Home
GeneCards Guide
Suite
- GeneALaCart
- GeneDecks
- GeneIP
- GeneNote
- GeneAnnot
- GeneLoc
- GeneTide
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

ZP1 Gene

protein-coding GIFtS: 49

GC11P056981

zona pellucida glycoprotein 1 (sperm receptor)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
zona pellucida glycoprotein 1 (sperm receptor)¹ ²		zona pellucida sperm-binding protein 1²
MGC87693²		Zona pellucida glycoprotein 1³
zp-1²		Zp-1³
zona pellucida protein 1²

External Ids:	HGNC: 13187¹	Entrez Gene: 22917²	Ensembl: ENSG00000149506⁷	UniProtKB: P60852³

Export aliases for ZP1 gene to outside databases

Previous GC identifers: GC11U990202 GC11P060393 GC11P060635

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZP1_HUMAN, P60852

Function: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome

reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and

ZP4. ZP1 ensures the structural integrity of the zona pellucida

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZP1 gene promoter:
         AP-1   c-Jun   NF-kappaB   c-Fos   NF-kappaB1   GATA-3   GATA-2   GATA-1   RFX1   c-Myc
         Other transcription factors

Search SABiosciences Chromatin IP Primers for ZP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.2 Ensembl cytogenetic band: 11q12.2 HGNC cytogenetic band: 11q12.2

ZP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZP1 gene location

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P056981: view genomic region (about GC identifiers)

Start:	56,981,172 bp from pter
End:	56,989,320 bp from pter
Size:	8,149 bases
Orientation:	plus strand

1 alternative location:

Chr11+ 60,635,015-60,643,164

RefSeq DNA sequence:

NC_000011.9 NT_167190.1

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ZP1_HUMAN, P60852 (See protein sequence)

Recommended Name: Zona pellucida sperm-binding protein 1 precursor

Size: 638 amino acids; 70049 Da

Subunit: Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers (By similarity)

Subcellular location: Processed zona pellucida sperm-binding protein 1: Secreted, extracellular space, extracellular

matrix

Subcellular location: Cell membrane; Single-pass type I membrane protein

Explore the universe of human proteins at neXtProt for ZP1: NX_P60852

Post-translational modifications:

Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona

pellucida¹

O-glycosylated (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_997224.2

ENSEMBL proteins:

ENSP00000278853

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates
	GenScript Custom Purified and Recombinant Proteins Services for ZP1
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005578	proteinaceous extracellular matrix	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

ZP1 for ontologies About GeneDecksing

Antibodies for ZP1:

	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ZP1
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies
	GenScript Custom Superior Antibodies Services for ZP1
	Browse antibodies at Epitomics

Assays for ZP1:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZP1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ZP1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZP1 for domains About GeneDecksing

5 InterPro domains/families:

IPR017977 Endoglin/CD105_CS

IPR000519 P_trefoil

IPR017957 P_trefoil_CS

IPR017976 Endoglin/CD105_subgr

IPR001507 Endoglin/CD105

Graphical View of Domain Structure for InterPro Entry P60852

ProtoNet protein and cluster: P60852

1 Blocks protein family: IPB000519 P-type trefoil domain

UniProtKB/Swiss-Prot: ZP1_HUMAN, P60852

Domain: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida

Similarity: Belongs to the ZP domain family. ZPB subfamily

Similarity: Contains 1 P-type (trefoil) domain

Similarity: Contains 1 ZP domain

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ZP1_HUMAN, P60852

Function: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome

reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and

ZP4. ZP1 ensures the structural integrity of the zona pellucida

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for ZP1 Sigma-Aldrich shRNA Panels and shRNA for ZP1
		OriGene 29mer shRNA kits in GFP-retroviral vector: ZP1 OriGene shRNA RFP: ZP1 OriGene basic RS shRNA: ZP1 OriGene siRNA: ZP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZP1

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZP1
		Search SABiosciences for Assays for microRNAs that regulate ZP1

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: ZP1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZP1 OriGene untagged cDNA clones in CMV expression vector: ZP1 Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: ZP1
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for ZP1

Genatlas biochemistry entry for ZP1:

zona pellucida glycoprotein 1,sperm receptor,ortholog of the mouse Zp1 gene

Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Zp1):

endocrine/exocrine gland

reproductive system

ZP1 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for ZP1

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZP1

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007338	single fertilization	IEA	--

About this table

ZP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZP1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich siRNA Panels and esiRNA and siRNA for ZP1 Sigma-Aldrich shRNA Panels and shRNA for ZP1
		OriGene 29mer shRNA kits in GFP-retroviral vector: ZP1 OriGene shRNA RFP: ZP1 OriGene basic RS shRNA: ZP1 OriGene siRNA: ZP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZP1

miRNA:		Browse microRNA Mimics at Sigma-Aldrich Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZP1
		Search SABiosciences for Assays for microRNAs that regulate ZP1

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: ZP1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ZP1 OriGene untagged cDNA clones in CMV expression vector: ZP1 Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: ZP1

Primers:		OriGene genome-wide validated SYBR primer pairs: ZP1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for ZP1: PPH13523A

