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ZNF238 Gene

protein-coding   GIFtS: 52

GC01P214598
zinc finger protein 238
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for ZNF238 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
zinc finger protein 2381 2     Zinc finger and BTB domain-containing protein 182 3
RP581 2 3 5     Zinc finger protein C2H2-1712 3
ZBTB181 2 3     Translin-associated zinc finger protein 12 3
TAZ-11 2 3     58 kDa repressor protein2 3
C2H2-1711 2     TAZ13
Transcriptional repressor RP582 3     

External Ids:    HGNC: 130301   Entrez Gene: 104722   Ensembl: ENSG000001794567   UniProtKB: Q995923   

Export aliases for ZNF238 gene to outside databases

Previous GC identifers: GC01P242102 GC01P239460 GC01P240413 GC01P241161 GC01P240540 GC01P242281 GC01P244215


Summaries
for ZNF238 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ZNF238:
C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors
and are involved in chromatin assembly.(supplied by OMIM)

UniProtKB/Swiss-Prot: ZN238_HUMAN, Q99592
Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain
development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of
skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of
postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3'
which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a
role in the organization of chromosomes in the nucleus

Gene Wiki entry for ZNF238

Genomic Views
for ZNF238 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF238 gene promoter:
         Meis-1   HOXA9B   Nkx6-1   MEF-2A   FOXD1   IRF-7A   Arnt   c-Myc   Max1   E4BP4   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ZNF238

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF238 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44-qter   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44-ter

ZNF238 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF238 gene location

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P214598:  view genomic region     (about GC identifiers)

Start:
 214,598,471 bp from pter
End:
 214,604,688 bp from pter
Size:
 6,218 bases
Orientation:
 plus strand

1 alternative location:
Chr1+ 244,214,561-244,220,778     
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  

Proteins
for ZNF238 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: ZN238_HUMAN, Q99592 (See protein sequence)
Recommended Name: Zinc finger protein 238  
Size: 522 amino acids; 58354 Da
Subunit: Interacts with DNMT3A
Subcellular location: Nucleus. Note=Associates with condensed chromatin
Secondary accessions: A8K5U3 Q13397 Q5VU40 Q8N463 Q9UD99
Alternative splicing: 2 isoforms:  Q99592-1   Q99592-2   

Explore the universe of human proteins at neXtProt for ZNF238: NX_Q99592 

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_006343.2  NP_991331.1  


    ENSEMBL proteins: 
    ENSP00000355496 ENSP00000351539 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: ZNF238
    GenScript Custom Purified and Recombinant Proteins Services for ZNF238 
    Novus Biologicals Proteins for ZNF238
    Novus Biologicals Lysates for ZNF238
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228 nuclear chromosome TAS9756912
    GO:0005622 intracellular IEA--
    GO:0005634 nucleus TAS9013868
    About this table

    ZNF238 for ontologies           About GeneDecksing



    Antibodies for ZNF238: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ZNF238
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for ZNF238 
    Novus Biologicals Antibodies for ZNF238
    Browse antibodies at Epitomics

    Assays for ZNF238: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF238 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ZNF238 

    Protein Domains/
    Families
    for ZNF238 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZNF238 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR000210 BTB/POZ-like
     IPR015880 Znf_C2H2-like
     IPR011333 BTB/POZ_fold
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q99592

    ProtoNet protein and cluster: Q99592

    2 Blocks protein families:
    IPB000210 BTB/POZ domain
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN238_HUMAN, Q99592
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 4 C2H2-type zinc fingers


    Gene Function
    for ZNF238 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: ZN238_HUMAN, Q99592
    Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain
    development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of
    skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of
    postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3'
    which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a
    role in the organization of chromosomes in the nucleus

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and siRNA for ZNF238
    Sigma-Aldrich shRNA for ZNF238
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZNF238
    OriGene shRNA RFP (see all 2): ZNF238
    OriGene basic RS shRNA (see all 2): ZNF238
    OriGene siRNA (see all 2): ZNF238
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF238 
    miRNA:Sigma-Aldrich microRNA Mimics for ZNF238
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF238 
    8/49 SABiosciences Assays for microRNAs that regulate ZNF238 (see all 49):
    hsa-miR-361-5p hsa-miR-513a-5p hsa-miR-199a-3p hsa-miR-106a hsa-miR-200a hsa-miR-219-5p hsa-miR-301a hsa-miR-519a

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene 3'-UTR clone (see all 2): ZNF238 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ZNF238 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for ZNF238 

    Genatlas biochemistry entry for ZNF238:
    zinc finger protein C2H2,preferentially expressed in brain

    5/7 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 7):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677 DNA binding TAS9013868
    GO:0003700 sequence-specific DNA binding transcription factor activity TAS9770450
    GO:0005515 protein binding IEA--
    GO:0008270 zinc ion binding IEA--
    GO:0016564 transcription repressor activity ISS--
    About this table

