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UBXN11 Gene

protein-coding GIFtS: 44

GC01M024865

UBX domain protein 11
(Previous name: UBX domain containing 5 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: UBXD5)

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
UBX domain protein 11¹ ²		UBX domain-containing protein 11²
SOC¹ ² ³		OTTHUMP00000003562²
SOCI¹ ²		colorectal tumor-associated antigen-1²
UBX domain containing 5¹ ²		COA-1²
Colorectal tumor-associated antigen COA-1² ³		socius²
UBXD5² ³		DKFZp686F04228²
UBX domain-containing protein 5² ³		Socius³

External Ids:	HGNC: 30600¹	Entrez Gene: 91544²	Ensembl: ENSG00000158062⁷	UniProtKB: Q5T124³

Export aliases for UBXN11 gene to outside databases

Previous GC identifers: GC01M026481 GC01M026607

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UBXN11:

This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with

members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts

with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is

proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling

pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several

transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding

different isoforms have been found for this gene. (provided by RefSeq)

UniProtKB/Swiss-Prot: UBX11_HUMAN, Q5T124

Function: May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA

activation mediated by GNA12 and GNA13 (By similarity)

Gene Wiki entry for UBXN11 (UBXD5)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for UBXN11
Other transcription factors

Search SABiosciences Chromatin IP Primers for UBXN11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for UBXN11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p36.11

UBXN11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBXN11 gene location

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M024865: view genomic region (about GC identifiers)

Start:	24,863,104 bp from pter
End:	24,898,855 bp from pter
Size:	35,752 bases
Orientation:	minus strand

1 alternative location:

Chr1- 26,607,819-26,644,854

RefSeq DNA sequence:

NC_000001.10 NT_004610.19

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: UBX11_HUMAN, Q5T124 (See protein sequence)

Recommended Name: UBX domain-containing protein 11

Size: 520 amino acids; 57373 Da

Subunit: Interacts with GNA12, GNA13, RND1, RND2 AND RND3 (By similarity)

Subcellular location: Cytoplasm, cytoskeleton (By similarity)

Sequence caution: Sequence=AAM74202.1; Type=Frameshift; Positions=190; Sequence=AAQ15261.1; Type=Frameshift;

Positions=390; Sequence=CAI15828.1; Type=Erroneous gene model prediction;

Secondary accessions: Q5T117 Q5T120 Q5T125 Q5T126 Q5T129 Q5T131 Q5T133 Q63HM6 Q71RB3 Q8IY27 Q8N1L6

Q8N9M4 Q8NA18 Q8NFE3 Q8NFE4 Q8NFE6

Alternative splicing: 8 isoforms: Q5T124-1 Q5T124-2 Q5T124-3 Q5T124-4 Q5T124-5 Q5T124-6 Q5T124-7 Q5T124-8

Explore the universe of human proteins at neXtProt for UBXN11: NX_Q5T124

REFSEQ proteins (3 alternative transcripts):

NP_001070730.1 NP_663320.2 NP_892120.2

ENSEMBL proteins:

ENSP00000404956 ENSP00000363332 ENSP00000363339 ENSP00000363340 ENSP00000373887 ENSP00000393858

ENSP00000363334 ENSP00000395165 ENSP00000413448 ENSP00000394036 ENSP00000410357 ENSP00000349601

ENSP00000363338 ENSP00000324721

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates
	GenScript Custom Purified and Recombinant Proteins Services for UBXN11
	Novus Biologicals Protein for UBXN11
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--

About this table

UBXN11 for ontologies About GeneDecksing

Antibodies for UBXN11:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for UBXN11
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies
	GenScript Custom Superior Antibodies Services for UBXN11
	Browse antibodies at Epitomics

Assays for UBXN11:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for UBXN11
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UBXN11 for domains About GeneDecksing

2 InterPro domains/families:

IPR012989 SEP_domain

IPR001012 UBX

Graphical View of Domain Structure for InterPro Entry Q5T124

ProtoNet protein and cluster: Q5T124

2 Blocks protein families:

IPB001012 UBX domain

IPB012989 SEP

UniProtKB/Swiss-Prot: UBX11_HUMAN, Q5T124

Similarity: Contains 1 SEP domain

Similarity: Contains 1 UBX domain

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: UBX11_HUMAN, Q5T124

Function: May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA

activation mediated by GNA12 and GNA13 (By similarity)

