ZRSR1 Gene
pseudogene GIFtS: 32
GC05P107407
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zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
(Previous names: U2(RNU2) small nuclear RNA auxiliary factor binding protein-like, U2(RNU2) small nuclear RNA auxillary factor 1-like 1, U2 small nuclear RNA auxillary factor 1-like 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: U2AFBPL, U2AF1P, U2AF1L1)
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Aliases &
Descriptions
for ZRSR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
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|
| Aliases & Descriptions |
|---|
| zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 11 2 | | U2(RNU2) small nuclear RNA auxiliary factor binding protein-like1 | | U2AF1RS11 2 3 5 | | U2(RNU2) small nuclear RNA auxillary factor 1-like 11 | | U2AF1-RS11 2 3 | | FLJ941402 | | U2AF1P2 3 | | MGC1421592 | | U2AF1L12 3 | | CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 13 | | U2AFBPL2 3 | | U2(RNU2) small nuclear RNA auxiliary factor 1-like 13 | | U2 small nuclear RNA auxillary factor 1-like 11 | | |
Export aliases for ZRSR1 gene to outside databasesPrevious GC identifers: GC05P112256 GC05P112228 |
Summaries
for ZRSR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for ZRSR1 |
Genomic Views
for ZRSR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
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Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZRSR1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZRSR1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q22 Ensembl cytogenetic band: 5q22.2 HGNC cytogenetic band: 5q22ZRSR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P107407: view genomic region
(about GC identifiers)
Start:
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107,407,062 bp from pter |
End:
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107,408,543 bp from pter |
Size:
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1,482 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr5+ 112,227,313-112,228,791 |
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Proteins
for ZRSR1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
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|
UniProtKB/Swiss-Prot: U2AFL_HUMAN, Q15695 (See
protein sequence)Recommended Name: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 Size: 479 amino acids; 57643 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B2R901 Q13570 Q2M3R8Explore the universe of human proteins at neXtProt for ZRSR1: NX_Q15695
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
ENSEMBL proteins: ENSP00000375133
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
NAS | -- | | GO:0030529 | ribonucleoprotein complex |
IEA | -- |
About this table
ZRSR1 for ontologies About GeneDecksing
Antibodies for ZRSR1:
Assays for ZRSR1: |
Protein
Domains/
Families
for ZRSR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZRSR1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15695ProtoNet protein and cluster: Q15695 3 Blocks protein families: IPB000504 RNA-binding region RNP-1 (RNA recognition motif) IPB000571 Zn-finger IPB009145 U2 auxiliary factor small subunit signature
UniProtKB/Swiss-Prot: U2AFL_HUMAN, Q15695Similarity: Contains 2 C3H1-type zinc fingersSimilarity: Contains 1 RRM (RNA recognition motif) domain |
Gene Function
for ZRSR1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
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5 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
ZRSR1 for ontologies About GeneDecksing
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Pathways & Interactions
for ZRSR1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZRSR1
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZRSR1
1 Gene Ontology (GO) biological process term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
About this table
ZRSR1 for ontologies About GeneDecksing
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Drugs & Compounds
for ZRSR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZRSR1
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Transcripts
for ZRSR1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
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24/445 AceView cDNA sequences (see all 445): BM987992 F06453 F12337 BM791285 H08657 AA033768 F01948 BC000186 AI521838 BU155251 F06898 BF448072 BG985951 Z40684 CR592658 F04152 NM_005083 BQ182033 BM683808 CA313732 F08812 F05804 BQ431154 CA312933
 highest scoring ESTs for ZRSR1:NM_005083 AA331011 AA601026 AA669459 AW371109 AW609046 AW866867 AW876898 AW938127 BM682208
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000391338
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Expression
for ZRSR1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZRSR1 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching ZRSR1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 35060_at2, 3
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U95-A |
2 |
0.62 |
0.60 |
1.00 |
1.00 |
U51224 |
0.20 |
0.50 |
0.38 |
1 |
| 206512_at2, 3
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U133-A |
1 |
0.36 |
1.00 |
-- |
-- |
NM_005083 |
0.20 |
1.00 |
0.72 |
1 |
| 206512_at2
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U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZRSR1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SABiosciences Custom PCR Arrays for ZRSR1
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Orthologs
for ZRSR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for ZRSR1 (if available) |
Paralogs
for ZRSR1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ZRSR1 gene
- ZRSR22 U2AF12 U2AF1L42
ZRSR1 for paralogs About GeneDecksing
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Genomic Variants
for ZRSR1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
| | | QIAGEN SeqTarget long-range PCR primers for resequencing ZRSR1 |
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Disorders & Mutations
for ZRSR1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZRSR1 for disorders About GeneDecksing
OMIM: 601079
Export disorders and mutations for ZRSR1 gene to outside databases
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Medical News
for ZRSR1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZRSR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/17 PubMed articles for ZRSR1 gene, integrated from 7 sources (see all 17):
(articles sorted by number of sources associating them with ZRSR1)- Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. (PubMed id 8586425)1, 2, 7 Kitagawa K.... Mukai T. (1995)
- Absence of imprinting in U2AFBPL, a human homologue of the imprinted mouse gene U2afbp-rs. (PubMed id 8630064)1, 2 Pearsall R.S.... Held W.A. (1996)
- Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5. (PubMed id 7956352)1, 3 Kalcheva I....Takagi N. (1995)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites. (PubMed id 12558503)1 Forch P....Valcarcel J. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Nucleocytoplasmic shuttling of heterodimeric splicing factor U2AF. (PubMed id 11118443)1 Gama-Carvalho M....Carmo-Fonseca M. (2001)
- Cloning and tissue expression of cDNAs from chromosome 5q21-22 which is frequently deleted in advanced lung cancer. (PubMed id 9490301)1 Ueno K....Hosoe S. (1998)
- A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA. (PubMed id 9237760)1 Tronchere H....Fu X.D. (1997)
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External Searches for ZRSR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZRSR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ZRSR1 gene
(According to HUGE)
About This Section
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Specialized Databases showing ZRSR1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for ZRSR1 gene:
Search GeneIP for patents involving ZRSR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ZRSR1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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| |  | Search Tocris compounds for ZRSR1 |
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 | | | ELISAs and CLIAs for ZRSR1 |
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