Aliases &
Descriptions
for UBOX5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| U-box domain containing 51 2 | | UBCE7IP52 3 | | KIAA08601 2 3 | | U-box domain-containing protein 52 3 | | RNF371 2 3 | | Ubce7ip51 | | UIP51 2 | | RING finger protein 372 | | Ubiquitin-conjugating enzyme 7-interacting protein 52 3 | | ubiquitin conjugating enzyme 7 interacting protein 52 |
Export aliases for UBOX5 gene to outside databasesPrevious GC identifers: GC20M003039 GC20M003040 GC20M003041 GC20M003042 GC20M003043 GC20M003044 GC20M003045 GC20M003046 GC20M003047 GC20M003048 GC20M003049 |
Summaries
for UBOX5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for UBOX5 |
Genomic Views
for UBOX5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBOX5 gene promoter:
SREBP-1c SREBP-1a SREBP-1b Tal-1beta ITF-2 Meis-1 HOXA9B CUTL1 GATA-1 NF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBOX5
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for UBOX5  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13UBOX5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M003088: view genomic region
(about GC identifiers)
Start:
|
3,036,163 bp from pter |
End:
|
3,140,842 bp from pter |
Size:
|
104,680 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000020.10 NT_011387.8
|
Proteins
for UBOX5 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: RNF37_HUMAN, O94941 (See
protein sequence)Recommended Name: RING finger protein 37 Size: 541 amino acids; 58966 Da
Subunit: Interacts with UBE2L3 (By similarity)
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=BAA74883.2; Type=Erroneous initiation;
Secondary accessions: Q6IAR5Explore the universe of human proteins at neXtProt for UBOX5: NX_O94941
REFSEQ proteins (2 alternative transcripts):
NP_055763.1 NP_955447.1
ENSEMBL proteins: ENSP00000415922 ENSP00000404364 ENSP00000311726 ENSP00000217173
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000151 | ubiquitin ligase complex |
IEA | -- | | GO:0005634 | nucleus |
IEA | -- |
About this table
UBOX5 for ontologies About GeneDecksing
Antibodies for UBOX5:
Assays for UBOX5: |
Protein
Domains/
Families
for UBOX5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBOX5 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O94941ProtoNet protein and cluster: O94941 2 Blocks protein families: IPB001841 Zn-finger IPB003613 Zn-finger
UniProtKB/Swiss-Prot: RNF37_HUMAN, O94941Similarity: Contains 1 RING-type zinc fingerSimilarity: Contains 1 U-box domain |
Gene Function
for UBOX5 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
5 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
UBOX5 for ontologies About GeneDecksing
|
Pathways & Interactions
for UBOX5 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
UBOX5 for pathways About GeneDecksing
1  Kegg Pathway (Kegg details for UBOX5):
SABiosciences Custom Pathway-Focused PCR Arrays for UBOX5
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBOX5
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000209 | protein polyubiquitination |
IEA | -- | | GO:0016567 | protein ubiquitination |
-- | -- |
About this table
UBOX5 for ontologies About GeneDecksing
|
Drugs & Compounds
for UBOX5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for UBOX5
|
Transcripts
for UBOX5 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for UBOX5 gene (2 alternative transcripts): NM_014948.2 NM_199415.1 Additional cDNA sequence: AB020667.1 AK022444.1 AK023211.1 AK222570.1 AK222876.1 AK301748.1 BC000515.2 BC007413.2 BC011856.1 BC046122.1 BC064544.1 CR457089.1 CR593540.1 XR_078902.1 8 DOTS entries: DT.86835779 DT.213203 DT.100783984 DT.92049475 DT.92427815 DT.100703439 DT.100783983 DT.120804313 24/218 AceView cDNA sequences (see all 218): AI280555 CD676820 AW516198 BQ062115 AI470602 BE673075 BM983023 BM672562 BX492152 BQ059605 BM980040 BQ643186 BI490972 AA465631 CR593540 NM_014948 BM480008 AW134699 AK023211 AU129412 BC064544 BM927457 BQ423809 BQ642543
 highest scoring ESTs for UBOX5:AB020667 AK022444 AL520515 AU099495 AU122539 AW245534 BC000515 BC046122 BC064544 BE974194 Unigene Cluster for UBOX5: U-box domain containing 5 Hs.654646 [show with all ESTs]Unigene Representative Sequence: NM_014948
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for UBOX5 (see all 7)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for UBOX5
4 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000440298 ENST00000449731 ENST00000348031(uc002whx.2) ENST00000217173(uc002whw.2 uc002why.1)
|
Expression
for UBOX5 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| UBOX5 expression in normal and diseased human tissues
1 / 2 / 3 5 probe-sets matching UBOX5 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 35161_at2, 3
|
U95-A |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
AB020667 |
1.00 |
0.80 |
0.91 |
1 |
| 215544_s_at2
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 204598_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_014948 |
0.60 |
0.83 |
0.73 |
1 |
| 215544_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 204598_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
UBOX5 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TTACTCTTAG
SOURCE GeneReport for Unigene cluster: Hs.654646
Expression variation in blood from EXPOLDB for UBOX5 SABiosciences Custom PCR Arrays for UBOX5
|
Orthologs
for UBOX5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for UBOX5 gene from 5/10 species (see all 10)
About this table Species with no ortholog for UBOX5
ENSEMBL Gene Tree for UBOX5 (if available) |
Paralogs
for UBOX5 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for UBOX5 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 20 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for UBOX5 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for UBOX5
2 CNVs: 6047 5121 | | QIAGEN SeqTarget long-range PCR primers for resequencing UBOX5 |
|
Disorders & Mutations
for UBOX5 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for UBOX5 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for UBOX5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/12 PubMed articles for UBOX5 gene, integrated from 7 sources (see all 12):
(articles sorted by number of sources associating them with UBOX5)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes. (PubMed id 11274149)1, 3 Pringa E....Harbers K. (2001)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T....Ohara O. (1998)
- Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (2009)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Interaction of U-box-type ubiquitin-protein ligases ( E3s) with molecular chaperones. (PubMed id 15189447)1 Hatakeyama S....Nakayama K.I. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. (PubMed id 10431818)1 Martinez-Noel G....Harbers K. (1999)
|
External Searches for UBOX5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBOX5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBOX5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing UBOX5 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for UBOX5 gene:
Search GeneIP for patents involving UBOX5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBOX5 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
 |
 |
| | |
 |  |  |  | |
| |  | Search Tocris compounds for UBOX5 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for UBOX5 |
| |
|
|