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for UBXN11 Sigma-Aldrich shRNA for UBXN11
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 6): UBXN11 OriGene shRNA RFP (see all 6): UBXN11 OriGene basic RS shRNA (see all 6): UBXN11 OriGene siRNA (see all 3): UBXN11
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UBXN11

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UBXN11
		Search SABiosciences for Assays for microRNAs that regulate UBXN11

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): UBXN11 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): UBXN11 OriGene untagged cDNA clones in CMV expression vector (see all 6): UBXN11 Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for UBXN11
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for UBXN11

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for UBXN11

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for UBXN11

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

UBXN11 for compounds About GeneDecksing

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UBXN11
5 Novoseek chemical compound relationships for UBXN11 gene

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
pyridinoline	59.9	2	15108060 (1), 10543415 (1)
deoxypyridinoline	55.5	2	15108060 (1), 10543415 (1)
calcium	37.4	3	15653003 (1), 15108060 (1), 10560127 (1)
creatinine	25.9	4	8988349 (2), 15108060 (1), 15634535 (1)
zinc	12.6	1	15978968 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for UBXN11 Sigma-Aldrich shRNA for UBXN11
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 6): UBXN11 OriGene shRNA RFP (see all 6): UBXN11 OriGene basic RS shRNA (see all 6): UBXN11 OriGene siRNA (see all 3): UBXN11
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UBXN11

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UBXN11
		Search SABiosciences for Assays for microRNAs that regulate UBXN11

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): UBXN11 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): UBXN11 OriGene untagged cDNA clones in CMV expression vector (see all 6): UBXN11 Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for UBXN11

Primers:		OriGene genome-wide validated SYBR primer pairs: UBXN11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for UBXN11: PPH12541A

REFSEQ mRNAs for UBXN11 gene (3 alternative transcripts):

NM_001077262.1 NM_145345.2 NM_183008.2

Additional cDNA sequence:

AF370425.1 AF520989.1 AF521017.1 AF521018.1 AK074358.1 AK090792.1 AK093258.1 AK094198.1

AK097368.1 AK291503.1 AK293910.1 AK296179.1 AY007163.1 BX647774.1 CR590200.1 CR612365.1

CR625017.1

24/37 DOTS entries (see all 37):

DT.91748768 DT.100704917 DT.121392201 DT.40130545 DT.100887409 DT.100887414 DT.100694612 DT.446042

DT.91748764 DT.100887411 DT.102828970 DT.121392310 DT.121392270 DT.100686630 DT.100887415 DT.100887405

DT.100653292 DT.100887408 DT.102828971 DT.219230 DT.95097544 DT.102828968 DT.121392221 DT.121392274

24/162 AceView cDNA sequences (see all 162):

BX342903 BM021425 AK094198 BM725081 BI760900 BI770475 AW515070 BI826860

BX280347 CR625017 CR590200 BX403402 BI767071 CB216028 CR612365 BP368946

BI820771 AL555488 BM987787 BU688306 BX329336 BI464360 BM919885 AK093258

Unigene Cluster for UBXN11:

UBX domain protein 11

Hs.145061 [show with all ESTs]

Unigene Representative Sequence: BX647774

GeneLoc Exon Structure

5/21 Alternative Splicing Database (ASD) splice patterns (SP) for UBXN11 (see all 21)

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	^	7	^	8a	·	8b	^	9	^	10a	·	10b	·	10c	·	10d	^	11a	·	11b	·	11c	^	12	^	13a	·
SP1:															-														-																		-				-
SP2:									-						-														-																						-
SP3:									-						-		-												-																		-				-
SP4:															-		-												-				-														-				-
SP5:																													-

ExUns:	13b	^	14	^	15	^	16
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for UBXN11
18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):

ENST00000442942 ENST00000374215 ENST00000374222(uc001bly.2) ENST00000374223

ENST00000486658 ENST00000389235 ENST00000494942 ENST00000436301 ENST00000472155(uc001blv.2 uc001bmb.1 uc010ofb.1 uc010ofc.1)

ENST00000374217(uc001blz.1 uc001blx.2 uc001bma.2) ENST00000421827

ENST00000450041 ENST00000423664 ENST00000452980 ENST00000357089 ENST00000496466

ENST00000374221(uc001blw.2) ENST00000475591

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

UBXN11 expression in normal and diseased human tissues

¹ / ²

3 probe-sets matching UBXN11 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
58233_at²	U95-B	1	0.94	1.00	1.00	1.00	--	--	--	--	--
227716_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
227716_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

