Aliases &
Descriptions
for ZNF642 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 6421 2 | | FLJ160301 2 | | Zfp691 2 | | RP11-656D10.22 |
Export aliases for ZNF642 gene to outside databasesPrevious GC identifers: GC00U920639 GC01P040612 GC01P040715 GC01P040942 |
Summaries
for ZNF642 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN642_HUMAN, Q49AA0Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF642 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF642 gene promoter:
Nkx6-1 MRF-2 RORalpha1 NF-E2 NF-E2 p45 SRF E4BP4 POU2F1 FOXO3a FOXO3b
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF642
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF642  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p34.2 Ensembl cytogenetic band: 1p34.2 HGNC cytogenetic band: 1p34.2ZNF642 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P039063: view genomic region
(about GC identifiers)
Start:
|
39,061,578 bp from pter |
End:
|
39,080,071 bp from pter |
Size:
|
18,494 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr1+ 40,942,887-40,962,015 |
RefSeq DNA sequence:- NC_000001.10 NT_032977.9
|
Proteins
for ZNF642 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZN642_HUMAN, Q49AA0 (See
protein sequence)Recommended Name: Zinc finger protein 642 Size: 526 amino acids; 61181 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAC85492.1; Type=Erroneous termination; Positions=506; Note=Translated as Tyr;
Secondary accessions: Q5SWM5 Q6ZWK8Explore the universe of human proteins at neXtProt for ZNF642: NX_Q49AA0
REFSEQ proteins: NP_940896.2
ENSEMBL proteins: ENSP00000361790 ENSP00000361791
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF642 for ontologies About GeneDecksing
Antibodies for ZNF642:
Assays for ZNF642: |
Protein
Domains/
Families
for ZNF642 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF642 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q49AA0ProtoNet protein and cluster: Q49AA0 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN642_HUMAN, Q49AA0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 9 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Gene Function
for ZNF642 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZN642_HUMAN, Q49AA0Function: May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF642 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF642 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF642
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF642
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
About this table
ZNF642 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF642 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF642
|
Transcripts
for ZNF642 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF642 gene: NM_198494.2 Additional cDNA sequence: AK122618.1 BC041873.1 BC078148.1 BC144174.1 5 DOTS entries: DT.97776924 DT.40316648 DT.99993978 DT.102821018 DT.97799519 18 AceView cDNA sequences: BM677727 AK122618 NM_198494 BC078148 BU164774 BG251945 CB241064 AA948585 BM725287 BC041873 BM987592 AI653297 BF965225 AJ710572 AA477496 BI463617 AA479865 AI925094
 highest scoring ESTs for ZNF642:AI653297 AK122618 CB241064 AA479865 AA948585 AI925094 AJ710572 BC041873 BF965225 BG251945 Unigene Cluster for ZNF642: Zinc finger protein 642 Hs.434385 [show with all ESTs]Unigene Representative Sequence: BC041873
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF642
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF642
3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372705 ENST00000482712 ENST00000372706(uc001cfo.2 uc009vwb.2 uc010ojk.1)
|
Expression
for ZNF642 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF642 expression in normal and diseased human tissues
1 / 2 / 3 2 probe-sets matching ZNF642 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 60688_at2, 3
|
U95-C |
1 |
0.81 |
1.00 |
1.00 |
1.00 |
AI653297 |
0.80 |
1.00 |
0.91 |
1 |
| 1569107_s_at2
|
U133Plus2 |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF642 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GGTAAAAAAA
SOURCE GeneReport for Unigene cluster: Hs.434385
SABiosciences Custom PCR Arrays for ZNF642
|
Orthologs
for ZNF642 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF642 gene from 3 species
About this table Species with no ortholog for ZNF642
ENSEMBL Gene Tree for ZNF642 (if available) |
Paralogs
for ZNF642 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF642 gene
- ZNF5702 ZNF6432 ZNF1812 ZFP282 ZNF4712 ZNF7132 ZNF3022 ZNF342
- ZNF5832 ZNF5272 ZNF82 ZNF4702
ZNF642 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF642 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 1 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF642 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF642
1 CNV: 97338 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF642 |
|
Disorders & Mutations
for ZNF642 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF642 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF642 (1 document)
Export disorders and mutations for ZNF642 gene to outside databases
|
Medical News
for ZNF642 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF642 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
9 PubMed articles for ZNF642 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF642)- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Positional cloning of zinc finger domain transcriptio n factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL. (PubMed id 19578398)1 Scherneck S....Joost H.G. (2009)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for ZNF642 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF642 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF642 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF642 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF642 gene:
Search GeneIP for patents involving ZNF642
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF642 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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