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Aliases & Descriptionsfor ZNF19 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions zinc finger protein 191 2 KOX121 2 3 5 zinc finger protein 19 (KOX 12)1 2 MGC510211 2 Zinc finger protein KOX122 3
Export aliases for ZNF19 gene to outside databases Previous GC identifers: GC16U990061 GC16M072231 GC16M071217 GC16M071284 GC16M070065 GC16M071507
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Summariesfor ZNF19 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ZNF19 : The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16. (provided by RefSeq) UniProtKB/Swiss-Prot: ZNF19_HUMAN, P17023 Function : May be involved in transcriptional regulationGene Wiki entry for ZNF19
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Genomic Viewsfor ZNF19 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZNF19 gene promoter: NRSF form 1 NRSF form 2 HNF-1A AML1a Other transcription factors Search SABiosciences Chromatin IP Primers for ZNF19 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 16q22 Ensembl cytogenetic band: 16q22.2 HGNC cytogenetic band: 16q22 ZNF19 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure
GeneLoc location for GC16M057276: view genomic region
(about GC identifiers )
Start:
57,276,019 bp from pter
End:
57,291,299 bp from pter
Size:
15,281 bases
Orientation:
minus strand
1 alternative location : Chr 16- 71,507,486-71,523,241
RefSeq DNA sequence: NC_000016.9 NT_010498.15
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Proteinsfor ZNF19 gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: ZNF19_HUMAN, P17023 (See
protein sequence )Recommended Name: Zinc finger protein 19 Size : 458 amino acids; 52449 Da
Subcellular location : Nucleus (Potential)
Sequence caution : Sequence=AAA36814.1; Type=Erroneous initiation;
Secondary accessions : A8K895 Q86Y66 Q8NDE2 Q96M79 Q96NE5Alternative splicing : 2 isoforms : P17023-1 P17023-2 Explore the universe of human proteins at neXtProt for ZNF19: NX_P17023
REFSEQ proteins: NP_008892.2 ENSEMBL proteins: ENSP00000288177 ENSP00000384271 Human Recombinant Proteins 2 Gene Ontology (GO) cellular component terms (GO ID links to tree view) :
About this table
ZNF19 for ontologies About GeneDecksing Antibodies for ZNF19: Assays for ZNF19:
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Protein
Domains/ Familiesfor ZNF19 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ZNF19 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry P17023 ProtoNet protein and cluster: P17023
2 Blocks protein families : IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature UniProtKB/Swiss-Prot: ZNF19_HUMAN, P17023 Similarity : Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity : Contains 10 C2H2-type zinc fingersSimilarity : Contains 1 KRAB domain
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Gene Functionfor ZNF19 gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section UniProtKB/Swiss-Prot: ZNF19_HUMAN, P17023 Function : May be involved in transcriptional regulation
Genatlas biochemistry entry for ZNF19 :zinc finger protein 19 (KOX12) (C2H2 type,Kruppel-like) 5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6 ):
About this table
ZNF19 for ontologies About GeneDecksing
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Pathways & Interactionsfor ZNF19 gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for ZNF19 Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF19 2 Gene Ontology (GO) biological process terms (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006355 regulation of transcription, DNA-dependent
NAS 7557990 GO:0045449 regulation of transcription
-- --
About this table
ZNF19 for ontologies About GeneDecksing
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Drugs & Compoundsfor ZNF19 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for ZNF19
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Transcriptsfor ZNF19 gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for ZNF19 gene: NM_006961.3
Additional cDNA sequence: AK055567.1 AK057330.1 AK292260.1 AK311003.1 AL834237.1 BC047091.1 X52343.1
10 DOTS entries : DT.95272837 DT.99948028 DT.309678 DT.100756801 DT.120663172 DT.120663131 DT.120663181 DT.40113788
DT.95190248 DT.95272841 24/132 AceView cDNA sequences (see all 132 ):
BT007400 AL833815 AI937864 BQ000009 CK429424 AA026601 BX537507 CF890829 AA805092 BM465669 AW160828 BM310653 X52347 BC007256 N47634 BX098236 AK091039 CD623493 AF507946 CB265954 BM022007 BU684801 NM_145911 BM021862
