Aliases &
Descriptions
for ZNF468 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 4681 2 | | DKFZp781B14742 | | DKFZp781N071082 | | zinc finger protein ZNF4682 |
Export aliases for ZNF468 gene to outside databasesPrevious GC identifers: GC19M058034 GC19M053341 |
Summaries
for ZNF468 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN468_HUMAN, Q5VIY5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF468 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF468 gene promoter:
POU2F1 ATF6 STAT5B STAT5A AREB6 MRF-2 STAT3 XBP-1 POU2F1 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF468
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41ZNF468 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M049669: view genomic region
(about GC identifiers)
Start:
|
49,669,384 bp from pter |
End:
|
49,688,491 bp from pter |
Size:
|
19,108 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr19- 53,341,786-53,360,902 |
|
Proteins
for ZNF468 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN468_HUMAN, Q5VIY5 (See
protein sequence)Recommended Name: Zinc finger protein 468 Size: 522 amino acids; 60573 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A8MV20 Q5CZB8 Q5VIY4 Q68DI7Alternative splicing: 2 isoforms: Q5VIY5-1 Q5VIY5-2 Explore the universe of human proteins at neXtProt for ZNF468: NX_Q5VIY5
REFSEQ proteins (2 alternative transcripts):
NP_001008801.1 NP_954583.1
ENSEMBL proteins: ENSP00000243639 ENSP00000379690
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF468 for ontologies About GeneDecksing
Antibodies for ZNF468:
Assays for ZNF468: |
Protein
Domains/
Families
for ZNF468 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF468 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5VIY5ProtoNet protein and cluster: Q5VIY5 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN468_HUMAN, Q5VIY5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Gene Function
for ZNF468 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN468_HUMAN, Q5VIY5Function: May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF468 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF468 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF468
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF468
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
About this table
ZNF468 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF468 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF468
|
Transcripts
for ZNF468 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF468 gene (2 alternative transcripts): NM_001008801.1 NM_199132.1 24/47 AceView cDNA sequences (see all 47): BC008480 AK025501 R78627 CA394881 BF438910 AI872737 BX955314 BX106193 BX952497 BM828200 BC037409 H04753 CR749381 AW862251 AU136526 BX509654 BM755225 BX497090 BG056504 CF593393 BI334272 AW664160 CA392690 BG403135
 highest scoring ESTs for ZNF468:AA354849 AA984824 AK023558 AK025501 AV724657 AW862251 AY442330 AY442331 BC008480 BC037409
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000243639(uc002qae.2 uc002qaf.2) ENST00000396409
|
Expression
for ZNF468 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF468 expression in normal and diseased human tissues
1 / 2 / 3 2 probe-sets matching ZNF468 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 214751_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
BE541042 |
0.20 |
1.00 |
0.72 |
1 |
| 214751_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TCATCTACAA
UniProtKB/Swiss-Prot: ZN468_HUMAN, Q5VIY5Tissue specificity: Isoform 1 and isoform 2 are highly expressed in placenta, pancreas, and small intestine. Lowerexpression in colon, ovary, testis, prostate, thymus, spleen, kidney, and liver. No expression detected in heart andbrain
SABiosciences Custom PCR Arrays for ZNF468
|
Orthologs
for ZNF468 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for ZNF468 (if available) |
Paralogs
for ZNF468 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF468 gene
- ZNF6162 ZNF5342 ZNF1602 ZNF6652 ZNF8802 ZNF7662 ZNF8602 ZNF3202
- ZNF5252 ZNF4152 ZNF6002 ZNF5282 ZNF3212 ZNF282 ZNF6112 ZNF6772
- ZNF3472 ZNF8082 ENSG000002138012 ZNF832 ZNF8452 ZNF6102 ZNF8162 ZNF7012
- ZNF7652 ZNF8882 ZNF4802 ZNF8132
ZNF468 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF468 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 19 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF468 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 17 variations for ZNF468
15/17 CNVs (see all 17): 35673 9809 38938 9807 3196 50201 59602 58888 78256 53448 37637 30916 9808 67596 37596 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF468 |
|
Disorders & Mutations
for ZNF468 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZNF468 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF468 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for ZNF468 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF468)- A novel zinc finger gene ZNF468 with two co-expressional splice variants, ZNF468.1 and ZNF468.2. (PubMed id 16144304)1, 2, 3, 7 Sun L....Mao Y. (2005)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF468 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF468 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF468 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF468 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF468 gene:
Search GeneIP for patents involving ZNF468
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF468 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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