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ZNF395 Gene

protein-coding GIFtS: 48

GC08M026748

zinc finger protein 395
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
zinc finger protein 395¹ ²		HDRF-2² ³
PBF¹ ² ³		HD gene regulatory region-binding protein 2² ³
PRF-1¹ ² ³		HD-regulating factor 2² ³
HDBP2¹ ² ³		HDBP-2² ³
DKFZp434K1210¹ ²		PRF1²
Papillomavirus regulatory factor 1² ³		papillomavirus regulatory factor PRF-1²
Papillomavirus-binding factor² ³		Huntington's disease gene regulatory region-binding protein 2²
Huntington disease gene regulatory region-binding protein 2² ³		Si-1-8-14²

External Ids:	HGNC: 18737¹	Entrez Gene: 55893²	Ensembl: ENSG00000186918⁷	UniProtKB: Q9H8N7³

Export aliases for ZNF395 gene to outside databases

Previous GC identifers: GC08M028228 GC08M028260 GC08M028261

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN395_HUMAN, Q9H8N7

Function: Plays a role in papillomavirus genes transcription

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZNF395 gene promoter:
         FOXD1   Bach1   GATA-3   GATA-2   GATA-1   Arnt   c-Myc   Max   FOXF2   FOXO1a
         Other transcription factors

Search SABiosciences Chromatin IP Primers for ZNF395

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF395

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.1 Ensembl cytogenetic band: 8p21.1 HGNC cytogenetic band: 8p21

ZNF395 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF395 gene location

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M026748: view genomic region (about GC identifiers)

Start:	26,748,397 bp from pter
End:	26,789,214 bp from pter
Size:	40,818 bases
Orientation:	minus strand

1 alternative location:

Chr8- 28,203,102-28,260,218

RefSeq DNA sequence:

NC_000008.10 NT_167187.1

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ZN395_HUMAN, Q9H8N7 (See protein sequence)

Recommended Name: Zinc finger protein 395

Size: 513 amino acids; 54939 Da

Subunit: Interacts with repression-mediating E2 binding site P2 of human papillomavirus type 8 (HPV8)

Subcellular location: Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm

Secondary accessions: B3KUY7 Q6F6H2 Q9BY72 Q9NPB2 Q9NS57 Q9NS58 Q9NS59

Explore the universe of human proteins at neXtProt for ZNF395: NX_Q9H8N7

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_061130.1

ENSEMBL proteins:

ENSP00000429640 ENSP00000427812 ENSP00000340494 ENSP00000427719 ENSP00000429649 ENSP00000429823

ENSP00000430203 ENSP00000427934 ENSP00000428452

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: ZNF395
	GenScript Custom Purified and Recombinant Proteins Services for ZNF395
	Novus Biologicals Lysate for ZNF395
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IDA	14625278
GO:0005737	cytoplasm	IDA	14625278

About this table

ZNF395 for ontologies About GeneDecksing

Antibodies for ZNF395:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ZNF395
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies
	GenScript Custom Superior Antibodies Services for ZNF395
	Novus Biologicals Antibodies for ZNF395
	Browse antibodies at Epitomics

Assays for ZNF395:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZNF395
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ZNF395

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF395 for domains About GeneDecksing

2 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q9H8N7

ProtoNet protein and cluster: Q9H8N7

UniProtKB/Swiss-Prot: ZN395_HUMAN, Q9H8N7

Similarity: Contains 1 C2H2-type zinc finger

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ZN395_HUMAN, Q9H8N7

Function: Plays a role in papillomavirus genes transcription

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for ZNF395 Sigma-Aldrich shRNA for ZNF395
		OriGene 29mer shRNA kits in GFP-retroviral vector: ZNF395 OriGene shRNA RFP: ZNF395 OriGene basic RS shRNA: ZNF395 OriGene siRNA: ZNF395
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF395

miRNA:		Sigma-Aldrich microRNA Mimics for ZNF395 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF395
		8/20 SABiosciences Assays for microRNAs that regulate ZNF395 (see all 20):
		hsa-miR-1178 hsa-miR-323-3p hsa-miR-548j hsa-miR-548i hsa-miR-9 hsa-miR-23a hsa-miR-548a-5p hsa-miR-548d-5p

