Aliases &
Descriptions
for ZNF16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 161 2 | | KOX91 2 3 5 | | Zinc finger protein KOX92 3 | | zinc finger protein 16 (KOX 9)1 |
Export aliases for ZNF16 gene to outside databasesPrevious GC identifers: GC08M143762 GC08M146192 GC08M145603 GC08M146004 GC08M146006 GC08M146126 |
Summaries
for ZNF16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF16:
The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor.This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Twoalternatively spliced variants, encoding the same protein, have been identified. (provided by RefSeq)
UniProtKB/Swiss-Prot: ZNF16_HUMAN, P17020Function: May be involved in transcriptional regulation
Gene Wiki entry for ZNF16 |
Genomic Views
for ZNF16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF16 gene promoter:
GATA-1 PPAR-gamma1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF16
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF16  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24ZNF16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M141271: view genomic region
(about GC identifiers)
Start:
|
141,271,570 bp from pter |
End:
|
141,292,481 bp from pter |
Size:
|
20,912 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr8- 146,155,746-146,176,274 |
RefSeq DNA sequence:- NC_000008.10 NT_037704.5
|
Proteins
for ZNF16 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZNF16_HUMAN, P17020 (See
protein sequence)Recommended Name: Zinc finger protein 16 Size: 682 amino acids; 76472 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B3KXM4 D3DWP2 Q96FG0Explore the universe of human proteins at neXtProt for ZNF16: NX_P17020
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_001025147.2 NP_008889.2
ENSEMBL proteins: ENSP00000378369 ENSP00000276816 ENSP00000403828
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF16 for ontologies About GeneDecksing
Antibodies for ZNF16:
Assays for ZNF16: |
Protein
Domains/
Families
for ZNF16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF16 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P17020ProtoNet protein and cluster: P17020 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF16_HUMAN, P17020Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 17 C2H2-type zinc fingers |
Gene Function
for ZNF16 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZNF16_HUMAN, P17020Function: May be involved in transcriptional regulation
Genatlas biochemistry entry for ZNF16:zinc finger protein 16 (KOX9) (C2H2 type,Kruppel-like)3 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF16 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF16 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF16
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF16
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0045449 | regulation of transcription |
IEA | -- |
About this table
ZNF16 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF16
|
Transcripts
for ZNF16 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF16 gene (2 alternative transcripts): NM_001029976.2 NM_006958.2 Additional cDNA sequence: AF024700.1 AF244088.1 AK127625.1 AK226016.1 AL834451.1 BC010996.2 CR623646.1 DQ117529.1 X52340.1 4 DOTS entries: DT.211312 DT.92327154 DT.121474754 DT.99933493 24/54 AceView cDNA sequences (see all 54): NM_006958 BM470181 BC010996 AL834451 CK824650 AA913738 BG746647 BG283656 BE741789 AK127625 CR623646 T17349 AA865317 AF244088 AK096815 BG117671 BX370603 BI460932 AA564305 BG746406 CD359320 CD623490 AL560788 BI222242
 highest scoring ESTs for ZNF16:AI742655 AK127625 AL560788 BC010996 BI460932 AA417034 AA564305 AA829428 AA865317 AA872389 Unigene Cluster for ZNF16: Zinc finger protein 16 Hs.493225 [show with all ESTs]Unigene Representative Sequence: DQ117529
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF16 (see all 6)
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e |
|---|
|
| SP1: | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | - | | - | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF16
3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394909 ENST00000276816(uc003zet.2 uc003zeu.2) ENST00000435605
|
Expression
for ZNF16 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF16 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching ZNF16 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 60852_at2, 3
|
U95-C |
1 |
0.88 |
1.00 |
1.00 |
1.00 |
AI742655 |
0.80 |
1.00 |
0.91 |
1 |
| 219548_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_006958 |
0.60 |
1.00 |
0.82 |
1 |
| 219548_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF16 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AATAGAGTTT
SOURCE GeneReport for Unigene cluster: Hs.493225
SABiosciences Custom PCR Arrays for ZNF16
|
Orthologs
for ZNF16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF16 gene from 3 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
ZNF161 |
-- |
zinc finger protein 16 |
99.07(n)
98.97(a) |
464477 XM_520031.2 XP_520031.2 |
cow
(Bos taurus) |
ZNF161 |
-- |
zinc finger protein 16 |
78.14(n)
76.88(a) |
513814 XM_591561.3 XP_591561.3 |
fruit fly
(Drosophila melanogaster) |
CG147113 |
86E16 |
-- |
47(a)
(best of 9) |
-- |
About this table Species with no ortholog for ZNF16
ENSEMBL Gene Tree for ZNF16 (if available) |
Paralogs
for ZNF16 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF16 gene
- ZNF712 ZNF5012 ZFP22 ZNF6232 ZNF232 ZFP32 ZNF8522 ZNF1672
- ZNF5022 ZNF2522 ZNF6602 ZNF352
ZNF16 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF16 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 8 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF16 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZNF16
2 CNVs: 2779 70499
1 Indel: 47502 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF16 |
|
Disorders & Mutations
for ZNF16 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF16 for disorders About GeneDecksing
OMIM: 601262
Export disorders and mutations for ZNF16 gene to outside databases
|
Medical News
for ZNF16 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
9 PubMed articles for ZNF16 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF16)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. (PubMed id 11054286)1 Dreier B....Barbas C.F. (2000)
- Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149)1 Suzuki Y.... Sugano S. (1997)
- Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22. (PubMed id 7486829)1 Rousseau-Merck M.F....Thiesen H.J. (1995)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for ZNF16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF16 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF16 gene:
Search GeneIP for patents involving ZNF16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF16 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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 |  |  |  | |
| |  | Search Tocris compounds for ZNF16 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for ZNF16 |
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