Aliases &
Descriptions
for ZNF76 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger protein 76 (expressed in testis)1 2 | | Zinc finger protein 5232 3 | | ZNF5231 2 3 | | OTTHUMP000002155212 | | D6S229E2 3 5 | | zinc finger protein 762 | | Zfp5231 2 | | |
Export aliases for ZNF76 gene to outside databasesPrevious GC identifers: GC06P035229 GC06P035274 GC06P035335 |
Summaries
for ZNF76 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZNF76_HUMAN, P36508Function: May be involved in transcriptional regulation
Gene Wiki entry for ZNF76 |
Genomic Views
for ZNF76 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF76 gene promoter:
p300 TBP TFIID Arnt AhR p53 Max1 c-Myc SRY C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF76
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF76  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.3-p21.2 Ensembl cytogenetic band: 6p21.31 HGNC cytogenetic band: 6p21.3-p21.2ZNF76 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P034948: view genomic region
(about GC identifiers)
Start:
|
34,948,737 bp from pter |
End:
|
34,984,978 bp from pter |
Size:
|
36,242 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr6+ 35,226,686-35,263,762 |
RefSeq DNA sequence:- NC_000006.11 NT_007592.15
|
Proteins
for ZNF76 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZNF76_HUMAN, P36508 (See
protein sequence)Recommended Name: Zinc finger protein 76 Size: 570 amino acids; 61831 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q9BQB2Alternative splicing: 2 isoforms: P36508-1 P36508-2 Explore the universe of human proteins at neXtProt for ZNF76: NX_P36508
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_003418.2
ENSEMBL proteins: ENSP00000410765 ENSP00000416550 ENSP00000229405 ENSP00000418749 ENSP00000344097 ENSP00000392243 ENSP00000419106 ENSP00000363064
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
ZNF76 for ontologies About GeneDecksing
Antibodies for ZNF76:
Assays for ZNF76: |
Protein
Domains/
Families
for ZNF76 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF76 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P36508ProtoNet protein and cluster: P36508 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF76_HUMAN, P36508Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 7 C2H2-type zinc fingers |
Gene Function
for ZNF76 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZNF76_HUMAN, P36508Function: May be involved in transcriptional regulation
Genatlas biochemistry entry for ZNF76:zinc finger protein 76 (C2H2 type,Kruppel-like),transactivator protein,DNA protein related to Xenopus laevis STAF andZNF1434 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZNF76 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF76 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZNF76
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF76
1 Interacting protein for ZNF76 (P365082) via UniProtKB, MINT, and/or STRINGAbout this table
3 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 9705341 | | GO:0006359 | regulation of transcription from RNA polymerase III promoter |
TAS | 9705341 | | GO:0045449 | regulation of transcription |
IEA | -- |
About this table
ZNF76 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF76 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZNF76
|
Transcripts
for ZNF76 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZNF76 gene: NM_003427.3 Additional cDNA sequence: AK294605.1 AK295276.1 AK302903.1 AK304626.1 AK310877.1 BC000133.2 BC002549.2 BT007316.1 CR614742.1 M91592.1 12 DOTS entries: DT.215030 DT.100818833 DT.100818831 DT.91752500 DT.40316328 DT.446245 DT.121386804 DT.97822063 DT.101956077 DT.91755432 DT.95261276 DT.95278275 24/189 AceView cDNA sequences (see all 189): BM712364 BM810280 BM854905 CR614742 AA335667 BM743659 BQ059510 BU741686 BI870145 BM790806 BM724427 BQ216715 BM854991 BM928406 BQ007602 BQ777334 AA486210 BE390417 BX095537 BF975307 BT007316 BQ000589 CA412475 BG469612
 highest scoring ESTs for ZNF76:M91592 AA047454 AA047511 AA335343 AA335667 AA349385 AA350179 AA486210 AA575867 AA583667 Unigene Cluster for ZNF76: Zinc finger protein 76 (expressed in testis) Hs.388024 [show with all ESTs]Unigene Representative Sequence: NM_003427
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF76 (see all 10)
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14 | ^ | 15 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | |
| SP3: | | | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ZNF76
14 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000417184 ENST00000448999 ENST00000479226 ENST00000229405 ENST00000498555
ENST00000482946 ENST00000491400(uc011dsx.1) ENST00000460229 ENST00000486891(uc011dsy.1)
ENST00000339411 ENST00000440666 ENST00000469195(uc011dsz.1) ENST00000484932
ENST00000373953(uc003oki.1 uc003okj.1)
|
Expression
for ZNF76 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZNF76 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching ZNF76 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 35225_at2, 3
|
U95-A |
1 |
1.00 |
1.00 |
1.00 |
1.00 |
M91592 |
1.00 |
1.00 |
1.00 |
1 |
| 207494_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_003427 |
0.60 |
1.00 |
0.82 |
1 |
| 207494_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZNF76 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GATGAATGAG
SOURCE GeneReport for Unigene cluster: Hs.388024
Expression variation in blood from EXPOLDB for ZNF76 UniProtKB/Swiss-Prot: ZNF76_HUMAN, P36508Tissue specificity: Testis
SABiosciences Custom PCR Arrays for ZNF76
|
Orthologs
for ZNF76 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZNF76 gene from 5/7 species (see all 7)
About this table Species with no ortholog for ZNF76
ENSEMBL Gene Tree for ZNF76 (if available) |
Paralogs
for ZNF76 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZNF76 gene
- YY22 MTF12 ZFP422 ZNF1432 ZNF4102 YY12
ZNF76 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF76 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 6 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZNF76 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF76
1 CNV: 3606 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZNF76 |
|
Disorders & Mutations
for ZNF76 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF76 for disorders About GeneDecksing
OMIM: 194549
Human Genome Epidemiology (HuGE) Navigator: ZNF76 (4 documents)
Export disorders and mutations for ZNF76 gene to outside databases
|
Medical News
for ZNF76 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZNF76 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/13 PubMed articles for ZNF76 gene, integrated from 7 sources (see all 13):
(articles sorted by number of sources associating them with ZNF76)- A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11. (PubMed id 1427894)1, 2, 3 Ragoussis J.... Trowsdale J. (1992)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation. (PubMed id 15280358)1, 7 Zheng G. and Yang Y.C. (2004)
- The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)1 Zhao J....Grant S.F. (2010)
- Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1 Han S....Kang D. (2010)
- Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1 Rajaraman P....Inskip P.D. (2010)
- Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (2009)
- Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1 Gudbjartsson D.F....Stefansson K. (2008)
- Acetylation and alternative splicing regulate ZNF76-mediated transcription. (PubMed id 16337145)1 Zheng G. and Yang Y.C. (2006)
- Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP. (PubMed id 16522640)1 Prigge J.R. and Schmidt E.E. (2006)
|
External Searches for ZNF76 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF76 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF76 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF76 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF76 gene:
Search GeneIP for patents involving ZNF76
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF76 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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 |  |  |  | |
| |  | Search Tocris compounds for ZNF76 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for ZNF76 |
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