highest scoring ESTs for ZNF19 :AI567345 DB037765 DB053318 DB079697 DB079826 DB094852 DB100078 NM_152907 AI655693 AK057330 Unigene Cluster for ZNF19:
Zinc finger protein 19 Hs.660076 [show with all ESTs ] Unigene Representative Sequence: NM_006961 GeneLoc Exon Structure 5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF19 (see all 6 ) ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c SP1 :         -   -           -               SP2 :           -       -   -   -               SP3 :                                   SP4 :         -                           SP5 :           -           -              
About this scheme ECgene alternative splicing isoforms for ZNF19 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000288177 (uc002fak.1 uc010cgc.1 uc002fal.1 uc002fam.1 )ENST00000408023
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Expression for ZNF19 gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section ZNF19 expression in normal and diseased human tissues 1 / 2 / 3
8 probe-sets matching ZNF19 gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
57108_at2 , 3
U95-C
1
0.69
1.00
0.51
1.29
AI655693
0.60
0.62
0.61
1
53695_at2 , 3
U95-B
1
0.69
1.00
0.76
0.80
AW003084
0.60
0.62
0.61
1
234953_x_at2
U133-B
30
1.00
0.65
--
--
--
--
--
--
--
228958_at2 , 3
U133-B
1
0.82
1.00
--
--
AW003084
0.60
0.62
0.61
1
240836_at2 , 3
U133-B
1
0.46
1.00
--
--
AI655693
0.60
0.62
0.61
1
234953_x_at2
U133Plus2
30
1.00
0.65
--
--
--
--
--
--
--
228958_at2
U133Plus2
1
0.82
1.00
--
--
--
--
--
--
--
240836_at2
U133Plus2
1
0.46
1.00
--
--
--
--
--
--
--
About this table
ZNF19 for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: CCTGAAGCTA SOURCE GeneReport for Unigene cluster: Hs.660076 SABiosciences Custom PCR Arrays for ZNF19
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Orthologsfor ZNF19 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for ZNF19 gene from 3 species
About this table Species with no ortholog for ZNF19 ENSEMBL Gene Tree for ZNF19 (if available)
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Paralogsfor ZNF19 gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section Paralogs for ZNF19 gene ZNF621 2 ZNF619 2 ZNF620 2
ZNF19 for paralogs About GeneDecksing
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Genomic Variantsfor ZNF19 gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 16 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for ZNF19 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ZNF19: --
QIAGEN SeqTarget long-range PCR primers for resequencing ZNF19
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Disorders & Mutationsfor ZNF19 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ZNF19 for disorders About GeneDecksing
OMIM: 194525 Export disorders and mutations for ZNF19 gene to outside databases
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Medical Newsfor ZNF19 gene (Possibly Related Articles in
Doctor's Guide )
About This Section --
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Publicationsfor ZNF19 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 10/12 PubMed articles for ZNF19 gene, integrated from 7 sources (see all 12 ): (articles sorted by number of sources associating them with ZNF19) Characterization and mapping of human genes encoding zinc finger proteins. (PubMed id 1946370) 1 , 2 , 3 Bray P.L.... Dawid I.B. (1991) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PubMed id 1505991) 1 , 3 Lichter P....Ward D.C. (1992) Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909) 1 , 2 Thiesen H.-J. (1990) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965) 1 Lamesch P.... Vidal M. (2007) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553) 2 Martin J.... Pennacchio L.A. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF19 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZNF19 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ZNF19 gene
(According to HUGE )
About This Section --
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Specialized Databases showing ZNF19 gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for ZNF19 gene: Search GeneIP for patents involving ZNF19 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ZNF19 gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for ZNF19
ELISAs and CLIAs for ZNF19
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