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: ZNF395 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF395 OriGene untagged cDNA clones in CMV expression vector: ZNF395 OriGene 3'-UTR clone: ZNF395 Browse MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: ZNF395
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for ZNF395

3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IDA	14625278
GO:0008270	zinc ion binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

ZNF395 for ontologies About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for ZNF395

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZNF395

1 Interacting protein for ZNF395 (Q9H8N7²) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946²	MINT-8007819 MINT-8007826

About this table

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	IC	14625278

About this table

ZNF395 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF395

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for ZNF395 Sigma-Aldrich shRNA for ZNF395
		OriGene 29mer shRNA kits in GFP-retroviral vector: ZNF395 OriGene shRNA RFP: ZNF395 OriGene basic RS shRNA: ZNF395 OriGene siRNA: ZNF395
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF395

miRNA:		Sigma-Aldrich microRNA Mimics for ZNF395 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF395
		8/20 SABiosciences Assays for microRNAs that regulate ZNF395 (see all 20):
		hsa-miR-1178 hsa-miR-323-3p hsa-miR-548j hsa-miR-548i hsa-miR-9 hsa-miR-23a hsa-miR-548a-5p hsa-miR-548d-5p

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: ZNF395 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF395 OriGene untagged cDNA clones in CMV expression vector: ZNF395 OriGene 3'-UTR Clone: ZNF395 Browse OriGene MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: ZNF395

Primers:		OriGene genome-wide validated SYBR primer pairs: ZNF395 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for ZNF395: PPH08750A

REFSEQ mRNAs for ZNF395 gene:

NM_018660.2

Additional cDNA sequence: AB044751.1

17 DOTS entries:

DT.75114880 DT.100676285 DT.100787299 DT.100787298 DT.104415 DT.91684182 DT.100787301 DT.92429976

DT.120631094 DT.92067568 DT.100787307 DT.95153078 DT.100708637 DT.120631097 DT.92429973 DT.100787309

DT.95124304

24/401 AceView cDNA sequences (see all 401):

BP374773 AA347918 AI057234 BU729352 BE615116 AA972138 BM452092 BF445501

AA122378 BQ030068 AI361169 Z39516 AL527398 AI333169 AF263928 AA701339

BU580646 AI335635 AK002050 AL526737 BC001237 AI700223 BE255923 R63270

highest scoring ESTs for ZNF395:

AB057659 AK002050 AK023418 AL039400 AU137938 AU279892 N25612 N36098 N44101 AA347917

Unigene Clusters for ZNF395:

Zinc finger protein 395

Hs.435535 [show with all ESTs], Hs.695998

Unigene Representative Sequences: NM_018660, BP231545

GeneLoc Exon Structure

5/21 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF395 (see all 21)

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5a	·	5b	^	6a	·	6b	·	6c	^	7a	·	7b	^	8	^	9	^	10	^	11a	·	11b	·	11c	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·
SP1:					-
SP2:					-				-
SP3:																																							-		-		-		-		-		-		-
SP4:
SP5:																																							-		-		-		-				-

ExUns:	18b	^	19a	·	19b	·	19c	·	19d	·	19e	^	20a	·	20b	^	21	^	22	^	23	^	24	^	25	^	26a	·	26b	^	27	^	28a	·	28b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for ZNF395
11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000523202 ENST00000521185 ENST00000344423(uc003xgq.2 uc003xgr.2 uc003xgs.2 uc003xgt.2)

ENST00000520535 ENST00000519730 ENST00000517459 ENST00000522795 ENST00000517372

ENST00000520290 ENST00000521912 ENST00000523095

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ZNF395 expression in normal and diseased human tissues

