Aliases &
Descriptions
for ZNF432 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 4321 2 | | KIAA07981 3 |
Export aliases for ZNF432 gene to outside databasesPrevious GC identifers: GC19M057172 GC19M057226 GC19M057190 GC19M057216 |
Summaries
for ZNF432 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF432 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF432 gene promoter:
Nkx3-1 Nkx3-1 v1 Nkx3-1 v2 Nkx3-1 v3 Nkx3-1 v4
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF432
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41ZNF432 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M052467: view genomic region
(about GC identifiers)
Start:
|
52,467,594 bp from pter |
End:
|
52,627,345 bp from pter |
Size:
|
159,752 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr19- 48,867,321-48,882,729 |
RefSeq DNA sequence:- NC_000019.9 NT_011109.16
|
Proteins
for ZNF432 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892 (See
protein sequence)Recommended Name: Zinc finger protein 432 Size: 652 amino acids; 74836 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA34518.2; Type=Erroneous initiation;Explore the universe of human proteins at neXtProt for ZNF432: NX_O94892
REFSEQ proteins: NP_055465.1
ENSEMBL proteins: ENSP00000243644 ENSP00000375672 ENSP00000365906 ENSP00000347019 ENSP00000375670 ENSP00000221315
Human Recombinant Proteins
5 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF432 for ontologies About GeneDecksing
Antibodies for ZNF432:
Assays for ZNF432: |
Protein
Domains/
Families
for ZNF432 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF432 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O94892ProtoNet protein and cluster: O94892 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 16 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Gene Function
for ZNF432 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Function: May be involved in transcriptional regulation
5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6): About this table
ZNF432 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF432 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF432
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF432
5 Interacting proteins for ZNF432 (ENSP000002436443) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0016481 | negative regulation of transcription |
-- | -- |
About this table
ZNF432 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF432 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF432
|
Transcripts
for ZNF432 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF432 gene: NM_014650.2 Additional cDNA sequence: AB018341.1 AK292827.1 BC002858.2 2 DOTS entries: DT.307847 DT.400726 24/73 AceView cDNA sequences (see all 73): AK131334 AK131409 AW002711 AX748176 BP367484 BQ961564 AA827512 F28968 BQ638587 BC002858 AA393349 NM_014650 BQ007073 AK093512 CK430746 AK129938 AI224599 CD625871 AB018341 CB107815 CD625875 CA849135 BU521429 BX503070
 highest scoring ESTs for ZNF432:AB018341 BC002858 BE410092 BE410115 AV707048 BG697381 BM772329 BM846597 CN361842 CN361843 Unigene Cluster for ZNF432: Zinc finger protein 432 Hs.655934 [show with all ESTs]Unigene Representative Sequence: AB018341
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF432 (see all 11)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF432
6 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000243644(uc002pyd.2) ENST00000391795 ENST00000376716(uc002pye.1 uc002pyf.1 uc002pyg.1 uc002pyh.1 uc010epi.1 uc010ydg.1)
ENST00000354939 ENST00000391793 ENST00000221315(uc002pyk.2)
|
Expression
for ZNF432 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF432 expression in normal and diseased human tissues
1 / 2 / 3 2 probe-sets matching ZNF432 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 219848_s_at2, 3
|
U133-A |
1 |
0.27 |
1.00 |
-- |
-- |
NM_014650 |
0.60 |
0.83 |
0.73 |
1 |
| 219848_s_at2
|
U133Plus2 |
1 |
0.27 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.655934
SABiosciences Custom PCR Arrays for ZNF432
|
Orthologs
for ZNF432 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF432 gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
ZNF4321 |
-- |
zinc finger protein 432 |
99.54(n)
99.54(a) |
748939 XM_001174404.1 XP_001174404.1 |
About this table Species with no ortholog for ZNF432
ENSEMBL Gene Tree for ZNF432 (if available) |
Paralogs
for ZNF432 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF432 gene
- LOC1002874292 ZNF6052 ZNF842 ZNF6302 ZNF102 ZNF6142 ENSG000002296312 ENSG000002365752
- ZNF5682 ZNF262 ZNF6132 ZNF6492 ZNF3002 ZNF5692
ZNF432 for paralogs About GeneDecksing
Pseudogenes
- 1 related pseudogene
|
Genomic Variants
for ZNF432 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 19 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF432 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for ZNF432
4 CNVs: 8875 3195 34482 53103 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF432 |
|
Disorders & Mutations
for ZNF432 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZNF432 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF432 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for ZNF432 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF432)- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (1998)
- Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PubMed id 16777052)1, 2, 7 Zhan X. and Desiderio D.M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF432 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF432 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF432 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF432 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF432 gene:
Search GeneIP for patents involving ZNF432
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF432 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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