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UTP6 Gene

protein-coding   GIFtS: 52

GC17M026401
UTP6, small subunit (SSU) processome component, homolog (yeast)
(Previous name: chromosome 17 open reading frame 40 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C17orf40)
Products    

Aliases &
Descriptions
for UTP6 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
UTP6, small subunit (SSU) processome component, homolog (yeast)1 2     chromosome 17 open reading frame 401
HCA661 2 3     U3 small nucleolar RNA-associated protein 6 homolog2
Hepatocellular carcinoma-associated antigen 662 3     hepatocellular carcinoma associated antigen 662
Multiple hat domains protein2 3     MHAT3
C17orf402 3     

External Ids:    HGNC: 182791   Entrez Gene: 558132   Ensembl: ENSG000001086517   UniProtKB: Q9NYH93   

Export aliases for UTP6 gene to outside databases

Previous GC identifers: GC17M027216 GC17M030187


Summaries
for UTP6 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9
Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

Gene Wiki entry for UTP6

Genomic Views
for UTP6 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UTP6 gene promoter:
         NF-1   c-Myb   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for UTP6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

UTP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UTP6 gene location

GeneLoc gene densities for chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M026401:  view genomic region     (about GC identifiers)

Start:
 26,400,510 bp from pter
End:
 26,439,036 bp from pter
Size:
 38,527 bases
Orientation:
 minus strand

1 alternative location:
Chr17- 30,187,923-30,228,731     
RefSeq DNA sequence:
NC_000017.10  NT_010799.15  

Proteins
for UTP6 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9 (See protein sequence)
Recommended Name: U3 small nucleolar RNA-associated protein 6 homolog  
Size: 597 amino acids; 70194 Da
Subcellular location: Nucleus, nucleolus
Secondary accessions: Q8IX96 Q96BL2 Q9NQ91

Explore the universe of human proteins at neXtProt for UTP6: NX_Q9NYH9 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_060898.2  

    ENSEMBL proteins: 
    ENSP00000261708 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: UTP6
    GenScript Custom Purified and Recombinant Proteins Services for UTP6 
    Novus Biologicals Protein for UTP6
    Novus Biologicals Lysates for UTP6
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular IEA--
    GO:0005634 nucleus IEA--
    GO:0005730 nucleolus IEA--
    About this table

    UTP6 for ontologies           About GeneDecksing



    Antibodies for UTP6: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for UTP6
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for UTP6 
    Novus Biologicals Antibodies for UTP6
    Epitomics antibodies for UTP6

    Assays for UTP6: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for UTP6 
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn 

    Protein Domains/
    Families
    for UTP6 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    UTP6 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011990 TPR-like_helical
     IPR003107 HAT
     IPR013949 U3_snoRNA_assoc-6

    Graphical View of Domain Structure for InterPro Entry Q9NYH9

    ProtoNet protein and cluster: Q9NYH9

    2 Blocks protein families:
    IPB003107 RNA-processing protein
    IPB013949 U3 small nucleolar RNA-associated protein 6


    UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9
    Similarity: Belongs to the UTP6 family
    Similarity: Contains 5 HAT repeats


    Gene Function
    for UTP6 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9
    Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for UTP6
    Sigma-Aldrich shRNA for UTP6
    OriGene 29mer shRNA kits in GFP-retroviral vector: UTP6
    OriGene shRNA RFP: UTP6
    OriGene basic RS shRNA: UTP6
    OriGene siRNA: UTP6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UTP6 
    miRNA:Sigma-Aldrich microRNA Mimics for UTP6
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UTP6 
    Search SABiosciences for Assays for microRNAs that regulate UTP6

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: UTP6
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: UTP6
    OriGene untagged cDNA clones in CMV expression vector: UTP6
    OriGene 3'-UTR clone: UTP6 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: UTP6 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for UTP6 

    1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515 protein binding IEA--
    About this table

    UTP6 for ontologies           About GeneDecksing


    Pathways & Interactions
    for UTP6 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for UTP6 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UTP6

    3 Interacting proteins for UTP6 (Q9NYH92) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C19orf50Q9BQD32MINT-67466
    CCDC85BQ158342MINT-68353
    RHOXF2Q9BQY42MINT-68193
    About this table

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364 rRNA processing IEA--
    GO:0006396 RNA processing IEA--
    About this table

    UTP6 for ontologies           About GeneDecksing



    Drugs & Compounds
    for UTP6 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UTP6


