Aliases &
Descriptions
for TXNDC15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| thioredoxin domain containing 151 2 | | disulfide isomerase2 | | 2310047H23Rik1 2 | | UNQ3352 | | FLJ226251 2 | | OTTHUMP000002231172 | | C5orf142 3 | | thioredoxin domain-containing protein 152 | | chromosome 5 open reading frame 141 | | |
Export aliases for TXNDC15 gene to outside databasesPrevious GC identifer: GC05P134238 |
Summaries
for TXNDC15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TXNDC15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TXNDC15
Other transcription factors
Search SABiosciences Chromatin IP Primers for TXNDC15
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TXNDC15  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1TXNDC15 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P129395: view genomic region
(about GC identifiers)
Start:
|
129,395,781 bp from pter |
End:
|
129,423,417 bp from pter |
Size:
|
27,637 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr5+ 134,209,460-134,237,323 |
RefSeq DNA sequence:- NC_000005.9 NT_034772.6
|
Proteins
for TXNDC15 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: TXD15_HUMAN, Q96J42 (See
protein sequence)Recommended Name: Thioredoxin domain-containing protein 15 precursor Size: 360 amino acids; 39885 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Caution: It is uncertain whether Met-1 or Met-13 is the initiator
Secondary accessions: Q96MT2 Q9H639Alternative splicing: 2 isoforms: Q96J42-1 Q96J42-2 Explore the universe of human proteins at neXtProt for TXNDC15: NX_Q96J42
REFSEQ proteins: NP_078991.3
ENSEMBL proteins: ENSP00000423609 ENSP00000424716 ENSP00000424220 ENSP00000424428 ENSP00000422832 ENSP00000423513 ENSP00000399854 ENSP00000351157
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
TXNDC15 for ontologies About GeneDecksing
Antibodies for TXNDC15:
Assays for TXNDC15: |
Protein
Domains/
Families
for TXNDC15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TXNDC15 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96J42ProtoNet protein and cluster: Q96J42 1 Blocks protein family: IPB006662 Thioredoxin type domain
UniProtKB/Swiss-Prot: TXD15_HUMAN, Q96J42Similarity: Contains 1 thioredoxin domain |
Gene Function
for TXNDC15 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for TXNDC15 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for TXNDC15
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TXNDC15
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0045454 | cell redox homeostasis |
IEA | -- |
About this table
TXNDC15 for ontologies About GeneDecksing
|
Drugs & Compounds
for TXNDC15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for TXNDC15
|
Transcripts
for TXNDC15 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for TXNDC15 gene: NM_024715.3 Additional cDNA sequence: AK026278.1 AK092425.1 AK225454.1 AK225462.1 AK299578.1 AK307529.1 AY358649.1 BC001615.1 BC032568.1 BX538131.1 CR601239.1 CR613338.1 CR613370.1 CR616649.1 14 DOTS entries: DT.446648 DT.100811828 DT.40132328 DT.100686768 DT.120854485 DT.100669627 DT.100811832 DT.120854478 DT.120854453 DT.40192978 DT.97796640 DT.97806613 DT.91904107 DT.95307560 24/234 AceView cDNA sequences (see all 234): BQ676344 CD513047 AI625174 CR601239 CA842809 AA878057 BE673389 Z40855 W47023 BU163418 AL710291 AI580766 AA737338 BM673580 BI715332 BQ682086 BM661510 BQ683964 BM932055 AW513555 BQ447928 BM926232 BQ682436 AI955245 Unigene Cluster for TXNDC15: Thioredoxin domain containing 15 Hs.728217 [show with all ESTs]Unigene Representative Sequence: NM_024715
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TXNDC15 (see all 8)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for TXNDC15
11 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000511070 ENST00000505174 ENST00000507024 ENST00000506916 ENST00000506350
ENST00000508810 ENST00000509954 ENST00000508779 ENST00000441965(uc010jdy.1 uc003lac.1)
ENST00000358387(uc011cxv.1) ENST00000502625
|
Expression
for TXNDC15 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| TXNDC15 expression in normal and diseased human tissues
1 / 2 6 probe-sets matching TXNDC15 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 56351_at2
|
U95-B |
1 |
1.00 |
1.00 |
0.76 |
0.93 |
-- |
-- |
-- |
-- |
-- |
| 56353_at2
|
U95-B |
1 |
0.88 |
1.00 |
0.79 |
1.07 |
-- |
-- |
-- |
-- |
-- |
| 220495_s_at2
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 227873_at2
|
U133-B |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 220495_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 227873_at2
|
U133Plus2 |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
TXNDC15 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TGTGTACTTA
SOURCE GeneReport for Unigene cluster: Hs.728217
SABiosciences Custom PCR Arrays for TXNDC15
|
Orthologs
for TXNDC15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for TXNDC15 gene from 5/10 species (see all 10)
About this table Species with no ortholog for TXNDC15
ENSEMBL Gene Tree for TXNDC15 (if available) |
Paralogs
for TXNDC15 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for TXNDC15 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 5 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for TXNDC15 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TXNDC15
1 CNV: 4479 |
Disorders & Mutations
for TXNDC15 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for TXNDC15 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for TXNDC15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10 PubMed articles for TXNDC15 gene integrated from 7 sources:
(articles sorted by number of sources associating them with TXNDC15)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
- Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1 Gudbjartsson D.F....Stefansson K. (2008)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1 Zhang H.... Aebersold R. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149)1 Suzuki Y.... Sugano S. (1997)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for TXNDC15 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TXNDC15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TXNDC15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TXNDC15 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TXNDC15 gene:
Search GeneIP for patents involving TXNDC15
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TXNDC15 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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