Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS
Search by expression pattern Search by expression pattern


TXNL1 Gene

protein-coding   GIFtS: 51

GC18M050981
thioredoxin-like 1
(Previous names: thioredoxin-like, 32kDa )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: TXNL)
Products    

Aliases &
Descriptions
for TXNL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
thioredoxin-like 11 2     thioredoxin-like protein 12
TRP321 2 3     thioredoxin-related protein 12
Txl1 2     TXL-12
32 kDa thioredoxin-related protein2 3     thioredoxin-related 32 kDa protein2
TXNL2 3     TXL3
thioredoxin-like, 32kDa1     

External Ids:    HGNC: 124361   Entrez Gene: 93522   Ensembl: ENSG000000911647   UniProtKB: O433963   

Export aliases for TXNL1 gene to outside databases

Previous GC identifers: GC18M052420 GC18M052421 GC18M054264


Summaries
for TXNL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Gene Wiki entry for TXNL1

Genomic Views
for TXNL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TXNL1 gene promoter:
         AP-1   GCNF-1   GCNF-2   COUP-TF1   HNF-4alpha2   RFX1   TGIF   deltaCREB   CREB   ATF-2   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for TXNL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TXNL1 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.31   Ensembl cytogenetic band:  18q21.31   HGNC cytogenetic band: 18q21.31

TXNL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TXNL1 gene location

GeneLoc gene densities for chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M050981:  view genomic region     (about GC identifiers)

Start:
 50,981,411 bp from pter
End:
 51,017,287 bp from pter
Size:
 35,877 bases
Orientation:
 minus strand

1 alternative location:
Chr18- 54,264,439-54,305,920     
RefSeq DNA sequence:
NC_000018.9  NT_025028.14  

Proteins
for TXNL1 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: TXNL1_HUMAN, O43396 (See protein sequence)
Recommended Name: Thioredoxin-like protein 1  
Size: 289 amino acids; 32251 Da
Subcellular location: Cytoplasm
PDB structure from and Proteopedia :
1GH2 (3D)    1WWY (3D)    

Explore the universe of human proteins at neXtProt for TXNL1: NX_O43396 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_004777.1  

    ENSEMBL proteins: 
    ENSP00000217515 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: TXNL1
    OriGene Protein Over-expression Lysate: TXNL1
    GenScript Custom Purified and Recombinant Proteins Services for TXNL1 
    Novus Biologicals Protein for TXNL1
    Novus Biologicals Lysate for TXNL1
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IDA9668102
    About this table

    TXNL1 for ontologies           About GeneDecksing



    Antibodies for TXNL1: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for TXNL1
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for TXNL1 
    Novus Biologicals Antibodies for TXNL1
    Browse antibodies at Epitomics

    Assays for TXNL1: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TXNL1 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TXNL1 

    Protein Domains/
    Families
    for TXNL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TXNL1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR005746 Thioredoxin
     IPR012336 Thioredoxin-like_fold
     IPR008979 Galactose-bd-like
     IPR010400 Proteasome-int_thioredoxin_C
     IPR012335 Thioredoxin_fold

    Graphical View of Domain Structure for InterPro Entry O43396

    ProtoNet protein and cluster: O43396

    1 Blocks protein family: IPB006662 Thioredoxin type domain

    UniProtKB/Swiss-Prot: TXNL1_HUMAN, O43396
    Similarity: Contains 1 thioredoxin domain


    Gene Function
    for TXNL1 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for TXNL1
    Sigma-Aldrich shRNA for TXNL1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): TXNL1
    OriGene shRNA RFP (see all 2): TXNL1
    OriGene basic RS shRNA (see all 2): TXNL1
    OriGene siRNA (see all 2): TXNL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TXNL1 
    miRNA:Sigma-Aldrich microRNA Mimics for TXNL1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TXNL1 
    1 SABiosciences Assays for microRNA that regulate TXNL1:
    hsa-miR-665

