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ZFR Gene

protein-coding   GIFtS: 49

GC05M032390
zinc finger RNA binding protein
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
zinc finger RNA binding protein1 2
ZFR11 2
M-phase phosphoprotein homolog2 3
hZFR2 3
zinc finger RNA-binding protein2
FLJ413122

External Ids:    HGNC: 172771   Entrez Gene: 516632   Ensembl: ENSG000000560977   UniProtKB: Q96KR13   

Export aliases for ZFR gene to outside databases

Previous GC identifers: GC05M032141 GC05M032800 GC05M032354 GC05M032399


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZFR_HUMAN, Q96KR1
Function: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic
shuttling of STAU2. Binds to DNA and RNA (By similarity)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZFR gene promoter:
         YY1   p300   AhR   Arnt   POU2F1   HNF-4alpha2   COUP-TF1   Pax-5   ER-alpha   ATF-2   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ZFR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZFR 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13.3   Ensembl cytogenetic band:  5p13.3   HGNC cytogenetic band: 5p15.2

ZFR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZFR gene location

GeneLoc gene densities for chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M032390:  view genomic region     (about GC identifiers)

Start:
32,321,365 bp from pter
End:
32,444,867 bp from pter
Size:
123,503 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000005.9  NT_006576.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ZFR_HUMAN, Q96KR1 (See protein sequence)
Recommended Name: Zinc finger RNA-binding protein  
Size: 1074 amino acids; 117012 Da
Subunit: Found in a cytoplasmic RNP complex with STAU2. Interacts with STAU2. Does not interact with STAU1 (By
similarity)
Subcellular location: Nucleus (By similarity). Cytoplasm (By similarity). Cytoplasmic granule (By similarity).
Chromosome (By similarity). Note=Associated with chromosome foci in meiotic cells. Localizes in somatodendritic
compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules (By similarity)
Sequence caution: Sequence=AAD40385.1; Type=Erroneous initiation; Sequence=AAH30540.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAI07418.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAB15147.1; Type=Erroneous initiation;
Sequence=CAC40818.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAC40818.1;
Type=Frameshift; Positions=1057;
Secondary accessions: B2RNR5 Q05C08 Q3B7X5 Q6P5A3 Q86UA0 Q9H6V4 Q9NTI1 Q9Y687

Explore the universe of human proteins at neXtProt for ZFR: NX_Q96KR1 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_057191.2  

    ENSEMBL proteins: 
    ENSP00000422300 ENSP00000393243 ENSP00000371560 ENSP00000265069 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for ZFR 
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular IEA--
    GO:0005634 nucleus IDA18029348
    GO:0005694 chromosome IEA--
    GO:0005730NOT nucleolus IDA18029348
    GO:0005737 cytoplasm IEA--
    About this table

    ZFR for ontologies           About GeneDecksing



    Antibodies for ZFR: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ZFR
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for ZFR 
    Browse antibodies at Epitomics

    Assays for ZFR: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZFR 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ZFR 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ZFR for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR003604 Znf_U1
     IPR006561 DZF
     IPR015880 Znf_C2H2-like
     IPR007087 Znf_C2H2
     IPR022755 Znf_C2H2_jaz

    Graphical View of Domain Structure for InterPro Entry Q96KR1

    ProtoNet protein and cluster: Q96KR1

    1 Blocks protein family: IPB003604 Zn-finger

    UniProtKB/Swiss-Prot: ZFR_HUMAN, Q96KR1
    Similarity: Contains 1 DZF domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: ZFR_HUMAN, Q96KR1
    Function: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic
    shuttling of STAU2. Binds to DNA and RNA (By similarity)

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for ZFR
    Sigma-Aldrich shRNA for ZFR
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZFR
    OriGene shRNA RFP (see all 2): ZFR
    OriGene basic RS shRNA (see all 2): ZFR
    OriGene siRNA (see all 2): ZFR
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZFR 
    miRNA:Sigma-Aldrich microRNA Mimics for ZFR
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZFR 
    5 SABiosciences Assays for microRNAs that regulate ZFR:
    hsa-miR-141 hsa-miR-548a-3p hsa-miR-200a hsa-miR-548e hsa-miR-512-3p

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: ZFR
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZFR
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ZFR
    OriGene 3'-UTR clone: ZFR 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ZFR 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for ZFR 

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676 nucleic acid binding ----
    GO:0003677 DNA binding IEA--
    GO:0003723 RNA binding IEA--
    GO:0008270 zinc ion binding IEA--
    About this table