UBXN11 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

UBXN11 gene electronic northern expression

About these images

CGAP SAGE TAG: GATGCCTCTG

SOURCE GeneReport for Unigene cluster: Hs.145061

Primers:		OriGene genome-wide validated SYBR primer pairs: UBXN11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for UBXN11: PPH12541A

SABiosciences Custom PCR Arrays for UBXN11

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for UBXN11 gene from 5/6 species (see all 6)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBXN11¹	--	UBX domain protein 11	84.68(n) 80.54(a)	487356 XM_544482.2 XP_544482.2
chimpanzee (Pan troglodytes)	UBXN11¹	--	UBX domain protein 11	98.6(n) 98(a)	456657 XM_001141194.1 XP_001141194.1
rat (Rattus norvegicus)	Ubxn11¹	--	UBX domain protein 11	81.92(n) 79.59(a)	192207 NM_138853.2 NP_620208.1
mouse (Mus musculus)	Ubxn11^{1 , 5}	4 (66.50 cM)⁵	UBX domain protein 11^{1, 5}	82.92(n)¹ 81.2(a)¹	67586¹ NM_026257.2¹ NP_080533.1¹ AA921481⁵ AI836226⁵ (see all 14)
chicken (Gallus gallus)	UBXD5¹	--	UBX domain containing 5	57.23(n) 46.99(a)	419546 XM_417696.2 XP_417696.2

About this table Species with no ortholog for UBXN11

ENSEMBL Gene Tree for UBXN11 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

UniProtKB/Swiss-Prot: UBX11_HUMAN, Q5T124

Polymorphism: The number of repeats is polymorphic and varies from 1 to 4

SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs1134580^1,2	C	26608883(-)	`CCCGGC/TCCCGG`	6	G	syn¹ ref¹		0	--	--	--	--
rs1134581^1,2	--	26608879(-)	`GTCCCA/GGCCCC`	6	S G	mis¹ ref¹		0	--	--	--	--
rs1134582^1,2	F	26608877(-)	`CCCGGC/TCCCAG`	6	G	ref¹ syn¹ ese³		1		MN	184
rs1134583^1,2	F	26608873(-)	`GCCCCA/TGTCCC`	6	S C	ref¹ mis¹		1		MN	184
rs1134584^1,2	C,	26608828(-)	`CCGGCT/CCCAGT`	6	/P /S	ref¹ mis¹		4		MN NA	190
rs2276712^1,2	C,F,A,H,	26627478(+)	`TCTTCT/CGAGCC`	5	/S	ref¹ syn¹ int¹ trp³		11		EA NS WA NA	1978
rs3732416^1,2	C,F,A,H,	26620489(-)	`TCTCCG/ACGGTC`	3	--	int¹		14		EA NS NA WA	1794
rs3795682^1,2	C	26633153(-)	`GCACGG/TGTCCT`	3	--	ut5¹ ese³		4		NS EA	418
rs3795683^1,2	C,F,A,H,	26632831(-)	`CCAGAT/GCTCTG`	3	--	int¹		13		EA NA NS WA	1992
rs3795684^1,2	C,F,A,H,	26632781(-)	`AGAATA/GTTGTG`	3	--	int¹		25		NA NS EA WA	1584

About this table

HapMap Linkage Disequilibrium images for UBXN11 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for UBXN11: --

QIAGEN SeqTarget long-range PCR primers for resequencing UBXN11

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

UBXN11 for disorders About GeneDecksing

OMIM: 609151

1 Novoseek disease relationship for UBXN11 gene

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
osteoporosis	29.4	1	15607319 (1)

About this table

Export disorders and mutations for UBXN11 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/34 PubMed articles for UBXN11 gene, integrated from 7 sources (see all 34):
(articles sorted by number of sources associating them with UBXN11)

Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. (PubMed id 11940653)^{1, 2, 3} Katoh H.... Negishi M. (2002)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes. (PubMed id 14583468)^{1, 2} Maccalli C.... Robbins P.F. (2003)
Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1. (PubMed id 18974390)¹ Maccalli C....Belardelli F. (2008)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
Socius, a novel binding partner of Galpha12/13, promotes the Galpha12-induced RhoA activation. (PubMed id 16202387)¹ Tateiwa K.... Negishi M. (2005)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)¹ Rual J.F....Vidal M. (2005)
Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)² Wan D....Gu J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 91544	HGNC: 30600	AceView: SOC	Ensembl:ENSG00000158062	euGenes: HUgn91544
ECgene: UBXN11	H-InvDB: UBXN11

