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WNT8A Gene

protein-coding GIFtS: 51

GC05P132610

wingless-type MMTV integration site family, member 8A
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
wingless-type MMTV integration site family, member 8A¹ ²		OTTHUMP00000223361²
WNT8D¹ ² ³		WNT8d²
Protein Wnt-8d² ³		OTTHUMP00000223458²
protein Wnt-8a²

External Ids:	HGNC: 12788¹	Entrez Gene: 7478²	Ensembl: ENSG00000061492⁷	UniProtKB: Q9H1J5³

Export aliases for WNT8A gene to outside databases

Previous GC identifers: GC05P137294 GC05P138095 GC05P137450 GC05P137495 GC05P137447

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WNT8A:

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins

have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and

patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of

early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A

protein. (provided by RefSeq)

UniProtKB/Swiss-Prot: WNT8A_HUMAN, Q9H1J5

Function: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the

development and differentiation of certain forebrain structures, notably the hippocampus

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the WNT8A gene promoter:
         NF-kappaB1   HNF-4alpha2   NF-kappaB   COUP-TF1   ER-alpha   GATA-1   STAT1alpha   STAT1beta   STAT1   STAT3
         Other transcription factors

Search SABiosciences Chromatin IP Primers for WNT8A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31 Ensembl cytogenetic band: 5q31.2 HGNC cytogenetic band: 5q31

WNT8A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WNT8A gene location

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P132610: view genomic region (about GC identifiers)

Start:	132,610,733 bp from pter
End:	132,618,179 bp from pter
Size:	7,447 bases
Orientation:	plus strand

1 alternative location:

Chr5+ 137,419,581-137,428,054

RefSeq DNA sequence:

NC_000005.9 NT_034772.6

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: WNT8A_HUMAN, Q9H1J5 (See protein sequence)

Recommended Name: Protein Wnt-8a precursor

Size: 351 amino acids; 38849 Da

Subcellular location: Secreted, extracellular space, extracellular matrix

Secondary accessions: Q96S51

Alternative splicing: 2 isoforms: Q9H1J5-1 Q9H1J5-2

Explore the universe of human proteins at neXtProt for WNT8A: NX_Q9H1J5

REFSEQ proteins: NP_490645.1

ENSEMBL proteins:

ENSP00000424809 ENSP00000381739 ENSP00000426653 ENSP00000354726

Human Recombinant Proteins

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4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005578	proteinaceous extracellular matrix	ISS	--
GO:0005615	colocalizes with extracellular space	ISS	--
GO:0005886	plasma membrane	ISS	--

About this table

WNT8A for ontologies About GeneDecksing

Antibodies for WNT8A:

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	Browse antibodies at Epitomics

Assays for WNT8A:

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	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for WNT8A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for WNT8A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

WNT8A for domains About GeneDecksing

4 InterPro domains/families:

IPR005816 Wnt_grthfactor

IPR013301 Wnt8

IPR005817 Wnt_SF

IPR018161 Wnt_grthfactor_CS

Graphical View of Domain Structure for InterPro Entry Q9H1J5

ProtoNet protein and cluster: Q9H1J5

1 Blocks protein family: IPB005816 Secreted growth factor Wnt protein

UniProtKB/Swiss-Prot: WNT8A_HUMAN, Q9H1J5

Similarity: Belongs to the Wnt family

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: WNT8A_HUMAN, Q9H1J5

Function: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the

development and differentiation of certain forebrain structures, notably the hippocampus

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA for WNT8A Sigma-Aldrich shRNA for WNT8A
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): WNT8A OriGene shRNA RFP (see all 2): WNT8A OriGene basic RS shRNA (see all 2): WNT8A OriGene siRNA (see all 2): WNT8A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of WNT8A

miRNA:		Sigma-Aldrich microRNA Mimics for WNT8A Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of WNT8A
		Search SABiosciences for Assays for microRNAs that regulate WNT8A

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: WNT8A OriGene Myc/DDK tagged cDNA clones in CMV expression vector: WNT8A OriGene untagged cDNA clones in CMV expression vector (see all 2): WNT8A Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for WNT8A
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for WNT8A

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001664	G-protein-coupled receptor binding	ISS	--
GO:0004871	signal transducer activity	IEA	--
GO:0005109	frizzled binding	NAS	11408932
GO:0005515	protein binding	--	--

About this table

WNT8A for ontologies About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

WNT8A for pathways About GeneDecksing

2 Millipore Pathways for WNT8A

	Transcription Androgen Receptor nuclear signaling
	Translation Non-genomic (rapid) action of Androgen Receptor

5/11 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for WNT8A (see all 11)

	Wnt/β-catenin Signaling
	Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis
	Human Embryonic Stem Cell Pluripotency
	Glioblastoma Multiforme Signaling
	Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis

