Aliases &
Descriptions
for ZNF558 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 5581 2 | | FLJ309321 2 |
Export aliases for ZNF558 gene to outside databasesPrevious GC identifers: GC19M008782 GC19M008784 GC19M008920 |
Summaries
for ZNF558 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN558_HUMAN, Q96NG5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF558 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF558 gene promoter:
POU2F1 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 FOXL1 LCR-F1 p53 TBP RORalpha1 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF558
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF558  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC chromosome: 19ZNF558 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M008497: view genomic region
(about GC identifiers)
Start:
|
8,497,798 bp from pter |
End:
|
8,510,979 bp from pter |
Size:
|
13,182 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr19- 8,920,382-8,942,935 |
RefSeq DNA sequence:- NC_000019.9 NT_011295.11
|
Proteins
for ZNF558 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN558_HUMAN, Q96NG5 (See
protein sequence)Recommended Name: Zinc finger protein 558 Size: 402 amino acids; 45755 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A8K5F0Explore the universe of human proteins at neXtProt for ZNF558: NX_Q96NG5
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_653294.1
ENSEMBL proteins: ENSP00000301475 ENSP00000410703
Human Recombinant Proteins
3 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF558 for ontologies About GeneDecksing
Antibodies for ZNF558:
Assays for ZNF558: |
Protein
Domains/
Families
for ZNF558 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF558 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96NG5ProtoNet protein and cluster: Q96NG5 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN558_HUMAN, Q96NG5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 9 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Gene Function
for ZNF558 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN558_HUMAN, Q96NG5Function: May be involved in transcriptional regulation
5 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF558 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF558 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF558
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF558
1 Interacting protein for ZNF558 (Q96NG51) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
About this table
ZNF558 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF558 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF558
|
Transcripts
for ZNF558 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF558 gene: NM_144693.1 Additional cDNA sequence: AK055494.1 AK291265.1 AK301664.1 AK307200.1 BC064356.1 6 DOTS entries: DT.97864487 DT.40130364 DT.92023390 DT.100742589 DT.121451346 DT.91973857 24/70 AceView cDNA sequences (see all 70): AI373505 AW440452 N74538 BP379004 BM677021 AI813807 BM975824 AW440433 BQ575866 AI693067 CK003200 BC064356 BX505367 AA366475 BI711389 BM126757 AA453272 CB306785 CK818802 AW966078 BG611439 BM825546 AW172849 AK055494
 highest scoring ESTs for ZNF558:AK055494 BC064356 BI255074 W02932 AA150725 AA150784 AA366475 AA402853 AA453272 AA453372 Unigene Cluster for ZNF558: Zinc finger protein 558 Hs.659797 [show with all ESTs]Unigene Representative Sequence: AK055494
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000301475(uc010xkh.1 uc002mkn.1 uc010dwg.1) ENST00000444186
|
Expression
for ZNF558 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF558 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching ZNF558 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 56823_at2, 3
|
U95-B |
1 |
0.50 |
1.00 |
1.00 |
1.00 |
W02932 |
0.80 |
1.00 |
0.91 |
1 |
| 227810_at2, 3
|
U133-B |
1 |
0.27 |
1.00 |
-- |
-- |
AW119060 |
0.60 |
1.00 |
0.82 |
1 |
| 227810_at2
|
U133Plus2 |
1 |
0.27 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF558 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TGACAGCTCA
SOURCE GeneReport for Unigene cluster: Hs.659797
SABiosciences Custom PCR Arrays for ZNF558
|
Orthologs
for ZNF558 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF558 gene from 2 species
About this table Species with no ortholog for ZNF558
ENSEMBL Gene Tree for ZNF558 (if available) |
Paralogs
for ZNF558 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF558 gene
- ZNF1772 ZNF3332 ZNF5572 ZNF3172 ZNF8912
ZNF558 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF558 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 19 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF558 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for ZNF558
7 CNVs: 35695 5083 0509 0220 5081 4067 5082 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF558 |
|
Disorders & Mutations
for ZNF558 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for ZNF558 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF558 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
4 PubMed articles for ZNF558 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF558)- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A protein interaction framework for human mRNA degradation. (PubMed id 15231747)1 Lehner B. and Sanderson C.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF558 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF558 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF558 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF558 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF558 gene:
Search GeneIP for patents involving ZNF558
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF558 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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