Aliases &
Descriptions
for ZC3H15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger CCCH-type containing 151 2 | | zinc finger CCCH domain-containing protein 152 | | LEREPO41 2 3 | | HT0102 | | Likely ortholog of mouse immediate early response erythropoietin 42 3 | | MSTP0122 | | DRG family-regulatory protein 12 3 | | DFRP13 |
Export aliases for ZC3H15 gene to outside databasesPrevious GC identifers: GC02P187060 GC02P187350 |
Summaries
for ZC3H15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZC3HF_HUMAN, Q8WU90Function: Protects DRG1 from proteolytic degradation (By similarity)
|
Genomic Views
for ZC3H15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZC3H15
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZC3H15
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZC3H15  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q32.1 Ensembl cytogenetic band: 2q32.1 HGNC cytogenetic band: 2q32.1ZC3H15 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P179210: view genomic region
(about GC identifiers)
Start:
|
179,210,476 bp from pter |
End:
|
179,234,063 bp from pter |
Size:
|
23,588 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr2+ 187,350,883-187,374,090 |
RefSeq DNA sequence:- NC_000002.11 NT_005403.17
|
Proteins
for ZC3H15 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZC3HF_HUMAN, Q8WU90 (See
protein sequence)Recommended Name: Zinc finger CCCH domain-containing protein 15 Size: 426 amino acids; 48602 Da
Subunit: Interacts with DRG1
Subcellular location: Cytoplasm. Nucleus (By similarity)
Sequence caution: Sequence=AAF28981.1; Type=Frameshift; Positions=17; Sequence=AAF67649.1; Type=Frameshift;Positions=392, 407, 422; Sequence=AAL55770.1; Type=Frameshift; Positions=92; Sequence=AAQ13514.1; Type=Frameshift;Positions=404, 424;
Secondary accessions: Q5QTQ4 Q8WZ06 Q9NUZ3 Q9NZ37 Q9P079Explore the universe of human proteins at neXtProt for ZC3H15: NX_Q8WU90
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_060941.2
ENSEMBL proteins: ENSP00000407192 ENSP00000415788 ENSP00000410981 ENSP00000338788
Human Recombinant Proteins
4 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZC3H15 for ontologies About GeneDecksing
Antibodies for ZC3H15:
Assays for ZC3H15: |
Protein
Domains/
Families
for ZC3H15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZC3H15 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8WU90ProtoNet protein and cluster: Q8WU90 1 Blocks protein family: IPB000571 Zn-finger
UniProtKB/Swiss-Prot: ZC3HF_HUMAN, Q8WU90Similarity: Belongs to the ZC3H15/TMA46 familySimilarity: Contains 2 C3H1-type zinc fingers |
Gene Function
for ZC3H15 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZC3HF_HUMAN, Q8WU90Function: Protects DRG1 from proteolytic degradation (By similarity)
3 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZC3H15 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZC3H15 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZC3H15
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZC3H15
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019221 | cytokine-mediated signaling pathway |
IEA | -- |
About this table
ZC3H15 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZC3H15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZC3H15
|
Transcripts
for ZC3H15 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZC3H15 gene: NM_018471.2 Additional cDNA sequence: AF109366.1 AF119892.1 AF147724.1 AF161421.1 AF220184.1 AF289586.1 AF462448.1 AK001901.1 AK297658.1 AK298615.1 AL049948.1 BC012336.1 BC021102.1 CR601058.1 CR601257.1 CR618848.1 CR622467.1 14 DOTS entries: DT.416259 DT.99986229 DT.100813839 DT.121034625 DT.91758211 DT.100813846 DT.75185742 DT.312650 DT.100813844 DT.416262 DT.121034664 DT.95133135 DT.100655472 DT.95154249 24/371 AceView cDNA sequences (see all 371): AI346688 AA550976 BP371687 BE207196 AU139078 BP343217 CA389493 AA321996 CR601058 AL041992 BQ776270 AL711370 AK001901 BM693462 BM756137 AI828594 BM802250 BM843205 BM312165 CB853429 BM471678 AI383020 BM788314 BQ433362
 highest scoring ESTs for ZC3H15:AA054718 AA056989 AA057864 AA102512 AA205953 AA448883 AA558954 AA670250 AF147724 AF161421 Unigene Cluster for ZC3H15: Zinc finger CCCH-type containing 15 Hs.725998 [show with all ESTs]Unigene Representative Sequence: AK298615
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H15
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZC3H15
9 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496289 ENST00000437396 ENST00000468120 ENST00000498757 ENST00000445547
ENST00000421536 ENST00000481101 ENST00000337859(uc002upo.2) ENST00000477672
|
Expression
for ZC3H15 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZC3H15 expression in normal and diseased human tissues
1 / 2 / 3 5 probe-sets matching ZC3H15 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 35750_at2, 3
|
U95-A |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
AL049948 |
0.80 |
1.00 |
0.91 |
1 |
| 201593_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
AV716798 |
0.60 |
1.00 |
0.82 |
1 |
| 201595_s_at2, 3
|
U133-A |
1 |
0.91 |
1.00 |
-- |
-- |
NM_018471 |
0.60 |
1.00 |
0.82 |
1 |
| 201593_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 201595_s_at2
|
U133Plus2 |
1 |
0.91 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZC3H15 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AGCACTGTAC
SOURCE GeneReport for Unigene cluster: Hs.725998
SABiosciences Custom PCR Arrays for ZC3H15
|
Orthologs
for ZC3H15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZC3H15 gene from 5/24 species (see all 24)
About this table Species with no ortholog for ZC3H15
ENSEMBL Gene Tree for ZC3H15 (if available) |
Paralogs
for ZC3H15 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for ZC3H15 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 2 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZC3H15 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZC3H15
1 CNV: 3403 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZC3H15 |
|
Disorders & Mutations
for ZC3H15 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZC3H15 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZC3H15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/14 PubMed articles for ZC3H15 gene, integrated from 7 sources (see all 14):
(articles sorted by number of sources associating them with ZC3H15)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Subtraction cloning and initial characterization of novel epo-immediate response genes. (PubMed id 10880228)1, 3 Gregory R.C....Wojchowski D.M. (2000)
- Inhibition of X4-tropic HIV type 1 replication by kno ckdown of the cellular protein LEREPO4. (PubMed id 20925576)1 Capalbo G....Scheuring U.J. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Identification of DRG family regulatory proteins (DFRPs): specific regulation of DRG1 and DRG2. (PubMed id 15676025)2 Ishikawa K.... Inoue J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for ZC3H15 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZC3H15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZC3H15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZC3H15 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZC3H15 gene:
Search GeneIP for patents involving ZC3H15
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZC3H15 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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