682 BF725316 

    highest scoring ESTs for TTC12:

    AI799864 AA132777 AK000542 AK023921 AK091887 AL572896 AW076105 BC011546 BC019086 BF980079 

    Unigene Cluster for TTC12:

    Tetratricopeptide repeat domain 12
    Hs.288772  [show with all ESTs]
    Unigene Representative Sequence: AK125909


    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TTC12 (see all 10)

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                                                                -                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                      -                                                                                                                     

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          

    About this scheme

    ECgene alternative splicing isoforms for TTC12
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480233 ENST00000455306 ENST00000464224(uc001pnx.2) ENST00000436332
    ENST00000442859 ENST00000429951 ENST00000489064 ENST00000496311 ENST00000483239
    ENST00000314756 ENST00000478125 ENST00000393020 ENST00000494714(uc001pnw.2)
    ENST00000462711 ENST00000504025(uc001pnu.2 uc001pnv.2) ENST00000278593
    ENST00000520742

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    TTC12 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching TTC12 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    43087_at2, 3 U95-B 1 1.00 1.00 0.77 1.02 AI799864 1.00 1.00 1.00 1
    74046_at2, 3 U95-E 1 0.44 1.00 0.53 1.01 AI971251 0.20 1.00 0.72 1
    219587_at2, 3 U133-A 1 0.91 1.00 -- -- NM_017868 0.60 1.00 0.82 1
    215598_at*2, 3 U133-A 1 0.27 1.00 -- -- AK027161 0.40 1.00 0.76 1
    219587_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
    1554531_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
    215598_at*2 U133Plus2 1 0.27 1.00 -- -- -- -- -- -- --
    About this table

    TTC12 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    TTC12 gene expression
    TTC12 gene electronic northern expression
    TTC12 gene sage expression
    About these images

    CGAP SAGE TAG: GCCTAGAAAT

    SOURCE GeneReport for Unigene cluster: Hs.288772
    Primers: OriGene genome-wide validated SYBR primer pairs: TTC12
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TTC12: PPH16164A
        SABiosciences Custom PCR Arrays for TTC12 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for TTC12 gene from 5/7 species (see all 7)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    TTC121   -- tetratricopeptide repeat domain 12 83.43(n)
    78.05(a)
    479434  XM_536570.2  XP_536570.2 
    chimpanzee
    (Pan troglodytes)
    TTC121   -- tetratricopeptide repeat domain 12 98.88(n)
    98.39(a)
    451551  XM_508759.2  XP_508759.1 
    cow
    (Bos taurus)
    TTC121   -- tetratricopeptide repeat domain 12 84.21(n)
    81.17(a)
    515758  XM_593834.3  XP_593834.3 
    rat
    (Rattus norvegicus)
    Ttc121   -- tetratricopeptide repeat domain 12 81.16(n)
    77.27(a)
    300696  NM_001004246.1  NP_001004246.1 
    mouse
    (Mus musculus)
    Ttc121 , 5 9 (26.83 cM)5
    tetratricopeptide repeat domain 121, 5 80.59(n)1
    75.14(a)1
    2353301  NM_172770.21  NP_766358.11 
     AK0543505  AK0764575  (see all 8)
    About this table        Species with no ortholog for TTC12

    ENSEMBL Gene Tree for TTC12 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for TTC12 gene
    STIP12  

    TTC12 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/484 NCBI SNPs in TTC12 are shown (see all 484)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs5872901,2
    H113186231(+) tctggG/Ccaatg 1 -- int14Minor allele frequency- C:0.00NS EA 378
    rs5894531,2
    H113198396(+) GAAATT/GGTTGG 1 -- int15Minor allele frequency- G:0.00MN NS EA 604
    rs5894541,2
    H113198399(+) ATTGTT/GGGAAC 1 -- int17Minor allele frequency- G:0.00EA NA MN NS 634
    rs6265051,2
    --113190492(-) cctttC/Tcagca 1 -- int10--------
    rs6353581,2
    C,F,O,A,113197243(-) CTTAAT/ACTCGA 1 -- int123Minor allele frequency- A:0.29MN EA EU NA NS WA 1642
    rs6361491,2
    H113204972(+) TTAGCG/ATATGT 1 -- int17Minor allele frequency- A:0.00EA NA NS 480
    rs7132331,2
    C,F,A,113234466(+) CTAGCA/GCTATA 1 -- int114Minor allele frequency- T:0.03NA EA NS WA 936
    rs7198021,2
    C,F,O,A,113234679(+) GCCCTC/TGTCCC 1 -- int125Minor allele frequency- N:0.00NA EA MN NS WA 2846
    rs7198031,2
    C,F,A,113234471(+) GCTATA/GATAAC 1 -- int110Minor allele frequency- G:0.27MN NS EA NA WA 848
    rs7198041,2
    C,F,A,113234775(+) CAGCAA/GTGTTT 1 -- int121Minor allele frequency- G:0.14EA NA NS WA 3160
    About this table

    HapMap Linkage Disequilibrium images for TTC12 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TTC12: --

    QIAGEN SeqTarget long-range PCR primers for resequencing TTC12 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TTC12 for disorders           About GeneDecksing

    OMIM: 610732

    Human Genome Epidemiology (HuGE) Navigator: TTC12 (5 documents)

    Export disorders and mutations for TTC12 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/13 PubMed articles for TTC12 gene, integrated from 7 sources (see all 13):
    (articles sorted by number of sources associating them with TTC12)
    1. Identification and characterization of TPARM gene in silico. (PubMed id 12964006)1, 3, 7 Katoh M. and Katoh M. (2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. (PubMed id 20133381)1 David S.P....Eaton W.W. (2010)
    5. Haplotypic Variants in DRD2, ANKK1, TTC12, and NCAM1 are Associated With Comorbid Alcohol and Drug Dependence. (PubMed id 18828801)1 Yang B.Z....Gelernter J. (2008)
    6. Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. (PubMed id 17761687)1 Yang B.Z....Gelernter J. (2007)
    7. Hypermethylation of TTC12 gene in acute lymphoblastic leukemia. (PubMed id 17657212)1 Wattanawaraporn R....Mutirangura A. (2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. (PubMed id 17085484)1 Gelernter J....Farrer L. (2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54970 HGNC: 23700 AceView: TTC12 Ensembl:ENSG00000149292 euGenes: HUgn54970
    ECgene: TTC12 H-InvDB: TTC12

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for TTC12 gene:
    Search GeneIP for patents involving TTC12

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for TTC12 Antibodies for TTC12
     Super-pooled esiRNAs for TTC12 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for TTC12 microRNA Mimics for TTC12
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TTC12
     SeqTarget long-range PCR primers for resequencing TTC12
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TTC12
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TTC12
     GenScript Custom Purified and Recombinant Proteins Services for TTC12 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TTC12
     GenScript Custom Assay Services for TTC12 GenScript Custom Superior Antibodies Services for TTC12
     GenScript Custom overexpressing Cell Line Services for TTC12 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TTC12 promoter
     Search Chromatin IP Primers for TTC12
     RT2 qPCR Primer Assay for TTC12
     GNC Network for TTC12
     Search for Assays for microRNAs that regulate TTC12
     SABiosciences Custom PCR Arrays for TTC12
     Search Tocris compounds for TTC12
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for TTC12
     Proteins for TTC12
     Lysates for TTC12
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for TTC12
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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