Aliases &
Descriptions
for ZNF438 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 4381 2 | | OTTHUMP000000194012 | | bA330O11.11 2 | | OTTHUMP000001790842 | | OTTHUMP000000194022 | | FLJ327612 | | MGC1266712 | | |
Export aliases for ZNF438 gene to outside databasesPrevious GC identifer: GC10M031174 |
Summaries
for ZNF438 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN438_HUMAN, Q7Z4V0Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF438 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF438 gene promoter:
Bach1 AP-1 c-Fos c-Jun Fra-1 JunB JunD YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF438
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF438  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p11.23 Ensembl cytogenetic band: 10p11.22 HGNC cytogenetic band: 10p11.23ZNF438 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M030852: view genomic region
(about GC identifiers)
Start:
|
30,852,425 bp from pter |
End:
|
31,039,740 bp from pter |
Size:
|
187,316 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr10- 31,133,563-31,320,866 |
RefSeq DNA sequence:- NC_000010.10 NT_008705.16
|
Proteins
for ZNF438 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN438_HUMAN, Q7Z4V0 (See
protein sequence)Recommended Name: Zinc finger protein 438 Size: 828 amino acids; 91836 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A2A3J4 A8K9L5 Q5T426 Q658Q4 Q6ZN65Alternative splicing: 3 isoforms: Q7Z4V0-1 Q7Z4V0-2 Q7Z4V0-3 Explore the universe of human proteins at neXtProt for ZNF438: NX_Q7Z4V0
REFSEQ proteins (7 alternative transcripts):
NP_001137238.1 NP_001137239.1 NP_001137240.1 NP_001137241.1 NP_001137242.1 NP_001137243.1 NP_877432.1
ENSEMBL proteins: ENSP00000387546 ENSP00000413060 ENSP00000406934 ENSP00000333571 ENSP00000412363 ENSP00000410898 ENSP00000416214 ENSP00000364460 ENSP00000354663
Human Recombinant Proteins
3 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF438 for ontologies About GeneDecksing
Antibodies for ZNF438:
Assays for ZNF438: |
Protein
Domains/
Families
for ZNF438 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF438 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7Z4V0ProtoNet protein and cluster: Q7Z4V0 UniProtKB/Swiss-Prot: ZN438_HUMAN, Q7Z4V0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 4 C2H2-type zinc fingers |
Gene Function
for ZNF438 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN438_HUMAN, Q7Z4V0Function: May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF438 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF438 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF438
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF438
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | | GO:0045449 | regulation of transcription |
IEA | -- |
About this table
ZNF438 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF438 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF438
|
Transcripts
for ZNF438 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF438 gene (7 alternative transcripts): NM_001143766.1 NM_001143767.1 NM_001143768.1 NM_001143769.1 NM_001143770.1 NM_001143771.1 NM_182755.2 Additional cDNA sequence: AF428258.1 AF440405.1 AK057323.1 AK131357.1 AK292730.1 AK294253.1 AL833056.1 BC101622.1 BC104669.1 BC104757.1 BC143462.1 BC143464.1 DQ356011.1 DQ356012.1 13 DOTS entries: DT.99931060 DT.406709 DT.121255765 DT.91856762 DT.100745795 DT.102827920 DT.121255762 DT.100672639 DT.40242305 DT.121255721 DT.40204888 DT.95253135 DT.91917746 24/53 AceView cDNA sequences (see all 53): CA309854 CA309823 AA330854 CD358112 BQ004646 AI537321 BG614813 AK131357 NM_182755 AW007325 CA309853 AI056759 BM674747 AI563915 BM717381 AI369618 BX093705 AW293842 AI198234 BI861876 AF428258 AI766955 AK057323 BU159443
 highest scoring ESTs for ZNF438:AW007325 AF428258 AK057323 AK131357 BU159443 AA258045 AA259136 AA330854 AA490886 AF440405 Unigene Cluster for ZNF438: Zinc finger protein 438 Hs.660642 [show with all ESTs]Unigene Representative Sequence: NM_001143769
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF438
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | · | 11c |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF438
9 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000413025 ENST00000452305(uc010qdy.1 uc010qdz.1 uc001ivo.3 uc009xlg.2 uc001ivp.3 uc010qea.1 uc010qeb.1 uc010qec.1)
ENST00000436087 ENST00000331737 ENST00000442986 ENST00000444692 ENST00000430896
ENST00000375311 ENST00000361310(uc001ivn.2)
|
Expression
for ZNF438 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF438 expression in normal and diseased human tissues
1 / 2 / 3 7 probe-sets matching ZNF438 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 43398_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
0.94 |
1.18 |
AW007325 |
0.80 |
1.00 |
0.91 |
1 |
| 91927_at2, 3
|
U95-D |
1 |
1.00 |
1.00 |
0.69 |
0.77 |
AI563915 |
0.60 |
1.00 |
0.82 |
1 |
| 49935_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
0.94 |
1.06 |
AI886666 |
0.40 |
1.00 |
0.76 |
1 |
| 244752_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AI563915 |
0.60 |
1.00 |
0.82 |
1 |
| 229743_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AI886666 |
0.40 |
1.00 |
0.76 |
1 |
| 244752_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 229743_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF438 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.660642
SABiosciences Custom PCR Arrays for ZNF438
|
Orthologs
for ZNF438 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF438 gene from 5/7 species (see all 7)
About this table Species with no ortholog for ZNF438
ENSEMBL Gene Tree for ZNF438 (if available) |
Paralogs
for ZNF438 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for ZNF438 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 10 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF438 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for ZNF438
5 CNVs: 34871 65632 58442 85168 58441
5 Indels: 10671 10668 75165 10669 10670 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF438 |
|
Disorders & Mutations
for ZNF438 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF438 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF438 (2 documents)
Export disorders and mutations for ZNF438 gene to outside databases
|
Medical News
for ZNF438 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF438 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/11 PubMed articles for ZNF438 gene, integrated from 7 sources (see all 11):
(articles sorted by number of sources associating them with ZNF438)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity. (PubMed id 17669267)1 Zhong Z....Yu L. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF438 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF438 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF438 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF438 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF438 gene:
Search GeneIP for patents involving ZNF438
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF438 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for ZNF438 |
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