REFSEQ mRNAs for ZP1 gene:

NM_207341.2

Additional cDNA sequence: BC067899.1

2 DOTS entries:

DT.204486 DT.120716059

highest scoring ESTs for ZP1:

AA890119 AA426398 AI208352 AI698605 AI766401 BC067899 BI561874 BM563794 CR741030 DA092632

Unigene Cluster for ZP1:

Zona pellucida glycoprotein 1 (sperm receptor)

Hs.172130 [show with all ESTs]

Unigene Representative Sequence: NM_207341

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for ZP1

ExUns:	1a	·	1b	^	2	^	3a	·	3b	·	3c	·	3d	·	3e	^	4	^	5	^	6a	·	6b	^	7	^	8
SP1:							-
SP2:
SP3:							-		-		-
SP4:

About this scheme

ECgene alternative splicing isoforms for ZP1
1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000278853(uc001nqd.2 uc001nqe.2)

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ZP1 expression in normal and diseased human tissues

¹ / ² / ³

3 probe-sets matching ZP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
59517_at²^{, 3}	U95-B	1	0.62	1.00	1.00	1.00	AA890119	0.60	1.00	0.82	1
237335_at²^{, 3}	U133-B	1	0.91	1.00	--	--	AA890119	0.60	1.00	0.82	1
237335_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--

About this table

ZP1 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

About these images

CGAP SAGE TAG: TAGCACTGGC

SOURCE GeneReport for Unigene cluster: Hs.172130

UniProtKB/Swiss-Prot: ZP1_HUMAN, P60852

Tissue specificity: Oocytes

Primers:		OriGene genome-wide validated SYBR primer pairs: ZP1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for ZP1: PPH13523A

SABiosciences Custom PCR Arrays for ZP1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ZP1 gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	ZP1¹	--	zona pellucida glycoprotein 1 (sperm receptor)	99.27(n) 98.59(a)	466623 XM_522022.2 XP_522022.2
rat (Rattus norvegicus)	Zp1¹	--	zona pellucida glycoprotein 1 (sperm receptor)	75.74(n) 69.51(a)	85271 XM_001075428.1 XP_001075428.1
mouse (Mus musculus)	Zp1^{1 , 5}	19 (7.36 cM)⁵	zona pellucida glycoprotein 1^{1, 5}	75.78(n)¹ 68.45(a)¹	22786¹ NM_009580.2¹ NP_033606.2¹ BC100347⁵ BC125613⁵ (see all 11)
chicken (Gallus gallus)	ZP1¹	--	zona pellucida glycoprotein 1 (sperm receptor)	63.11(n) 55.16(a)	395418 XM_001235798.1 XP_001235799.1

About this table Species with no ortholog for ZP1

ENSEMBL Gene Tree for ZP1 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ZP1 gene

ZP4² ZP2²

ZP1 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs489172^1,2	C,F,A,H,	60637164(-)	`GTGGGG/ATTGAG`	2	/T /I	ref¹ mis¹ ese³		19		NS EA NA WA	1190
rs502412^1,2	H	60640857(-)	`AGCTGA/CAGGTC`	2	C F	mis¹ ref¹ ese³		3		MN NS	412
rs544860^1,2	C,F,A	60635711(-)	`GAAACC/TCCATC`	1	--	int¹		7		EA NA WA	250
rs550479^1,2	C,H,	60635091(-)	`GTGGCG/AACCAG`	2	/V	syn¹ ref¹ ese³		5		NA	10
rs566411^1,2	C,H,	60638470(-)	`GACACC/TACGAG`	2	V	ref¹ syn¹ ese³		12		MN NS EA NA WA	612
rs576194^1,2	C,F,H,	60634594(-)	`TTAGTG/ACAGTC`	1	--	ng5¹		11		MN NS EA NA	606
rs1224036^1,2	C,	60633899(-)	`gttgcA/Ggagaa`	1	--	ng5¹ trp³		4		NA	78
rs1232553^1,2	C,H	60633532(-)	`taacaC/Tggtga`	1	--	ng5¹		4		NA	8
rs1232554^1,2	C	60633406(-)	`tgcagC/Tgagcc`	1	--	ng5¹		2		NA	4
rs1815882^1,2	--	60635495(+)	`GCCAAA/GCCTTT`	1	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for ZP1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZP1: --

QIAGEN SeqTarget long-range PCR primers for resequencing ZP1

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZP1 for disorders About GeneDecksing

OMIM: 195000

Genetic Association Database (GAD): ZP1
Human Genome Epidemiology (HuGE) Navigator: ZP1 (9 documents)

Export disorders and mutations for ZP1 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/30 PubMed articles for ZP1 gene, integrated from 7 sources (see all 30):
(articles sorted by number of sources associating them with ZP1)