    ZNF238 for ontologies           About GeneDecksing

    Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Zfp238):

    lethality-prenatal/perinatalnervous system

    ZNF238 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ZNF238 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for ZNF238 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF238

    5 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0007275 multicellular organismal development IEA--
    GO:0007519 skeletal muscle tissue development ISS--
    GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter IEA--
    GO:0045449 regulation of transcription IEA--
    About this table

    ZNF238 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZNF238 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF238


    Transcripts
    for ZNF238 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and siRNA for ZNF238
    Sigma-Aldrich shRNA for ZNF238
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZNF238
    OriGene shRNA RFP (see all 2): ZNF238
    OriGene basic RS shRNA (see all 2): ZNF238
    OriGene siRNA (see all 2): ZNF238
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF238 
    miRNA: Sigma-Aldrich microRNA Mimics for ZNF238
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF238 
    8/49 SABiosciences Assays for microRNAs that regulate ZNF238 (see all 49):
    hsa-miR-361-5p hsa-miR-513a-5p hsa-miR-199a-3p hsa-miR-106a hsa-miR-200a hsa-miR-219-5p hsa-miR-301a hsa-miR-519a
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene untagged cDNA clones in CMV expression vector (see all 2): ZNF238
    OriGene 3'-UTR Clone (see all 2): ZNF238 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: ZNF238 
    Primers: OriGene genome-wide validated SYBR primer pairs: ZNF238
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ZNF238: PPH21418A

    REFSEQ mRNAs for ZNF238 gene (2 alternative transcripts): 

    NM_006352.3  NM_205768.2  

    Additional cDNA sequence: 

    AJ001388.1 AK291408.1 AK293892.1 AK310634.1 AL050055.1 BC036677.2 BC078175.1 U38896.1 
    X95072.1 

    8 DOTS entries:

    DT.100813582  DT.413626  DT.92425268  DT.95090455  DT.75102535  DT.100813581  DT.121505004  DT.92425274 

    24/47 AceView cDNA sequences (see all 47):

    BX419577 BM475884 T05975 BX440836 NM_205768 BQ220621 AA301315 AA334942 
    AA331555 T32155 T07956 AA349504 AA347500 BM562720 T30905 T32158 
    CB147016 BC036677 AW665310 U38896 CB216500 AA426106 BQ882698 T30946 

    highest scoring ESTs for ZNF238:

    U38896 AA176381 AA303233 AA315131 AA331555 AA334942 AA347500 AA349503 AA349504 AA406525 

    Unigene Cluster for ZNF238:

    Zinc finger protein 238
    Hs.69997  [show with all ESTs]
    Unigene Representative Sequence: BC078175


    GeneLoc Exon Structure

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366538(uc001iaf.1 uc001iad.3) ENST00000358704(uc001iae.2)


    Expression
    for ZNF238 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    ZNF238 expression in normal and diseased human tissues

    1  / 2  / 3

    6 probe-sets matching ZNF238 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    35825_s_at2, 3 U95-A 1 1.00 1.00 0.94 0.61 U38896 1.00 1.00 1.00 1
    35824_at2, 3 U95-A 2 1.00 0.97 0.98 1.39 AJ223321 0.20 1.00 0.72 1
    212774_at2, 3 U133-A 2 1.00 0.91 -- -- AJ223321 0.20 1.00 0.72 1
    207164_s_at2, 3 U133-A 1 0.91 1.00 -- -- NM_006352 0.60 1.00 0.82 1
    212774_at2 U133Plus2 2 1.00 0.91 -- -- -- -- -- -- --
    207164_s_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
    About this table

    ZNF238 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    ZNF238 gene expression
    ZNF238 gene electronic northern expression
    ZNF238 gene sage expression
    About these images

    CGAP SAGE TAG: GAAAACGTTT

    SOURCE GeneReport for Unigene cluster: Hs.69997

    Expression variation in blood from EXPOLDB for ZNF238

    UniProtKB/Swiss-Prot: ZN238_HUMAN, Q99592
    Tissue specificity: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level,
    other tissues

    Primers: OriGene genome-wide validated SYBR primer pairs: ZNF238
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for ZNF238: PPH21418A
        SABiosciences Custom PCR Arrays for ZNF238 