    Transcripts
    for UTP6 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for UTP6
    Sigma-Aldrich shRNA for UTP6
    OriGene 29mer shRNA kits in GFP-retroviral vector: UTP6
    OriGene shRNA RFP: UTP6
    OriGene basic RS shRNA: UTP6
    OriGene siRNA: UTP6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UTP6 
    miRNA: Sigma-Aldrich microRNA Mimics for UTP6
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UTP6 
    Search SABiosciences for Assays for microRNAs that regulate UTP6
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: UTP6
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: UTP6
    OriGene untagged cDNA clones in CMV expression vector: UTP6
    OriGene 3'-UTR Clone: UTP6 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: UTP6 
    Primers: OriGene genome-wide validated SYBR primer pairs: UTP6
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for UTP6: PPH14499A

    REFSEQ mRNAs for UTP6 gene: 

    NM_018428.2  

    Additional cDNA sequence: 

    AF116631.1 AF244135.1 AF334386.1 AJ272197.1 AK057202.1 AK126564.1 AK225448.1 AK299806.1 
    AK315929.1 BC015454.1 BC035325.1 CR607732.1 CR625726.1 

    13 DOTS entries:

    DT.207560  DT.101981307  DT.70103540  DT.91746371  DT.100824134  DT.100824141  DT.120953784  DT.97817416 
    DT.120953780  DT.91942184  DT.95140773  DT.99985401  DT.100841360 

    24/138 AceView cDNA sequences (see all 138):

    BM905762 BM478186 BC035325 BC015454 AI949382 BE675092 AL535002 AW196869 
    AI784001 AK057202 BM829542 AA100219 AW613268 CD721821 BE876142 F24299 
    AI805121 BM550227 CR625726 NM_018428 CR607732 AI862739 AL565738 BQ938611 

    highest scoring ESTs for UTP6:

    AF244135 AF334386 AI628547 AI949382 AK057202 AL535002 BC015454 BC035325 BE074944 BE095240 

    Unigene Cluster for UTP6:

    UTP6, small subunit (SSU) processome component, homolog (yeast)
    Hs.589862  [show with all ESTs]
    Unigene Representative Sequence: AK126564


    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for UTP6 (see all 7)

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16a · 16b ^ 17 ^ 18 ^
    SP1:                                                  -                 -                                               -     -                 -               
    SP2:                                                                                                                    -     -                 -               
    SP3:                                      -     -     -     -           -                                                                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                            -               

    ExUns: 19a · 19b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            

    About this scheme

    ECgene alternative splicing isoforms for UTP6
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000490218 ENST00000261708(uc002hgr.2 uc010cst.2 uc010wbw.1)
    ENST00000484661 ENST00000477128(uc002hgq.2) ENST00000477860

    Expression
    for UTP6 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    UTP6 expression in normal and diseased human tissues

    1  / 2  / 3

    5 probe-sets matching UTP6 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    44861_at2, 3 U95-B 1 1.00 1.00 0.88 1.27 AI949382 0.80 1.00 0.91 1
    50166_at2, 3 U95-B 1 1.00 1.00 0.92 1.24 AI628547 0.80 1.00 0.91 1
    42285_at2 U95-B 1 0.38 1.00 0.76 0.50 -- -- -- -- --
    218715_at2, 3 U133-A 1 0.73 1.00 -- -- NM_018428 0.60 1.00 0.82 1
    218715_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
    About this table

    UTP6 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    UTP6 gene expression
    UTP6 gene electronic northern expression
    UTP6 gene sage expression
    About these images

    CGAP SAGE TAG: CTATGCATCA

    SOURCE GeneReport for Unigene cluster: Hs.589862
    Primers: OriGene genome-wide validated SYBR primer pairs: UTP6
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for UTP6: PPH14499A
        SABiosciences Custom PCR Arrays for UTP6 


    Orthologs
    for UTP6 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for UTP6 gene from 5/14 species (see all 14)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 UTP61   -- UTP6, small subunit (SSU) processome component, homolog more 89.34(n)
    89.61(a)    		 480616  XM_848784.1  XP_853877.1 
    chimpanzee
    (Pan troglodytes)    		 UTP61   -- UTP6, small subunit (SSU) processome component, homolog more 99.42(n)
    99.23(a)    		 454568  XM_511397.2  XP_511397.2 
    cow
    (Bos taurus)    		 UTP61   -- UTP6, small subunit (SSU) processome component, homolog more 81.57(n)
    74.87(a)    		 614984  XM_867469.2  XP_872562.1 
    rat
    (Rattus norvegicus)    		 Utp61   -- UTP6, small subunit (SSU) processome component, homolog more 83.16(n)
    82.15(a)    		 360574  XM_340853.2  XP_340854.1 
    mouse
    (Mus musculus)    		 Utp61 , 5 11 (47.29 cM)5
    		 UTP6, small subunit (SSU) processome component, homolog more1, 5 85.35(n)1
    86.24(a)1    		 2169871  NM_144826.31  NP_659075.11 
     AF3343875  AI4660345  (see all 18)
    About this table        Species with no ortholog for UTP6

