Aliases &
Descriptions
for ZNF215 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 2151 2 | | BAZ22 3 | | ZKSCAN111 2 3 | | BAZ-22 3 | | Zinc finger protein with KRAB and SCAN domains 112 3 | | BAZ 22 | | BWSCR2-associated zinc finger protein 22 3 | | |
Export aliases for ZNF215 gene to outside databasesPrevious GC identifers: GC11P007690 GC11P007408 GC11P006906 GC11P006911 GC11P006904 |
Summaries
for ZNF215 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN215_HUMAN, Q9UL58Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF215 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF215 gene promoter:
LCR-F1 GATA-1 AP-2rep C/EBPalpha CHOP-10 GR-alpha GR-beta Bach1 NF-AT3 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF215
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF215  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.4 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.4ZNF215 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P006606: view genomic region
(about GC identifiers)
Start:
|
6,606,247 bp from pter |
End:
|
6,637,874 bp from pter |
Size:
|
31,628 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr11+ 6,947,654-7,005,469 |
RefSeq DNA sequence:- NC_000011.9 NT_009237.18
|
Proteins
for ZNF215 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN215_HUMAN, Q9UL58 (See
protein sequence)Recommended Name: Zinc finger protein 215 Size: 517 amino acids; 60034 Da
Subcellular location: Nucleus (Probable)Explore the universe of human proteins at neXtProt for ZNF215: NX_Q9UL58
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_037382.2
ENSEMBL proteins: ENSP00000299468 ENSP00000393202 ENSP00000278319
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF215 for ontologies About GeneDecksing
Antibodies for ZNF215:
Assays for ZNF215: |
Protein
Domains/
Families
for ZNF215 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF215 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9UL58ProtoNet protein and cluster: Q9UL58 2 Blocks protein families: IPB001909 KRAB box IPB003309 Transcriptional regulator SCAN
UniProtKB/Swiss-Prot: ZN215_HUMAN, Q9UL58Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 4 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domainSimilarity: Contains 1 SCAN box domain |
Gene Function
for ZNF215 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN215_HUMAN, Q9UL58Function: May be involved in transcriptional regulation
5 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF215 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF215 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF215
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF215
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
NAS | -- | | GO:0016032 | viral reproduction |
IEA | -- |
About this table
ZNF215 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF215 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF215
|
Transcripts
for ZNF215 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF215 gene: NM_013250.2 Additional cDNA sequence: AF056618.1 AK298365.1 AK302639.1 BC014538.1 2 DOTS entries: DT.100647711 DT.75176959 24/30 AceView cDNA sequences (see all 30): AA721335 AI424805 AA911733 AA829377 AI810619 BU622513 AI684939 AF056618 AA724860 CN483744 BX117423 AI962824 AA639668 AA481227 NM_013250 AI636885 AA481148 AI633862 CB130717 BC014538 AW295091 AW873531 AW511358 BM798335
 highest scoring ESTs for ZNF215:AA481227 AA527514 AA721335 AA724860 AA829377 AA911733 AF056618 AI424805 AI636885 AW295091 Unigene Cluster for ZNF215: Zinc finger protein 215 Hs.523457 [show with all ESTs]Unigene Representative Sequence: NM_013250
GeneLoc Exon Structure
3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000299468(uc001mez.1) ENST00000414517(uc010raw.1 uc010rax.1)
ENST00000278319(uc001mey.2)
|
Expression
for ZNF215 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF215 expression in normal and diseased human tissues
1 / 2 / 3 6 probe-sets matching ZNF215 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 84172_s_at2, 3
|
U95-D |
1 |
0.75 |
1.00 |
-0.17 |
0.25 |
AI424805 |
0.80 |
1.00 |
0.91 |
1 |
| 84176_r_at2, 3
|
U95-D |
1 |
0.75 |
1.00 |
0.57 |
0.44 |
AI636885 |
0.80 |
1.00 |
0.91 |
1 |
| 55892_at2, 3
|
U95-C |
1 |
0.56 |
1.00 |
1.00 |
1.00 |
AA527514 |
0.80 |
1.00 |
0.91 |
1 |
| 84174_r_at2, 3
|
U95-D |
1 |
0.44 |
1.00 |
-0.20 |
0.56 |
AI424805 |
0.80 |
1.00 |
0.91 |
1 |
| 220214_at2, 3
|
U133-A |
1 |
0.73 |
1.00 |
-- |
-- |
NM_013250 |
0.60 |
1.00 |
0.82 |
1 |
| 220214_at2
|
U133Plus2 |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF215 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GCCCTGTACT
SOURCE GeneReport for Unigene cluster: Hs.523457
SABiosciences Custom PCR Arrays for ZNF215
|
Orthologs
for ZNF215 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF215 gene from 3 species
About this table Species with no ortholog for ZNF215
ENSEMBL Gene Tree for ZNF215 (if available) |
Paralogs
for ZNF215 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF215 gene
- ZSCAN182 ZNF2742 ZNF4832 ZSCAN12
ZNF215 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF215 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 11 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF215 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF215
1 CNV: 101121 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF215 |
|
Disorders & Mutations
for ZNF215 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF215 for disorders About GeneDecksing
OMIM: 605016
Export disorders and mutations for ZNF215 gene to outside databases
|
Medical News
for ZNF215 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF215 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
4 PubMed articles for ZNF215 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF215)- Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome. (PubMed id 10762538)1, 2 Alders M.... Mannens M. (2000)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- An integrated physical map of 210 markers assigned to the short arm of human chromosome 11. (PubMed id 7959730)1 Redeker E....van den Bogaard R. (1994)
|
External Searches for ZNF215 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF215 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF215 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF215 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF215 gene:
Search GeneIP for patents involving ZNF215
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF215 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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