    ZFR for ontologies           About GeneDecksing

    Animal Models: 3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Zfr):

    embryogenesisgrowth/sizelethality-prenatal/perinatal

    ZFR for phenotypes           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for ZFR 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZFR

    1 Interacting protein for ZFR (Q96KR12) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    --P310162MINT-7972920
    About this table

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275 multicellular organismal development IEA--
    About this table

    ZFR for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    ZFR for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZFR
    1 Novoseek chemical compound relationship for ZFR gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 46.8 6 16890764 (1), 20211283 (1), 1717260 (1), 18519039 (1) (see all 6)
    About this table



    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for ZFR
    Sigma-Aldrich shRNA for ZFR
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZFR
    OriGene shRNA RFP (see all 2): ZFR
    OriGene basic RS shRNA (see all 2): ZFR
    OriGene siRNA (see all 2): ZFR
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZFR 
    miRNA: Sigma-Aldrich microRNA Mimics for ZFR
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZFR 
    5 SABiosciences Assays for microRNAs that regulate ZFR:
    hsa-miR-141 hsa-miR-548a-3p hsa-miR-200a hsa-miR-548e hsa-miR-512-3p
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: ZFR
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZFR
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ZFR
    OriGene 3'-UTR Clone: ZFR 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ZFR 
    Primers: OriGene genome-wide validated SYBR primer pairs: ZFR
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ZFR: PPH13591A

    REFSEQ mRNAs for ZFR gene: 

    NM_016107.3  

    Additional cDNA sequence: 

    AF100742.1 AJ314790.1 AK025481.1 AK055938.1 AK123306.1 AK292214.1 AK295297.1 AK307808.1 
    AK309638.1 AL137258.1 BC017879.1 BC030540.1 BC038973.1 BC051893.1 BC062986.1 BC107417.1 
    BC137084.1 BC137085.1 U00951.1 U00960.1 

    9 DOTS entries:

    DT.447844  DT.91759257  DT.40111860  DT.95123261  DT.101966650  DT.120816384  DT.120816377  DT.112477 
    DT.121366606 

    24/308 AceView cDNA sequences (see all 308):

    AW963207 AI435114 BP873250 AW245266 BM769158 AK025481 AA450197 AI554259 
    BM699032 BQ694032 NM_016107 BX955036 BX472923 AI355964 AI459130 AA322086 
    BQ219704 AI198040 BF431469 BX115375 AI239441 AA506082 BX503021 AA928638 

    highest scoring ESTs for ZFR:

    AI459274 AU117155 BC030540 BF105996 BF576282 BG023720 BG026250 BG542107 BG622066 BM801813 

    Unigene Cluster for ZFR:

    Zinc finger RNA binding protein
    Hs.435231  [show with all ESTs]
    Unigene Representative Sequence: NM_016107


    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ZFR (see all 8)

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b ^
    SP1:                                                                                                                                      -           -         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                -                                                                           
    SP5:                                                                                                                                -     -           -         

    ExUns: 19 ^ 20
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            

    About this scheme

    ECgene alternative splicing isoforms for ZFR
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507465 ENST00000502988 ENST00000416900 ENST00000382126 ENST00000510369
    ENST00000514356 ENST00000265069(uc010ium.1 uc011cny.1 uc003jhr.1)
    ENST00000505204 ENST00000505366(uc010iun.1)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    ZFR expression in normal and diseased human tissues

    1  / 2  / 3

    11 probe-sets matching ZFR gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    33148_at2, 3 U133-A 1 0.94 1.00 0.91 0.32 AI459274 0.80 1.00 0.91 1
    40610_at2, 3 U95-A 1 0.75 1.00 0.74 1.21 AI743507 0.60 1.00 0.82 1
    48848_at2, 3 U95-B 1 0.69 1.00 0.87 1.49 AW009457 0.60 1.00 0.82 1
    213286_at2, 3 U133-A 1 1.00 1.00 -- -- BF445199 0.60 1.00 0.82 1
    201856_s_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
    33148_at2, 3 U133-A 1 0.94 1.00 -- -- AI459274 0.80 1.00 0.91 1
    201857_at2, 3 U133-A 1 0.73 1.00 -- -- NM_016107 0.60 1.00 0.82 1
    213286_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    201856_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    33148_at2 U133Plus2 1 0.94 1.00 -- -- -- -- -- -- --
    201857_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
    About this table

