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ZNF835 Gene

protein-coding   GIFtS: 37

GC19M053484
zinc finger protein 835
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
zinc finger protein 8351 2
BC37295_31 2

External Ids:    HGNC: 343321   Entrez Gene: 904852   Ensembl: ENSG000001279037   UniProtKB: Q9Y2P03   

Export aliases for ZNF835 gene to outside databases

Previous GC identifers: GC19M061868 GC19M057174


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN835_HUMAN, Q9Y2P0
Function: May be involved in transcriptional regulation


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF835
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ZNF835

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF835 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.43   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

ZNF835 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF835 gene location

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M053484:  view genomic region     (about GC identifiers)

Start:
53,484,593 bp from pter
End:
53,493,886 bp from pter
Size:
9,294 bases
Orientation:
minus strand

1 alternative location:
Chr19- 57,174,635-57,176,830     
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ZN835_HUMAN, Q9Y2P0 (See protein sequence)
Recommended Name: Zinc finger protein 835  
Size: 559 amino acids; 62084 Da
Subcellular location: Nucleus (Probable)

Explore the universe of human proteins at neXtProt for ZNF835: NX_Q9Y2P0 

REFSEQ proteins: NP_001005850.1  

ENSEMBL proteins: 
ENSP00000341756 


Human Recombinant Proteins 
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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005622 intracellular IEA--
GO:0005634 nucleus IEA--
About this table

ZNF835 for ontologies           About GeneDecksing



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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF835 for domains           About GeneDecksing

3 InterPro domains/families:
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q9Y2P0

ProtoNet protein and cluster: Q9Y2P0

1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

UniProtKB/Swiss-Prot: ZN835_HUMAN, Q9Y2P0
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 14 C2H2-type zinc fingers


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ZN835_HUMAN, Q9Y2P0
Function: May be involved in transcriptional regulation

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
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Sigma-Aldrich siRNA for ZNF835
Sigma-Aldrich shRNA for ZNF835
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZNF835
OriGene shRNA RFP (see all 2): ZNF835
OriGene basic RS shRNA (see all 2): ZNF835
OriGene siRNA (see all 2): ZNF835
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF835 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF835 
Search SABiosciences for Assays for microRNAs that regulate ZNF835

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ZNF835
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF835
OriGene untagged cDNA clones in CMV expression vector: ZNF835
Browse 3'-UTR reporter clones for miRNA target validation 
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Cell
Lines:
  
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3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003677 DNA binding IEA--
GO:0008270 zinc ion binding IEA--
GO:0046872 metal ion binding IEA--
About this table

ZNF835 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for ZNF835 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF835

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0045449 regulation of transcription IEA--
About this table

ZNF835 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF835


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for ZNF835
Sigma-Aldrich shRNA for ZNF835
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): ZNF835
OriGene shRNA RFP (see all 2): ZNF835
OriGene basic RS shRNA (see all 2): ZNF835
OriGene siRNA (see all 2): ZNF835
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF835 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF835 
Search SABiosciences for Assays for microRNAs that regulate ZNF835
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ZNF835
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZNF835
OriGene untagged cDNA clones in CMV expression vector: ZNF835
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: ZNF835 
Primers: OriGene genome-wide validated SYBR primer pairs: ZNF835
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ZNF835: PPH22277A

REFSEQ mRNAs for ZNF835 gene: 

NM_001005850.1  

Additional cDNA sequence: 

AK023017.1 AK299565.1 

4 DOTS entries:

DT.121432399  DT.92018153  DT.121499281  DT.212023 

3 AceView cDNA sequences:

AK023017 AU151540 AU129418 

Unigene Cluster for ZNF835:

Zinc finger protein 835
Hs.458438  [show with all ESTs]
Unigene Representative Sequence: AK023017


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000342088(uc010ygn.1 uc010ygo.1)

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ZNF835 expression in normal and diseased human tissues

1  / 2

2 probe-sets matching ZNF835 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
215826_x_at2 U133-A 5 0.55 0.79 -- -- -- -- -- -- --
215826_x_at2 U133Plus2 5 0.55 0.79 -- -- -- -- -- -- --
About this table
Data from Genenote  (Publications) and GNF BioGPS
    About these images
ZNF835 gene expression
ZNF835 gene electronic northern expression
ZNF835 gene sage expression
About these images

CGAP SAGE TAG: CAGACAGTTC

SOURCE GeneReport for Unigene cluster: Hs.458438
Primers: OriGene genome-wide validated SYBR primer pairs: ZNF835
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ZNF835: PPH22277A
    SABiosciences Custom PCR Arrays for ZNF835 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ZNF835 gene from 2 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
ZNF8351   -- zinc finger protein 835 80.1(n)
76.16(a)
484275  XM_541390.2  XP_541390.2 
chimpanzee
(Pan troglodytes)
ZNF8351   -- zinc finger protein 835 99.52(n)
99.46(a)
469028  XM_524413.2  XP_524413.2 
About this table        Species with no ortholog for ZNF835

ENSEMBL Gene Tree for ZNF835 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for ZNF835 gene
ZNF4972  ZNF5752  REPIN12  

ZNF835 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/162 NCBI SNPs in ZNF835 are shown (see all 162)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 19 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs39951,2
C,F,A,57177252(+) actgAC/TTTAAT 1 -- int17Minor allele frequency- T:0.46NA EA WA 256
rs18612211,2
C,F,A,H,57182917(+) CACACC/TTGCAG 1 -- int111Minor allele frequency- T:0.23NA NS EA 626
rs28700971,2
C,F,A,H,57185746(+) GAGATA/TCCACA 1 -- ng5123Minor allele frequency- T:0.46NS EA NA WA 1630
rs43271581,2
--57177525(+) TTGCCC/TAGGCT 1 -- int10--------
rs48013531,2
C,57180669(+) CGACAA/GCCCCA 1 -- int15Minor allele frequency- G:0.49EA WA NA 144
rs48013541,2
C57180910(+) GGGGGC/TCTACC 1 -- int10--------
rs48013551,2
--57180914(+) GTCTAC/TCAGGA 1 -- int10--------
rs48013561,2
--57180994(+) GCCTAC/TCAGGA 1 -- int10--------
rs48013571,2
--57181114(+) GTCTAC/TCAGGA 1 -- int10--------
rs65100091,2
C,F,A,57179956(+) CGCAGC/TGTGTG 1 -- int12Minor allele frequency- T:0.29WA 52
About this table

HapMap Linkage Disequilibrium images for ZNF835 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF835
     1 Indel: 73444

QIAGEN SeqTarget long-range PCR primers for resequencing ZNF835 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

2 PubMed articles for ZNF835 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZNF835)
  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 90485 HGNC: 34332 AceView: LOC90485 Ensembl:ENSG00000127903 euGenes: HUgn90485
ECgene: ZNF835 H-InvDB: ZNF835

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for ZNF835 gene:
Search GeneIP for patents involving ZNF835

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZNF835
 SeqTarget long-range PCR primers for resequencing ZNF835
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZNF835
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZNF835
 GenScript Custom Purified and Recombinant Proteins Services for ZNF835 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF835
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