Aliases &
Descriptions
for ZBTB49 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger and BTB domain containing 491 2 | | MGC1262792 | | Zinc finger protein 5091 2 3 | | MGC1262802 | | FLJ385591 2 | | zinc finger and BTB domain-containing protein 492 | | ZNF5092 3 | | |
Export aliases for ZBTB49 gene to outside databases |
Summaries
for ZBTB49 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZBT49_HUMAN, Q6ZSB9Function: May be involved in transcriptional regulation
|
Genomic Views
for ZBTB49 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZBTB49
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBTB49
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZBTB49  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.2ZBTB49 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P004291: view genomic region
(about GC identifiers)
Start:
|
4,227,608 bp from pter |
End:
|
4,259,207 bp from pter |
Size:
|
31,600 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr4+ 4,291,924-4,323,513 |
RefSeq DNA sequence:- NC_000004.11 NT_006051.18
|
Proteins
for ZBTB49 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZBT49_HUMAN, Q6ZSB9 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 49 Size: 765 amino acids; 85061 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAH16477.1; Type=Erroneous termination; Positions=372; Note=Translated as Glu;
Secondary accessions: Q59FJ4 Q5EBN0 Q8TB80Alternative splicing: 2 isoforms: Q6ZSB9-1 Q6ZSB9-2 Explore the universe of human proteins at neXtProt for ZBTB49: NX_Q6ZSB9
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_660334.3
ENSEMBL proteins: ENSP00000422321 ENSP00000338807 ENSP00000424525 ENSP00000425747 ENSP00000421654 ENSP00000426765 ENSP00000348091
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZBTB49 for ontologies About GeneDecksing
Antibodies for ZBTB49:
Assays for ZBTB49: |
Protein
Domains/
Families
for ZBTB49 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBTB49 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q6ZSB9ProtoNet protein and cluster: Q6ZSB9 2 Blocks protein families: IPB000210 BTB/POZ domain IPB011069 Aspartate carbamoyltransferase
UniProtKB/Swiss-Prot: ZBT49_HUMAN, Q6ZSB9Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 1 BTB (POZ) domainSimilarity: Contains 7 C2H2-type zinc fingers |
Gene Function
for ZBTB49 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZBT49_HUMAN, Q6ZSB9Function: May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZBTB49 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZBTB49 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZBTB49
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBTB49
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0045449 | regulation of transcription |
IEA | -- |
About this table
ZBTB49 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZBTB49 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZBTB49
|
Transcripts
for ZBTB49 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZBTB49 gene: NM_145291.3 Additional cDNA sequence: AB209466.1 AK095878.1 AK127560.1 AK292551.1 AL832751.1 BC016477.1 BC089401.1 BC109087.1 BC109088.1 3 DOTS entries: DT.97838065 DT.410485 DT.100019620 24/43 AceView cDNA sequences (see all 43): AW473523 CA391470 AW236515 BM682010 CA435417 AI968348 AI911852 BG764475 AI376031 BM729079 AI014894 BC016477 AA993690 BF196920 AA448473 AL832751 BF035755 AK127560 BX451847 BF061904 BE551972 NM_145291 BE501704 AA432010 Unigene Cluster for ZBTB49: Zinc finger and BTB domain containing 49 Hs.419997 [show with all ESTs]Unigene Representative Sequence: NM_145291
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB49
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZBTB49
7 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000515012 ENST00000337872(uc003ghu.2 uc010icy.2) ENST00000503703(uc003ghv.2)
ENST00000502918 ENST00000504302 ENST00000511458 ENST00000355834(uc010icz.2)
|
Expression
for ZBTB49 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZBTB49 expression in normal and diseased human tissues
1 / 2 3 probe-sets matching ZBTB49 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 55460_at2
|
U95-B |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
| 229089_at2
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 229089_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZBTB49 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GAGTTAGTGA
SOURCE GeneReport for Unigene cluster: Hs.419997
SABiosciences Custom PCR Arrays for ZBTB49
|
Orthologs
for ZBTB49 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZBTB49 gene from 5/8 species (see all 8)
About this table Species with no ortholog for ZBTB49
ENSEMBL Gene Tree for ZBTB49 (if available) |
Paralogs
for ZBTB49 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZBTB49 gene
- ZBTB32 ZBTB52 HIC12 ZNF2382 HIC22 ZBTB422 GZF12 MYNN2
- ZBTB172
ZBTB49 for paralogs About GeneDecksing
|
Genomic Variants
for ZBTB49 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 4 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZBTB49 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZBTB49
2 CNVs: 31156 3477 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZBTB49 |
|
Disorders & Mutations
for ZBTB49 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZBTB49 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZBTB49 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for ZBTB49 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZBTB49)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. (PubMed id 17053785)2 Wang Y.... Chen Z. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
|
External Searches for ZBTB49 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZBTB49 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZBTB49 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBTB49 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZBTB49 gene:
Search GeneIP for patents involving ZBTB49
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZBTB49 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
 |
 |
| | |
 |  |  |  | |
| |  | Search Tocris compounds for ZBTB49 |
| |  |  |  |  | | | | |
 | | |
|
|