    ZFR for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    ZFR gene expression
    ZFR gene electronic northern expression
    ZFR gene sage expression
    About these images

    CGAP SAGE TAG: ACATTCTTGT

    SOURCE GeneReport for Unigene cluster: Hs.435231

    Expression variation in blood from EXPOLDB for ZFR

    UniProtKB/Swiss-Prot: ZFR_HUMAN, Q96KR1
    Tissue specificity: Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney

    Primers: OriGene genome-wide validated SYBR primer pairs: ZFR
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ZFR: PPH13591A
        SABiosciences Custom PCR Arrays for ZFR 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for ZFR gene from 5/10 species (see all 10)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ZFR1   -- zinc finger RNA binding protein 95.52(n)
    98.4(a)
    489239  XM_849011.1  XP_854104.1 
    chimpanzee
    (Pan troglodytes)
    ZFR1   -- zinc finger RNA binding protein 99.71(n)
    99.71(a)
    461948  XM_001155241.1  XP_001155241.1 
    cow
    (Bos taurus)
    ZFR1   -- zinc finger RNA binding protein 95.23(n)
    98.26(a)
    538494  XM_580670.3  XP_580670.3 
    rat
    (Rattus norvegicus)
    Zfr1   -- zinc finger RNA binding protein 93.29(n)
    97.69(a)
    365703  XM_345169.3  XP_345170.3 
    mouse
    (Mus musculus)
    Zfr1 , 5 15 (5.90 cM)5
    zinc finger RNA binding protein1, 5 92.55(n)1
    97.62(a)1
    227631  NM_011767.11  NP_035897.11 
     AF0710595  AI8460605  (see all 23)
    About this table        Species with no ortholog for ZFR

    ENSEMBL Gene Tree for ZFR (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for ZFR gene
    ZFR22  ILF22  STRBP2  ILF32  

    ZFR for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/955 NCBI SNPs in ZFR are shown (see all 955)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 5 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs1789351,2
    C,F,O,H,32417694(-) TACTGT/CGTTTA 1 -- int114Minor allele frequency- C:0.05NS EA NA WA 642
    rs1834431,2
    C,32444286(+) TCCGGG/ACCGAG 1 -- int12Minor allele frequency- A:0.00NA WA 4
    rs1865591,2
    C,F,O,A,H,32421913(-) ATGTTA/GGTTTT 1 -- int113Minor allele frequency- G:0.47NS EA NA WA 720
    rs3244281,2
    C,F,O,A,H,32419849(-) TAGCCA/GTTGCT 1 -- int19Minor allele frequency- G:0.49NA EA WA 310
    rs3244291,2
    C,F,A,32436229(-) GGTTAC/GCAACT 1 -- int18Minor allele frequency- G:0.45NA WA 216
    rs3244301,2
    C,A,32436199(-) AGAAAT/GAAATA 1 -- int1 trp34Minor allele frequency- G:0.00NA WA 8
    rs3244311,2
    C32424497(-) cactgC/Tgccca 1 -- int14Minor allele frequency- T:0.50NA WA 8
    rs3244321,2
    C,F,A,H,32424065(-) cttgaA/Gtggtt 1 -- int111Minor allele frequency- G:0.06NS EA NA WA 502
    rs3244331,2
    C,F,O,A,H,32421850(-) ACTCTT/GTTCTA 1 -- int114Minor allele frequency- G:0.31NS EA NA WA 730
    rs3244341,2
    C,H,32445145(+) TCCTTC/AACTTT 1 -- ng518Minor allele frequency- A:0.09MN EA NA WA 1264
    About this table

    HapMap Linkage Disequilibrium images for ZFR (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ZFR
         1 CNV: 3552

    QIAGEN SeqTarget long-range PCR primers for resequencing ZFR 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/35 PubMed articles for ZFR gene, integrated from 7 sources (see all 35):
    (articles sorted by number of sources associating them with ZFR)
    1. Cloning and expression of the human single copy homologue of the mouse zinc finger protein zfr. (PubMed id 11574164)1, 2, 3 Kleines M.... Schaade L. (2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    4. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    5. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
    6. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (2007)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51663 HGNC: 17277 AceView: ZFR Ensembl:ENSG00000056097 euGenes: HUgn51663
    ECgene: ZFR H-InvDB: ZFR

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for ZFR gene:
    Search GeneIP for patents involving ZFR

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
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     ELISAs and CLIAs for ZFR
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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