Aliases &
Descriptions
for WDR81 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| WD repeat domain 811 2 | | OTTHUMP000002046902 | | FLJ338171 2 | | WD repeat-containing protein 812 | | OTTHUMP000002089732 | | OTTHUMP000002071232 | | FLJ237762 | | OTTHUMP000002089742 |
Export aliases for WDR81 gene to outside databases |
Summaries
for WDR81 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for WDR81 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WDR81 gene promoter:
CUTL1 p53 E4BP4 Arnt SREBP-1c SREBP-1a SREBP-1b MZF-1 C/EBPalpha Bach2
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR81
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for WDR81  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3WDR81 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P001567: view genomic region
(about GC identifiers)
Start:
|
1,519,509 bp from pter |
End:
|
1,541,250 bp from pter |
Size:
|
21,742 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr17+ 1,619,817-1,641,888 |
RefSeq DNA sequence:- NC_000017.10 NT_010718.16
|
Proteins
for WDR81 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: WDR81_HUMAN, Q562E7 (See
protein sequence)Recommended Name: WD repeat-containing protein 81 Size: 890 amino acids; 95676 Da
Sequence caution: Sequence=CAD39042.1; Type=Erroneous initiation;
Secondary accessions: Q24JP6 Q8N277 Q8N3F3Alternative splicing: 2 isoforms: Q562E7-1 Q562E7-2 Explore the universe of human proteins at neXtProt for WDR81: NX_Q562E7
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (4 alternative transcripts):
NP_001157145.1 NP_001157281.1 NP_001157283.1 NP_689561.2
ENSEMBL proteins: ENSP00000395198 ENSP00000395226 ENSP00000312074 ENSP00000391074 ENSP00000386609 ENSP00000401560 ENSP00000346710 ENSP00000407845
Human Recombinant Proteins
Antibodies for WDR81:
Assays for WDR81: |
Protein
Domains/
Families
for WDR81 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WDR81 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q562E7ProtoNet protein and cluster: Q562E7 UniProtKB/Swiss-Prot: WDR81_HUMAN, Q562E7Similarity: Contains 5 WD repeats |
Gene Function
for WDR81 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for WDR81 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for WDR81
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR81
|
Drugs & Compounds
for WDR81 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for WDR81
|
Transcripts
for WDR81 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for WDR81 gene (4 alternative transcripts): NM_001163673.1 NM_001163809.1 NM_001163811.1 NM_152348.3 Additional cDNA sequence: AK074356.1 AK091136.1 AK122972.1 AK123896.1 AK127946.1 AK298567.1 AK300986.1 AL834379.1 BC092513.1 BC114519.1 BC114568.1 CR621271.1 10 DOTS entries: DT.313658 DT.97819703 DT.86843670 DT.100747888 DT.99963254 DT.40289653 DT.91751328 DT.120948577 DT.102826202 DT.120948628 24/101 AceView cDNA sequences (see all 101): AK123896 BQ937348 CA440653 BM983030 F01373 BP354361 AA299430 F08317 CR621271 AL834379 CD673112 Z41585 AA826119 BE208640 BQ016501 BF348340 H53510 AW172812 BM477178 AW384537 CD672821 BX334970 BU501618 BM802575
 highest scoring ESTs for WDR81:AA150502 AA299430 AA826119 AA977554 AI084119 AI122733 AI168277 AI435458 AI635616 AI679646 Unigene Cluster for WDR81: WD repeat domain 81 Hs.234572 [show with all ESTs]Unigene Representative Sequence: NM_001163809
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for WDR81 (see all 9)
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for WDR81
14 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000418841 ENST00000474958 ENST00000464528 ENST00000455636 ENST00000492901
ENST00000495411 ENST00000309182(uc002fth.2 uc010vqp.1) ENST00000468539
ENST00000437219 ENST00000409644(uc002ftj.2) ENST00000446363 ENST00000479966
ENST00000354680 ENST00000419248(uc002fti.2 uc010vqq.1)
|
Expression
for WDR81 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| WDR81 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching WDR81 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 56293_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
AA150502 |
1.00 |
1.00 |
1.00 |
1 |
| 226738_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
BE675297 |
0.80 |
1.00 |
0.91 |
1 |
| 226738_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
WDR81 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CGTTGTCTGC
SOURCE GeneReport for Unigene cluster: Hs.234572
SABiosciences Custom PCR Arrays for WDR81
|
Orthologs
for WDR81 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for WDR81 gene from 5/8 species (see all 8)
About this table Species with no ortholog for WDR81
ENSEMBL Gene Tree for WDR81 (if available) |
Paralogs
for WDR81 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for WDR81 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 17 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for WDR81 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for WDR81
5 CNVs: 49826 32148 30021 49827 35433 | | QIAGEN SeqTarget long-range PCR primers for resequencing WDR81 |
|
Disorders & Mutations
for WDR81 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for WDR81 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for WDR81 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for WDR81 gene integrated from 7 sources:
(articles sorted by number of sources associating them with WDR81)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. (PubMed id 20705733)1 O'Seaghdha C.M....KAPttgen A. (2010 Nov 1)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for WDR81 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WDR81 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR81 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR81 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for WDR81 gene:
Search GeneIP for patents involving WDR81
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR81 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for WDR81 |
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