5 Kegg Pathways (Kegg details for WNT8A):

	hsa04310 Wnt signaling pathway
	hsa04340 Hedgehog signaling pathway
	hsa04916 Melanogenesis
	hsa05200 Pathways in cancer
	hsa05217 Basal cell carcinoma

SABiosciences Pathway-Focused PCR Arrays including WNT8A: PAHS-043A PAHS-078A

Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for WNT8A

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for WNT8A

5/35 Interacting proteins for WNT8A (ENSP00000354726³) via UniProtKB, MINT, and/or STRING (see all 35)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FZD1	ENSP00000287934³	STRING: ENSP00000287934
FZD2	ENSP00000323901³	STRING: ENSP00000323901
WNT8B	ENSP00000340677³	STRING: ENSP00000340677
CER1	ENSP00000370297³	STRING: ENSP00000370297
FZD10	ENSP00000229030³	STRING: ENSP00000229030

About this table

5/34 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 34):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000902	cell morphogenesis	--	--
GO:0001654	eye development	ISS	--
GO:0001710	mesodermal cell fate commitment	ISS	--
GO:0001756	somitogenesis	ISS	--
GO:0003002	regionalization	--	--

About this table

WNT8A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for WNT8A

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA for WNT8A Sigma-Aldrich shRNA for WNT8A
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): WNT8A OriGene shRNA RFP (see all 2): WNT8A OriGene basic RS shRNA (see all 2): WNT8A OriGene siRNA (see all 2): WNT8A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of WNT8A

miRNA:		Sigma-Aldrich microRNA Mimics for WNT8A Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of WNT8A
		Search SABiosciences for Assays for microRNAs that regulate WNT8A

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: WNT8A OriGene Myc/DDK tagged cDNA clones in CMV expression vector: WNT8A OriGene untagged cDNA clones in CMV expression vector (see all 2): WNT8A Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for WNT8A

Primers:		OriGene genome-wide validated SYBR primer pairs: WNT8A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for WNT8A: PPH02444A

REFSEQ mRNAs for WNT8A gene:

NM_058244.2

Additional cDNA sequence:

AB057725.1 BC144001.1 BC144497.1

1 DOTS entry:

DT.95148953

6 AceView cDNA sequences:

NM_031933 AY009402 AB057725 NM_058244 AW663893 BQ428931

highest scoring ESTs for WNT8A:

AB057725 AY009402 NM_058244 NM_031933 AW663893 BQ428931

Unigene Cluster for WNT8A:

Wingless-type MMTV integration site family, member 8A

Hs.591274

Unigene Representative Sequence: BC144497

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for WNT8A

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7
SP1:
SP2:

About this scheme

ECgene alternative splicing isoforms for WNT8A
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000504809 ENST00000398754(uc003lcd.1) ENST00000506684(uc011cyj.1 uc011cyk.1)

ENST00000361560

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

WNT8A expression in normal and diseased human tissues

¹ / ² / ³

2 probe-sets matching WNT8A gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
224259_at²^{, 3}	U133-B	1	0.36	1.00	--	--	AY009402	0.60	1.00	0.82	1
224259_at²	U133Plus2	1	0.36	1.00	--	--	--	--	--	--	--

About this table
Data from Genenote (Publications) and GNF BioGPS
About these images

WNT8A gene electronic northern expression

About these images

CGAP SAGE TAG: TCCAACCCAG

SOURCE GeneReport for Unigene cluster: Hs.591274

Primers:		OriGene genome-wide validated SYBR primer pairs: WNT8A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for WNT8A: PPH02444A

SABiosciences Expression via Pathway-Focused PCR Arrays including WNT8A: PAHS-043A PAHS-078A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for WNT8A gene from 5/9 species (see all 9)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	WNT8A¹	--	wingless-type MMTV integration site family, member more	89.74(n) 91.74(a)	481525 XM_538646.1 XP_538646.1
chimpanzee (Pan troglodytes)	WNT8A¹	--	wingless-type MMTV integration site family, member more	99.14(n) 99.14(a)	471645 XM_527023.2 XP_527023.2
cow (Bos taurus)	WNT8A¹	--	wingless-type MMTV integration site family, member more	88.79(n) 91.17(a)	540199 XM_592239.2 XP_592239.2
rat (Rattus norvegicus)	Wnt8a¹	--	wingless-type MMTV integration site family, member more	84.53(n) 82.13(a)	291678 XM_226051.4 XP_226051.4
mouse (Mus musculus)	Wnt8a^{1 , 5}	18 (18.69 cM)⁵	wingless-related MMTV integration site 8A^{1, 5}	83.86(n)¹ 81.09(a)¹	20890¹ NM_009290.1¹ NP_033316.1¹ AA139161⁵ BC119212⁵ (see all 7)