¹ / ² / ³

16 probe-sets matching ZNF395 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
51543_at²^{, 3}	U95-B	1	1.00	1.00	0.77	0.99	N36098	0.80	0.88	0.84	1
64071_at²^{, 3}	U95-C	1	1.00	1.00	0.63	0.95	N25612	0.80	0.88	0.84	1
44682_at²^{, 3}	U95-B	1	0.94	1.00	0.66	1.45	AL039400	0.80	0.88	0.84	1
78133_at²^{, 3}	U95-E	1	0.88	1.00	0.50	0.64	N44101	0.60	1.00	0.82	1
218149_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_017606	0.20	1.00	0.72	1
221123_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_018660	0.60	0.83	0.73	1
223216_x_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC001237	0.60	0.83	0.73	1
232693_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AK021850	0.40	0.75	0.60	1
222536_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	N36098	0.80	0.88	0.84	1
232694_at²^{, 3}	U133-B	1	0.36	1.00	--	--	AK021850	0.40	0.75	0.60	1
218149_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
221123_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
223216_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
232693_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
222536_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
232694_at²	U133Plus2	1	0.36	1.00	--	--	--	--	--	--	--

About this table

ZNF395 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

ZNF395 gene electronic northern expression

About these images

CGAP SAGE TAG: GCCACGTTGT GCGAGTGTCC

SOURCE GeneReport for Unigene clusters: Hs.435535 Hs.695998

UniProtKB/Swiss-Prot: ZN395_HUMAN, Q9H8N7

Tissue specificity: Widely expressed

Primers:		OriGene genome-wide validated SYBR primer pairs: ZNF395 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for ZNF395: PPH08750A

SABiosciences Custom PCR Arrays for ZNF395

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ZNF395 gene from 5/10 species (see all 10)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ZNF395¹	--	zinc finger protein 395	87.59(n) 89.94(a)	486094 XM_543220.2 XP_543220.2
chimpanzee (Pan troglodytes)	ZNF395¹	--	zinc finger protein 395	99.22(n) 99.61(a)	464084 XM_519685.2 XP_519685.2
cow (Bos taurus)	ZNF395¹	--	zinc finger protein 395	86.79(n) 88.33(a)	509082 XM_585970.3 XP_585970.3
rat (Rattus norvegicus)	Zfp395¹	--	zinc finger protein 395	80.9(n) 81.03(a)	305972 XM_224298.4 XP_224298.4
mouse (Mus musculus)	Zfp395⁵	14 (34.32 cM)	zinc finger protein 395	--	CF737135

About this table Species with no ortholog for ZNF395

ENSEMBL Gene Tree for ZNF395 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ZNF395 gene

ZNF704² SLC2A4RG²

ZNF395 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs757^1,2	C,F,	28244724(+)	`CTTGGG/ATTTAA`	1	--	ng5¹		12	NS EA NA WA	638
rs351779^1,2	C,F,O,A,	28204264(-)	`CTTGAC/TACATG`	1	--	ut3¹ ese³		32	EA NA MN NS WA	2210
rs351780^1,2	C,A,H,	28203937(-)	`CCACCA/CGTGCT`	1	--	ut3¹ ese³		9	MN NA EA WA	315
rs714120^1,2	C,F,A,	28236760(+)	`CTCATA/GTCCCT`	1	--	int¹		15	NS EA NA WA	1176
rs872394^1,2	H	28207920(+)	`TCTACG/ATGCTA`	1	--	int¹		5	MN NS EA	602
rs872395^1,2	--	28208007(+)	`CAAAAG/AAGGCC`	1	--	int¹		1	MN	184
rs873373^1,2	H	28207813(+)	`ACACTC/TGGCTT`	1	--	int¹		8	EA NA MN NS	638
rs904051^1,2	C,H,	28208621(-)	`ttcctA/Gcgggc`	1	--	int¹		15	EA NA MN NS WA	668
rs904052^1,2	C,H,	28208396(-)	`GGTGAC/TATTTA`	1	--	int¹		12	MN NS EA NA WA	616
rs904053^1,2	C,F,O,	28202936(-)	`TATACA/GTGGGT`	1	--	ng3¹		14	EA NA NS	832

About this table

HapMap Linkage Disequilibrium images for ZNF395 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF395: --

QIAGEN SeqTarget long-range PCR primers for resequencing ZNF395

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNF395 for disorders About GeneDecksing