Identification of the true human orthologue of the mouse Zp1 gene: evidence for greater complexity in the mammalian zona pellucida? (PubMed id 10542331)^{1, 2, 3, 7} Hughes D.C. and Barratt C.L. (1999)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)^{1, 2} Taylor T.D....Sakaki Y. (2006)
Association between sequence variations in genes encoding human zona pellucida glycoproteins and fertilization failure in IVF. (PubMed id 15860499)^{1, 4} Mannikko M....Lakkakorpi J.T. (2005)
Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia. (PubMed id 15461625)^{1, 4} Van de Water N....Harper P. (2004)
Detection of zona pellucida proteins during human folliculogenesis. (PubMed id 18033806)^{1, 7} Gook D.A....Martic M. (2008)
Four zona pellucida glycoproteins are expressed in the human. (PubMed id 15142998)^{1, 7} Lefievre L....Barratt C.L. (2004)
Study of 18 functional hemostatic polymorphisms in mu cocutaneous bleeding disorders. (PubMed id 20532885)¹ AntA^n A.I....Mezzano D. (2010)
Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)¹ Han S....Kang D. (2010)
In humans, zona pellucida glycoprotein-1 binds to spe rmatozoa and induces acrosomal exocytosis. (PubMed id 20504872)¹ Ganguly A....Gupta S.K. (2010)
Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)¹ Rajaraman P....Inskip P.D. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 22917	HGNC: 13187	Ensembl:ENSG00000149506	euGenes: HUgn22917	ECgene: ZP1
H-InvDB: ZP1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for ZP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for ZP1 gene:
Search GeneIP for patents involving ZP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ZP1		Antibodies for ZP1
	Super-pooled esiRNAs for ZP1		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ZP1		Browse microRNA Mimics at Sigma-Aldrich
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
	feedback

	Antibodies		Cell Culture Products
	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZP1
	SeqTarget long-range PCR primers for resequencing ZP1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ZP1

	GenScript Custom Purified and Recombinant Proteins Services for ZP1		GenScript cDNA clones with any tag delivered in your preferred vector for ZP1
	GenScript Custom Assay Services for ZP1		GenScript Custom Superior Antibodies Services for ZP1
	GenScript Custom overexpressing Cell Line Services for ZP1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in ZP1 promoter
	Search Chromatin IP Primers for ZP1
	RT² qPCR Primer Assay for ZP1
	Search GNC Networks for ZP1
	Search for Assays for microRNAs that regulate ZP1
	SABiosciences Custom PCR Arrays for ZP1

Search Tocris compounds for ZP1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Biologicals
	Novus Tissue Slides

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

ELISAs and CLIAs for ZP1

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

View Random Gene

Category
GIFtS Group

The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

ZP1 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

Advanced Search

Export list of displayed genes

ZP1 Gene

protein-coding GIFtS: 49

Aliases &
Descriptions
for ZP1 gene

Summaries
for ZP1 gene

Genomic Views
for ZP1 gene

Proteins
for ZP1 gene

Protein Domains/
Families
for ZP1 gene

Gene Function
for ZP1 gene

Pathways & Interactions
for ZP1 gene

Drugs & Compounds
for ZP1 gene

Transcripts
for ZP1 gene

Expression
for ZP1 gene

Orthologs
for ZP1 gene

Paralogs
for ZP1 gene

Genomic Variants
for ZP1 gene

Disorders & Mutations
for ZP1 gene

Medical News
for ZP1 gene

Publications
for ZP1 gene

External Searches for ZP1 gene

Genome Databases showing ZP1 gene

Other Databases showing ZP1 gene

Specialized Databases showing ZP1 gene

Intellectual Property
for ZP1 gene

Products
for ZP1 gene

View Random Gene

Advanced Search

Export list of displayed genes

ZP1 Gene

protein-coding GIFtS: 49

Aliases & Descriptionsfor ZP1 gene

Summariesfor ZP1 gene

Genomic Viewsfor ZP1 gene

Proteinsfor ZP1 gene

Protein Domains/Familiesfor ZP1 gene

Gene Functionfor ZP1 gene

Pathways & Interactionsfor ZP1 gene

Drugs & Compoundsfor ZP1 gene

Transcriptsfor ZP1 gene

Expression for ZP1 gene

Orthologsfor ZP1 gene

Paralogsfor ZP1 gene

Genomic Variantsfor ZP1 gene

Disorders & Mutationsfor ZP1 gene

Medical Newsfor ZP1 gene

Publicationsfor ZP1 gene

External Searches for ZP1 gene

Genome Databases showing ZP1 gene

Other Databases showing ZP1 gene

Specialized Databases showing ZP1 gene

Intellectual Propertyfor ZP1 gene

Productsfor ZP1 gene

View Random Gene

Aliases &
Descriptions
for ZP1 gene

Summaries
for ZP1 gene

Genomic Views
for ZP1 gene

Proteins
for ZP1 gene

Protein Domains/
Families
for ZP1 gene

Gene Function
for ZP1 gene

Pathways & Interactions
for ZP1 gene

Drugs & Compounds
for ZP1 gene

Transcripts
for ZP1 gene

Expression
for ZP1 gene

Orthologs
for ZP1 gene

Paralogs
for ZP1 gene

Genomic Variants
for ZP1 gene

Disorders & Mutations
for ZP1 gene

Medical News
for ZP1 gene

Publications
for ZP1 gene

Intellectual Property
for ZP1 gene

Products
for ZP1 gene