    ENSEMBL Gene Tree for UTP6 (if available)

    Paralogs
    for UTP6 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    		  --

    Genomic Variants
    for UTP6 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/355 NCBI SNPs in UTP6 are shown (see all 355)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 17 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs7397991,2
    		C,F30189950(+) CTTGAC/TCTGGG 1 -- ng318Minor allele frequency- T:0.00NA MN NS EA 854
    rs7398001,2
    		C,F,O,A,H,30190083(+) CAAACA/TGAgca 1 -- ng3119Minor allele frequency- T:0.20MN NS EA NA WA 1028
    rs8862231,2
    		C,F,A,30229877(+) GCCTTG/TCATTT 1 -- ng512Minor allele frequency- T:0.16NA EA 160
    rs8862241,2
    		C,F,30229902(+) ACATTT/CTACCC 1 -- ng519Minor allele frequency- C:0.11NS EA NA WA 678
    rs10169951,2
    		C,F,30205130(+) AAACAC/TATATA 1 -- int17Minor allele frequency- T:0.27MN NS EA NA WA 720
    rs10346261,2
    		C,F,O,30219500(+) ATTTTC/GTACCT 1 -- int122Minor allele frequency- G:0.14NS EA NA WA 2764
    rs10346271,2
    		C,F,O,30219569(+) CACACG/ATAAAA 1 -- int17Minor allele frequency- A:0.13NS EA NA 560
    rs14731131,2
    		--30201136(+) TAAGTA/GAGTAA 1 -- int10--------
    rs15577321,2
    		C,F,30227718(+) TTTTTT/AAAAAA 1 -- int12Minor allele frequency- A:0.12NA WA 122
    rs19781151,2
    		C,F,A,30220776(+) aaaaGA/CAGCAG 1 -- int1 trp31Minor allele frequency- C:0.18NA 72
    About this table

    HapMap Linkage Disequilibrium images for UTP6 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for UTP6
         1 CNV: 4030

    QIAGEN SeqTarget long-range PCR primers for resequencing UTP6 

    Disorders & Mutations
    for UTP6 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Medical News
    for UTP6 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for UTP6 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/14 PubMed articles for UTP6 gene, integrated from 7 sources (see all 14):
    (articles sorted by number of sources associating them with UTP6)
    1. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. (PubMed id 10843809)1, 2, 3 Jenne D.E.... Thiel G. (2000)
    2. Evidence by expression analysis of candidate genes fo r congenital heart defects in the NF1 microdeletion interval. (PubMed id 16138909)1, 3 Venturin M....Riva P. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    5. Large scale identification of human hepatocellular carcinoma- associated antigens by autoantibodies. (PubMed id 12097419)1, 2 Wang Y....Chen W.-F. (2002)
    6. Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients. (PubMed id 17380155)1, 7 Piddubnyak V....Poyet J.L. (2007)
    7. Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus. (PubMed id 19299467)1 Fant X....Merdes A. (2009)
    8. Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. (PubMed id 17632510)1 Douglas J.... Rahman N. (2007)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. Nucleolar proteome dynamics. (PubMed id 15635413)1 Andersen J.S....Mann M. (2005)

    External Searches for UTP6 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing UTP6 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55813 HGNC: 18279 AceView: HCA66 Ensembl:ENSG00000108651 euGenes: HUgn55813
    ECgene: UTP6 H-InvDB: UTP6

    Other Databases showing UTP6 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing UTP6 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for UTP6 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for UTP6 gene:
    Search GeneIP for patents involving UTP6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for UTP6 gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for UTP6 Antibodies for UTP6
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     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of UTP6
     SeqTarget long-range PCR primers for resequencing UTP6
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of UTP6
     GenScript Custom Purified and Recombinant Proteins Services for UTP6 GenScript cDNA clones with any tag delivered in your preferred vector for UTP6
     GenScript Custom Assay Services for UTP6 GenScript Custom Superior Antibodies Services for UTP6
     GenScript Custom overexpressing Cell Line Services for UTP6 CloneReady with Over 120,000 Genes
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     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in UTP6 promoter
     Search Chromatin IP Primers for UTP6
     RT2 qPCR Primer Assay for UTP6
     Search GNC Networks for UTP6
     Search for Assays for microRNAs that regulate UTP6
     SABiosciences Custom PCR Arrays for UTP6
     Search Tocris compounds for UTP6
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for UTP6
     Proteins for UTP6
     Lysates for UTP6
     Antibodies for UTP6
     Browse ProSpec Recombinant Proteins

     Browse ELISAs and CLIAs at Uscn
           

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