OMIM: 609494

1 Novoseek disease relationship for ZNF395 gene

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
huntington disease	56.7	2	17897615 (1), 14625278 (1)

About this table

Export disorders and mutations for ZNF395 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/15 PubMed articles for ZNF395 gene, integrated from 7 sources (see all 15):
(articles sorted by number of sources associating them with ZNF395)

Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene. (PubMed id 14625278)^{1, 2, 3, 7} Tanaka K.... Ikeda J.-E. (2004)
A new cellular factor recognizes E2 binding sites of papillomaviruses which mediate transcriptional repression by E2. (PubMed id 11853404)^{1, 2, 7} Boeckle S.... Steger G. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma. (PubMed id 19018758)^{1, 7} Tsukahara T....Sato N. (2009)
Papillomavirus binding factor binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex. (PubMed id 17897615)^{1, 7} Sichtig N....Steger G. (2007)
Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor. (PubMed id 15289353)^{1, 7} Tsukahara T....Sato N. (2004)
Papillomavirus binding factor (PBF)-mediated inhibition of cell growth is regulated by 14-3-3beta. (PubMed id 17531190)^{1, 7} Sichtig N....Steger G. (2007)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 55893	HGNC: 18737	AceView: ZNF395andFBXO16	Ensembl:ENSG00000186918	euGenes: HUgn55893
ECgene: ZNF395	H-InvDB: ZNF395

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Intellectual Property for ZNF395 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

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Patent Information for ZNF395 gene:
Search GeneIP for patents involving ZNF395

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ZNF395		Antibodies for ZNF395
	Super-pooled esiRNAs for ZNF395		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ZNF395		microRNA Mimics for ZNF395
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
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	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
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	Antibodies		Cell Culture Products
	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
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	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF395
	SeqTarget long-range PCR primers for resequencing ZNF395
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF395
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF395

	GenScript Custom Purified and Recombinant Proteins Services for ZNF395		GenScript cDNA clones with any tag delivered in your preferred vector for ZNF395
	GenScript Custom Assay Services for ZNF395		GenScript Custom Superior Antibodies Services for ZNF395
	GenScript Custom overexpressing Cell Line Services for ZNF395		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in ZNF395 promoter
	Search Chromatin IP Primers for ZNF395
	RT² qPCR Primer Assay for ZNF395
	Search GNC Networks for ZNF395
	Assays for microRNAs that regulate ZNF395
	SABiosciences Custom PCR Arrays for ZNF395

Search Tocris compounds for ZNF395

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Antibodies for ZNF395
	Lysates for ZNF395

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

ELISAs and CLIAs for ZNF395

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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ZNF395 gene at Home site.

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ZNF395 Gene

protein-coding GIFtS: 48

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ZNF395 Gene

protein-coding GIFtS: 48

Aliases & Descriptionsfor ZNF395 gene

Summariesfor ZNF395 gene

Genomic Viewsfor ZNF395 gene

Proteinsfor ZNF395 gene

Protein Domains/Familiesfor ZNF395 gene

Gene Functionfor ZNF395 gene

Pathways & Interactionsfor ZNF395 gene

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Transcriptsfor ZNF395 gene

Expression for ZNF395 gene

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Specialized Databases showing ZNF395 gene

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Aliases &
Descriptions
for ZNF395 gene

Summaries
for ZNF395 gene

Genomic Views
for ZNF395 gene

Proteins
for ZNF395 gene

Protein Domains/
Families
for ZNF395 gene

Gene Function
for ZNF395 gene

Pathways & Interactions
for ZNF395 gene

Drugs & Compounds
for ZNF395 gene

Transcripts
for ZNF395 gene

Expression
for ZNF395 gene

Orthologs
for ZNF395 gene

Paralogs
for ZNF395 gene

Genomic Variants
for ZNF395 gene

Disorders & Mutations
for ZNF395 gene

Medical News
for ZNF395 gene

Publications
for ZNF395 gene

Intellectual Property
for ZNF395 gene

Products
for ZNF395 gene