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TXNL1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TXNL1
    OriGene untagged cDNA clones in CMV expression vector (see all 2): TXNL1
    OriGene 3'-UTR clone: TXNL1 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for TXNL1 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for TXNL1 

    3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009055 electron carrier activity IEA--
    GO:0015035 protein disulfide oxidoreductase activity IEA--
    GO:0015036 disulfide oxidoreductase activity IDA9668102
    About this table

    TXNL1 for ontologies           About GeneDecksing


    Pathways & Interactions
    for TXNL1 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for TXNL1 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TXNL1

    4 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006662 glycerol ether metabolic process IEA--
    GO:0006810 transport IEA--
    GO:0022900 electron transport chain IEA--
    GO:0045454 cell redox homeostasis IEA--
    About this table

    TXNL1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TXNL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    TXNL1 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TXNL1
    1 Novoseek chemical compound relationship for TXNL1 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glucose 15.6 1 16438969 (1)
    About this table



    Transcripts
    for TXNL1 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for TXNL1
    Sigma-Aldrich shRNA for TXNL1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): TXNL1
    OriGene shRNA RFP (see all 2): TXNL1
    OriGene basic RS shRNA (see all 2): TXNL1
    OriGene siRNA (see all 2): TXNL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TXNL1 
    miRNA: Sigma-Aldrich microRNA Mimics for TXNL1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TXNL1 
    1 SABiosciences Assays for microRNA that regulate TXNL1:
    hsa-miR-665
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: TXNL1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: TXNL1
    OriGene untagged cDNA clones in CMV expression vector (see all 2): TXNL1
    OriGene 3'-UTR Clone: TXNL1 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for TXNL1 
    Primers: OriGene genome-wide validated SYBR primer pairs: TXNL1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TXNL1: PPH11290A

    REFSEQ mRNAs for TXNL1 gene: 

    NM_004786.2  

    Additional cDNA sequence: 

    AB209263.1 AF003938.1 AF051896.1 AF052659.1 AK094926.1 AK313653.1 BC001156.1 BX640857.1 
    CR615108.1 

    13 DOTS entries:

    DT.453897  DT.92407349  DT.91850846  DT.451926  DT.95188792  DT.75157992  DT.100644040  DT.91858889 
    DT.100815998  DT.40221703  DT.92440791  DT.95188791  DT.92326962 

    24/320 AceView cDNA sequences (see all 320):

    BM551063 AV728382 AA743739 C00325 AA583443 BX111174 BE887614 W72866 
    AI339963 BM928276 AW474814 AF052659 CB128664 CD368419 BQ231905 AF051896 
    AI590701 BF438586 CD365235 BQ229551 CB240660 BQ441126 AA600928 AA845477 

    highest scoring ESTs for TXNL1:

    AF003938 AA187791 AA196641 AA233945 AA255638 AA285186 AA314445 AA350950 AA370369 AA374382 

    Unigene Cluster for TXNL1:

    Thioredoxin-like 1
    Hs.114412  [show with all ESTs]
    Unigene Representative Sequence: BX640857


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TXNL1 (see all 6)

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                                              -                                         -         
    SP2:                                                              -                                                   
    SP3:                                                                                                                  
    SP4:                                                                                                                  
    SP5:                    -                                                                                             

    About this scheme

    ECgene alternative splicing isoforms for TXNL1
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000217515(uc010xdz.1 uc002lgg.2 uc002lgh.2 uc002lgi.2 uc002lgj.1)