    Orthologs
    for ZNF238 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ZNF238 gene from 5/10 species (see all 10)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 ZNF2381   -- zinc finger protein 238 94.16(n)
    97.36(a)    		 490376  XM_547497.2  XP_547497.2 
    chimpanzee
    (Pan troglodytes)    		 ZNF2381   -- zinc finger protein 238 99.69(n)
    99.81(a)    		 469733  XM_525117.2  XP_525117.2 
    cow
    (Bos taurus)    		 ZNF2381   -- zinc finger protein 238 96.81(n)
    99.23(a)    		 538793  XM_001250662.1  XP_001250663.1 
    rat
    (Rattus norvegicus)    		 Zfp2381   -- zinc finger protein 238 95.72(n)
    98.85(a)    		 64619  NM_022678.1  NP_073169.1 
    mouse
    (Mus musculus)    		 Zfp2381 , 5 1 (82.72 cM)5
    		 zinc finger protein 2381, 5 95.86(n)1
    99.44(a)1    		 309281  NM_001012330.11  NP_001012330.11 
     AF1402245  AI8448025  (see all 14)
    About this table        Species with no ortholog for ZNF238

    ENSEMBL Gene Tree for ZNF238 (if available)

    Paralogs
    for ZNF238 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for ZNF238 gene
    ZBTB32  ZBTB52  ZBTB492  HIC12  ZBTB422  HIC22  GZF12  MYNN2  
    ZBTB172  

    ZNF238 for paralogs           About GeneDecksing



    Genomic Variants
    for ZNF238 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/62 NCBI SNPs in ZNF238 are shown (see all 62)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 1 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs10488241,2
    		H244217498(+) GGAAGA/GAGATG 4 E G ref1 mis1 trp35Minor allele frequency- G:0.00MN NS EA 586
    rs13896221,2
    		C,F,244215864(-) ACTTCC/TCCTTT 2 -- ng51 int1 trp38Minor allele frequency- T:0.11MN EA NA WA 2070
    rs24531891,2
    		C244213775(+) ACACAG/CATCAA 1 -- ng51 tfbs34Minor allele frequency- C:0.00NS EA 414
    rs24865361,2
    		C,H,244219563(+) AAATAG/ACACCA 2 -- ut31 ese36Minor allele frequency- A:0.01NS NA WA 130
    rs32102021,2
    		C244220589(+) ATTGCT/CTTTTC 2 -- ut311Minor allele frequency- C:0.00MN 184
    rs38404471,2
    		--244214951(+) ACTTT-/TAATAC 2 -- ng51 int10--------
    rs64294471,2
    		C,F,A,244214095(+) GTATAC/ACATTA 1 -- ng514Minor allele frequency- A:0.01NS EA 418
    rs75191371,2
    		H244215734(+) AGTCTG/CTCTTG 2 -- int1 ng514Minor allele frequency- C:0.00NS EA 418
    rs114340651,2
    		--244216543(+) TTTCA-/ATTTTT 2 -- ng51 int1 trp30--------
    rs115887911,2
    		C,H244217719(+) ACGCCA/TCAGCA 4 T S ref1 mis1 ese34Minor allele frequency- T:0.00NS EA 418
    About this table

    HapMap Linkage Disequilibrium images for ZNF238 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ZNF238: --

    QIAGEN SeqTarget long-range PCR primers for resequencing ZNF238 

    Disorders & Mutations
    for ZNF238 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ZNF238 for disorders           About GeneDecksing

    OMIM: 608433

    1 PharmGKB disease relationship for ZNF238 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Leukemia, Lymphocytic, Acute, L1FA  GN  12730115
    About this table


    Export disorders and mutations for ZNF238 gene to outside databases

    Medical News
    for ZNF238 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for ZNF238 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/27 PubMed articles for ZNF238 gene, integrated from 7 sources (see all 27):
    (articles sorted by number of sources associating them with ZNF238)
    1. Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin. (PubMed id 10721697)1, 2, 7 Meng G....Kasai M. (2000)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. (PubMed id 11350943)1, 2 Fuks F.... Kouzarides T. (2001)
    5. RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression. (PubMed id 9756912)1, 2 Aoki K.... Kasai M. (1998)
    6. Isolation and characterization of a cDNA encoding a translin-like protein, TRAX. (PubMed id 9013868)1, 3 Aoki K.... Kasai M. (1997)
    7. C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain. (PubMed id 9568537)1, 3 Becker K.G....Drew P.D. (1997)
    8. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PubMed id 7633419)1, 2 Becker K.G....Drew P.D. (1995)
    9. ZNF238 is expressed in postmitotic brain cells and in hibits brain tumor growth. (PubMed id 20103640)1 Tatard V.M....Dahmane N. (2010)
    10. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)

    External Searches for ZNF238 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ZNF238 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10472 HGNC: 13030 AceView: ZNF238 Ensembl:ENSG00000179456 euGenes: HUgn10472
    ECgene: ZNF238 H-InvDB: ZNF238

    Other Databases showing ZNF238 gene

    (According to HUGE)
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    Specialized Databases showing ZNF238 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    Intellectual Property
    for ZNF238 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    		Patent Information for ZNF238 gene:
    Search GeneIP for patents involving ZNF238

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    Products
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