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Aliases & Descriptionsfor ZNF33B gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions zinc finger protein 33B1 2 Zinc finger protein 11B1 3 KOX21 2 3 5 Zinc finger protein KOX22 3 ZNF11B2 3 5 FLJ233272 KOX311 2 MGC1296962 zinc finger protein 33b (KOX 31)1 2 zinc finger protein 11b (KOX 2)2
Export aliases for ZNF33B gene to outside databases Previous GC identifers: GC10M042377 GC10U900001 GC10P038188 GC07P006406 GC03P044571 GC10M042405 GC10M043069
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Summariesfor ZNF33B gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732 Function : May be involved in transcriptional regulationGene Wiki entry for ZNF33B
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Genomic Viewsfor ZNF33B gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for ZNF33B Other transcription factors Search SABiosciences Chromatin IP Primers for ZNF33B Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF33B
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q11.2 Ensembl cytogenetic band: 10q11.21 HGNC cytogenetic band: 10q11.2 ZNF33B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10M039611: view genomic region
(about GC identifiers )
Start:
39,611,330 bp from pter
End:
39,660,708 bp from pter
Size:
49,379 bases
Orientation:
minus strand
1 alternative location : Chr 10- 43,069,633-43,134,285
RefSeq DNA sequence: NC_000010.10 NT_033985.7
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Proteinsfor ZNF33B gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732 (See
protein sequence )Recommended Name: Zinc finger protein 33B Size : 778 amino acids; 90683 Da
Subcellular location : Nucleus (Potential)
Sequence caution : Sequence=AAH48313.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence;
Secondary accessions : Q06731 Q32MA2 Q86XY8 Q8NDW3Explore the universe of human proteins at neXtProt for ZNF33B: NX_Q06732 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins: NP_008886.1 ENSEMBL proteins: ENSP00000352444 ENSP00000392313 ENSP00000379177 ENSP00000402467 Human Recombinant Proteins 2 Gene Ontology (GO) cellular component terms (GO ID links to tree view) :
About this table
ZNF33B for ontologies About GeneDecksing Antibodies for ZNF33B: Assays for ZNF33B:
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Protein
Domains/ Familiesfor ZNF33B gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ZNF33B for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q06732 ProtoNet protein and cluster: Q06732
2 Blocks protein families : IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732 Similarity : Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity : Contains 16 C2H2-type zinc fingersSimilarity : Contains 1 KRAB domain
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Gene Functionfor ZNF33B gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732 Function : May be involved in transcriptional regulation
Genatlas biochemistry entry for ZNF33B :zinc finger protein 33b (KOX31) (C2H2 type,Kruppel-like) 5 Gene Ontology (GO) molecular function terms (GO ID links to tree view) :
About this table
ZNF33B for ontologies About GeneDecksing
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Pathways & Interactionsfor ZNF33B gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for ZNF33B Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF33B 2 Interacting proteins for ZNF33B (Q06732 2 ) via UniProtKB, MINT, and/or STRING About this table 1 Gene Ontology (GO) biological process term (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006355 regulation of transcription, DNA-dependent
NAS --
About this table
ZNF33B for ontologies About GeneDecksing
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Drugs & Compoundsfor ZNF33B gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for ZNF33B
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Transcriptsfor ZNF33B gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for ZNF33B gene: NM_006955.1
Additional cDNA sequence: AF027147.1 AF222749.1 AJ491697.1 AK025638.1 AK096683.1 AK304306.1 AK309564.1 AK310073.1 BC035770.1 BC036398.1 BC042873.1 BC048313.2 BC065181.1 BC107726.1 BC109232.2 BC160932.1 CR619942.1 X52333.1 X68684.1
9 DOTS entries : DT.97812540 DT.100028161 DT.100790224 DT.98083450 DT.121245221 DT.100790219 DT.100790220 DT.121245189
DT.450526
highest scoring ESTs for ZNF33B :X68688 AJ491697 AK096683 AL539493 BC036398 BC048313 BC065181 BC107726 BC109232 BE464339 Unigene Cluster for ZNF33B:
Zinc finger protein 33B Hs.499453 [show with all ESTs ] Unigene Representative Sequence: BC036398 GeneLoc Exon Structure 5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF33B (see all 9 ) ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d SP1 :         -         -   -           SP2 :         -         -   -           SP3 :         -                     SP4 :         -         -   -           SP5 :         -       -   -   -          
About this scheme ECgene alternative splicing isoforms for ZNF33B 10 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000462075 (uc001jad.2 ) ENST00000486187 (uc009xmg.1 uc001jae.1 )ENST00000465206 ENST00000359467 (uc001jaf.1 uc001jag.1 ) ENST00000476796 ENST00000493285 ENST00000486614 ENST00000416780 ENST00000395836 ENST00000432900
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Expression for ZNF33B gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section ZNF33B expression in normal and diseased human tissues 1 / 2 / 3
6 probe-sets matching ZNF33B gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
32429_f_at2 , 3
U95-A
2
0.83
0.90
0.43
0.64
X68688
0.20
1.00
0.72
1
71834_at2 , 3
U95-D
2
0.62
0.91
0.71
1.04
AA936524
0.20
0.33
0.27
1
85986_at2
U95-E
2
0.50
0.59
0.14
1.33
--
--
--
--
--
215022_x_at2
U133-A
2
0.91
0.85
--
--
--
--
--
--
--
215022_x_at2
U133Plus2
2
0.91
0.85
--
--
--
--
--
--
--
1562743_at2
U133Plus2
1
0.46
1.00
--
--
--
--
--
--
--
About this table
ZNF33B for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --SOURCE GeneReport for Unigene cluster: Hs.499453 SABiosciences Custom PCR Arrays for ZNF33B
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Orthologsfor ZNF33B gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for ZNF33B gene from 2 species
About this table Species with no ortholog for ZNF33B ENSEMBL Gene Tree for ZNF33B (if available)
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Paralogsfor ZNF33B gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section Paralogs for ZNF33B gene ZNF334 2 MIR4273 2 ZNF510 2 ENSG00000215756 2 ZNF33A 2 ZNF567 2 ZNF487P 2 ZNF37A 2 ZNF382 2
ZNF33B for paralogs About GeneDecksing
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Genomic Variantsfor ZNF33B gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 10 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for ZNF33B (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for ZNF33B 4 CNVs : 9147 3797 2862 2152
QIAGEN SeqTarget long-range PCR primers for resequencing ZNF33B
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Disorders & Mutationsfor ZNF33B gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ZNF33B for disorders About GeneDecksing
OMIM: 194522 Human Genome Epidemiology (HuGE) Navigator: ZNF33B (1 document)Export disorders and mutations for ZNF33B gene to outside databases
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Medical Newsfor ZNF33B gene (Possibly Related Articles in
Doctor's Guide )
About This Section --
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Publicationsfor ZNF33B gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 10/11 PubMed articles for ZNF33B gene, integrated from 7 sources (see all 11 ): (articles sorted by number of sources associating them with ZNF33B) Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PubMed id 8464732) 1 , 2 , 7 Tunnacliffe A.... Ponder B.A. (1993) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 1 , 2 Deloukas P.... Rogers J. (2004) Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. (PubMed id 12566394) 1 , 2 Guy J....Jackson M.S. (2003) Twenty-seven nonoverlapping zinc finger cDNAs from hu man T cells map to nine different chromosomes with apparent clustering. (PubMed id 2014798) 1 , 3 Huebner K....Thiesen H.J. (1991) Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909) 1 , 2 Thiesen H.-J. (1990) A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451) 1 Grupe A....Goate A. (2006) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 1 Stelzl U.... Wanker E.E. (2005) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 Ota T.... Sugano S. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF33B gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZNF33B gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ZNF33B gene
(According to HUGE )
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Specialized Databases showing ZNF33B gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for ZNF33B gene: Search GeneIP for patents involving ZNF33B GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ZNF33B gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for ZNF33B
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