About this table Species with no ortholog for WNT8A

ENSEMBL Gene Tree for WNT8A (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for WNT8A gene

WNT3A² WNT1² WNT8B² WNT4² WNT6² WNT3²

WNT8A for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs172607^1,2	--	137422087(+)	`tttttA/Tgtaga`	1	--	int¹		0	--	--	--	--
rs217254^1,2	C,A,H	137427564(+)	`aataaA/Ctaata`	1	--	ng3¹		0	--	--	--	--
rs217255^1,2	C,H,	137427677(+)	`AAAGGG/CAATCA`	1	--	ng3¹		6		NA WA	12
rs217267^1,2	C,A,	137421274(+)	`GAACcA/Gtgcct`	1	--	int¹		5		NA EA WA	214
rs217268^1,2	C	137422329(+)	`gctcaA/Cacctg`	1	--	int¹		3		NA	6
rs217269^1,2	C,H	137422722(+)	`agagtG/Aagagc`	1	--	int¹		5		NA WA	10
rs1017778^1,2	--	137421187(-)	`AAAATG/TACATG`	1	--	int¹		1		MN	184
rs2040862^1,2	C,F,O,	137419989(+)	`TCCAGC/TTTCTG`	1	--	int¹		5		NS EA NA	484
rs3860103^1,2	C,A,H,	137427274(+)	`TGTTGG/CATTTT`	1	--	ng3¹		5		NA EA WA	214
rs3860104^1,2	C,A,H,	137427486(+)	`ctccaG/Acctgg`	1	--	ng3¹		4		EA NA	94

About this table

HapMap Linkage Disequilibrium images for WNT8A (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for WNT8A: --

QIAGEN SeqTarget long-range PCR primers for resequencing WNT8A

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

WNT8A for disorders About GeneDecksing

OMIM: 606360

Human Genome Epidemiology (HuGE) Navigator: WNT8A (2 documents)

Export disorders and mutations for WNT8A gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

6 PubMed articles for WNT8A gene integrated from 7 sources:
(articles sorted by number of sources associating them with WNT8A)

Molecular cloning and characterization of human WNT8A. (PubMed id 11408932)^{1, 2, 3} Saitoh T. and Katoh M. (2001)
Studies with Wnt genes and nonsyndromic cleft lip and palate. (PubMed id 20890934)¹ Menezes R....Vieira A.R. (2010)
Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. (PubMed id 18413325)¹ Chiquet B.T....Hecht J.T. (2008)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Expression and regulation of WNT8A and WNT8B mRNAs in human tumor cell lines: up-regulation of WNT8B mRNA by beta-estradiol in MCF-7 cells, and down-regulation of WNT8A and WNT8B mRNAs by retinoic acid in NT2 cells. (PubMed id 11956596)¹ Saitoh T....Katoh M. (2002)
Wnt family proteins are secreted and associated with the cell surface. (PubMed id 8167409)¹ Smolich B.D....Papkoff J. (1993)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 7478	HGNC: 12788	AceView: WNT8A	Ensembl:ENSG00000061492	euGenes: HUgn7478
ECgene: WNT8A	Kegg: 7478	H-InvDB: WNT8A

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for WNT8A	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for WNT8A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for WNT8A gene:
Search GeneIP for patents involving WNT8A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for WNT8A		Antibodies for WNT8A
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	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
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	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
	feedback

	Antibodies for WNT8A (Wnt-8a)		Cell Culture Products
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of WNT8A
	SeqTarget long-range PCR primers for resequencing WNT8A
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of WNT8A

	GenScript Custom Purified and Recombinant Proteins Services for WNT8A		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for WNT8A
	GenScript Custom Assay Services for WNT8A		GenScript Custom Superior Antibodies Services for WNT8A
	GenScript Custom overexpressing Cell Line Services for WNT8A		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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ELISAs and CLIAs for WNT8A

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

WNT8A gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

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WNT8A Gene

protein-coding GIFtS: 51

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WNT8A Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor WNT8A gene

Summariesfor WNT8A gene

Genomic Viewsfor WNT8A gene

Proteinsfor WNT8A gene

Protein Domains/Familiesfor WNT8A gene

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External Searches for WNT8A gene

Genome Databases showing WNT8A gene

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Specialized Databases showing WNT8A gene

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Aliases &
Descriptions
for WNT8A gene

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for WNT8A gene

Genomic Views
for WNT8A gene

Proteins
for WNT8A gene

Protein Domains/
Families
for WNT8A gene

Gene Function
for WNT8A gene

Pathways & Interactions
for WNT8A gene

Drugs & Compounds
for WNT8A gene

Transcripts
for WNT8A gene

Expression
for WNT8A gene

Orthologs
for WNT8A gene

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for WNT8A gene

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