Aliases &
Descriptions
for UBAC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| UBA domain containing 21 2 | | PHGDHL12 3 | | RP11-178C10.11 2 | | FLJ424132 | | FLJ305481 2 | | FLJ263512 | | phosphoglycerate dehydrogenase like 11 2 | | MGC904872 | | Phosphoglycerate dehydrogenase-like protein 12 3 | | FLJ300012 | | UBA domain-containing protein 22 3 | | ubiquitin-associated domain-containing protein 22 |
Export aliases for UBAC2 gene to outside databasesPrevious GC identifers: GC13P098652 GC13P099852 |
Summaries
for UBAC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for UBAC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for UBAC2
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBAC2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for UBAC2  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q32.3 Ensembl cytogenetic band: 13q32.3 HGNC chromosome: 13UBAC2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P080447: view genomic region
(about GC identifiers)
Start:
|
80,446,903 bp from pter |
End:
|
80,633,071 bp from pter |
Size:
|
186,169 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr13+ 99,853,028-100,038,688 |
RefSeq DNA sequence:- NC_000013.10 NT_009952.14
|
Proteins
for UBAC2 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: UBAC2_HUMAN, Q8NBM4 (See
protein sequence)Recommended Name: Ubiquitin-associated domain-containing protein 2 precursor Size: 344 amino acids; 38964 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAH72674.1; Type=Erroneous initiation; Sequence=AAI21139.1; Type=Erroneous initiation;
Secondary accessions: B3KNV7 Q0VAB5 Q5W0W6 Q5W0W9 Q6GQR2 Q6P4B0 Q8N2E8 Q96NW2Alternative splicing: 5 isoforms: Q8NBM4-1 Q8NBM4-2 Q8NBM4-3 Q8NBM4-4 Q8NBM4-5 Explore the universe of human proteins at neXtProt for UBAC2: NX_Q8NBM4
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_001137544.1 NP_808882.1
ENSEMBL proteins: ENSP00000365623 ENSP00000383911 ENSP00000402249 ENSP00000317007 ENSP00000347928
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
UBAC2 for ontologies About GeneDecksing
Antibodies for UBAC2:
Assays for UBAC2: |
Protein
Domains/
Families
for UBAC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBAC2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NBM4ProtoNet protein and cluster: Q8NBM4 1 Blocks protein family: IPB000449 Ubiquitin-associated domain
UniProtKB/Swiss-Prot: UBAC2_HUMAN, Q8NBM4Similarity: Contains 1 UBA domain |
Gene Function
for UBAC2 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for UBAC2 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for UBAC2
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBAC2
2 Interacting proteins for UBAC2 (Q8NBM42) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for UBAC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for UBAC2
|
Transcripts
for UBAC2 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for UBAC2 gene (2 alternative transcripts): NM_001144072.1 NM_177967.3 Additional cDNA sequence: AF339812.1 AK054563.1 AK055110.1 AK075419.1 AK075516.1 AK124404.1 AK129861.1 AK290342.1 AK300908.1 BC053346.1 BC063559.1 BC072674.1 BC121138.1 BC121139.1 BC143265.1 CR611931.1 24/25 DOTS entries (see all 25): DT.308044 DT.100053302 DT.100689946 DT.92444187 DT.120766107 DT.95357803 DT.100059925 DT.100059933 DT.100689974 DT.100856863 DT.319660 DT.95071980 DT.120766033 DT.120766190 DT.95296291 DT.100837233 DT.120766158 DT.120766203 DT.120765992 DT.100645794 DT.120766145 DT.120766224 DT.92425917 DT.92444190 24/455 AceView cDNA sequences (see all 455): BQ888551 BU616137 CR611931 BM840865 BM051478 BM669559 BU947529 CF141604 AW518909 BQ676282 AI866141 BU845782 AA279318 BU931687 BM766191 BU859336 AW002178 BI823954 BM743421 CB132292 BQ685932 AA614853 BU838272 BX395933 Unigene Cluster for UBAC2: UBA domain containing 2 Hs.508545 [show with all ESTs]Unigene Representative Sequence: NM_001144072
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for UBAC2 (see all 12)
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | · | 2g | · | 2h | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14a | · | 14b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for UBAC2
12 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000376440 ENST00000403766 ENST00000468067 ENST00000473091 ENST00000460562
ENST00000474510 ENST00000480738 ENST00000494576(uc001voh.2) ENST00000473194
ENST00000457666 ENST00000325028(uc001voa.3 uc010tiu.1 uc001vob.3 uc010tiv.1 uc001vod.2 uc001voc.2 uc010tiw.1)
ENST00000355700
|
Expression
for UBAC2 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| UBAC2 expression in normal and diseased human tissues
1 / 2 3 probe-sets matching UBAC2 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 57064_at2
|
U95-B |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
| 224298_s_at2
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 224298_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
UBAC2 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AAAAGACCCG
SOURCE GeneReport for Unigene cluster: Hs.508545
SABiosciences Custom PCR Arrays for UBAC2
|
Orthologs
for UBAC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for UBAC2 gene from 5/9 species (see all 9)
About this table Species with no ortholog for UBAC2
ENSEMBL Gene Tree for UBAC2 (if available) |
Paralogs
for UBAC2 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for UBAC2 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 13 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for UBAC2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for UBAC2
1 Inversion: 59717 | | QIAGEN SeqTarget long-range PCR primers for resequencing UBAC2 |
|
Disorders & Mutations
for UBAC2 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBAC2 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: UBAC2 (2 documents)
Export disorders and mutations for UBAC2 gene to outside databases
|
Medical News
for UBAC2 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for UBAC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
8 PubMed articles for UBAC2 gene integrated from 7 sources:
(articles sorted by number of sources associating them with UBAC2)- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia. (PubMed id 11991713)1 Christian S.L....Gershon E.S. (2002)
|
External Searches for UBAC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBAC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBAC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBAC2 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for UBAC2 gene:
Search GeneIP for patents involving UBAC2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBAC2 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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