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for UBXN11 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for UBXN11 gene:
Search GeneIP for patents involving UBXN11

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for UBXN11		Antibodies for UBXN11
	Super-pooled esiRNAs for UBXN11		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for UBXN11		Browse microRNA Mimics at Sigma-Aldrich
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
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	Antibodies		Cell Culture Products
	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UBXN11
	SeqTarget long-range PCR primers for resequencing UBXN11
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for UBXN11
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UBXN11

	GenScript Custom Purified and Recombinant Proteins Services for UBXN11		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for UBXN11
	GenScript Custom Assay Services for UBXN11		GenScript Custom Superior Antibodies Services for UBXN11
	GenScript Custom overexpressing Cell Line Services for UBXN11		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Search Regulatory tfbs for UBXN11
	Search Chromatin IP Primers for UBXN11
	RT² qPCR Primer Assay for UBXN11
	Search GNC Networks for UBXN11
	Search for Assays for microRNAs that regulate UBXN11
	SABiosciences Custom PCR Arrays for UBXN11

Search Tocris compounds for UBXN11

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Proteins for UBXN11

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

Browse ELISAs and CLIAs at Uscn

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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GIFtS Group

The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

UBXN11 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

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Export list of displayed genes

UBXN11 Gene

protein-coding GIFtS: 44

Aliases &
Descriptions
for UBXN11 gene

Summaries
for UBXN11 gene

Genomic Views
for UBXN11 gene

Proteins
for UBXN11 gene

Protein Domains/
Families
for UBXN11 gene

Gene Function
for UBXN11 gene

Pathways & Interactions
for UBXN11 gene

Drugs & Compounds
for UBXN11 gene

Transcripts
for UBXN11 gene

Expression
for UBXN11 gene

Orthologs
for UBXN11 gene

Paralogs
for UBXN11 gene

Genomic Variants
for UBXN11 gene

Disorders & Mutations
for UBXN11 gene

Medical News
for UBXN11 gene

Publications
for UBXN11 gene

External Searches for UBXN11 gene

Genome Databases showing UBXN11 gene

Other Databases showing UBXN11 gene

Specialized Databases showing UBXN11 gene

Intellectual Property
for UBXN11 gene

Products
for UBXN11 gene

View Random Gene

Advanced Search

Export list of displayed genes

UBXN11 Gene

protein-coding GIFtS: 44

Aliases & Descriptionsfor UBXN11 gene

Summariesfor UBXN11 gene

Genomic Viewsfor UBXN11 gene

Proteinsfor UBXN11 gene

Protein Domains/Familiesfor UBXN11 gene

Gene Functionfor UBXN11 gene

Pathways & Interactionsfor UBXN11 gene

Drugs & Compoundsfor UBXN11 gene

Transcriptsfor UBXN11 gene

Expression for UBXN11 gene

Orthologsfor UBXN11 gene

Paralogsfor UBXN11 gene

Genomic Variantsfor UBXN11 gene

Disorders & Mutationsfor UBXN11 gene

Medical Newsfor UBXN11 gene

Publicationsfor UBXN11 gene

External Searches for UBXN11 gene

Genome Databases showing UBXN11 gene

Other Databases showing UBXN11 gene

Specialized Databases showing UBXN11 gene

Intellectual Propertyfor UBXN11 gene

Productsfor UBXN11 gene

View Random Gene

Aliases &
Descriptions
for UBXN11 gene

Summaries
for UBXN11 gene

Genomic Views
for UBXN11 gene

Proteins
for UBXN11 gene

Protein Domains/
Families
for UBXN11 gene

Gene Function
for UBXN11 gene

Pathways & Interactions
for UBXN11 gene

Drugs & Compounds
for UBXN11 gene

Transcripts
for UBXN11 gene

Expression
for UBXN11 gene

Orthologs
for UBXN11 gene

Paralogs
for UBXN11 gene

Genomic Variants
for UBXN11 gene

Disorders & Mutations
for UBXN11 gene

Medical News
for UBXN11 gene

Publications
for UBXN11 gene

Intellectual Property
for UBXN11 gene

Products
for UBXN11 gene