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ZNF790 Gene

protein-coding   GIFtS: 38

GC19M033777
zinc finger protein 790
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
zinc finger protein 7901 2
FLJ203501 2
MGC621001 2

External Ids:    HGNC: 331141   Entrez Gene: 3885362   Ensembl: ENSG000001978637   UniProtKB: Q6PG373   

Export aliases for ZNF790 gene to outside databases

Previous GC identifers: GC19M041997 GC19M037308


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN790_HUMAN, Q6PG37
Function: May be involved in transcriptional regulation


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF790
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ZNF790

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF790 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.12

ZNF790 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF790 gene location

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M033777:  view genomic region     (about GC identifiers)

Start:
33,777,136 bp from pter
End:
33,797,808 bp from pter
Size:
20,673 bases
Orientation:
minus strand

1 alternative location:
Chr19- 37,308,336-37,329,284     
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ZN790_HUMAN, Q6PG37 (See protein sequence)
Recommended Name: Zinc finger protein 790  
Size: 636 amino acids; 74571 Da
Subcellular location: Nucleus (Potential)

Explore the universe of human proteins at neXtProt for ZNF790: NX_Q6PG37 

REFSEQ proteins: NP_996777.2  

ENSEMBL proteins: 
ENSP00000349161 


Human Recombinant Proteins 
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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005622 intracellular IEA--
GO:0005634 nucleus IEA--
About this table

ZNF790 for ontologies           About GeneDecksing



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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF790 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR001909 Krueppel-associated_box
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q6PG37

ProtoNet protein and cluster: Q6PG37

1 Blocks protein family: IPB001909 KRAB box

UniProtKB/Swiss-Prot: ZN790_HUMAN, Q6PG37
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 13 C2H2-type zinc fingers
Similarity: Contains 1 KRAB domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ZN790_HUMAN, Q6PG37
Function: May be involved in transcriptional regulation

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
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Sigma-Aldrich esiRNA and siRNA for ZNF790
Sigma-Aldrich shRNA for ZNF790
OriGene 29mer shRNA kits in GFP-retroviral vector: ZNF790
OriGene shRNA RFP: ZNF790
OriGene basic RS shRNA: ZNF790
OriGene siRNA: ZNF790
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF790 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF790 
Search SABiosciences for Assays for microRNAs that regulate ZNF790

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ZNF790
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF790
OriGene untagged cDNA clones in CMV expression vector: ZNF790
OriGene 3'-UTR clone: ZNF790 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ZNF790 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for ZNF790 

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003676 nucleic acid binding ----
GO:0003677 DNA binding IEA--
GO:0008270 zinc ion binding IEA--
GO:0046872 metal ion binding IEA--
About this table

ZNF790 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for ZNF790 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF790

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006355 regulation of transcription, DNA-dependent IEA--
About this table

ZNF790 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF790


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for ZNF790
Sigma-Aldrich shRNA for ZNF790
OriGene 29mer shRNA kits in GFP-retroviral vector: ZNF790
OriGene shRNA RFP: ZNF790
OriGene basic RS shRNA: ZNF790
OriGene siRNA: ZNF790
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF790 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF790 
Search SABiosciences for Assays for microRNAs that regulate ZNF790
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ZNF790
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF790
OriGene untagged cDNA clones in CMV expression vector: ZNF790
OriGene 3'-UTR Clone: ZNF790 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ZNF790 
Primers: OriGene genome-wide validated SYBR primer pairs: ZNF790
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ZNF790: PPH15839A

REFSEQ mRNAs for ZNF790 gene: 

NM_206894.2  

Additional cDNA sequence: AK297474.1 

6 DOTS entries:

DT.91969228  DT.95099758  DT.86847548  DT.86842455  DT.70100310  DT.121503605 

24/32 AceView cDNA sequences (see all 32):

BI714811 BM473790 BU069053 CA773758 BI715382 AI873476 BE714172 AI183815 
BC057245 BM803615 NM_206894 AA142993 AA151098 BM852743 AA151111 CB243330 
AW373744 BU941082 AI808437 BX496436 CD515963 AI917553 AI066655 AI692841 

highest scoring ESTs for ZNF790:

BU941082 AA056061 AA143010 AA151098 AA151111 AA488741 AI183815 AI457947 AI692841 AI808437 

Unigene Cluster for ZNF790:

Zinc finger protein 790
Hs.282067  [show with all ESTs]
Unigene Representative Sequence: NM_206894


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000356725(uc002oew.2)

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ZNF790 expression in normal and diseased human tissues

1  / 2  / 3

2 probe-sets matching ZNF790 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
73212_at2, 3 U95-D 1 0.69 1.00 1.00 1.00 AI183815 0.40 1.00 0.76 1
78301_r_at2, 3 U95-E 1 0.56 1.00 0.16 0.20 AA143010 0.40 1.00 0.76 1
About this table

ZNF790 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
ZNF790 gene expression
ZNF790 gene electronic northern expression
ZNF790 gene sage expression
About these images

CGAP SAGE TAG: TCTTGTTTCA

SOURCE GeneReport for Unigene cluster: Hs.282067
Primers: OriGene genome-wide validated SYBR primer pairs: ZNF790
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ZNF790: PPH15839A
    SABiosciences Custom PCR Arrays for ZNF790 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ZNF790 gene from 3 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
ZNF7901   -- zinc finger protein 790 89.52(n)
84.36(a)
484548  XM_541662.1  XP_541662.1 
chimpanzee
(Pan troglodytes)
ZNF7901   -- zinc finger protein 790 99.42(n)
99.53(a)
455983  XM_001164063.1  XP_001164063.1 
mouse
(Mus musculus)
Zfp7901 , 5 7 (17.26 cM)5
zinc finger protein 7901, 5 64.71(n)1
52.28(a)1
2330561  NM_146185.11  NP_666297.11 
 AA1823425  AI4501545  (see all 14)
About this table        Species with no ortholog for ZNF790

ENSEMBL Gene Tree for ZNF790 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for ZNF790 gene
ZNF5712  ZNF8502  ZNF1402  ZNF3832  ZNF4612  ZNF5822  ZNF3452  ZNF8292  
ZNF6072  ZNF5732  ZNF5662  ZNF5652  ENSG000002048792  

ZNF790 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF790
     2 CNVs: 10553 9306
QIAGEN SeqTarget long-range PCR primers for resequencing ZNF790 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

4 PubMed articles for ZNF790 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF790)
  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 388536 HGNC: 33114 AceView: MGC62100 Ensembl:ENSG00000197863 euGenes: HUgn388536
ECgene: ZNF790 H-InvDB: ZNF790

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for ZNF790 gene:
Search GeneIP for patents involving ZNF790

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
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 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF790
 SeqTarget long-range PCR primers for resequencing ZNF790
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF790
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF790
 GenScript Custom Purified and Recombinant Proteins Services for ZNF790 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ZNF790
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