    Expression
    for TXNL1 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    TXNL1 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching TXNL1 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32214_at2, 3 U95-A 1 0.56 1.00 0.59 1.09 AF003938 1.00 1.00 1.00 1
    85723_at2 U95-E 1 0.50 1.00 0.97 0.95 -- -- -- -- --
    79933_at2 U95-E 1 0.44 1.00 0.94 0.98 -- -- -- -- --
    201588_at2, 3 U133-A 1 0.55 1.00 -- -- NM_004786 0.60 1.00 0.82 1
    235561_at2 U133-B 1 0.27 1.00 -- -- -- -- -- -- --
    201588_at2 U133Plus2 1 0.55 1.00 -- -- -- -- -- -- --
    235561_at2 U133Plus2 1 0.27 1.00 -- -- -- -- -- -- --
    About this table

    TXNL1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    TXNL1 gene expression
    TXNL1 gene electronic northern expression
    TXNL1 gene sage expression
    About these images

    CGAP SAGE TAG: CAATTGTAAA

    SOURCE GeneReport for Unigene cluster: Hs.114412

    Expression variation in blood from EXPOLDB for TXNL1

    UniProtKB/Swiss-Prot: TXNL1_HUMAN, O43396
    Tissue specificity: Ubiquitous

    Primers: OriGene genome-wide validated SYBR primer pairs: TXNL1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for TXNL1: PPH11290A
        SABiosciences Custom PCR Arrays for TXNL1 


    Orthologs
    for TXNL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for TXNL1 gene from 5/18 species (see all 18)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 TXNL11   -- thioredoxin-like 1 95.46(n)
    98.83(a)    		 483970  XM_541090.2  XP_541090.2 
    chimpanzee
    (Pan troglodytes)    		 TXNL11   -- thioredoxin-like 1 99.88(n)
    100(a)    		 455433  XM_001137413.1  XP_001137413.1 
    cow
    (Bos taurus)    		 TXNL11   -- thioredoxin-like 1 94.4(n)
    99.64(a)    		 509142  XM_001249359.1  XP_001249360.1 
    rat
    (Rattus norvegicus)    		 Txnl11   -- thioredoxin-like 1 92.39(n)
    98.96(a)    		 140922  NM_080887.2  NP_543163.1 
    mouse
    (Mus musculus)    		 Txnl11 , 5 18 (37.06 cM)5
    		 thioredoxin-like 11, 5 92.73(n)1
    98.62(a)1    		 533821  NM_016792.31  NP_058072.21 
     AF0526605  AK0298075  (see all 23)
    About this table        Species with no ortholog for TXNL1

    ENSEMBL Gene Tree for TXNL1 (if available)

    Paralogs
    for TXNL1 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for TXNL1 gene
    TXNDC82  TXN2  TXNDC22  

    TXNL1 for paralogs           About GeneDecksing



    Genomic Variants
    for TXNL1 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/374 NCBI SNPs in TXNL1 are shown (see all 374)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 18 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs4815221,2
    		C,F,O,H,54289867(+) CATTTT/CTTCCT 1 -- int110Minor allele frequency- C:0.07EA NA NS 704
    rs4834051,2
    		C,F,O,A,54304178(+) CATCAC/AAAAAT 1 -- int115Minor allele frequency- A:0.17NS NA EA WA 790
    rs5013551,2
    		C,F,O,A,54276448(+) tgctAT/CCATAT 1 -- int113Minor allele frequency- C:0.41NS EA NA WA 774
    rs5226881,2
    		C54273382(-) TGATCC/AGCCCG 1 -- int15Minor allele frequency- A:0.00NS EA NA 422
    rs5360061,2
    		C,F,O,H,54284028(+) TCTTAC/TAGCTC 1 -- int114Minor allele frequency- T:0.07NS EA NA WA 622
    rs5405001,2
    		C,F,H,54302527(-) GGATCT/CCTGCT 1 -- int112Minor allele frequency- C:0.01NS EA NA WA 482
    rs5448661,2
    		C54299172(+) aaGGAA/CCCCAC 1 -- int1 trp36Minor allele frequency- C:0.00EA NA NS 442
    rs5832931,2
    		H54298777(+) TAAAAT/AGTGTA 1 -- int14Minor allele frequency- A:0.00NS EA 418
    rs5861571,2
    		C,F,O,54306276(+) CTACAC/TACAAG 1 -- ng5118Minor allele frequency- T:0.04NA EA MN NS WA 882
    rs5917831,2
    		--54270528(-) tatttA/Taaaaa 1 -- int1 trp30--------
    About this table

    HapMap Linkage Disequilibrium images for TXNL1 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TXNL1: --

    QIAGEN SeqTarget long-range PCR primers for resequencing TXNL1 

    Disorders & Mutations
    for TXNL1 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TXNL1 for disorders           About GeneDecksing

    OMIM: 603049

    Human Genome Epidemiology (HuGE) Navigator: TXNL1 (1 document)

    Export disorders and mutations for TXNL1 gene to outside databases

    Medical News
    for TXNL1 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for TXNL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/21 PubMed articles for TXNL1 gene, integrated from 7 sources (see all 21):
    (articles sorted by number of sources associating them with TXNL1)
    1. Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa. (PubMed id 9668102)1, 2, 3, 7 Lee K.-K.... Yonehara S. (1998)
    2. Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein. (PubMed id 9473519)1, 2, 3, 7 Miranda-Vizuete A.... Spyrou G. (1998)
    3. Genomic structure and chromosomal localization of human thioredoxin- like protein gene (txl). (PubMed id 10826702)1, 2, 7 Miranda-Vizuete A. and Spyrou G. (2000)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    6. Crystal structure of the catalytic domain of a human thioredoxin-like protein. (PubMed id 11985582)1, 2 Jin J.... Yuan J. (2002)
    7. Thioredoxin Txnl1/TRP32 Is a Redox-active Cofactor of the 26 S Proteasome. (PubMed id 19349277)1, 7 Andersen K.M....Hartmann-Petersen R. (2009)
    8. Characterization of human thioredoxin-like-1: potential involvement in the cellular response against glucose deprivation. (PubMed id 16438969)1, 7 Jimenez A....Miranda-Vizuete A. (2006)
    9. Solution structure of the C-terminal DUF1000 domain o f the human thioredoxin-like 1 protein. (PubMed id 20455272)1, 7 Goroncy A.K....Yokoyama S. (2010)
    10. Thioredoxin-related Protein 32 is an arsenite-regulat ed Thiol Reductase of the proteasome 19 S particle. (PubMed id 19349280)1 Wiseman R.L....Ron D. (2009)

    External Searches for TXNL1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TXNL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9352 HGNC: 12436 AceView: TXNL1 Ensembl:ENSG00000091164 euGenes: HUgn9352
    ECgene: TXNL1 H-InvDB: TXNL1

    Other Databases showing TXNL1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TXNL1 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for TXNL1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for TXNL1 gene:
    Search GeneIP for patents involving TXNL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for TXNL1 gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for TXNL1 Antibodies for TXNL1
     Super-pooled esiRNAs for TXNL1 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for TXNL1 microRNA Mimics for TXNL1
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of TXNL1
     SeqTarget long-range PCR primers for resequencing TXNL1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for TXNL1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of TXNL1
     GenScript Custom Purified and Recombinant Proteins Services for TXNL1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TXNL1
     GenScript Custom Assay Services for TXNL1 GenScript Custom Superior Antibodies Services for TXNL1
     GenScript Custom overexpressing Cell Line Services for TXNL1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TXNL1 promoter
     Search Chromatin IP Primers for TXNL1
     RT2 qPCR Primer Assay for TXNL1
     Search GNC Networks for TXNL1
     Assays for microRNAs that regulate TXNL1
     SABiosciences Custom PCR Arrays for TXNL1
     Search Tocris compounds for TXNL1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for TXNL1
     Proteins for TXNL1
     Lysates for TXNL1
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for TXNL1
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

    View Random Gene

    Category
    GIFtS Group
    The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    TXNL1 gene at Home site.
    hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4